2009-04-03
AUTHORS ABSTRACTTumour necrosis factor (TNF) was initially isolated as a factor that induced necrosis of cancer cells. However, it has become clear that TNF can also promote cancer. This Timeline examines the long history of TNF in cancer biology, asking whether it is a target, a therapeutic or both.
PAGES361-371
http://scigraph.springernature.com/pub.10.1038/nrc2628
DOIhttp://dx.doi.org/10.1038/nrc2628
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1048135560
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/19343034
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Clinical Trials as Topic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cytotoxicity, Immunologic",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA Damage",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Endotoxins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Inflammation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptors, Tumor Necrosis Factor",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Recombinant Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tumor Necrosis Factor-alpha",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Frances Balkwill is at the Centre for Cancer and Inflammation, Institute of Cancer, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Frances.balkwill@cancer.org.uk",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Frances Balkwill is at the Centre for Cancer and Inflammation, Institute of Cancer, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. Frances.balkwill@cancer.org.uk"
],
"type": "Organization"
},
"familyName": "Balkwill",
"givenName": "Frances",
"id": "sg:person.016530027317.07",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016530027317.07"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/318665a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030454113",
"https://doi.org/10.1038/318665a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6600257",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039780544",
"https://doi.org/10.1038/sj.bjc.6600257"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature06309",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000116337",
"https://doi.org/10.1038/nature06309"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature07623",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051699839",
"https://doi.org/10.1038/nature07623"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s11864-007-0044-y",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002232511",
"https://doi.org/10.1007/s11864-007-0044-y"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrd1982",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048284965",
"https://doi.org/10.1038/nrd1982"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/316552a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015056089",
"https://doi.org/10.1038/316552a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature01322",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019336134",
"https://doi.org/10.1038/nature01322"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6690335",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001346359",
"https://doi.org/10.1038/sj.bjc.6690335"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature07205",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024729982",
"https://doi.org/10.1038/nature07205"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature04808",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050989342",
"https://doi.org/10.1038/nature04808"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/bjc.1996.652",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004827175",
"https://doi.org/10.1038/bjc.1996.652"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc821",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047196539",
"https://doi.org/10.1038/nrc821"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/312724a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046917469",
"https://doi.org/10.1038/312724a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6601814",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1046963899",
"https://doi.org/10.1038/sj.bjc.6601814"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri1184",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037702320",
"https://doi.org/10.1038/nri1184"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri802",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035323400",
"https://doi.org/10.1038/nri802"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/329630a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008055718",
"https://doi.org/10.1038/329630a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/bjc.1987.294",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029580010",
"https://doi.org/10.1038/bjc.1987.294"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm1622",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015524012",
"https://doi.org/10.1038/nm1622"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nri1391",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023753307",
"https://doi.org/10.1038/nri1391"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/cgt.2008.86",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028876602",
"https://doi.org/10.1038/cgt.2008.86"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6602115",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043520791",
"https://doi.org/10.1038/sj.bjc.6602115"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/10552",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022564376",
"https://doi.org/10.1038/10552"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1207317",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010739688",
"https://doi.org/10.1038/sj.onc.1207317"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02924",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042163603",
"https://doi.org/10.1038/nature02924"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/312721a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001060520",
"https://doi.org/10.1038/312721a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10555-006-9005-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000089665",
"https://doi.org/10.1007/s10555-006-9005-3"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/bf00570490",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032993151",
"https://doi.org/10.1007/bf00570490"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/357011a0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032023099",
"https://doi.org/10.1038/357011a0"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1054/bjoc.1999.1027",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051122350",
"https://doi.org/10.1054/bjoc.1999.1027"
],
"type": "CreativeWork"
}
],
"datePublished": "2009-04-03",
"datePublishedReg": "2009-04-03",
"description": "Tumour necrosis factor (TNF) was initially isolated as a factor that induced necrosis of cancer cells. However, it has become clear that TNF can also promote cancer. This Timeline examines the long history of TNF in cancer biology, asking whether it is a target, a therapeutic or both.",
"genre": "article",
"id": "sg:pub.10.1038/nrc2628",
"inLanguage": "en",
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.2761687",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1029716",
"issn": [
"1474-175X",
"1474-1768"
],
"name": "Nature Reviews Cancer",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "5",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "9"
}
],
"keywords": [
"necrosis factor",
"cancer cells",
"TNF",
"cancer biology",
"cancer",
"necrosis",
"factors",
"therapeutics",
"cells",
"target",
"history",
"long history",
"biology",
"timeline"
],
"name": "Tumour necrosis factor and cancer",
"pagination": "361-371",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1048135560"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/nrc2628"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"19343034"
]
}
],
"sameAs": [
"https://doi.org/10.1038/nrc2628",
"https://app.dimensions.ai/details/publication/pub.1048135560"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-10T09:58",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220509/entities/gbq_results/article/article_487.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/nrc2628"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrc2628'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrc2628'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrc2628'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrc2628'
This table displays all metadata directly associated to this object as RDF triples.
246 TRIPLES
22 PREDICATES
82 URIs
43 LITERALS
18 BLANK NODES