Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype? View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2007-06

AUTHORS

Héctor Peinado, David Olmeda, Amparo Cano

ABSTRACT

The molecular mechanisms that underlie tumour progression are still poorly understood, but recently our knowledge of particular aspects of some of these processes has increased. Specifically, the identification of Snail, ZEB and some basic helix-loop-helix (bHLH) factors as inducers of epithelial-mesenchymal transition (EMT) and potent repressors of E-cadherin expression has opened new avenues of research with potential clinical implications. More... »

PAGES

415-428

References to SciGraph publications

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrc2131

    DOI

    http://dx.doi.org/10.1038/nrc2131

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1025092385

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17508028


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