Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-08

AUTHORS

Eugenia E Calle, Rudolf Kaaks

ABSTRACT

The prevalence of obesity is rapidly increasing globally. Epidemiological studies have associated obesity with a range of cancer types, although the mechanisms by which obesity induces or promotes tumorigenesis vary by cancer site. These include insulin resistance and resultant chronic hyperinsulinaemia, increased bioavailability of steroid hormones and localized inflammation. Gaining a better understanding of the relationship between obesity and cancer can provide new insight into mechanisms of cancer pathogenesis. More... »

PAGES

579-591

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nrc1408

    DOI

    http://dx.doi.org/10.1038/nrc1408

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1022040392

    PUBMED

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