The anti-angiogenic basis of metronomic chemotherapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2004-06

AUTHORS

Robert S Kerbel, Barton A Kamen

ABSTRACT

In addition to proliferating cancer cells and various types of normal cells, such as those of the bone marrow, conventional cytotoxic chemotherapeutics affect the endothelium of the growing tumour vasculature. The anti-angiogenic efficacy of chemotherapy seems to be optimized by administering comparatively low doses of drug on a frequent or continuous schedule, with no extended interruptions — sometimes referred to as 'metronomic' chemotherapy. In addition to reduced acute toxicity, the efficacy of metronomic chemotherapy seems to increase when administered in combination with specific anti-angiogenic drugs. Gaining better insight into the mechanisms of these effects could lessen or even eliminate the empiricism used to determine the optimal dose and schedule for metronomic chemotherapy regimens. More... »

PAGES

423-436

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nrc1369

DOI

http://dx.doi.org/10.1038/nrc1369

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1019159796

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/15170445


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Oncology and Carcinogenesis", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Angiogenesis Inhibitors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Antineoplastic Combined Chemotherapy Protocols", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Dose-Response Relationship, Drug", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Drug Administration Schedule", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Neovascularization, Pathologic", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Sunnybrook Health Science Centre", 
          "id": "https://www.grid.ac/institutes/grid.413104.3", 
          "name": [
            "Molecular and Cellular Biology Research, Sunnybrook and Women's College Health Sciences Centre, S-217, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. RSKerbel@aol.com"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kerbel", 
        "givenName": "Robert S", 
        "id": "sg:person.0673064574.73", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673064574.73"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kamen", 
        "givenName": "Barton A", 
        "id": "sg:person.0616713135.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616713135.35"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s004170050387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000133235", 
          "https://doi.org/10.1007/s004170050387"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/anr.1780320903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000341814"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdf013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003073567"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003700365", 
          "https://doi.org/10.1038/nm988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm988", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003700365", 
          "https://doi.org/10.1038/nm988"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-04-0265", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004576540"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(00)00693-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005004839"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jtbi.2003.3162", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005111562"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199107183250305", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005599331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ju.0000075917.98929.57", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006156218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.ju.0000075917.98929.57", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006156218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa032792", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009565945"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(20010901)92:5<1259::aid-cncr1446>3.0.co;2-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010712632"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1080/1042819021000032926", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010723500"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdf093", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011228612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1095-1024", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011626141", 
          "https://doi.org/10.1038/nm1095-1024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013556778", 
          "https://doi.org/10.1038/7434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7434", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013556778", 
          "https://doi.org/10.1038/7434"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11912-996-0009-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014855475", 
          "https://doi.org/10.1007/s11912-996-0009-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc925", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015283659", 
          "https://doi.org/10.1038/nrc925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc925", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015283659", 
          "https://doi.org/10.1038/nrc925"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/jpsu.2001.28823", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015441431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/jpsu.2001.25747", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015709867"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.10634", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017062774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199205283262203", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017332577"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci9872", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018143975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bies.950130106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018594587"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1203/00006450-200205000-00011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019540076", 
          "https://doi.org/10.1203/00006450-200205000-00011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1009018702832", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020650340", 
          "https://doi.org/10.1023/a:1009018702832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1535-6108(03)00245-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020981872"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci5028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022103776"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/71517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022770960", 
          "https://doi.org/10.1038/71517"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/71517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022770960", 
          "https://doi.org/10.1038/71517"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/28412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023139355", 
          "https://doi.org/10.1038/28412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/28412", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023139355", 
          "https://doi.org/10.1038/28412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0002-9440(10)64131-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023969147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1582-4934.2002.tb00307.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024917485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrd819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025321199", 
          "https://doi.org/10.1038/nrd819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrd819", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025321199", 
          "https://doi.org/10.1038/nrd819"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1471-4914(01)02102-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026515921"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-03-3391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027847659"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1535-6108(03)00240-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028635692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.46.30336", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030188573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(19891015)64:8<1577::aid-cncr2820640803>3.0.co;2-i", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030658768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.10907", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031444244"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm200103153441101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031768583"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/annonc/mdf027", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031858527"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200308000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032165401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200308000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032165401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejm199710303371802", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033441907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.11709", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033777265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00300241", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033779853", 
          "https://doi.org/10.1007/bf00300241"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1999.1589", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034960856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/416279b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035406433", 
          "https://doi.org/10.1038/416279b"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/416279b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035406433", 
          "https://doi.org/10.1038/416279b"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci8829", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036426384"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.072586399", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037097699"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1010635000879", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037266095", 
          "https://doi.org/10.1023/a:1010635000879"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/cncr.11713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038670473"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0753-3322(05)80059-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039426415"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1005718628223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039483673", 
          "https://doi.org/10.1023/a:1005718628223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2003-01-0223", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039774871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200301000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040961418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00001813-200301000-00003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040961418"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-04-0580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041229486"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.270.17.9709", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042624719"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.138.3.707", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043876573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/1097-0142(20001201)89:11<2309::aid-cncr20>3.0.co;2-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044145849"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4419-8871-3_19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044599973", 
          "https://doi.org/10.1007/978-1-4419-8871-3_19"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-1-4419-8871-3_19", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044599973", 
          "https://doi.org/10.1007/978-1-4419-8871-3_19"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2003-02-0365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045288676"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00280-003-0678-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045499379", 
          "https://doi.org/10.1007/s00280-003-0678-9"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-03-3126", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047832996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/95.24.1820", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048254906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6601259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048771245", 
          "https://doi.org/10.1038/sj.bjc.6601259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.bjc.6601259", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048771245", 
          "https://doi.org/10.1038/sj.bjc.6601259"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1470-2045(01)00587-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048951760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0305-7372(97)90019-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049471028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1009053411094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049623096", 
          "https://doi.org/10.1023/a:1009053411094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.2135406100", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050157278"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1006094117427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050230898", 
          "https://doi.org/10.1023/a:1006094117427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1101-1194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050308225", 
          "https://doi.org/10.1038/nm1101-1194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1101-1194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050308225", 
          "https://doi.org/10.1038/nm1101-1194"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000071373", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050628817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa011954", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052159806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.07.060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052822724"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1023/a:1008497110734", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056303856"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/94.2.82", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059820954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jnci/95.4.254", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059821258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199706000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199706000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199706000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199706000-00022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199810000-00018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199810000-00018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00000421-199810000-00018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060113788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/sqb.2002.67.293", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060415905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1068327", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062445812"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1082504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062447938"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5302.964", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062555783"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.02.061", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203391"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.08.092", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203798"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.09.081", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203847"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.10.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064203892"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2003.12.068", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064204008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1542/peds.103.6.1145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067819985"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/1389450013348597", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069180035"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/or.10.5.1213", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071528893"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074465013", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074495004", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074511198", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074515788", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074526310", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074539501", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074559950", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2000.18.6.1212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074604319"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074608440", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074608455", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074623639", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2000.18.16.2935", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074684743"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074750381", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.4.1195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074754844"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074801130", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2001.19.12.3091", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074835662"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074896157", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074949027", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074950186", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074984083", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075025301", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075055329", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2002.20.17.3574", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075115180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075198244", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107327480301000105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075241335"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/107327480301000105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1075241335"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075243422", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075279931", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075298781", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075329243", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076062843", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076585345", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076595659", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076613584", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1076633385", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1077477084", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.1997.15.1.187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083031480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083083410", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083186038", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083347625", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083370636", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2004.22.14_suppl.610", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1084615035"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2004-06", 
    "datePublishedReg": "2004-06-01", 
    "description": "In addition to proliferating cancer cells and various types of normal cells, such as those of the bone marrow, conventional cytotoxic chemotherapeutics affect the endothelium of the growing tumour vasculature. The anti-angiogenic efficacy of chemotherapy seems to be optimized by administering comparatively low doses of drug on a frequent or continuous schedule, with no extended interruptions \u2014 sometimes referred to as 'metronomic' chemotherapy. In addition to reduced acute toxicity, the efficacy of metronomic chemotherapy seems to increase when administered in combination with specific anti-angiogenic drugs. Gaining better insight into the mechanisms of these effects could lessen or even eliminate the empiricism used to determine the optimal dose and schedule for metronomic chemotherapy regimens.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nrc1369", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1029716", 
        "issn": [
          "1474-175X", 
          "1474-1768"
        ], 
        "name": "Nature Reviews Cancer", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "4"
      }
    ], 
    "name": "The anti-angiogenic basis of metronomic chemotherapy", 
    "pagination": "423-436", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "5b4a08dbb69940738936954e4c42402ac42700d4a4752d4ea4d5654e1286ca78"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "15170445"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101124168"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nrc1369"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1019159796"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nrc1369", 
      "https://app.dimensions.ai/details/publication/pub.1019159796"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:05", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000360_0000000360/records_118327_00000000.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/nrc/journal/v4/n6/full/nrc1369.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nrc1369'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nrc1369'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nrc1369'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nrc1369'


 

This table displays all metadata directly associated to this object as RDF triples.

484 TRIPLES      21 PREDICATES      167 URIs      28 LITERALS      16 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nrc1369 schema:about N1f97d110502345628daccb8503bdf4f7
2 N36a89ab5a2204ec885e19bfdec5be39f
3 N37f0dce436c14e319a77a7e70c950b2e
4 N4fa0da51d60e47d8800e39c1dbd1f7d5
5 N866f786f173e42cd9ddb0436600d1267
6 Nb9cece4dcb684d35a59fb4fcdd8bfe86
7 Nc6f7862e341a48c1993fa637b33b3bf4
8 anzsrc-for:11
9 anzsrc-for:1112
10 schema:author N96efd029a06c45c5ba1aa72fd0456617
11 schema:citation sg:pub.10.1007/978-1-4419-8871-3_19
12 sg:pub.10.1007/bf00300241
13 sg:pub.10.1007/s00280-003-0678-9
14 sg:pub.10.1007/s004170050387
15 sg:pub.10.1007/s11912-996-0009-5
16 sg:pub.10.1023/a:1005718628223
17 sg:pub.10.1023/a:1006094117427
18 sg:pub.10.1023/a:1009018702832
19 sg:pub.10.1023/a:1009053411094
20 sg:pub.10.1023/a:1010635000879
21 sg:pub.10.1038/28412
22 sg:pub.10.1038/416279b
23 sg:pub.10.1038/71517
24 sg:pub.10.1038/7434
25 sg:pub.10.1038/nm1095-1024
26 sg:pub.10.1038/nm1101-1194
27 sg:pub.10.1038/nm988
28 sg:pub.10.1038/nrc925
29 sg:pub.10.1038/nrd819
30 sg:pub.10.1038/sj.bjc.6601259
31 sg:pub.10.1203/00006450-200205000-00011
32 https://app.dimensions.ai/details/publication/pub.1074465013
33 https://app.dimensions.ai/details/publication/pub.1074495004
34 https://app.dimensions.ai/details/publication/pub.1074511198
35 https://app.dimensions.ai/details/publication/pub.1074515788
36 https://app.dimensions.ai/details/publication/pub.1074526310
37 https://app.dimensions.ai/details/publication/pub.1074539501
38 https://app.dimensions.ai/details/publication/pub.1074559950
39 https://app.dimensions.ai/details/publication/pub.1074608440
40 https://app.dimensions.ai/details/publication/pub.1074608455
41 https://app.dimensions.ai/details/publication/pub.1074623639
42 https://app.dimensions.ai/details/publication/pub.1074750381
43 https://app.dimensions.ai/details/publication/pub.1074801130
44 https://app.dimensions.ai/details/publication/pub.1074896157
45 https://app.dimensions.ai/details/publication/pub.1074949027
46 https://app.dimensions.ai/details/publication/pub.1074950186
47 https://app.dimensions.ai/details/publication/pub.1074984083
48 https://app.dimensions.ai/details/publication/pub.1075025301
49 https://app.dimensions.ai/details/publication/pub.1075055329
50 https://app.dimensions.ai/details/publication/pub.1075198244
51 https://app.dimensions.ai/details/publication/pub.1075243422
52 https://app.dimensions.ai/details/publication/pub.1075279931
53 https://app.dimensions.ai/details/publication/pub.1075298781
54 https://app.dimensions.ai/details/publication/pub.1075329243
55 https://app.dimensions.ai/details/publication/pub.1076062843
56 https://app.dimensions.ai/details/publication/pub.1076585345
57 https://app.dimensions.ai/details/publication/pub.1076595659
58 https://app.dimensions.ai/details/publication/pub.1076613584
59 https://app.dimensions.ai/details/publication/pub.1076633385
60 https://app.dimensions.ai/details/publication/pub.1077477084
61 https://app.dimensions.ai/details/publication/pub.1083083410
62 https://app.dimensions.ai/details/publication/pub.1083186038
63 https://app.dimensions.ai/details/publication/pub.1083347625
64 https://app.dimensions.ai/details/publication/pub.1083370636
65 https://doi.org/10.1002/1097-0142(19891015)64:8<1577::aid-cncr2820640803>3.0.co;2-i
66 https://doi.org/10.1002/1097-0142(20001201)89:11<2309::aid-cncr20>3.0.co;2-8
67 https://doi.org/10.1002/1097-0142(20010901)92:5<1259::aid-cncr1446>3.0.co;2-y
68 https://doi.org/10.1002/anr.1780320903
69 https://doi.org/10.1002/bies.950130106
70 https://doi.org/10.1002/cncr.10634
71 https://doi.org/10.1002/cncr.11709
72 https://doi.org/10.1002/cncr.11713
73 https://doi.org/10.1002/ijc.10907
74 https://doi.org/10.1006/bbrc.1999.1589
75 https://doi.org/10.1006/jtbi.2003.3162
76 https://doi.org/10.1016/s0002-9440(10)64131-4
77 https://doi.org/10.1016/s0024-3205(00)00693-7
78 https://doi.org/10.1016/s0305-7372(97)90019-0
79 https://doi.org/10.1016/s0753-3322(05)80059-9
80 https://doi.org/10.1016/s1470-2045(01)00587-3
81 https://doi.org/10.1016/s1471-4914(01)02102-5
82 https://doi.org/10.1016/s1535-6108(03)00240-x
83 https://doi.org/10.1016/s1535-6108(03)00245-9
84 https://doi.org/10.1023/a:1008497110734
85 https://doi.org/10.1053/jpsu.2001.25747
86 https://doi.org/10.1053/jpsu.2001.28823
87 https://doi.org/10.1056/nejm199107183250305
88 https://doi.org/10.1056/nejm199205283262203
89 https://doi.org/10.1056/nejm199710303371802
90 https://doi.org/10.1056/nejm200103153441101
91 https://doi.org/10.1056/nejmoa011954
92 https://doi.org/10.1056/nejmoa032792
93 https://doi.org/10.1073/pnas.072586399
94 https://doi.org/10.1073/pnas.2135406100
95 https://doi.org/10.1074/jbc.270.17.9709
96 https://doi.org/10.1074/jbc.273.46.30336
97 https://doi.org/10.1080/1042819021000032926
98 https://doi.org/10.1083/jcb.138.3.707
99 https://doi.org/10.1093/annonc/mdf013
100 https://doi.org/10.1093/annonc/mdf027
101 https://doi.org/10.1093/annonc/mdf093
102 https://doi.org/10.1093/jnci/94.2.82
103 https://doi.org/10.1093/jnci/95.24.1820
104 https://doi.org/10.1093/jnci/95.4.254
105 https://doi.org/10.1097/00000421-199706000-00022
106 https://doi.org/10.1097/00000421-199810000-00018
107 https://doi.org/10.1097/00001813-200301000-00003
108 https://doi.org/10.1097/00001813-200308000-00003
109 https://doi.org/10.1097/01.ju.0000075917.98929.57
110 https://doi.org/10.1101/sqb.2002.67.293
111 https://doi.org/10.1111/j.1582-4934.2002.tb00307.x
112 https://doi.org/10.1126/science.1068327
113 https://doi.org/10.1126/science.1082504
114 https://doi.org/10.1126/science.275.5302.964
115 https://doi.org/10.1158/0008-5472.can-03-3126
116 https://doi.org/10.1158/0008-5472.can-03-3391
117 https://doi.org/10.1158/0008-5472.can-04-0265
118 https://doi.org/10.1158/0008-5472.can-04-0580
119 https://doi.org/10.1159/000071373
120 https://doi.org/10.1172/jci5028
121 https://doi.org/10.1172/jci8829
122 https://doi.org/10.1172/jci9872
123 https://doi.org/10.1177/107327480301000105
124 https://doi.org/10.1182/blood-2003-01-0223
125 https://doi.org/10.1182/blood-2003-02-0365
126 https://doi.org/10.1200/jco.1997.15.1.187
127 https://doi.org/10.1200/jco.2000.18.16.2935
128 https://doi.org/10.1200/jco.2000.18.6.1212
129 https://doi.org/10.1200/jco.2001.19.12.3091
130 https://doi.org/10.1200/jco.2001.19.4.1195
131 https://doi.org/10.1200/jco.2002.20.17.3574
132 https://doi.org/10.1200/jco.2003.02.061
133 https://doi.org/10.1200/jco.2003.08.092
134 https://doi.org/10.1200/jco.2003.09.081
135 https://doi.org/10.1200/jco.2003.10.039
136 https://doi.org/10.1200/jco.2003.12.068
137 https://doi.org/10.1200/jco.2004.07.060
138 https://doi.org/10.1200/jco.2004.22.14_suppl.610
139 https://doi.org/10.1542/peds.103.6.1145
140 https://doi.org/10.2174/1389450013348597
141 https://doi.org/10.3892/or.10.5.1213
142 schema:datePublished 2004-06
143 schema:datePublishedReg 2004-06-01
144 schema:description In addition to proliferating cancer cells and various types of normal cells, such as those of the bone marrow, conventional cytotoxic chemotherapeutics affect the endothelium of the growing tumour vasculature. The anti-angiogenic efficacy of chemotherapy seems to be optimized by administering comparatively low doses of drug on a frequent or continuous schedule, with no extended interruptions — sometimes referred to as 'metronomic' chemotherapy. In addition to reduced acute toxicity, the efficacy of metronomic chemotherapy seems to increase when administered in combination with specific anti-angiogenic drugs. Gaining better insight into the mechanisms of these effects could lessen or even eliminate the empiricism used to determine the optimal dose and schedule for metronomic chemotherapy regimens.
145 schema:genre research_article
146 schema:inLanguage en
147 schema:isAccessibleForFree false
148 schema:isPartOf Na4dc134c0ef54c2f85a1b09fe1c1168d
149 Nd91655a28e2c4cd18b2f5bc5a3448e88
150 sg:journal.1029716
151 schema:name The anti-angiogenic basis of metronomic chemotherapy
152 schema:pagination 423-436
153 schema:productId N4202b8a008324fe2a75caf1281552310
154 Nad58a0086777445888ea10ebef1a7592
155 Nc4e26066a7034b5a96ff779bec66f0ee
156 Neeb918a546bf441cb6aecd543433278e
157 Nf1718fbdcc274403b81c6f2a6f4e83ad
158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019159796
159 https://doi.org/10.1038/nrc1369
160 schema:sdDatePublished 2019-04-11T12:05
161 schema:sdLicense https://scigraph.springernature.com/explorer/license/
162 schema:sdPublisher Nff660ff4b2b349978c1080caf9cf96bc
163 schema:url http://www.nature.com/nrc/journal/v4/n6/full/nrc1369.html
164 sgo:license sg:explorer/license/
165 sgo:sdDataset articles
166 rdf:type schema:ScholarlyArticle
167 N1f97d110502345628daccb8503bdf4f7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
168 schema:name Angiogenesis Inhibitors
169 rdf:type schema:DefinedTerm
170 N36a89ab5a2204ec885e19bfdec5be39f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
171 schema:name Drug Administration Schedule
172 rdf:type schema:DefinedTerm
173 N37f0dce436c14e319a77a7e70c950b2e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
174 schema:name Antineoplastic Combined Chemotherapy Protocols
175 rdf:type schema:DefinedTerm
176 N4202b8a008324fe2a75caf1281552310 schema:name doi
177 schema:value 10.1038/nrc1369
178 rdf:type schema:PropertyValue
179 N4fa0da51d60e47d8800e39c1dbd1f7d5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
180 schema:name Neovascularization, Pathologic
181 rdf:type schema:DefinedTerm
182 N866f786f173e42cd9ddb0436600d1267 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
183 schema:name Dose-Response Relationship, Drug
184 rdf:type schema:DefinedTerm
185 N90cac63d93b142a1b202825d77dd92c2 rdf:first sg:person.0616713135.35
186 rdf:rest rdf:nil
187 N96efd029a06c45c5ba1aa72fd0456617 rdf:first sg:person.0673064574.73
188 rdf:rest N90cac63d93b142a1b202825d77dd92c2
189 Na4dc134c0ef54c2f85a1b09fe1c1168d schema:volumeNumber 4
190 rdf:type schema:PublicationVolume
191 Nad58a0086777445888ea10ebef1a7592 schema:name readcube_id
192 schema:value 5b4a08dbb69940738936954e4c42402ac42700d4a4752d4ea4d5654e1286ca78
193 rdf:type schema:PropertyValue
194 Nb9cece4dcb684d35a59fb4fcdd8bfe86 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
195 schema:name Humans
196 rdf:type schema:DefinedTerm
197 Nc4e26066a7034b5a96ff779bec66f0ee schema:name dimensions_id
198 schema:value pub.1019159796
199 rdf:type schema:PropertyValue
200 Nc6f7862e341a48c1993fa637b33b3bf4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
201 schema:name Neoplasms
202 rdf:type schema:DefinedTerm
203 Nd91655a28e2c4cd18b2f5bc5a3448e88 schema:issueNumber 6
204 rdf:type schema:PublicationIssue
205 Neeb918a546bf441cb6aecd543433278e schema:name pubmed_id
206 schema:value 15170445
207 rdf:type schema:PropertyValue
208 Nf1718fbdcc274403b81c6f2a6f4e83ad schema:name nlm_unique_id
209 schema:value 101124168
210 rdf:type schema:PropertyValue
211 Nff660ff4b2b349978c1080caf9cf96bc schema:name Springer Nature - SN SciGraph project
212 rdf:type schema:Organization
213 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
214 schema:name Medical and Health Sciences
215 rdf:type schema:DefinedTerm
216 anzsrc-for:1112 schema:inDefinedTermSet anzsrc-for:
217 schema:name Oncology and Carcinogenesis
218 rdf:type schema:DefinedTerm
219 sg:journal.1029716 schema:issn 1474-175X
220 1474-1768
221 schema:name Nature Reviews Cancer
222 rdf:type schema:Periodical
223 sg:person.0616713135.35 schema:familyName Kamen
224 schema:givenName Barton A
225 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0616713135.35
226 rdf:type schema:Person
227 sg:person.0673064574.73 schema:affiliation https://www.grid.ac/institutes/grid.413104.3
228 schema:familyName Kerbel
229 schema:givenName Robert S
230 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673064574.73
231 rdf:type schema:Person
232 sg:pub.10.1007/978-1-4419-8871-3_19 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044599973
233 https://doi.org/10.1007/978-1-4419-8871-3_19
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/bf00300241 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033779853
236 https://doi.org/10.1007/bf00300241
237 rdf:type schema:CreativeWork
238 sg:pub.10.1007/s00280-003-0678-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045499379
239 https://doi.org/10.1007/s00280-003-0678-9
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/s004170050387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000133235
242 https://doi.org/10.1007/s004170050387
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/s11912-996-0009-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014855475
245 https://doi.org/10.1007/s11912-996-0009-5
246 rdf:type schema:CreativeWork
247 sg:pub.10.1023/a:1005718628223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039483673
248 https://doi.org/10.1023/a:1005718628223
249 rdf:type schema:CreativeWork
250 sg:pub.10.1023/a:1006094117427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050230898
251 https://doi.org/10.1023/a:1006094117427
252 rdf:type schema:CreativeWork
253 sg:pub.10.1023/a:1009018702832 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020650340
254 https://doi.org/10.1023/a:1009018702832
255 rdf:type schema:CreativeWork
256 sg:pub.10.1023/a:1009053411094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049623096
257 https://doi.org/10.1023/a:1009053411094
258 rdf:type schema:CreativeWork
259 sg:pub.10.1023/a:1010635000879 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037266095
260 https://doi.org/10.1023/a:1010635000879
261 rdf:type schema:CreativeWork
262 sg:pub.10.1038/28412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023139355
263 https://doi.org/10.1038/28412
264 rdf:type schema:CreativeWork
265 sg:pub.10.1038/416279b schema:sameAs https://app.dimensions.ai/details/publication/pub.1035406433
266 https://doi.org/10.1038/416279b
267 rdf:type schema:CreativeWork
268 sg:pub.10.1038/71517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022770960
269 https://doi.org/10.1038/71517
270 rdf:type schema:CreativeWork
271 sg:pub.10.1038/7434 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013556778
272 https://doi.org/10.1038/7434
273 rdf:type schema:CreativeWork
274 sg:pub.10.1038/nm1095-1024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011626141
275 https://doi.org/10.1038/nm1095-1024
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/nm1101-1194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050308225
278 https://doi.org/10.1038/nm1101-1194
279 rdf:type schema:CreativeWork
280 sg:pub.10.1038/nm988 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003700365
281 https://doi.org/10.1038/nm988
282 rdf:type schema:CreativeWork
283 sg:pub.10.1038/nrc925 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015283659
284 https://doi.org/10.1038/nrc925
285 rdf:type schema:CreativeWork
286 sg:pub.10.1038/nrd819 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025321199
287 https://doi.org/10.1038/nrd819
288 rdf:type schema:CreativeWork
289 sg:pub.10.1038/sj.bjc.6601259 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048771245
290 https://doi.org/10.1038/sj.bjc.6601259
291 rdf:type schema:CreativeWork
292 sg:pub.10.1203/00006450-200205000-00011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019540076
293 https://doi.org/10.1203/00006450-200205000-00011
294 rdf:type schema:CreativeWork
295 https://app.dimensions.ai/details/publication/pub.1074465013 schema:CreativeWork
296 https://app.dimensions.ai/details/publication/pub.1074495004 schema:CreativeWork
297 https://app.dimensions.ai/details/publication/pub.1074511198 schema:CreativeWork
298 https://app.dimensions.ai/details/publication/pub.1074515788 schema:CreativeWork
299 https://app.dimensions.ai/details/publication/pub.1074526310 schema:CreativeWork
300 https://app.dimensions.ai/details/publication/pub.1074539501 schema:CreativeWork
301 https://app.dimensions.ai/details/publication/pub.1074559950 schema:CreativeWork
302 https://app.dimensions.ai/details/publication/pub.1074608440 schema:CreativeWork
303 https://app.dimensions.ai/details/publication/pub.1074608455 schema:CreativeWork
304 https://app.dimensions.ai/details/publication/pub.1074623639 schema:CreativeWork
305 https://app.dimensions.ai/details/publication/pub.1074750381 schema:CreativeWork
306 https://app.dimensions.ai/details/publication/pub.1074801130 schema:CreativeWork
307 https://app.dimensions.ai/details/publication/pub.1074896157 schema:CreativeWork
308 https://app.dimensions.ai/details/publication/pub.1074949027 schema:CreativeWork
309 https://app.dimensions.ai/details/publication/pub.1074950186 schema:CreativeWork
310 https://app.dimensions.ai/details/publication/pub.1074984083 schema:CreativeWork
311 https://app.dimensions.ai/details/publication/pub.1075025301 schema:CreativeWork
312 https://app.dimensions.ai/details/publication/pub.1075055329 schema:CreativeWork
313 https://app.dimensions.ai/details/publication/pub.1075198244 schema:CreativeWork
314 https://app.dimensions.ai/details/publication/pub.1075243422 schema:CreativeWork
315 https://app.dimensions.ai/details/publication/pub.1075279931 schema:CreativeWork
316 https://app.dimensions.ai/details/publication/pub.1075298781 schema:CreativeWork
317 https://app.dimensions.ai/details/publication/pub.1075329243 schema:CreativeWork
318 https://app.dimensions.ai/details/publication/pub.1076062843 schema:CreativeWork
319 https://app.dimensions.ai/details/publication/pub.1076585345 schema:CreativeWork
320 https://app.dimensions.ai/details/publication/pub.1076595659 schema:CreativeWork
321 https://app.dimensions.ai/details/publication/pub.1076613584 schema:CreativeWork
322 https://app.dimensions.ai/details/publication/pub.1076633385 schema:CreativeWork
323 https://app.dimensions.ai/details/publication/pub.1077477084 schema:CreativeWork
324 https://app.dimensions.ai/details/publication/pub.1083083410 schema:CreativeWork
325 https://app.dimensions.ai/details/publication/pub.1083186038 schema:CreativeWork
326 https://app.dimensions.ai/details/publication/pub.1083347625 schema:CreativeWork
327 https://app.dimensions.ai/details/publication/pub.1083370636 schema:CreativeWork
328 https://doi.org/10.1002/1097-0142(19891015)64:8<1577::aid-cncr2820640803>3.0.co;2-i schema:sameAs https://app.dimensions.ai/details/publication/pub.1030658768
329 rdf:type schema:CreativeWork
330 https://doi.org/10.1002/1097-0142(20001201)89:11<2309::aid-cncr20>3.0.co;2-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044145849
331 rdf:type schema:CreativeWork
332 https://doi.org/10.1002/1097-0142(20010901)92:5<1259::aid-cncr1446>3.0.co;2-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1010712632
333 rdf:type schema:CreativeWork
334 https://doi.org/10.1002/anr.1780320903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000341814
335 rdf:type schema:CreativeWork
336 https://doi.org/10.1002/bies.950130106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018594587
337 rdf:type schema:CreativeWork
338 https://doi.org/10.1002/cncr.10634 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017062774
339 rdf:type schema:CreativeWork
340 https://doi.org/10.1002/cncr.11709 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033777265
341 rdf:type schema:CreativeWork
342 https://doi.org/10.1002/cncr.11713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038670473
343 rdf:type schema:CreativeWork
344 https://doi.org/10.1002/ijc.10907 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031444244
345 rdf:type schema:CreativeWork
346 https://doi.org/10.1006/bbrc.1999.1589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034960856
347 rdf:type schema:CreativeWork
348 https://doi.org/10.1006/jtbi.2003.3162 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005111562
349 rdf:type schema:CreativeWork
350 https://doi.org/10.1016/s0002-9440(10)64131-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023969147
351 rdf:type schema:CreativeWork
352 https://doi.org/10.1016/s0024-3205(00)00693-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005004839
353 rdf:type schema:CreativeWork
354 https://doi.org/10.1016/s0305-7372(97)90019-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049471028
355 rdf:type schema:CreativeWork
356 https://doi.org/10.1016/s0753-3322(05)80059-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039426415
357 rdf:type schema:CreativeWork
358 https://doi.org/10.1016/s1470-2045(01)00587-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048951760
359 rdf:type schema:CreativeWork
360 https://doi.org/10.1016/s1471-4914(01)02102-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026515921
361 rdf:type schema:CreativeWork
362 https://doi.org/10.1016/s1535-6108(03)00240-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028635692
363 rdf:type schema:CreativeWork
364 https://doi.org/10.1016/s1535-6108(03)00245-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020981872
365 rdf:type schema:CreativeWork
366 https://doi.org/10.1023/a:1008497110734 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056303856
367 rdf:type schema:CreativeWork
368 https://doi.org/10.1053/jpsu.2001.25747 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015709867
369 rdf:type schema:CreativeWork
370 https://doi.org/10.1053/jpsu.2001.28823 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015441431
371 rdf:type schema:CreativeWork
372 https://doi.org/10.1056/nejm199107183250305 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005599331
373 rdf:type schema:CreativeWork
374 https://doi.org/10.1056/nejm199205283262203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017332577
375 rdf:type schema:CreativeWork
376 https://doi.org/10.1056/nejm199710303371802 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033441907
377 rdf:type schema:CreativeWork
378 https://doi.org/10.1056/nejm200103153441101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031768583
379 rdf:type schema:CreativeWork
380 https://doi.org/10.1056/nejmoa011954 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052159806
381 rdf:type schema:CreativeWork
382 https://doi.org/10.1056/nejmoa032792 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009565945
383 rdf:type schema:CreativeWork
384 https://doi.org/10.1073/pnas.072586399 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037097699
385 rdf:type schema:CreativeWork
386 https://doi.org/10.1073/pnas.2135406100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050157278
387 rdf:type schema:CreativeWork
388 https://doi.org/10.1074/jbc.270.17.9709 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042624719
389 rdf:type schema:CreativeWork
390 https://doi.org/10.1074/jbc.273.46.30336 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030188573
391 rdf:type schema:CreativeWork
392 https://doi.org/10.1080/1042819021000032926 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010723500
393 rdf:type schema:CreativeWork
394 https://doi.org/10.1083/jcb.138.3.707 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043876573
395 rdf:type schema:CreativeWork
396 https://doi.org/10.1093/annonc/mdf013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003073567
397 rdf:type schema:CreativeWork
398 https://doi.org/10.1093/annonc/mdf027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031858527
399 rdf:type schema:CreativeWork
400 https://doi.org/10.1093/annonc/mdf093 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011228612
401 rdf:type schema:CreativeWork
402 https://doi.org/10.1093/jnci/94.2.82 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059820954
403 rdf:type schema:CreativeWork
404 https://doi.org/10.1093/jnci/95.24.1820 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048254906
405 rdf:type schema:CreativeWork
406 https://doi.org/10.1093/jnci/95.4.254 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059821258
407 rdf:type schema:CreativeWork
408 https://doi.org/10.1097/00000421-199706000-00022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060113599
409 rdf:type schema:CreativeWork
410 https://doi.org/10.1097/00000421-199810000-00018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060113788
411 rdf:type schema:CreativeWork
412 https://doi.org/10.1097/00001813-200301000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040961418
413 rdf:type schema:CreativeWork
414 https://doi.org/10.1097/00001813-200308000-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032165401
415 rdf:type schema:CreativeWork
416 https://doi.org/10.1097/01.ju.0000075917.98929.57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006156218
417 rdf:type schema:CreativeWork
418 https://doi.org/10.1101/sqb.2002.67.293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060415905
419 rdf:type schema:CreativeWork
420 https://doi.org/10.1111/j.1582-4934.2002.tb00307.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1024917485
421 rdf:type schema:CreativeWork
422 https://doi.org/10.1126/science.1068327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062445812
423 rdf:type schema:CreativeWork
424 https://doi.org/10.1126/science.1082504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062447938
425 rdf:type schema:CreativeWork
426 https://doi.org/10.1126/science.275.5302.964 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062555783
427 rdf:type schema:CreativeWork
428 https://doi.org/10.1158/0008-5472.can-03-3126 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047832996
429 rdf:type schema:CreativeWork
430 https://doi.org/10.1158/0008-5472.can-03-3391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027847659
431 rdf:type schema:CreativeWork
432 https://doi.org/10.1158/0008-5472.can-04-0265 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004576540
433 rdf:type schema:CreativeWork
434 https://doi.org/10.1158/0008-5472.can-04-0580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041229486
435 rdf:type schema:CreativeWork
436 https://doi.org/10.1159/000071373 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050628817
437 rdf:type schema:CreativeWork
438 https://doi.org/10.1172/jci5028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022103776
439 rdf:type schema:CreativeWork
440 https://doi.org/10.1172/jci8829 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036426384
441 rdf:type schema:CreativeWork
442 https://doi.org/10.1172/jci9872 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018143975
443 rdf:type schema:CreativeWork
444 https://doi.org/10.1177/107327480301000105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075241335
445 rdf:type schema:CreativeWork
446 https://doi.org/10.1182/blood-2003-01-0223 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039774871
447 rdf:type schema:CreativeWork
448 https://doi.org/10.1182/blood-2003-02-0365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045288676
449 rdf:type schema:CreativeWork
450 https://doi.org/10.1200/jco.1997.15.1.187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083031480
451 rdf:type schema:CreativeWork
452 https://doi.org/10.1200/jco.2000.18.16.2935 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074684743
453 rdf:type schema:CreativeWork
454 https://doi.org/10.1200/jco.2000.18.6.1212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074604319
455 rdf:type schema:CreativeWork
456 https://doi.org/10.1200/jco.2001.19.12.3091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074835662
457 rdf:type schema:CreativeWork
458 https://doi.org/10.1200/jco.2001.19.4.1195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074754844
459 rdf:type schema:CreativeWork
460 https://doi.org/10.1200/jco.2002.20.17.3574 schema:sameAs https://app.dimensions.ai/details/publication/pub.1075115180
461 rdf:type schema:CreativeWork
462 https://doi.org/10.1200/jco.2003.02.061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203391
463 rdf:type schema:CreativeWork
464 https://doi.org/10.1200/jco.2003.08.092 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203798
465 rdf:type schema:CreativeWork
466 https://doi.org/10.1200/jco.2003.09.081 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203847
467 rdf:type schema:CreativeWork
468 https://doi.org/10.1200/jco.2003.10.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064203892
469 rdf:type schema:CreativeWork
470 https://doi.org/10.1200/jco.2003.12.068 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064204008
471 rdf:type schema:CreativeWork
472 https://doi.org/10.1200/jco.2004.07.060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052822724
473 rdf:type schema:CreativeWork
474 https://doi.org/10.1200/jco.2004.22.14_suppl.610 schema:sameAs https://app.dimensions.ai/details/publication/pub.1084615035
475 rdf:type schema:CreativeWork
476 https://doi.org/10.1542/peds.103.6.1145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067819985
477 rdf:type schema:CreativeWork
478 https://doi.org/10.2174/1389450013348597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069180035
479 rdf:type schema:CreativeWork
480 https://doi.org/10.3892/or.10.5.1213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071528893
481 rdf:type schema:CreativeWork
482 https://www.grid.ac/institutes/grid.413104.3 schema:alternateName Sunnybrook Health Science Centre
483 schema:name Molecular and Cellular Biology Research, Sunnybrook and Women's College Health Sciences Centre, S-217, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. RSKerbel@aol.com
484 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...