Extraction, purification and analysis of histones View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-06

AUTHORS

David Shechter, Holger L Dormann, C David Allis, Sandra B Hake

ABSTRACT

Histone proteins are the major protein components of chromatin, the physiologically relevant form of the genome (or epigenome) in all eukaryotic cells. Chromatin is the substrate of many biological processes, such as gene regulation and transcription, replication, mitosis and apoptosis. Since histones are extensively post-translationally modified, the identification of these covalent marks on canonical and variant histones is crucial for the understanding of their biological significance. Many different biochemical techniques have been developed to purify and separate histone proteins. Here, we present standard protocols for acid extraction and salt extraction of histones from chromatin; separation of extracted histones by reversed-phase HPLC; analysis of histones and their specific post-translational modification profiles by acid urea (AU) gel electrophoresis and the additional separation of non-canonical histone variants by triton AU(TAU) and 2D TAU electrophoresis; and immunoblotting of isolated histone proteins with modification-specific antibodies. More... »

PAGES

1445-1457

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nprot.2007.202

DOI

http://dx.doi.org/10.1038/nprot.2007.202

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009324955

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17545981


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Animals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cells, Cultured", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Histones", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mammals", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Protein Conformation", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Rockefeller University", 
          "id": "https://www.grid.ac/institutes/grid.134907.8", 
          "name": [
            "The Laboratory of Chromatin Biology, The Rockefeller University, New York, NY, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shechter", 
        "givenName": "David", 
        "id": "sg:person.0735744141.13", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735744141.13"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rockefeller University", 
          "id": "https://www.grid.ac/institutes/grid.134907.8", 
          "name": [
            "The Laboratory of Chromatin Biology, The Rockefeller University, New York, NY, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dormann", 
        "givenName": "Holger L", 
        "id": "sg:person.01334057716.20", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334057716.20"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rockefeller University", 
          "id": "https://www.grid.ac/institutes/grid.134907.8", 
          "name": [
            "The Laboratory of Chromatin Biology, The Rockefeller University, New York, NY, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Allis", 
        "givenName": "C David", 
        "id": "sg:person.01044565073.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044565073.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Rockefeller University", 
          "id": "https://www.grid.ac/institutes/grid.134907.8", 
          "name": [
            "The Laboratory of Chromatin Biology, The Rockefeller University, New York, NY, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hake", 
        "givenName": "Sandra B", 
        "id": "sg:person.01100065445.62", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100065445.62"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/0003-9861(69)90042-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000306972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0091-679x(08)60583-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005778308"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0263-7855(96)00018-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005898005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/166780a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011096023", 
          "https://doi.org/10.1038/166780a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0076-6879(89)70061-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014252833"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1980.tb04762.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014712488"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(02)00386-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015369889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.51.5.786", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016789600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0610993104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022085116"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2005.03.036", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022743547"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2007.02.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022937373"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m607900200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024032120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(02)00941-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026586548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026679380", 
          "https://doi.org/10.1038/ncb1145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ncb1145", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026679380", 
          "https://doi.org/10.1038/ncb1145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0021-9673(01)90931-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034074024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.79.2.137", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034562397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.gde.2006.02.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036888936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1139/o06-085", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037773537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(66)80116-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037799158"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/171737a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040343773", 
          "https://doi.org/10.1038/171737a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00231306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043508769", 
          "https://doi.org/10.1007/bf00231306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00231306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043508769", 
          "https://doi.org/10.1007/bf00231306"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)81063-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043841651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m509266200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044257146"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0092-8674(00)00118-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046846916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1040078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048077701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj1040078", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048077701"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2006.288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053697239", 
          "https://doi.org/10.1038/nprot.2006.288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2006.288", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053697239", 
          "https://doi.org/10.1038/nprot.2006.288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00715a026", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055186252"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cb600188m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055226791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cb600188m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055226791"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/cb6002306", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055226803"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.272.5260.408", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062552793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2741/1580", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070913866"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2007-06", 
    "datePublishedReg": "2007-06-01", 
    "description": "Histone proteins are the major protein components of chromatin, the physiologically relevant form of the genome (or epigenome) in all eukaryotic cells. Chromatin is the substrate of many biological processes, such as gene regulation and transcription, replication, mitosis and apoptosis. Since histones are extensively post-translationally modified, the identification of these covalent marks on canonical and variant histones is crucial for the understanding of their biological significance. Many different biochemical techniques have been developed to purify and separate histone proteins. Here, we present standard protocols for acid extraction and salt extraction of histones from chromatin; separation of extracted histones by reversed-phase HPLC; analysis of histones and their specific post-translational modification profiles by acid urea (AU) gel electrophoresis and the additional separation of non-canonical histone variants by triton AU(TAU) and 2D TAU electrophoresis; and immunoblotting of isolated histone proteins with modification-specific antibodies.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nprot.2007.202", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1037502", 
        "issn": [
          "1754-2189", 
          "1750-2799"
        ], 
        "name": "Nature Protocols", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "2"
      }
    ], 
    "name": "Extraction, purification and analysis of histones", 
    "pagination": "1445-1457", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2c6bd04db02c93a2f1c9bc93e3569c5392413028f91932bb128772518753ae05"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "17545981"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101284307"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nprot.2007.202"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1009324955"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nprot.2007.202", 
      "https://app.dimensions.ai/details/publication/pub.1009324955"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T00:54", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8697_00000422.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/nprot.2007.202"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nprot.2007.202'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nprot.2007.202'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nprot.2007.202'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nprot.2007.202'


 

This table displays all metadata directly associated to this object as RDF triples.

208 TRIPLES      21 PREDICATES      65 URIs      26 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nprot.2007.202 schema:about N00d671cd5f8748218412c3ffd96d7f3c
2 N0ce199ada27941b8a95097132ec9e414
3 N1a1b316bccdd4a6e93e29aea2adb93b5
4 N623244b4b220479194430f186acfc835
5 N9456924606c34b25ac7e2609a9d6ed9c
6 anzsrc-for:06
7 anzsrc-for:0604
8 schema:author N4cc91442bc92483c92691895e3407341
9 schema:citation sg:pub.10.1007/bf00231306
10 sg:pub.10.1038/166780a0
11 sg:pub.10.1038/171737a0
12 sg:pub.10.1038/ncb1145
13 sg:pub.10.1038/nprot.2006.288
14 https://doi.org/10.1016/0003-9861(69)90042-3
15 https://doi.org/10.1016/0076-6879(89)70061-6
16 https://doi.org/10.1016/0263-7855(96)00018-5
17 https://doi.org/10.1016/j.cell.2005.03.036
18 https://doi.org/10.1016/j.cell.2007.02.005
19 https://doi.org/10.1016/j.gde.2006.02.015
20 https://doi.org/10.1016/s0021-9673(01)90931-8
21 https://doi.org/10.1016/s0022-2836(02)00386-8
22 https://doi.org/10.1016/s0022-2836(66)80116-x
23 https://doi.org/10.1016/s0091-679x(08)60583-x
24 https://doi.org/10.1016/s0092-8674(00)00118-5
25 https://doi.org/10.1016/s0092-8674(00)81063-6
26 https://doi.org/10.1016/s0092-8674(02)00941-8
27 https://doi.org/10.1021/bi00715a026
28 https://doi.org/10.1021/cb600188m
29 https://doi.org/10.1021/cb6002306
30 https://doi.org/10.1042/bj1040078
31 https://doi.org/10.1073/pnas.0610993104
32 https://doi.org/10.1073/pnas.51.5.786
33 https://doi.org/10.1074/jbc.m509266200
34 https://doi.org/10.1074/jbc.m607900200
35 https://doi.org/10.1084/jem.79.2.137
36 https://doi.org/10.1111/j.1432-1033.1980.tb04762.x
37 https://doi.org/10.1126/science.272.5260.408
38 https://doi.org/10.1139/o06-085
39 https://doi.org/10.2741/1580
40 schema:datePublished 2007-06
41 schema:datePublishedReg 2007-06-01
42 schema:description Histone proteins are the major protein components of chromatin, the physiologically relevant form of the genome (or epigenome) in all eukaryotic cells. Chromatin is the substrate of many biological processes, such as gene regulation and transcription, replication, mitosis and apoptosis. Since histones are extensively post-translationally modified, the identification of these covalent marks on canonical and variant histones is crucial for the understanding of their biological significance. Many different biochemical techniques have been developed to purify and separate histone proteins. Here, we present standard protocols for acid extraction and salt extraction of histones from chromatin; separation of extracted histones by reversed-phase HPLC; analysis of histones and their specific post-translational modification profiles by acid urea (AU) gel electrophoresis and the additional separation of non-canonical histone variants by triton AU(TAU) and 2D TAU electrophoresis; and immunoblotting of isolated histone proteins with modification-specific antibodies.
43 schema:genre research_article
44 schema:inLanguage en
45 schema:isAccessibleForFree false
46 schema:isPartOf N0332355e3cc6414c9feedfa7eec52e51
47 N7b1b1517213a4b89b02cc166e3a07614
48 sg:journal.1037502
49 schema:name Extraction, purification and analysis of histones
50 schema:pagination 1445-1457
51 schema:productId N007314999af441dd950b12c04c882c60
52 N58786733bc4c4b719be5e3e013a19979
53 N591a257851924a3bae701d9b0d93edb4
54 N7aea567b9b1a420180893175afaf00e5
55 N85a98ab004a44cbf9462ee73f6ce32ab
56 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009324955
57 https://doi.org/10.1038/nprot.2007.202
58 schema:sdDatePublished 2019-04-11T00:54
59 schema:sdLicense https://scigraph.springernature.com/explorer/license/
60 schema:sdPublisher N8547946f54c14860b6dba53c4d9fa4d3
61 schema:url http://www.nature.com/articles/nprot.2007.202
62 sgo:license sg:explorer/license/
63 sgo:sdDataset articles
64 rdf:type schema:ScholarlyArticle
65 N007314999af441dd950b12c04c882c60 schema:name doi
66 schema:value 10.1038/nprot.2007.202
67 rdf:type schema:PropertyValue
68 N00d671cd5f8748218412c3ffd96d7f3c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
69 schema:name Protein Conformation
70 rdf:type schema:DefinedTerm
71 N0332355e3cc6414c9feedfa7eec52e51 schema:issueNumber 6
72 rdf:type schema:PublicationIssue
73 N0c691e715cba412fbb2d593d95e81697 rdf:first sg:person.01044565073.45
74 rdf:rest Na737f0edd34145d0ae570d33cee6eefd
75 N0ce199ada27941b8a95097132ec9e414 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
76 schema:name Mammals
77 rdf:type schema:DefinedTerm
78 N171a7a689fed40ed82089ffca801a920 rdf:first sg:person.01334057716.20
79 rdf:rest N0c691e715cba412fbb2d593d95e81697
80 N1a1b316bccdd4a6e93e29aea2adb93b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Cells, Cultured
82 rdf:type schema:DefinedTerm
83 N4cc91442bc92483c92691895e3407341 rdf:first sg:person.0735744141.13
84 rdf:rest N171a7a689fed40ed82089ffca801a920
85 N58786733bc4c4b719be5e3e013a19979 schema:name nlm_unique_id
86 schema:value 101284307
87 rdf:type schema:PropertyValue
88 N591a257851924a3bae701d9b0d93edb4 schema:name readcube_id
89 schema:value 2c6bd04db02c93a2f1c9bc93e3569c5392413028f91932bb128772518753ae05
90 rdf:type schema:PropertyValue
91 N623244b4b220479194430f186acfc835 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
92 schema:name Histones
93 rdf:type schema:DefinedTerm
94 N7aea567b9b1a420180893175afaf00e5 schema:name pubmed_id
95 schema:value 17545981
96 rdf:type schema:PropertyValue
97 N7b1b1517213a4b89b02cc166e3a07614 schema:volumeNumber 2
98 rdf:type schema:PublicationVolume
99 N8547946f54c14860b6dba53c4d9fa4d3 schema:name Springer Nature - SN SciGraph project
100 rdf:type schema:Organization
101 N85a98ab004a44cbf9462ee73f6ce32ab schema:name dimensions_id
102 schema:value pub.1009324955
103 rdf:type schema:PropertyValue
104 N9456924606c34b25ac7e2609a9d6ed9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Animals
106 rdf:type schema:DefinedTerm
107 Na737f0edd34145d0ae570d33cee6eefd rdf:first sg:person.01100065445.62
108 rdf:rest rdf:nil
109 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
110 schema:name Biological Sciences
111 rdf:type schema:DefinedTerm
112 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
113 schema:name Genetics
114 rdf:type schema:DefinedTerm
115 sg:journal.1037502 schema:issn 1750-2799
116 1754-2189
117 schema:name Nature Protocols
118 rdf:type schema:Periodical
119 sg:person.01044565073.45 schema:affiliation https://www.grid.ac/institutes/grid.134907.8
120 schema:familyName Allis
121 schema:givenName C David
122 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01044565073.45
123 rdf:type schema:Person
124 sg:person.01100065445.62 schema:affiliation https://www.grid.ac/institutes/grid.134907.8
125 schema:familyName Hake
126 schema:givenName Sandra B
127 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01100065445.62
128 rdf:type schema:Person
129 sg:person.01334057716.20 schema:affiliation https://www.grid.ac/institutes/grid.134907.8
130 schema:familyName Dormann
131 schema:givenName Holger L
132 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01334057716.20
133 rdf:type schema:Person
134 sg:person.0735744141.13 schema:affiliation https://www.grid.ac/institutes/grid.134907.8
135 schema:familyName Shechter
136 schema:givenName David
137 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735744141.13
138 rdf:type schema:Person
139 sg:pub.10.1007/bf00231306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043508769
140 https://doi.org/10.1007/bf00231306
141 rdf:type schema:CreativeWork
142 sg:pub.10.1038/166780a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011096023
143 https://doi.org/10.1038/166780a0
144 rdf:type schema:CreativeWork
145 sg:pub.10.1038/171737a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040343773
146 https://doi.org/10.1038/171737a0
147 rdf:type schema:CreativeWork
148 sg:pub.10.1038/ncb1145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026679380
149 https://doi.org/10.1038/ncb1145
150 rdf:type schema:CreativeWork
151 sg:pub.10.1038/nprot.2006.288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053697239
152 https://doi.org/10.1038/nprot.2006.288
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1016/0003-9861(69)90042-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000306972
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1016/0076-6879(89)70061-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014252833
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1016/0263-7855(96)00018-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005898005
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1016/j.cell.2005.03.036 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022743547
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1016/j.cell.2007.02.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022937373
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1016/j.gde.2006.02.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036888936
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1016/s0021-9673(01)90931-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034074024
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1016/s0022-2836(02)00386-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015369889
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1016/s0022-2836(66)80116-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1037799158
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1016/s0091-679x(08)60583-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1005778308
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1016/s0092-8674(00)00118-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046846916
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1016/s0092-8674(00)81063-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043841651
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1016/s0092-8674(02)00941-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026586548
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1021/bi00715a026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055186252
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1021/cb600188m schema:sameAs https://app.dimensions.ai/details/publication/pub.1055226791
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1021/cb6002306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055226803
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1042/bj1040078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048077701
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1073/pnas.0610993104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022085116
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1073/pnas.51.5.786 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016789600
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1074/jbc.m509266200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044257146
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1074/jbc.m607900200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024032120
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1084/jem.79.2.137 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034562397
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1111/j.1432-1033.1980.tb04762.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014712488
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1126/science.272.5260.408 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062552793
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1139/o06-085 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037773537
203 rdf:type schema:CreativeWork
204 https://doi.org/10.2741/1580 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070913866
205 rdf:type schema:CreativeWork
206 https://www.grid.ac/institutes/grid.134907.8 schema:alternateName Rockefeller University
207 schema:name The Laboratory of Chromatin Biology, The Rockefeller University, New York, NY, USA.
208 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...