Nanocarriers as an emerging platform for cancer therapy View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-12

AUTHORS

Dan Peer, Jeffrey M. Karp, Seungpyo Hong, Omid C. Farokhzad, Rimona Margalit, Robert Langer

ABSTRACT

Nanotechnology has the potential to revolutionize cancer diagnosis and therapy. Advances in protein engineering and materials science have contributed to novel nanoscale targeting approaches that may bring new hope to cancer patients. Several therapeutic nanocarriers have been approved for clinical use. However, to date, there are only a few clinically approved nanocarriers that incorporate molecules to selectively bind and target cancer cells. This review examines some of the approved formulations and discusses the challenges in translating basic research to the clinic. We detail the arsenal of nanocarriers and molecules available for selective tumour targeting, and emphasize the challenges in cancer treatment. More... »

PAGES

751-760

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  • Journal

    TITLE

    Nature Nanotechnology

    ISSUE

    12

    VOLUME

    2

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nnano.2007.387

    DOI

    http://dx.doi.org/10.1038/nnano.2007.387

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034703917

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/18654426


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