The drive to eat: comparisons and distinctions between mechanisms of food reward and drug addiction View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-10

AUTHORS

Ralph J DiLeone, Jane R Taylor, Marina R Picciotto

ABSTRACT

The growing rates of obesity have prompted comparisons between the uncontrolled intake of food and drugs; however, an evaluation of the equivalence of food- and drug-related behaviors requires a thorough understanding of the underlying neural circuits driving each behavior. Although it has been attractive to borrow neurobiological concepts from addiction to explore compulsive food seeking, a more integrated model is needed to understand how food and drugs differ in their ability to drive behavior. In this Review, we will examine the commonalities and differences in the systems-level and behavioral responses to food and to drugs of abuse, with the goal of identifying areas of research that would address gaps in our understanding and ultimately identify new treatments for obesity or drug addiction. More... »

PAGES

1330

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nn.3202

DOI

http://dx.doi.org/10.1038/nn.3202

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1028430968

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23007187


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