Ontology type: schema:ScholarlyArticle Open Access: True
2011-12-18
AUTHORSJun B Ding, Won-Jong Oh, Bernardo L Sabatini, Chenghua Gu
ABSTRACTIn the striatum, direct pathway and indirect pathway medium spiny neurons (MSNs) receive both cortical and thalamic projections in an intermingled fashion. This study shows that a known axonal repulsive cue system—semaphorin 3E and its receptor Plexin-D1—acts as a determinant of thalamostriatal synapse development, specifically for direct pathway MSNs where presynaptic axons express the ligand and the receptor signals in the postsynaptic MSN target. More... »
PAGES215-223
http://scigraph.springernature.com/pub.10.1038/nn.3003
DOIhttp://dx.doi.org/10.1038/nn.3003
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PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/22179111
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