Sartobind STIC<sup>®</sup> salt-tolerant membrane chromatography View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2010-12

AUTHORS

Stefan Fischer-Frühholz, Dave Zhou, Miyako Hirai

ABSTRACT

Sartobind membranes with Q chemistry are proven and robust platforms and have been validated in hundreds of processes. Sartobind STIC with primary amine ligand overcomes the limitation of Q chemistry and can bind contaminants at high conductivities. Higher binding capacity for impurities in high salt provides more robustness in mAb production. The salt-tolerant anion exchanger can reduce plant bottlenecks, buffer consumption and buffer tank investments. More... »

PAGES

1026

Journal

TITLE

Nature Methods

ISSUE

12

VOLUME

7

Author Affiliations

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nmeth.f.319

DOI

http://dx.doi.org/10.1038/nmeth.f.319

DIMENSIONS

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