Towards error-free profiling of immune repertoires View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2014-06

AUTHORS

Mikhail Shugay, Olga V Britanova, Ekaterina M Merzlyak, Maria A Turchaninova, Ilgar Z Mamedov, Timur R Tuganbaev, Dmitriy A Bolotin, Dmitry B Staroverov, Ekaterina V Putintseva, Karla Plevova, Carsten Linnemann, Dmitriy Shagin, Sarka Pospisilova, Sergey Lukyanov, Ton N Schumacher, Dmitriy M Chudakov

ABSTRACT

Deep profiling of antibody and T cell-receptor repertoires by means of high-throughput sequencing has become an attractive approach for adaptive immunity studies, but its power is substantially compromised by the accumulation of PCR and sequencing errors. Here we report MIGEC (molecular identifier groups-based error correction), a strategy for high-throughput sequencing data analysis. MIGEC allows for nearly absolute error correction while fully preserving the natural diversity of complex immune repertoires. More... »

PAGES

653-655

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nmeth.2960

DOI

http://dx.doi.org/10.1038/nmeth.2960

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1016186405

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24793455


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Immunology", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Medical and Health Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Fingerprinting", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "High-Throughput Nucleotide Sequencing", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymerase Chain Reaction", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Receptors, Antigen, T-Cell", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Research Design", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Pirogov Russian National Research Medical University", 
          "id": "https://www.grid.ac/institutes/grid.78028.35", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.", 
            "Pirogov Russian National Research Medical University, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shugay", 
        "givenName": "Mikhail", 
        "id": "sg:person.0725616014.35", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725616014.35"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Britanova", 
        "givenName": "Olga V", 
        "id": "sg:person.01021011024.01", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021011024.01"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Merzlyak", 
        "givenName": "Ekaterina M", 
        "id": "sg:person.01076232460.29", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076232460.29"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Turchaninova", 
        "givenName": "Maria A", 
        "id": "sg:person.01025153237.27", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025153237.27"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central European Institute of Technology \u2013 Masaryk University", 
          "id": "https://www.grid.ac/institutes/grid.497421.d", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.", 
            "Central European Institute of Technology, Masaryk University, Brno, Czech Republic."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mamedov", 
        "givenName": "Ilgar Z", 
        "id": "sg:person.016371611320.45", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016371611320.45"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tuganbaev", 
        "givenName": "Timur R", 
        "id": "sg:person.0705053361.44", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705053361.44"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Bolotin", 
        "givenName": "Dmitriy A", 
        "id": "sg:person.01260574260.58", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260574260.58"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Staroverov", 
        "givenName": "Dmitry B", 
        "id": "sg:person.0634471444.78", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634471444.78"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Russian Academy of Sciences", 
          "id": "https://www.grid.ac/institutes/grid.4886.2", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Putintseva", 
        "givenName": "Ekaterina V", 
        "id": "sg:person.01255205715.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255205715.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central European Institute of Technology \u2013 Masaryk University", 
          "id": "https://www.grid.ac/institutes/grid.497421.d", 
          "name": [
            "Central European Institute of Technology, Masaryk University, Brno, Czech Republic."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Plevova", 
        "givenName": "Karla", 
        "id": "sg:person.01304404373.79", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304404373.79"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antoni van Leeuwenhoek Hospital", 
          "id": "https://www.grid.ac/institutes/grid.430814.a", 
          "name": [
            "Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Linnemann", 
        "givenName": "Carsten", 
        "id": "sg:person.0622700202.87", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622700202.87"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pirogov Russian National Research Medical University", 
          "id": "https://www.grid.ac/institutes/grid.78028.35", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.", 
            "Pirogov Russian National Research Medical University, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Shagin", 
        "givenName": "Dmitriy", 
        "id": "sg:person.01022212007.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022212007.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central European Institute of Technology \u2013 Masaryk University", 
          "id": "https://www.grid.ac/institutes/grid.497421.d", 
          "name": [
            "Central European Institute of Technology, Masaryk University, Brno, Czech Republic."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pospisilova", 
        "givenName": "Sarka", 
        "id": "sg:person.015775473660.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015775473660.67"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Pirogov Russian National Research Medical University", 
          "id": "https://www.grid.ac/institutes/grid.78028.35", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.", 
            "Pirogov Russian National Research Medical University, Moscow, Russia."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lukyanov", 
        "givenName": "Sergey", 
        "id": "sg:person.012130214117.61", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012130214117.61"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Antoni van Leeuwenhoek Hospital", 
          "id": "https://www.grid.ac/institutes/grid.430814.a", 
          "name": [
            "Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Schumacher", 
        "givenName": "Ton N", 
        "id": "sg:person.0641002657.56", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641002657.56"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Central European Institute of Technology \u2013 Masaryk University", 
          "id": "https://www.grid.ac/institutes/grid.497421.d", 
          "name": [
            "Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.", 
            "Pirogov Russian National Research Medical University, Moscow, Russia.", 
            "Central European Institute of Technology, Masaryk University, Brno, Czech Republic."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Chudakov", 
        "givenName": "Dmitriy M", 
        "id": "sg:person.014526463460.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014526463460.22"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1186/1471-2164-12-106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004430249", 
          "https://doi.org/10.1186/1471-2164-12-106"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.168.6.3099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005774397"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkt382", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006394353"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3389/fimmu.2013.00463", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008153548"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.201242517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012447543"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2009-04-217604", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014830407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0801523105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015533038"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1301384", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015947992"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.1778", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017388763", 
          "https://doi.org/10.1038/nmeth.1778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nmeth.2555", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019756199", 
          "https://doi.org/10.1038/nmeth.2555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1105422108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025253093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg3542", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029194837", 
          "https://doi.org/10.1038/nrg3542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/emmm.201100129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029196542"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/bmt.2012.44", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032312344", 
          "https://doi.org/10.1038/bmt.2012.44"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.115428.110", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038599692"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0909775106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042221024"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1118357109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042605691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.154815.113", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045880766"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1302064", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046009553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4049/jimmunol.1003898", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046254651"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.1002889", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046768406"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0070388", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049244655"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gkn316", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051706958"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2014-06", 
    "datePublishedReg": "2014-06-01", 
    "description": "Deep profiling of antibody and T cell-receptor repertoires by means of high-throughput sequencing has become an attractive approach for adaptive immunity studies, but its power is substantially compromised by the accumulation of PCR and sequencing errors. Here we report MIGEC (molecular identifier groups-based error correction), a strategy for high-throughput sequencing data analysis. MIGEC allows for nearly absolute error correction while fully preserving the natural diversity of complex immune repertoires. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/nmeth.2960", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.6752019", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5330437", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5335403", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1033763", 
        "issn": [
          "1548-7091", 
          "1548-7105"
        ], 
        "name": "Nature Methods", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "6", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "11"
      }
    ], 
    "name": "Towards error-free profiling of immune repertoires", 
    "pagination": "653-655", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "4d1ff6a990212af32509607ebf717b33214d525468e6e7a5a1ed806aec00480d"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24793455"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "101215604"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/nmeth.2960"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1016186405"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/nmeth.2960", 
      "https://app.dimensions.ai/details/publication/pub.1016186405"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T18:56", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8678_00000424.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/articles/nmeth.2960"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nmeth.2960'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nmeth.2960'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nmeth.2960'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nmeth.2960'


 

This table displays all metadata directly associated to this object as RDF triples.

286 TRIPLES      21 PREDICATES      57 URIs      26 LITERALS      14 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/nmeth.2960 schema:about N0dd2f2a9e5144741a0cb9fbede3aa3ea
2 N3b0ee43a50f941d49ae097b6e36a6558
3 N88fa5513606f4fd7a03ae61c2b1e27f4
4 N8e10c09381ca44f5879cdc7b7674fc58
5 N989b2e26fa354bb3b425775c560e9ae7
6 anzsrc-for:11
7 anzsrc-for:1107
8 schema:author N2edfb6928d604effa2dcf3d412944722
9 schema:citation sg:pub.10.1038/bmt.2012.44
10 sg:pub.10.1038/nmeth.1778
11 sg:pub.10.1038/nmeth.2555
12 sg:pub.10.1038/nrg3542
13 sg:pub.10.1186/1471-2164-12-106
14 https://doi.org/10.1002/eji.201242517
15 https://doi.org/10.1002/emmm.201100129
16 https://doi.org/10.1073/pnas.0801523105
17 https://doi.org/10.1073/pnas.0909775106
18 https://doi.org/10.1073/pnas.1105422108
19 https://doi.org/10.1073/pnas.1118357109
20 https://doi.org/10.1093/nar/gkn316
21 https://doi.org/10.1093/nar/gkt382
22 https://doi.org/10.1101/gr.115428.110
23 https://doi.org/10.1101/gr.154815.113
24 https://doi.org/10.1182/blood-2009-04-217604
25 https://doi.org/10.1371/journal.pone.0070388
26 https://doi.org/10.1371/journal.ppat.1002889
27 https://doi.org/10.3389/fimmu.2013.00463
28 https://doi.org/10.4049/jimmunol.1003898
29 https://doi.org/10.4049/jimmunol.1301384
30 https://doi.org/10.4049/jimmunol.1302064
31 https://doi.org/10.4049/jimmunol.168.6.3099
32 schema:datePublished 2014-06
33 schema:datePublishedReg 2014-06-01
34 schema:description Deep profiling of antibody and T cell-receptor repertoires by means of high-throughput sequencing has become an attractive approach for adaptive immunity studies, but its power is substantially compromised by the accumulation of PCR and sequencing errors. Here we report MIGEC (molecular identifier groups-based error correction), a strategy for high-throughput sequencing data analysis. MIGEC allows for nearly absolute error correction while fully preserving the natural diversity of complex immune repertoires.
35 schema:genre research_article
36 schema:inLanguage en
37 schema:isAccessibleForFree false
38 schema:isPartOf Nf2ba0128102d4f75ad51546bb2b2b5f1
39 Nfc21d092e2084b559ab8752532a06239
40 sg:journal.1033763
41 schema:name Towards error-free profiling of immune repertoires
42 schema:pagination 653-655
43 schema:productId N02f2c7382dd240b5af3207a90b167ef3
44 N452a8b756d60451abbe8a3d23fdf7549
45 N6438275c3da846f280ca3e5c870edcf9
46 N6cd008dabf9b4cc3a290036bd5c604fa
47 Nd05aa733bf544681869966bdfe98ed83
48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016186405
49 https://doi.org/10.1038/nmeth.2960
50 schema:sdDatePublished 2019-04-10T18:56
51 schema:sdLicense https://scigraph.springernature.com/explorer/license/
52 schema:sdPublisher N8f923c8080b148b7a83aa8738c267d1b
53 schema:url http://www.nature.com/articles/nmeth.2960
54 sgo:license sg:explorer/license/
55 sgo:sdDataset articles
56 rdf:type schema:ScholarlyArticle
57 N02f2c7382dd240b5af3207a90b167ef3 schema:name pubmed_id
58 schema:value 24793455
59 rdf:type schema:PropertyValue
60 N0dd2f2a9e5144741a0cb9fbede3aa3ea schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
61 schema:name Receptors, Antigen, T-Cell
62 rdf:type schema:DefinedTerm
63 N0f544f27fd794a76bf9e947a592ebde2 rdf:first sg:person.012130214117.61
64 rdf:rest N26b32a3eda3040048647606f665b6877
65 N0f84b2c363fb4846a1fab9057180f27a rdf:first sg:person.01022212007.37
66 rdf:rest N7b96be6d5dcb41f3b1dbd88a260acbfc
67 N191cbe3c09a44c7c963a72c26f840ed9 rdf:first sg:person.0634471444.78
68 rdf:rest N4560d0b5aee84ebcbfb37dc68a6c21fd
69 N1b8635fb2dc94a49a5e70c1353d7c817 rdf:first sg:person.01304404373.79
70 rdf:rest N62221d5911584060b39f8af6c2fd8e99
71 N26b32a3eda3040048647606f665b6877 rdf:first sg:person.0641002657.56
72 rdf:rest N9fa665ad9cd441cfac9bc4bd0958d970
73 N2edfb6928d604effa2dcf3d412944722 rdf:first sg:person.0725616014.35
74 rdf:rest N324f0094ad3646b29a555a0730c076e6
75 N324f0094ad3646b29a555a0730c076e6 rdf:first sg:person.01021011024.01
76 rdf:rest Nb8953fbf02094231b2c43d4ebf41aaa7
77 N3b0ee43a50f941d49ae097b6e36a6558 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
78 schema:name Research Design
79 rdf:type schema:DefinedTerm
80 N452a8b756d60451abbe8a3d23fdf7549 schema:name nlm_unique_id
81 schema:value 101215604
82 rdf:type schema:PropertyValue
83 N4560d0b5aee84ebcbfb37dc68a6c21fd rdf:first sg:person.01255205715.19
84 rdf:rest N1b8635fb2dc94a49a5e70c1353d7c817
85 N58f046ac32834bf386bffad6802eaa85 rdf:first sg:person.01025153237.27
86 rdf:rest N7974706ca2314a7bbe65ed857a943eba
87 N62221d5911584060b39f8af6c2fd8e99 rdf:first sg:person.0622700202.87
88 rdf:rest N0f84b2c363fb4846a1fab9057180f27a
89 N6438275c3da846f280ca3e5c870edcf9 schema:name dimensions_id
90 schema:value pub.1016186405
91 rdf:type schema:PropertyValue
92 N6cd008dabf9b4cc3a290036bd5c604fa schema:name doi
93 schema:value 10.1038/nmeth.2960
94 rdf:type schema:PropertyValue
95 N7974706ca2314a7bbe65ed857a943eba rdf:first sg:person.016371611320.45
96 rdf:rest N9e15be7d67034dc3943779a58e6c0d32
97 N7b96be6d5dcb41f3b1dbd88a260acbfc rdf:first sg:person.015775473660.67
98 rdf:rest N0f544f27fd794a76bf9e947a592ebde2
99 N88fa5513606f4fd7a03ae61c2b1e27f4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
100 schema:name Polymerase Chain Reaction
101 rdf:type schema:DefinedTerm
102 N8e10c09381ca44f5879cdc7b7674fc58 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
103 schema:name High-Throughput Nucleotide Sequencing
104 rdf:type schema:DefinedTerm
105 N8f923c8080b148b7a83aa8738c267d1b schema:name Springer Nature - SN SciGraph project
106 rdf:type schema:Organization
107 N989b2e26fa354bb3b425775c560e9ae7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
108 schema:name DNA Fingerprinting
109 rdf:type schema:DefinedTerm
110 N9e15be7d67034dc3943779a58e6c0d32 rdf:first sg:person.0705053361.44
111 rdf:rest Nca9d3adb1f7741dd98db095bea2b6cbc
112 N9fa665ad9cd441cfac9bc4bd0958d970 rdf:first sg:person.014526463460.22
113 rdf:rest rdf:nil
114 Nb8953fbf02094231b2c43d4ebf41aaa7 rdf:first sg:person.01076232460.29
115 rdf:rest N58f046ac32834bf386bffad6802eaa85
116 Nca9d3adb1f7741dd98db095bea2b6cbc rdf:first sg:person.01260574260.58
117 rdf:rest N191cbe3c09a44c7c963a72c26f840ed9
118 Nd05aa733bf544681869966bdfe98ed83 schema:name readcube_id
119 schema:value 4d1ff6a990212af32509607ebf717b33214d525468e6e7a5a1ed806aec00480d
120 rdf:type schema:PropertyValue
121 Nf2ba0128102d4f75ad51546bb2b2b5f1 schema:volumeNumber 11
122 rdf:type schema:PublicationVolume
123 Nfc21d092e2084b559ab8752532a06239 schema:issueNumber 6
124 rdf:type schema:PublicationIssue
125 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
126 schema:name Medical and Health Sciences
127 rdf:type schema:DefinedTerm
128 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
129 schema:name Immunology
130 rdf:type schema:DefinedTerm
131 sg:grant.5330437 http://pending.schema.org/fundedItem sg:pub.10.1038/nmeth.2960
132 rdf:type schema:MonetaryGrant
133 sg:grant.5335403 http://pending.schema.org/fundedItem sg:pub.10.1038/nmeth.2960
134 rdf:type schema:MonetaryGrant
135 sg:grant.6752019 http://pending.schema.org/fundedItem sg:pub.10.1038/nmeth.2960
136 rdf:type schema:MonetaryGrant
137 sg:journal.1033763 schema:issn 1548-7091
138 1548-7105
139 schema:name Nature Methods
140 rdf:type schema:Periodical
141 sg:person.01021011024.01 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
142 schema:familyName Britanova
143 schema:givenName Olga V
144 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021011024.01
145 rdf:type schema:Person
146 sg:person.01022212007.37 schema:affiliation https://www.grid.ac/institutes/grid.78028.35
147 schema:familyName Shagin
148 schema:givenName Dmitriy
149 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01022212007.37
150 rdf:type schema:Person
151 sg:person.01025153237.27 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
152 schema:familyName Turchaninova
153 schema:givenName Maria A
154 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025153237.27
155 rdf:type schema:Person
156 sg:person.01076232460.29 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
157 schema:familyName Merzlyak
158 schema:givenName Ekaterina M
159 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01076232460.29
160 rdf:type schema:Person
161 sg:person.012130214117.61 schema:affiliation https://www.grid.ac/institutes/grid.78028.35
162 schema:familyName Lukyanov
163 schema:givenName Sergey
164 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012130214117.61
165 rdf:type schema:Person
166 sg:person.01255205715.19 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
167 schema:familyName Putintseva
168 schema:givenName Ekaterina V
169 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255205715.19
170 rdf:type schema:Person
171 sg:person.01260574260.58 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
172 schema:familyName Bolotin
173 schema:givenName Dmitriy A
174 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01260574260.58
175 rdf:type schema:Person
176 sg:person.01304404373.79 schema:affiliation https://www.grid.ac/institutes/grid.497421.d
177 schema:familyName Plevova
178 schema:givenName Karla
179 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304404373.79
180 rdf:type schema:Person
181 sg:person.014526463460.22 schema:affiliation https://www.grid.ac/institutes/grid.497421.d
182 schema:familyName Chudakov
183 schema:givenName Dmitriy M
184 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014526463460.22
185 rdf:type schema:Person
186 sg:person.015775473660.67 schema:affiliation https://www.grid.ac/institutes/grid.497421.d
187 schema:familyName Pospisilova
188 schema:givenName Sarka
189 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015775473660.67
190 rdf:type schema:Person
191 sg:person.016371611320.45 schema:affiliation https://www.grid.ac/institutes/grid.497421.d
192 schema:familyName Mamedov
193 schema:givenName Ilgar Z
194 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016371611320.45
195 rdf:type schema:Person
196 sg:person.0622700202.87 schema:affiliation https://www.grid.ac/institutes/grid.430814.a
197 schema:familyName Linnemann
198 schema:givenName Carsten
199 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0622700202.87
200 rdf:type schema:Person
201 sg:person.0634471444.78 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
202 schema:familyName Staroverov
203 schema:givenName Dmitry B
204 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0634471444.78
205 rdf:type schema:Person
206 sg:person.0641002657.56 schema:affiliation https://www.grid.ac/institutes/grid.430814.a
207 schema:familyName Schumacher
208 schema:givenName Ton N
209 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641002657.56
210 rdf:type schema:Person
211 sg:person.0705053361.44 schema:affiliation https://www.grid.ac/institutes/grid.4886.2
212 schema:familyName Tuganbaev
213 schema:givenName Timur R
214 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0705053361.44
215 rdf:type schema:Person
216 sg:person.0725616014.35 schema:affiliation https://www.grid.ac/institutes/grid.78028.35
217 schema:familyName Shugay
218 schema:givenName Mikhail
219 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0725616014.35
220 rdf:type schema:Person
221 sg:pub.10.1038/bmt.2012.44 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032312344
222 https://doi.org/10.1038/bmt.2012.44
223 rdf:type schema:CreativeWork
224 sg:pub.10.1038/nmeth.1778 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017388763
225 https://doi.org/10.1038/nmeth.1778
226 rdf:type schema:CreativeWork
227 sg:pub.10.1038/nmeth.2555 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019756199
228 https://doi.org/10.1038/nmeth.2555
229 rdf:type schema:CreativeWork
230 sg:pub.10.1038/nrg3542 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029194837
231 https://doi.org/10.1038/nrg3542
232 rdf:type schema:CreativeWork
233 sg:pub.10.1186/1471-2164-12-106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004430249
234 https://doi.org/10.1186/1471-2164-12-106
235 rdf:type schema:CreativeWork
236 https://doi.org/10.1002/eji.201242517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012447543
237 rdf:type schema:CreativeWork
238 https://doi.org/10.1002/emmm.201100129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029196542
239 rdf:type schema:CreativeWork
240 https://doi.org/10.1073/pnas.0801523105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015533038
241 rdf:type schema:CreativeWork
242 https://doi.org/10.1073/pnas.0909775106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042221024
243 rdf:type schema:CreativeWork
244 https://doi.org/10.1073/pnas.1105422108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025253093
245 rdf:type schema:CreativeWork
246 https://doi.org/10.1073/pnas.1118357109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042605691
247 rdf:type schema:CreativeWork
248 https://doi.org/10.1093/nar/gkn316 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051706958
249 rdf:type schema:CreativeWork
250 https://doi.org/10.1093/nar/gkt382 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006394353
251 rdf:type schema:CreativeWork
252 https://doi.org/10.1101/gr.115428.110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038599692
253 rdf:type schema:CreativeWork
254 https://doi.org/10.1101/gr.154815.113 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045880766
255 rdf:type schema:CreativeWork
256 https://doi.org/10.1182/blood-2009-04-217604 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014830407
257 rdf:type schema:CreativeWork
258 https://doi.org/10.1371/journal.pone.0070388 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049244655
259 rdf:type schema:CreativeWork
260 https://doi.org/10.1371/journal.ppat.1002889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046768406
261 rdf:type schema:CreativeWork
262 https://doi.org/10.3389/fimmu.2013.00463 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008153548
263 rdf:type schema:CreativeWork
264 https://doi.org/10.4049/jimmunol.1003898 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046254651
265 rdf:type schema:CreativeWork
266 https://doi.org/10.4049/jimmunol.1301384 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015947992
267 rdf:type schema:CreativeWork
268 https://doi.org/10.4049/jimmunol.1302064 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046009553
269 rdf:type schema:CreativeWork
270 https://doi.org/10.4049/jimmunol.168.6.3099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005774397
271 rdf:type schema:CreativeWork
272 https://www.grid.ac/institutes/grid.430814.a schema:alternateName Antoni van Leeuwenhoek Hospital
273 schema:name Division of Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
274 rdf:type schema:Organization
275 https://www.grid.ac/institutes/grid.4886.2 schema:alternateName Russian Academy of Sciences
276 schema:name Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.
277 rdf:type schema:Organization
278 https://www.grid.ac/institutes/grid.497421.d schema:alternateName Central European Institute of Technology – Masaryk University
279 schema:name Central European Institute of Technology, Masaryk University, Brno, Czech Republic.
280 Pirogov Russian National Research Medical University, Moscow, Russia.
281 Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.
282 rdf:type schema:Organization
283 https://www.grid.ac/institutes/grid.78028.35 schema:alternateName Pirogov Russian National Research Medical University
284 schema:name Pirogov Russian National Research Medical University, Moscow, Russia.
285 Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, Moscow, Russia.
286 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...