Quantifying the local resolution of cryo-EM density maps View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2014-01

AUTHORS

Alp Kucukelbir, Fred J Sigworth, Hemant D Tagare

ABSTRACT

We propose a definition of local resolution for three-dimensional electron cryo-microscopy (cryo-EM) density maps that uses local sinusoidal features. Our algorithm has no free parameters and is applicable to other imaging modalities, including tomography. By evaluating the local resolution of single-particle reconstructions and subtomogram averages for four example data sets, we report variable resolution across a 4- to 40-Å range. More... »

PAGES

63-65

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nmeth.2727

DOI

http://dx.doi.org/10.1038/nmeth.2727

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009301311

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24213166


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