High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-07-17

AUTHORS

Fuqiang Chen, Shondra M Pruett-Miller, Yuping Huang, Monika Gjoka, Katarzyna Duda, Jack Taunton, Trevor N Collingwood, Morten Frodin, Gregory D Davis

ABSTRACT

Single-stranded oligonucleotides are used as donor templates for zinc-finger nucleases to create targeted genomic deletions and mutations in mammalian cell lines.

PAGES

753-755

Journal

TITLE

Nature Methods

ISSUE

9

VOLUME

8

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nmeth.1653

    DOI

    http://dx.doi.org/10.1038/nmeth.1653

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21765410


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