A systematic library for comprehensive overexpression screens in Saccharomyces cerevisiae View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2008-03

AUTHORS

Grace Marie Jones, Jim Stalker, Sean Humphray, Anthony West, Tony Cox, Jane Rogers, Ian Dunham, Gregory Prelich

ABSTRACT

Modern genetic analysis requires the development of new resources to systematically explore gene function in vivo. Overexpression screens are a powerful method to investigate genetic pathways, but the goal of routine and comprehensive overexpression screens has been hampered by the lack of systematic libraries. Here we describe the construction of a systematic collection of the Saccharomyces cerevisiae genome in a high-copy vector and its validation in two overexpression screens. More... »

PAGES

239-241

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nmeth.1181

DOI

http://dx.doi.org/10.1038/nmeth.1181

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1024273311

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18246075


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