Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-11

AUTHORS

Sandip Ray, Markus Britschgi, Charles Herbert, Yoshiko Takeda-Uchimura, Adam Boxer, Kaj Blennow, Leah F Friedman, Douglas R Galasko, Marek Jutel, Anna Karydas, Jeffrey A Kaye, Jerzy Leszek, Bruce L Miller, Lennart Minthon, Joseph F Quinn, Gil D Rabinovici, William H Robinson, Marwan N Sabbagh, Yuen T So, D Larry Sparks, Massimo Tabaton, Jared Tinklenberg, Jerome A Yesavage, Robert Tibshirani, Tony Wyss-Coray

ABSTRACT

A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 signaling proteins in blood plasma that can be used to classify blinded samples from Alzheimer's and control subjects with close to 90% accuracy and to identify patients who had mild cognitive impairment that progressed to Alzheimer's disease 2-6 years later. Biological analysis of the 18 proteins points to systemic dysregulation of hematopoiesis, immune responses, apoptosis and neuronal support in presymptomatic Alzheimer's disease. More... »

PAGES

1359-1362

References to SciGraph publications

  • 2004-04-05. Cytokine Protein Arrays in PROTEIN ARRAYS
  • 2004-06. Elaborate interactions between the immune and nervous systems in NATURE IMMUNOLOGY
  • Journal

    TITLE

    Nature Medicine

    ISSUE

    11

    VOLUME

    13

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nm1653

    DOI

    http://dx.doi.org/10.1038/nm1653

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053583368

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/17934472


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biochemistry and Cell Biology", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Alzheimer Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Biomarkers", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cognition Disorders", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Intercellular Signaling Peptides and Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phenotype", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Predictive Value of Tests", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "name": [
                "Satoris, Inc., 2686 Middlefield Road, Suite E, Redwood City, California 94063, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ray", 
            "givenName": "Sandip", 
            "id": "sg:person.01154200405.63", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154200405.63"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Britschgi", 
            "givenName": "Markus", 
            "id": "sg:person.01265567037.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265567037.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Satoris, Inc., 2686 Middlefield Road, Suite E, Redwood City, California 94063, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Herbert", 
            "givenName": "Charles", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Takeda-Uchimura", 
            "givenName": "Yoshiko", 
            "id": "sg:person.01307235400.95", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307235400.95"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boxer", 
            "givenName": "Adam", 
            "id": "sg:person.0652607533.78", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652607533.78"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Institute of Clinical Neuroscience, Department of Experimental Neuroscience, Sahlgrenska University Hospital, University of G\u00f6teborg, Bl\u00e5 str\u00e5ket 15, 431 80 M\u00f6lndal, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Blennow", 
            "givenName": "Kaj", 
            "id": "sg:person.07606016437.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07606016437.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5550, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Friedman", 
            "givenName": "Leah F", 
            "id": "sg:person.01021076041.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021076041.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, San Diego", 
              "id": "https://www.grid.ac/institutes/grid.266100.3", 
              "name": [
                "Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive #9127, La Jolla, California 92093-9127, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Galasko", 
            "givenName": "Douglas R", 
            "id": "sg:person.014114612457.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014114612457.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wroc\u0142aw Medical University", 
              "id": "https://www.grid.ac/institutes/grid.4495.c", 
              "name": [
                "Department of Internal Medicine and Allergology, Wroclaw Medical University, Traugutta 57, 50-417 Wroclaw, Poland."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jutel", 
            "givenName": "Marek", 
            "id": "sg:person.0673065763.63", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673065763.63"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Karydas", 
            "givenName": "Anna", 
            "id": "sg:person.01320644065.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320644065.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Oregon Health & Science University", 
              "id": "https://www.grid.ac/institutes/grid.5288.7", 
              "name": [
                "Layton Aging & Alzheimer's Disease Center, Oregon Health Sciences University, 3181 Southwest Sam Jackson Park Road, CR131, Portland, Oregon 97201-3098, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kaye", 
            "givenName": "Jeffrey A", 
            "id": "sg:person.015720613277.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015720613277.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wroc\u0142aw Medical University", 
              "id": "https://www.grid.ac/institutes/grid.4495.c", 
              "name": [
                "Department of Psychiatry, Wroclaw Medical University, Pasteura 10, 51-622 Wroclaw, Poland."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Leszek", 
            "givenName": "Jerzy", 
            "id": "sg:person.0741441174.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741441174.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Miller", 
            "givenName": "Bruce L", 
            "id": "sg:person.013136240367.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013136240367.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Clinical Memory Research Unit, Department of Clinical Sciences Malm\u00f6, Lund University, Universitetssjukhuset MAS, Ing\u00e5ng 56 plan 7, SE-205 02 Malm\u00f6, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Minthon", 
            "givenName": "Lennart", 
            "id": "sg:person.01046002560.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046002560.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Oregon Health & Science University", 
              "id": "https://www.grid.ac/institutes/grid.5288.7", 
              "name": [
                "Layton Aging & Alzheimer's Disease Center, Oregon Health Sciences University, 3181 Southwest Sam Jackson Park Road, CR131, Portland, Oregon 97201-3098, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Quinn", 
            "givenName": "Joseph F", 
            "id": "sg:person.016530504722.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016530504722.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rabinovici", 
            "givenName": "Gil D", 
            "id": "sg:person.01075403326.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075403326.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Division of Immunology and Rheumatology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5166, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Robinson", 
            "givenName": "William H", 
            "id": "sg:person.01036436624.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036436624.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Banner Sun Health Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.414208.b", 
              "name": [
                "Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, Arizona 85351, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sabbagh", 
            "givenName": "Marwan N", 
            "id": "sg:person.0707625530.62", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707625530.62"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "So", 
            "givenName": "Yuen T", 
            "id": "sg:person.01066747640.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066747640.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Banner Sun Health Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.414208.b", 
              "name": [
                "Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, Arizona 85351, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sparks", 
            "givenName": "D Larry", 
            "id": "sg:person.01023325552.26", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023325552.26"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Genoa", 
              "id": "https://www.grid.ac/institutes/grid.5606.5", 
              "name": [
                "Department of Neurosciences, Ophthalmology, and Genetics, University of Genoa, Via A. De Toni 5, 16132 Genoa, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tabaton", 
            "givenName": "Massimo", 
            "id": "sg:person.0602425313.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602425313.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5550, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tinklenberg", 
            "givenName": "Jared", 
            "id": "sg:person.01012120344.19", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012120344.19"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5550, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yesavage", 
            "givenName": "Jerome A", 
            "id": "sg:person.01340560123.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340560123.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Stanford University", 
              "id": "https://www.grid.ac/institutes/grid.168010.e", 
              "name": [
                "Department of Health Research and Policy, Stanford University School of Medicine, Stanford, 300 Pasteur Drive, California 94305-5405, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Tibshirani", 
            "givenName": "Robert", 
            "id": "sg:person.010253467037.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010253467037.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VA Palo Alto Health Care System", 
              "id": "https://www.grid.ac/institutes/grid.280747.e", 
              "name": [
                "Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA.", 
                "Geriatric Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, California 94304, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wyss-Coray", 
            "givenName": "Tony", 
            "id": "sg:person.01017510072.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017510072.56"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1073/pnas.091062498", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001631710"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neuron.2006.01.022", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006192059"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0308512100", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007985703"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1026133541", 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.082099299", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037994416"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(06)69113-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038428900"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.neurobiolaging.2006.08.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038551375"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1474-4422(06)70355-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039309033"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0610204104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042762077"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1385/1-59259-759-9:215", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046551425", 
              "https://doi.org/10.1385/1-59259-759-9:215"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0074-7742(07)82011-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048282183"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048922409", 
              "https://doi.org/10.1038/ni1078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1078", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048922409", 
              "https://doi.org/10.1038/ni1078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000137040.64252.ed", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064346292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000137040.64252.ed", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064346292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000137040.64252.ed", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064346292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/01.wnl.0000137040.64252.ed", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064346292"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.59.7.1034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064381192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.59.7.1034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064381192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1212/wnl.59.7.1034", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064381192"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/156720505774330573", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069188624"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2007-11", 
        "datePublishedReg": "2007-11-01", 
        "description": "A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 signaling proteins in blood plasma that can be used to classify blinded samples from Alzheimer's and control subjects with close to 90% accuracy and to identify patients who had mild cognitive impairment that progressed to Alzheimer's disease 2-6 years later. Biological analysis of the 18 proteins points to systemic dysregulation of hematopoiesis, immune responses, apoptosis and neuronal support in presymptomatic Alzheimer's disease.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/nm1653", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": false, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2438583", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2440005", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2447294", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1113716", 
            "issn": [
              "1078-8956", 
              "1546-170X"
            ], 
            "name": "Nature Medicine", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "11", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "13"
          }
        ], 
        "name": "Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins", 
        "pagination": "1359-1362", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "ff399b7fc7550bf446d43266ffbbf327b95604435b92e0e0c498bfe675056b71"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "17934472"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9502015"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/nm1653"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1053583368"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/nm1653", 
          "https://app.dimensions.ai/details/publication/pub.1053583368"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T18:08", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8675_00000426.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/nm1653"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nm1653'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nm1653'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nm1653'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nm1653'


     

    This table displays all metadata directly associated to this object as RDF triples.

    355 TRIPLES      21 PREDICATES      51 URIs      28 LITERALS      16 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/nm1653 schema:about N0aad6139282e45a69593bd36894183a4
    2 N5e2b1ef86e904434969023eab91100d2
    3 N5ed4383e5a3740a59f8cd38d1454c7e3
    4 Nc0a669e0433640c6897c2cd8e8a3d840
    5 Nd4819591b046428487aab56781c8082e
    6 Nd5145de5da144a7ba0aa4dfd08990990
    7 Nd5a97ff348234cc6abd15d160589d0d2
    8 anzsrc-for:06
    9 anzsrc-for:0601
    10 schema:author N737b5b13e48647a6be448595b3bcab3c
    11 schema:citation sg:pub.10.1038/ni1078
    12 sg:pub.10.1385/1-59259-759-9:215
    13 https://app.dimensions.ai/details/publication/pub.1026133541
    14 https://doi.org/10.1016/j.neurobiolaging.2006.08.004
    15 https://doi.org/10.1016/j.neuron.2006.01.022
    16 https://doi.org/10.1016/s0074-7742(07)82011-3
    17 https://doi.org/10.1016/s0140-6736(06)69113-7
    18 https://doi.org/10.1016/s1474-4422(06)70355-6
    19 https://doi.org/10.1073/pnas.0308512100
    20 https://doi.org/10.1073/pnas.0610204104
    21 https://doi.org/10.1073/pnas.082099299
    22 https://doi.org/10.1073/pnas.091062498
    23 https://doi.org/10.1212/01.wnl.0000137040.64252.ed
    24 https://doi.org/10.1212/wnl.59.7.1034
    25 https://doi.org/10.2174/156720505774330573
    26 schema:datePublished 2007-11
    27 schema:datePublishedReg 2007-11-01
    28 schema:description A molecular test for Alzheimer's disease could lead to better treatment and therapies. We found 18 signaling proteins in blood plasma that can be used to classify blinded samples from Alzheimer's and control subjects with close to 90% accuracy and to identify patients who had mild cognitive impairment that progressed to Alzheimer's disease 2-6 years later. Biological analysis of the 18 proteins points to systemic dysregulation of hematopoiesis, immune responses, apoptosis and neuronal support in presymptomatic Alzheimer's disease.
    29 schema:genre research_article
    30 schema:inLanguage en
    31 schema:isAccessibleForFree false
    32 schema:isPartOf N6d9c003a03ca45d082d23ffdeb0adcc7
    33 Nb1c7a37cf38648adb1ab1065345b9895
    34 sg:journal.1113716
    35 schema:name Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins
    36 schema:pagination 1359-1362
    37 schema:productId N48c2f20a72a3431ea2da179c7992b0cc
    38 N8ec7e1c9f406486c8d772939d5e396db
    39 Nc45d8cb8ec6b4d78af820a07cfeacfde
    40 Nc5bb7a9d7d4c4de38fd9bdf08adf7db7
    41 Ne81d5e12a3c74d7387ddc18d422a1ddd
    42 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053583368
    43 https://doi.org/10.1038/nm1653
    44 schema:sdDatePublished 2019-04-10T18:08
    45 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    46 schema:sdPublisher N80ce40e678e645389ade458ff140887e
    47 schema:url http://www.nature.com/articles/nm1653
    48 sgo:license sg:explorer/license/
    49 sgo:sdDataset articles
    50 rdf:type schema:ScholarlyArticle
    51 N00281698ba8c41fcb5cb0b3a8c0cdd3f rdf:first sg:person.07606016437.66
    52 rdf:rest N07214fe8ef484bd0969c0b942a2816db
    53 N07214fe8ef484bd0969c0b942a2816db rdf:first sg:person.01021076041.88
    54 rdf:rest Nee2de5043d384c419fcc36e7144aedb2
    55 N0aad6139282e45a69593bd36894183a4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    56 schema:name Intercellular Signaling Peptides and Proteins
    57 rdf:type schema:DefinedTerm
    58 N12c49fdad1d140a894df14392bd9d341 rdf:first sg:person.0602425313.66
    59 rdf:rest Nc8d7965aa38c4a3f8cdbeb1c2fe5d66a
    60 N1a5bc97ad05a47088a93f9cb3acea5bc schema:name Institute of Clinical Neuroscience, Department of Experimental Neuroscience, Sahlgrenska University Hospital, University of Göteborg, Blå stråket 15, 431 80 Mölndal, Sweden.
    61 rdf:type schema:Organization
    62 N31b1d75a26814c92915ff5aa8346cf48 schema:affiliation N5e3459706435488c81eeec21a99601ac
    63 schema:familyName Herbert
    64 schema:givenName Charles
    65 rdf:type schema:Person
    66 N32090ae54c3e4bfbaa72bd4207db4c81 schema:name Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA.
    67 rdf:type schema:Organization
    68 N3fcb5ef2009f4cfda555079fcfcc5a0a schema:name Clinical Memory Research Unit, Department of Clinical Sciences Malmö, Lund University, Universitetssjukhuset MAS, Ingång 56 plan 7, SE-205 02 Malmö, Sweden.
    69 rdf:type schema:Organization
    70 N48c2f20a72a3431ea2da179c7992b0cc schema:name dimensions_id
    71 schema:value pub.1053583368
    72 rdf:type schema:PropertyValue
    73 N5860a7f45d73498f8fc6b31054c03b9b rdf:first sg:person.01265567037.05
    74 rdf:rest N866df2a8879d4b5a9ed98bbcfbda1e9c
    75 N5c1c0c7b2a6842aea7d2839bd1a4e573 rdf:first sg:person.01340560123.00
    76 rdf:rest N9d3e555b967f4ff2b87905ae56be1b80
    77 N5e2b1ef86e904434969023eab91100d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    78 schema:name Biomarkers
    79 rdf:type schema:DefinedTerm
    80 N5e3459706435488c81eeec21a99601ac schema:name Satoris, Inc., 2686 Middlefield Road, Suite E, Redwood City, California 94063, USA.
    81 rdf:type schema:Organization
    82 N5ed4383e5a3740a59f8cd38d1454c7e3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    83 schema:name Alzheimer Disease
    84 rdf:type schema:DefinedTerm
    85 N6b7d93e3c25945f888ba8b9cc1cb7ed1 rdf:first sg:person.0652607533.78
    86 rdf:rest N00281698ba8c41fcb5cb0b3a8c0cdd3f
    87 N6d9c003a03ca45d082d23ffdeb0adcc7 schema:issueNumber 11
    88 rdf:type schema:PublicationIssue
    89 N72a062015d904db981f40ef17151b2c7 schema:name Satoris, Inc., 2686 Middlefield Road, Suite E, Redwood City, California 94063, USA.
    90 rdf:type schema:Organization
    91 N72db4c90fe94490f904201ed3a822a19 rdf:first sg:person.01017510072.56
    92 rdf:rest rdf:nil
    93 N737b5b13e48647a6be448595b3bcab3c rdf:first sg:person.01154200405.63
    94 rdf:rest N5860a7f45d73498f8fc6b31054c03b9b
    95 N7c06faca10874cb5b6039468141fe3c3 rdf:first sg:person.01023325552.26
    96 rdf:rest N12c49fdad1d140a894df14392bd9d341
    97 N7cc80bc0ea5940178fbd513925ad7418 schema:name Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA.
    98 rdf:type schema:Organization
    99 N80ce40e678e645389ade458ff140887e schema:name Springer Nature - SN SciGraph project
    100 rdf:type schema:Organization
    101 N8657faee6f174258bc7cb4a76c063068 rdf:first sg:person.01075403326.32
    102 rdf:rest Need4d9a7ece943debdb42daaf146bf56
    103 N866df2a8879d4b5a9ed98bbcfbda1e9c rdf:first N31b1d75a26814c92915ff5aa8346cf48
    104 rdf:rest Nea8abc12694047cab2a643400a74c240
    105 N88229b407c2347eeaa34740fdc13a2ab rdf:first sg:person.01066747640.64
    106 rdf:rest N7c06faca10874cb5b6039468141fe3c3
    107 N8ec7e1c9f406486c8d772939d5e396db schema:name readcube_id
    108 schema:value ff399b7fc7550bf446d43266ffbbf327b95604435b92e0e0c498bfe675056b71
    109 rdf:type schema:PropertyValue
    110 N914ce78b90c24c99b44b109dbd1e7094 schema:name Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA.
    111 rdf:type schema:Organization
    112 N92ac1ef6dede4fb0b55015290374642d schema:name Department of Neurology, Memory and Aging Center, 350 Parnassus Avenue, Suite 706, San Francisco, California 94117, USA.
    113 rdf:type schema:Organization
    114 N9d3e555b967f4ff2b87905ae56be1b80 rdf:first sg:person.010253467037.73
    115 rdf:rest N72db4c90fe94490f904201ed3a822a19
    116 Na5eaaa56d39741d9845fc9eb166070ed rdf:first sg:person.01046002560.39
    117 rdf:rest Ndcc26484ee464b119b5177dbd4b71ae3
    118 Nb1c7a37cf38648adb1ab1065345b9895 schema:volumeNumber 13
    119 rdf:type schema:PublicationVolume
    120 Nb6f0c8960565417eb53e6b720ecb3dcc rdf:first sg:person.0707625530.62
    121 rdf:rest N88229b407c2347eeaa34740fdc13a2ab
    122 Nc0a669e0433640c6897c2cd8e8a3d840 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    123 schema:name Predictive Value of Tests
    124 rdf:type schema:DefinedTerm
    125 Nc45d8cb8ec6b4d78af820a07cfeacfde schema:name doi
    126 schema:value 10.1038/nm1653
    127 rdf:type schema:PropertyValue
    128 Nc5bb7a9d7d4c4de38fd9bdf08adf7db7 schema:name pubmed_id
    129 schema:value 17934472
    130 rdf:type schema:PropertyValue
    131 Nc8d7965aa38c4a3f8cdbeb1c2fe5d66a rdf:first sg:person.01012120344.19
    132 rdf:rest N5c1c0c7b2a6842aea7d2839bd1a4e573
    133 Ncc791964f93f48efb4beaf978f6b0c46 rdf:first sg:person.0673065763.63
    134 rdf:rest Nf77a3b671d494c178f8f38c552d09d18
    135 Nd4819591b046428487aab56781c8082e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    136 schema:name Humans
    137 rdf:type schema:DefinedTerm
    138 Nd5145de5da144a7ba0aa4dfd08990990 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    139 schema:name Phenotype
    140 rdf:type schema:DefinedTerm
    141 Nd5a97ff348234cc6abd15d160589d0d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    142 schema:name Cognition Disorders
    143 rdf:type schema:DefinedTerm
    144 Ndcc26484ee464b119b5177dbd4b71ae3 rdf:first sg:person.016530504722.42
    145 rdf:rest N8657faee6f174258bc7cb4a76c063068
    146 Ndffed74c14ab42f9966795ef160cb244 rdf:first sg:person.0741441174.74
    147 rdf:rest Neb33ff4e839d4186ab946e81eb3a5a3f
    148 Ne81d5e12a3c74d7387ddc18d422a1ddd schema:name nlm_unique_id
    149 schema:value 9502015
    150 rdf:type schema:PropertyValue
    151 Nea8abc12694047cab2a643400a74c240 rdf:first sg:person.01307235400.95
    152 rdf:rest N6b7d93e3c25945f888ba8b9cc1cb7ed1
    153 Neb33ff4e839d4186ab946e81eb3a5a3f rdf:first sg:person.013136240367.86
    154 rdf:rest Na5eaaa56d39741d9845fc9eb166070ed
    155 Nee2de5043d384c419fcc36e7144aedb2 rdf:first sg:person.014114612457.85
    156 rdf:rest Ncc791964f93f48efb4beaf978f6b0c46
    157 Need4d9a7ece943debdb42daaf146bf56 rdf:first sg:person.01036436624.26
    158 rdf:rest Nb6f0c8960565417eb53e6b720ecb3dcc
    159 Nf77a3b671d494c178f8f38c552d09d18 rdf:first sg:person.01320644065.52
    160 rdf:rest Nfb2d9de17a6d472cad1210c606efd6f2
    161 Nfb2d9de17a6d472cad1210c606efd6f2 rdf:first sg:person.015720613277.48
    162 rdf:rest Ndffed74c14ab42f9966795ef160cb244
    163 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    164 schema:name Biological Sciences
    165 rdf:type schema:DefinedTerm
    166 anzsrc-for:0601 schema:inDefinedTermSet anzsrc-for:
    167 schema:name Biochemistry and Cell Biology
    168 rdf:type schema:DefinedTerm
    169 sg:grant.2438583 http://pending.schema.org/fundedItem sg:pub.10.1038/nm1653
    170 rdf:type schema:MonetaryGrant
    171 sg:grant.2440005 http://pending.schema.org/fundedItem sg:pub.10.1038/nm1653
    172 rdf:type schema:MonetaryGrant
    173 sg:grant.2447294 http://pending.schema.org/fundedItem sg:pub.10.1038/nm1653
    174 rdf:type schema:MonetaryGrant
    175 sg:journal.1113716 schema:issn 1078-8956
    176 1546-170X
    177 schema:name Nature Medicine
    178 rdf:type schema:Periodical
    179 sg:person.01012120344.19 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    180 schema:familyName Tinklenberg
    181 schema:givenName Jared
    182 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01012120344.19
    183 rdf:type schema:Person
    184 sg:person.01017510072.56 schema:affiliation https://www.grid.ac/institutes/grid.280747.e
    185 schema:familyName Wyss-Coray
    186 schema:givenName Tony
    187 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017510072.56
    188 rdf:type schema:Person
    189 sg:person.01021076041.88 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    190 schema:familyName Friedman
    191 schema:givenName Leah F
    192 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01021076041.88
    193 rdf:type schema:Person
    194 sg:person.01023325552.26 schema:affiliation https://www.grid.ac/institutes/grid.414208.b
    195 schema:familyName Sparks
    196 schema:givenName D Larry
    197 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01023325552.26
    198 rdf:type schema:Person
    199 sg:person.010253467037.73 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    200 schema:familyName Tibshirani
    201 schema:givenName Robert
    202 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010253467037.73
    203 rdf:type schema:Person
    204 sg:person.01036436624.26 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    205 schema:familyName Robinson
    206 schema:givenName William H
    207 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01036436624.26
    208 rdf:type schema:Person
    209 sg:person.01046002560.39 schema:affiliation N3fcb5ef2009f4cfda555079fcfcc5a0a
    210 schema:familyName Minthon
    211 schema:givenName Lennart
    212 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01046002560.39
    213 rdf:type schema:Person
    214 sg:person.01066747640.64 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    215 schema:familyName So
    216 schema:givenName Yuen T
    217 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01066747640.64
    218 rdf:type schema:Person
    219 sg:person.01075403326.32 schema:affiliation N92ac1ef6dede4fb0b55015290374642d
    220 schema:familyName Rabinovici
    221 schema:givenName Gil D
    222 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075403326.32
    223 rdf:type schema:Person
    224 sg:person.01154200405.63 schema:affiliation N72a062015d904db981f40ef17151b2c7
    225 schema:familyName Ray
    226 schema:givenName Sandip
    227 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01154200405.63
    228 rdf:type schema:Person
    229 sg:person.01265567037.05 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    230 schema:familyName Britschgi
    231 schema:givenName Markus
    232 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01265567037.05
    233 rdf:type schema:Person
    234 sg:person.01307235400.95 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    235 schema:familyName Takeda-Uchimura
    236 schema:givenName Yoshiko
    237 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01307235400.95
    238 rdf:type schema:Person
    239 sg:person.013136240367.86 schema:affiliation N914ce78b90c24c99b44b109dbd1e7094
    240 schema:familyName Miller
    241 schema:givenName Bruce L
    242 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013136240367.86
    243 rdf:type schema:Person
    244 sg:person.01320644065.52 schema:affiliation N32090ae54c3e4bfbaa72bd4207db4c81
    245 schema:familyName Karydas
    246 schema:givenName Anna
    247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320644065.52
    248 rdf:type schema:Person
    249 sg:person.01340560123.00 schema:affiliation https://www.grid.ac/institutes/grid.168010.e
    250 schema:familyName Yesavage
    251 schema:givenName Jerome A
    252 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01340560123.00
    253 rdf:type schema:Person
    254 sg:person.014114612457.85 schema:affiliation https://www.grid.ac/institutes/grid.266100.3
    255 schema:familyName Galasko
    256 schema:givenName Douglas R
    257 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014114612457.85
    258 rdf:type schema:Person
    259 sg:person.015720613277.48 schema:affiliation https://www.grid.ac/institutes/grid.5288.7
    260 schema:familyName Kaye
    261 schema:givenName Jeffrey A
    262 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015720613277.48
    263 rdf:type schema:Person
    264 sg:person.016530504722.42 schema:affiliation https://www.grid.ac/institutes/grid.5288.7
    265 schema:familyName Quinn
    266 schema:givenName Joseph F
    267 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016530504722.42
    268 rdf:type schema:Person
    269 sg:person.0602425313.66 schema:affiliation https://www.grid.ac/institutes/grid.5606.5
    270 schema:familyName Tabaton
    271 schema:givenName Massimo
    272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602425313.66
    273 rdf:type schema:Person
    274 sg:person.0652607533.78 schema:affiliation N7cc80bc0ea5940178fbd513925ad7418
    275 schema:familyName Boxer
    276 schema:givenName Adam
    277 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0652607533.78
    278 rdf:type schema:Person
    279 sg:person.0673065763.63 schema:affiliation https://www.grid.ac/institutes/grid.4495.c
    280 schema:familyName Jutel
    281 schema:givenName Marek
    282 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0673065763.63
    283 rdf:type schema:Person
    284 sg:person.0707625530.62 schema:affiliation https://www.grid.ac/institutes/grid.414208.b
    285 schema:familyName Sabbagh
    286 schema:givenName Marwan N
    287 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0707625530.62
    288 rdf:type schema:Person
    289 sg:person.0741441174.74 schema:affiliation https://www.grid.ac/institutes/grid.4495.c
    290 schema:familyName Leszek
    291 schema:givenName Jerzy
    292 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0741441174.74
    293 rdf:type schema:Person
    294 sg:person.07606016437.66 schema:affiliation N1a5bc97ad05a47088a93f9cb3acea5bc
    295 schema:familyName Blennow
    296 schema:givenName Kaj
    297 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07606016437.66
    298 rdf:type schema:Person
    299 sg:pub.10.1038/ni1078 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048922409
    300 https://doi.org/10.1038/ni1078
    301 rdf:type schema:CreativeWork
    302 sg:pub.10.1385/1-59259-759-9:215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046551425
    303 https://doi.org/10.1385/1-59259-759-9:215
    304 rdf:type schema:CreativeWork
    305 https://app.dimensions.ai/details/publication/pub.1026133541 schema:CreativeWork
    306 https://doi.org/10.1016/j.neurobiolaging.2006.08.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038551375
    307 rdf:type schema:CreativeWork
    308 https://doi.org/10.1016/j.neuron.2006.01.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006192059
    309 rdf:type schema:CreativeWork
    310 https://doi.org/10.1016/s0074-7742(07)82011-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048282183
    311 rdf:type schema:CreativeWork
    312 https://doi.org/10.1016/s0140-6736(06)69113-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038428900
    313 rdf:type schema:CreativeWork
    314 https://doi.org/10.1016/s1474-4422(06)70355-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039309033
    315 rdf:type schema:CreativeWork
    316 https://doi.org/10.1073/pnas.0308512100 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007985703
    317 rdf:type schema:CreativeWork
    318 https://doi.org/10.1073/pnas.0610204104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042762077
    319 rdf:type schema:CreativeWork
    320 https://doi.org/10.1073/pnas.082099299 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037994416
    321 rdf:type schema:CreativeWork
    322 https://doi.org/10.1073/pnas.091062498 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001631710
    323 rdf:type schema:CreativeWork
    324 https://doi.org/10.1212/01.wnl.0000137040.64252.ed schema:sameAs https://app.dimensions.ai/details/publication/pub.1064346292
    325 rdf:type schema:CreativeWork
    326 https://doi.org/10.1212/wnl.59.7.1034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064381192
    327 rdf:type schema:CreativeWork
    328 https://doi.org/10.2174/156720505774330573 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069188624
    329 rdf:type schema:CreativeWork
    330 https://www.grid.ac/institutes/grid.168010.e schema:alternateName Stanford University
    331 schema:name Department of Health Research and Policy, Stanford University School of Medicine, Stanford, 300 Pasteur Drive, California 94305-5405, USA.
    332 Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA.
    333 Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5550, USA.
    334 Division of Immunology and Rheumatology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5166, USA.
    335 rdf:type schema:Organization
    336 https://www.grid.ac/institutes/grid.266100.3 schema:alternateName University of California, San Diego
    337 schema:name Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive #9127, La Jolla, California 92093-9127, USA.
    338 rdf:type schema:Organization
    339 https://www.grid.ac/institutes/grid.280747.e schema:alternateName VA Palo Alto Health Care System
    340 schema:name Department of Neurology and Neurological Sciences, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305-5235, USA.
    341 Geriatric Research, Education and Clinical Center, Veterans Affairs Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, California 94304, USA.
    342 rdf:type schema:Organization
    343 https://www.grid.ac/institutes/grid.414208.b schema:alternateName Banner Sun Health Research Institute
    344 schema:name Sun Health Research Institute, 10515 West Santa Fe Drive, Sun City, Arizona 85351, USA.
    345 rdf:type schema:Organization
    346 https://www.grid.ac/institutes/grid.4495.c schema:alternateName Wrocław Medical University
    347 schema:name Department of Internal Medicine and Allergology, Wroclaw Medical University, Traugutta 57, 50-417 Wroclaw, Poland.
    348 Department of Psychiatry, Wroclaw Medical University, Pasteura 10, 51-622 Wroclaw, Poland.
    349 rdf:type schema:Organization
    350 https://www.grid.ac/institutes/grid.5288.7 schema:alternateName Oregon Health & Science University
    351 schema:name Layton Aging & Alzheimer's Disease Center, Oregon Health Sciences University, 3181 Southwest Sam Jackson Park Road, CR131, Portland, Oregon 97201-3098, USA.
    352 rdf:type schema:Organization
    353 https://www.grid.ac/institutes/grid.5606.5 schema:alternateName University of Genoa
    354 schema:name Department of Neurosciences, Ophthalmology, and Genetics, University of Genoa, Via A. De Toni 5, 16132 Genoa, Italy.
    355 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...