Cancer immunotherapy: moving beyond current vaccines View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2004-09

AUTHORS

Steven A Rosenberg, James C Yang, Nicholas P Restifo

ABSTRACT

Great progress has been made in the field of tumor immunology in the past decade, but optimism about the clinical application of currently available cancer vaccine approaches is based more on surrogate endpoints than on clinical tumor regression. In our cancer vaccine trials of 440 patients, the objective response rate was low (2.6%), and comparable to the results obtained by others. We consider here results in cancer vaccine trials and highlight alternate strategies that mediate cancer regression in preclinical and clinical models. More... »

PAGES

909-915

Journal

TITLE

Nature Medicine

ISSUE

9

VOLUME

10

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nm1100

    DOI

    http://dx.doi.org/10.1038/nm1100

    DIMENSIONS

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    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/15340416


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