2004-08
AUTHORSBert Vogelstein, Kenneth W Kinzler
ABSTRACTThe revolution in cancer research can be summed up in a single sentence: cancer is, in essence, a genetic disease. In the last decade, many important genes responsible for the genesis of various cancers have been discovered, their mutations precisely identified, and the pathways through which they act characterized. The purposes of this review are to highlight examples of progress in these areas, indicate where knowledge is scarce and point out fertile grounds for future investigation. More... »
PAGES789
http://scigraph.springernature.com/pub.10.1038/nm1087
DOIhttp://dx.doi.org/10.1038/nm1087
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1026059473
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/15286780
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1112",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Oncology and Carcinogenesis",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adenomatous Polyposis Coli Protein",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Apoptosis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA Repair",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA-Binding Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genes, Tumor Suppressor",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hypoxia-Inducible Factor 1",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Hypoxia-Inducible Factor 1, alpha Subunit",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Mutation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Neoplasms",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Nuclear Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oncogenes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Phosphatidylinositol 3-Kinases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Receptor Protein-Tyrosine Kinases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Retinoblastoma Protein",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Signal Transduction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Smad Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Trans-Activators",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Transcription Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tumor Suppressor Protein p53",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Zinc Finger Protein GLI1",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Johns Hopkins University",
"id": "https://www.grid.ac/institutes/grid.21107.35",
"name": [
"Howard Hughes Medical Institute and The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University Medical Institutions, Baltimore, Maryland 21231, USA. vogelbe@welch.jhu.edu"
],
"type": "Organization"
},
"familyName": "Vogelstein",
"givenName": "Bert",
"id": "sg:person.011173760757.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011173760757.54"
],
"type": "Person"
},
{
"familyName": "Kinzler",
"givenName": "Kenneth W",
"id": "sg:person.0620642630.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620642630.54"
],
"type": "Person"
}
],
"citation": [
{
"id": "https://doi.org/10.1016/s0921-8777(98)00056-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000165638"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1535-6108(03)00195-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000251184"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bst0310437",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001136382"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1042/bst0310437",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001136382"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/path.1473",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001168351"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(02)00621-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001655891"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt965",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002043855",
"https://doi.org/10.1038/nbt965"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt965",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002043855",
"https://doi.org/10.1038/nbt965"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.med.55.091902.105237",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003367401"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1081/cnv-120025096",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003817087"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/1043-4682(95)90014-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003862203"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/1078-0432.ccr-0835-03",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004436962"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0022-5193(03)00120-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004876503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0022-5193(03)00120-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1004876503"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0959-437x(97)80117-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005501565"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/ajmg.10320",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1005846684"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.genet.32.1.495",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006399883"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmra012242",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006436118"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrd1381",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006489607",
"https://doi.org/10.1038/nrd1381"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrd1381",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006489607",
"https://doi.org/10.1038/nrd1381"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(00)81688-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006800132"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/0016-5085(95)90092-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006844421"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(04)00046-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009019174"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1279",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009116910",
"https://doi.org/10.1038/nrc1279"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1279",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009116910",
"https://doi.org/10.1038/nrc1279"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0168-1702(02)00190-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010549658"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35044000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011057053",
"https://doi.org/10.1038/35044000"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35044000",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011057053",
"https://doi.org/10.1038/35044000"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0334858100",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012164715"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature01626",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012394158",
"https://doi.org/10.1038/nature01626"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature01626",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012394158",
"https://doi.org/10.1038/nature01626"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1098/rstb.2003.1370",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012409630"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(04)00038-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012435077"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm0103-123",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012543788",
"https://doi.org/10.1038/nm0103-123"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm0103-123",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012543788",
"https://doi.org/10.1038/nm0103-123"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1165",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014080321",
"https://doi.org/10.1038/nrc1165"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1165",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014080321",
"https://doi.org/10.1038/nrc1165"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng721",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014242812",
"https://doi.org/10.1038/ng721"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng721",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014242812",
"https://doi.org/10.1038/ng721"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0959-437x(00)00156-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014641562"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(00)81333-1",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1014745301"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02313",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016242812",
"https://doi.org/10.1038/nature02313"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02313",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016242812",
"https://doi.org/10.1038/nature02313"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-419x(02)00037-9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1016551188"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1043-2760(01)00528-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017278946"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/4462",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017284394",
"https://doi.org/10.1038/4462"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/4462",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017284394",
"https://doi.org/10.1038/4462"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc905",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017804909",
"https://doi.org/10.1038/nrc905"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc905",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017804909",
"https://doi.org/10.1038/nrc905"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02370",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018499830",
"https://doi.org/10.1038/nature02370"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc865",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019149476",
"https://doi.org/10.1038/nrc865"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc865",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019149476",
"https://doi.org/10.1038/nrc865"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(04)00215-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019563286"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/cbic.200300614",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1019669577"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1158/0008-5472.can-03-3249",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021034985"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1299",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022731034",
"https://doi.org/10.1038/nrc1299"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1299",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022731034",
"https://doi.org/10.1038/nrc1299"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1098020",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023265646"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature00766",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023536940",
"https://doi.org/10.1038/nature00766"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature00766",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023536940",
"https://doi.org/10.1038/nature00766"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35042675",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023763406",
"https://doi.org/10.1038/35042675"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35042675",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023763406",
"https://doi.org/10.1038/35042675"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1535-6108(02)00024-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1025305263"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature01408",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026406086",
"https://doi.org/10.1038/nature01408"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature01408",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1026406086",
"https://doi.org/10.1038/nature01408"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029050274",
"https://doi.org/10.1038/nrc1013"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1013",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029050274",
"https://doi.org/10.1038/nrc1013"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35106065",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029289076",
"https://doi.org/10.1038/35106065"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/35106065",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029289076",
"https://doi.org/10.1038/35106065"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00428-003-0945-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1029402834",
"https://doi.org/10.1007/s00428-003-0945-5"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.arcmed.2003.08.007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030244548"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1207518",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032262451",
"https://doi.org/10.1038/sj.onc.1207518"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1207518",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032262451",
"https://doi.org/10.1038/sj.onc.1207518"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1066355",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032271966"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1099314",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033538744"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/25292",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033871070",
"https://doi.org/10.1038/25292"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/25292",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033871070",
"https://doi.org/10.1038/25292"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.cdd.4401183",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033941123",
"https://doi.org/10.1038/sj.cdd.4401183"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.cdd.4401183",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033941123",
"https://doi.org/10.1038/sj.cdd.4401183"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034382167",
"https://doi.org/10.1038/nrc1187"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034382167",
"https://doi.org/10.1038/nrc1187"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1187",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034382167",
"https://doi.org/10.1038/nrc1187"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.261714699",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035417307"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0092-8674(03)00432-x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1035867530"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1146/annurev.bi.56.070187.004023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036230576"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0400027101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1036923543"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1093/hmg/ddg261",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038614684"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1205062",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038732911",
"https://doi.org/10.1038/sj.onc.1205062"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1205062",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038732911",
"https://doi.org/10.1038/sj.onc.1205062"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1204958",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040392290",
"https://doi.org/10.1038/sj.onc.1204958"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1204958",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1040392290",
"https://doi.org/10.1038/sj.onc.1204958"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1073/pnas.0401064101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1041790673"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1096-9896(199901)187:1<127::aid-path251>3.0.co;2-t",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042407643"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1096-9896(199901)187:1<127::aid-path251>3.0.co;2-t",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042407643"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1056/nejmoa040938",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042907590"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1101/gad.1158703",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043077214"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc950",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043159681",
"https://doi.org/10.1038/nrc950"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc950",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043159681",
"https://doi.org/10.1038/nrc950"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1101/gad.1126903",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043461593"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1535-6108(02)00043-0",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043492711"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.296.5573.1655",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043624396"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1186/bcr634",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043640926",
"https://doi.org/10.1186/bcr634"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1096-9896(199901)187:1<112::aid-path250>3.0.co;2-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043798122"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/(sici)1096-9896(199901)187:1<112::aid-path250>3.0.co;2-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043798122"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1360",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043890593",
"https://doi.org/10.1038/nrc1360"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1360",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043890593",
"https://doi.org/10.1038/nrc1360"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1142",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044133013",
"https://doi.org/10.1038/nrc1142"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1142",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044133013",
"https://doi.org/10.1038/nrc1142"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s005350200015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044358823",
"https://doi.org/10.1007/s005350200015"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc969",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044435378",
"https://doi.org/10.1038/nrc969"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc969",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044435378",
"https://doi.org/10.1038/nrc969"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1046/j.1365-2796.2003.01098.x",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044576780"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1170",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044830086",
"https://doi.org/10.1038/nrc1170"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1170",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044830086",
"https://doi.org/10.1038/nrc1170"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/978-1-4757-3147-7_4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045758901",
"https://doi.org/10.1007/978-1-4757-3147-7_4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1207130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045968723",
"https://doi.org/10.1038/sj.onc.1207130"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.onc.1207130",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045968723",
"https://doi.org/10.1038/sj.onc.1207130"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0065-230x(01)83007-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047767510"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ccr.2004.05.015",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048372678"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1006/scbi.2001.0416",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048653187"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1054/drup.2001.0193",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048695296"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1081/cnv-120027585",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049667154"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc755",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049934401",
"https://doi.org/10.1038/nrc755"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc755",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049934401",
"https://doi.org/10.1038/nrc755"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-3835(03)00451-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050170415"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-3835(03)00451-8",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050170415"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1002/path.1521",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050184498"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.bbcan.2004.01.001",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050297866"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrg1085",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050771152",
"https://doi.org/10.1038/nrg1085"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrg1085",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050771152",
"https://doi.org/10.1038/nrg1085"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1383-5742(00)00006-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051265552"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-419x(03)00005-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051853060"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0304-419x(03)00005-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1051853060"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6601590",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052072322",
"https://doi.org/10.1038/sj.bjc.6601590"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.bjc.6601590",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052072322",
"https://doi.org/10.1038/sj.bjc.6601590"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s1044-579x(02)00012-3",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052338237"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/j.ijrobp.2003.09.099",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052696640"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature02371",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053454880",
"https://doi.org/10.1038/nature02371"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrg816",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053491434",
"https://doi.org/10.1038/nrg816"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrg816",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053491434",
"https://doi.org/10.1038/nrg816"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/sonc.2002.34874",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057078558"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1016/s0093-7754(02)90009-6",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057078558"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/sonc.2002.37263",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057078577"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1053/sonc.2002.37263",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1057078577"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.1094732",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062449385"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1126/science.297.5581.565",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1062577832"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2741/a726",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070917509"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.2741/klein",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1070919340"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/cc.1.2.108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072295781"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.4161/cc.2.3.382",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1072296761"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074261115",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074588346",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074677015",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1074689096",
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.14670/hh-16.669",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074808123"
],
"type": "CreativeWork"
},
{
"id": "https://doi.org/10.1200/jco.2001.19.11.2948",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1074829008"
],
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1075097684",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1079010052",
"type": "CreativeWork"
},
{
"id": "https://app.dimensions.ai/details/publication/pub.1082566696",
"type": "CreativeWork"
}
],
"datePublished": "2004-08",
"datePublishedReg": "2004-08-01",
"description": "The revolution in cancer research can be summed up in a single sentence: cancer is, in essence, a genetic disease. In the last decade, many important genes responsible for the genesis of various cancers have been discovered, their mutations precisely identified, and the pathways through which they act characterized. The purposes of this review are to highlight examples of progress in these areas, indicate where knowledge is scarce and point out fertile grounds for future investigation.",
"genre": "research_article",
"id": "sg:pub.10.1038/nm1087",
"inLanguage": [
"en"
],
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.2440141",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2469185",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2634325",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2634365",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.2471197",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1113716",
"issn": [
"1078-8956",
"1546-170X"
],
"name": "Nature Medicine",
"type": "Periodical"
},
{
"issueNumber": "8",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "10"
}
],
"name": "Cancer genes and the pathways they control",
"pagination": "789",
"productId": [
{
"name": "readcube_id",
"type": "PropertyValue",
"value": [
"7c257699962f49864baf41dc429dbd26aed0de9dfa03bd5ab32c06f12b1bb5a6"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"15286780"
]
},
{
"name": "nlm_unique_id",
"type": "PropertyValue",
"value": [
"9502015"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/nm1087"
]
},
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1026059473"
]
}
],
"sameAs": [
"https://doi.org/10.1038/nm1087",
"https://app.dimensions.ai/details/publication/pub.1026059473"
],
"sdDataset": "articles",
"sdDatePublished": "2019-04-11T12:22",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000362_0000000362/records_87088_00000000.jsonl",
"type": "ScholarlyArticle",
"url": "https://www.nature.com/articles/nm1087"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nm1087'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nm1087'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nm1087'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nm1087'
This table displays all metadata directly associated to this object as RDF triples.
553 TRIPLES
21 PREDICATES
167 URIs
42 LITERALS
30 BLANK NODES