Presenilins, amyloid-β and Alzheimer's disease View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1997-01

AUTHORS

Bruce T. Lamb

ABSTRACT

N/A

PAGES

28-29

References to SciGraph publications

  • 1996-10. The E280A presenilin 1 Alzheimer mutation produces increased Aβ42 deposition and severe cerebellar pathology in NATURE MEDICINE
  • 1996-08. Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease in NATURE MEDICINE
  • 1996-02. Alzheimer–associated presenilins 1 and 2 : Neuronal expression in brain and localization to intracellular membranes in mammalian cells in NATURE MEDICINE
  • 1995-08. Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene in NATURE
  • 1996-11. The Alzheimer’s Disease-Associated Presenilins Are Differentially Phosphorylated Proteins Located Predominantly within the Endoplasmic Reticulum in MOLECULAR MEDICINE
  • 1995-02. Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein in NATURE
  • 1995-10. The structure of the presenilin 1 (S182) gene and identification of six novel mutations in early onset AD families in NATURE GENETICS
  • 1995-06. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease in NATURE
  • 1997-01. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice in NATURE MEDICINE
  • 1996-10. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia in NATURE
  • 1996-10. Increased amyloid-β42(43) in brains of mice expressing mutant presenilin 1 in NATURE
  • Journal

    TITLE

    Nature Medicine

    ISSUE

    1

    VOLUME

    3

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/nm0197-28

    DOI

    http://dx.doi.org/10.1038/nm0197-28

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010870835

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/8986735


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