Catapulting clopidogrel pharmacogenomics forward View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2011-01

AUTHORS

Eric J Topol, Nicholas J Schork

ABSTRACT

The antiplatelet drug clopidogrel helps prevent stent-associated thrombosis, but the antiplatelet effects are quite variable and the clinical consequences can be serious. New findings show that the variability in clopidogrel efficacy is affected by the enzyme paraoxonase-1 (PON1), which is required for clopidogrel bioactivation (pages 110–116).

PAGES

40

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nm0111-40

DOI

http://dx.doi.org/10.1038/nm0111-40

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1005417168

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21217678


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