Ontology type: schema:ScholarlyArticle
2016-06-13
AUTHORSRuth Eichner, Michael Heider, Vanesa Fernández-Sáiz, Frauke van Bebber, Anne-Kathrin Garz, Simone Lemeer, Martina Rudelius, Bianca-Sabrina Targosz, Laura Jacobs, Anna-Maria Knorn, Jolanta Slawska, Uwe Platzbecker, Ulrich Germing, Christian Langer, Stefan Knop, Herrmann Einsele, Christian Peschel, Christian Haass, Ulrich Keller, Bettina Schmid, Katharina S Götze, Bernhard Kuster, Florian Bassermann
ABSTRACTThalidomide and its derivatives lenalidomide and pomalidomide, which are used to treat multiple myeloma and del(5q) myelodysplastic syndrome, have antitumor and teratogenic effects through a mechanism involving destabilization of the CD147 and MCT1 proteins.
PAGES735-743
http://scigraph.springernature.com/pub.10.1038/nm.4128
DOIhttp://dx.doi.org/10.1038/nm.4128
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1016584456
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/27294876
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Medical and Health Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1115",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Pharmacology and Pharmaceutical Sciences",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Adaptor Proteins, Signal Transducing",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Basigin",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Cycle Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunologic Factors",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Immunosuppressive Agents",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Lenalidomide",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Multiple Myeloma",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Myelodysplastic Syndromes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oncogene Proteins",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Peptide Hydrolases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "RNA, Messenger",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Reverse Transcriptase Polymerase Chain Reaction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Signal Transduction",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Teratogenesis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Thalidomide",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Ubiquitin-Protein Ligases",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Eichner",
"givenName": "Ruth",
"id": "sg:person.01075335574.69",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01075335574.69"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Heider",
"givenName": "Michael",
"id": "sg:person.012105145111.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012105145111.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "Fern\u00e1ndez-S\u00e1iz",
"givenName": "Vanesa",
"id": "sg:person.0703770144.71",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0703770144.71"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Center for Neurodegenerative Diseases (DZNE), Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.424247.3",
"name": [
"German Center for Neurodegenerative Diseases (DZNE), Munich, Germany"
],
"type": "Organization"
},
"familyName": "van Bebber",
"givenName": "Frauke",
"id": "sg:person.01210270054.10",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210270054.10"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "Garz",
"givenName": "Anne-Kathrin",
"id": "sg:person.010724363561.86",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010724363561.86"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Proteomics and Bioanalytics, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany",
"id": "http://www.grid.ac/institutes/grid.6936.a",
"name": [
"Department of Proteomics and Bioanalytics, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany"
],
"type": "Organization"
},
"familyName": "Lemeer",
"givenName": "Simone",
"id": "sg:person.01101610443.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01101610443.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Comprehensive Cancer Center Mainfranken, Universit\u00e4t W\u00fcrzburg, W\u00fcrzburg, Germany",
"id": "http://www.grid.ac/institutes/grid.512555.3",
"name": [
"Institute of Pathology, Universit\u00e4t W\u00fcrzburg, W\u00fcrzburg, Germany",
"Comprehensive Cancer Center Mainfranken, Universit\u00e4t W\u00fcrzburg, W\u00fcrzburg, Germany"
],
"type": "Organization"
},
"familyName": "Rudelius",
"givenName": "Martina",
"id": "sg:person.0642071404.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642071404.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Targosz",
"givenName": "Bianca-Sabrina",
"id": "sg:person.01157777441.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01157777441.20"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Jacobs",
"givenName": "Laura",
"id": "sg:person.07762736711.80",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07762736711.80"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Knorn",
"givenName": "Anna-Maria",
"id": "sg:person.01330742753.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01330742753.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.15474.33",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Slawska",
"givenName": "Jolanta",
"id": "sg:person.01111036510.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111036510.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medizinische Klinik und Poliklinik I, Universit\u00e4tsklinikum Carl\u2013Gustav\u2013Carus, Technische Universit\u00e4t, Dresden, Germany",
"id": "http://www.grid.ac/institutes/grid.412282.f",
"name": [
"Medizinische Klinik und Poliklinik I, Universit\u00e4tsklinikum Carl\u2013Gustav\u2013Carus, Technische Universit\u00e4t, Dresden, Germany"
],
"type": "Organization"
},
"familyName": "Platzbecker",
"givenName": "Uwe",
"id": "sg:person.0670313557.25",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0670313557.25"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Hematology, Oncology and Clinical Immunology, Heinrich\u2013Heine\u2013University, D\u00fcsseldorf, Germany",
"id": "http://www.grid.ac/institutes/grid.411327.2",
"name": [
"Department of Hematology, Oncology and Clinical Immunology, Heinrich\u2013Heine\u2013University, D\u00fcsseldorf, Germany"
],
"type": "Organization"
},
"familyName": "Germing",
"givenName": "Ulrich",
"id": "sg:person.01362464041.20",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01362464041.20"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Internal Medicine III, University of Ulm, Ulm, Germany",
"id": "http://www.grid.ac/institutes/grid.6582.9",
"name": [
"Department of Internal Medicine III, University of Ulm, Ulm, Germany"
],
"type": "Organization"
},
"familyName": "Langer",
"givenName": "Christian",
"id": "sg:person.01336076624.54",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01336076624.54"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Division of Hematology and Medical Oncology, Department of Internal Medicine II, W\u00fcrzburg University Medical Center, W\u00fcrzburg, Germany",
"id": "http://www.grid.ac/institutes/grid.8379.5",
"name": [
"Division of Hematology and Medical Oncology, Department of Internal Medicine II, W\u00fcrzburg University Medical Center, W\u00fcrzburg, Germany"
],
"type": "Organization"
},
"familyName": "Knop",
"givenName": "Stefan",
"id": "sg:person.01335356245.92",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01335356245.92"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Division of Hematology and Medical Oncology, Department of Internal Medicine II, W\u00fcrzburg University Medical Center, W\u00fcrzburg, Germany",
"id": "http://www.grid.ac/institutes/grid.8379.5",
"name": [
"Division of Hematology and Medical Oncology, Department of Internal Medicine II, W\u00fcrzburg University Medical Center, W\u00fcrzburg, Germany"
],
"type": "Organization"
},
"familyName": "Einsele",
"givenName": "Herrmann",
"id": "sg:person.01371060111.89",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01371060111.89"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "Peschel",
"givenName": "Christian",
"id": "sg:person.01053640121.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01053640121.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Biomedical Center, Ludwig\u2013Maximilians University Munich, Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.5252.0",
"name": [
"German Center for Neurodegenerative Diseases (DZNE), Munich, Germany",
"Munich Cluster for Systems Neurology (SyNergy), Munich, Germany",
"Biomedical Center, Ludwig\u2013Maximilians University Munich, Munich, Germany"
],
"type": "Organization"
},
"familyName": "Haass",
"givenName": "Christian",
"id": "sg:person.0677231073.35",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0677231073.35"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "Keller",
"givenName": "Ulrich",
"id": "sg:person.01351515546.18",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01351515546.18"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Munich Cluster for Systems Neurology (SyNergy), Munich, Germany",
"id": "http://www.grid.ac/institutes/grid.452617.3",
"name": [
"German Center for Neurodegenerative Diseases (DZNE), Munich, Germany",
"Munich Cluster for Systems Neurology (SyNergy), Munich, Germany"
],
"type": "Organization"
},
"familyName": "Schmid",
"givenName": "Bettina",
"id": "sg:person.0753751754.06",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753751754.06"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "G\u00f6tze",
"givenName": "Katharina S",
"id": "sg:person.01320201641.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01320201641.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Center for Integrated Protein Science Munich (CIPSM), Freising, Germany",
"id": "http://www.grid.ac/institutes/grid.452329.b",
"name": [
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany",
"Department of Proteomics and Bioanalytics, Technische Universit\u00e4t M\u00fcnchen, Freising, Germany",
"Center for Integrated Protein Science Munich (CIPSM), Freising, Germany"
],
"type": "Organization"
},
"familyName": "Kuster",
"givenName": "Bernhard",
"id": "sg:person.01365627301.74",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01365627301.74"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "German Cancer Research Center (DKFZ), Heidelberg, Germany",
"id": "http://www.grid.ac/institutes/grid.7497.d",
"name": [
"Department of Medicine III, Klinikum rechts der Isar, Technische Universit\u00e4t M\u00fcnchen, Munich, Germany",
"German Cancer Consortium (DKTK), Heidelberg, Germany",
"German Cancer Research Center (DKFZ), Heidelberg, Germany"
],
"type": "Organization"
},
"familyName": "Bassermann",
"givenName": "Florian",
"id": "sg:person.0614361251.77",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0614361251.77"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/nm.3740",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1032978680",
"https://doi.org/10.1038/nm.3740"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb2651",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039979468",
"https://doi.org/10.1038/ncb2651"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00277-013-1863-5",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1022553403",
"https://doi.org/10.1007/s00277-013-1863-5"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature13527",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1028080932",
"https://doi.org/10.1038/nature13527"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc3579",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1049443705",
"https://doi.org/10.1038/nrc3579"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nsmb.2874",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1042667121",
"https://doi.org/10.1038/nsmb.2874"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrc1323",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044837763",
"https://doi.org/10.1038/nrc1323"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature14610",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038212794",
"https://doi.org/10.1038/nature14610"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature16979",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1027760858",
"https://doi.org/10.1038/nature16979"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/leu.2012.91",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1006365398",
"https://doi.org/10.1038/leu.2012.91"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm.3867",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1020112427",
"https://doi.org/10.1038/nm.3867"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05175",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1038923345",
"https://doi.org/10.1038/nature05175"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/onc.2012.599",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1034046475",
"https://doi.org/10.1038/onc.2012.599"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng.2471",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1053270214",
"https://doi.org/10.1038/ng.2471"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/sj.leu.2402894",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001004907",
"https://doi.org/10.1038/sj.leu.2402894"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/leu.2012.119",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1008299299",
"https://doi.org/10.1038/leu.2012.119"
],
"type": "CreativeWork"
}
],
"datePublished": "2016-06-13",
"datePublishedReg": "2016-06-13",
"description": "Thalidomide and its derivatives lenalidomide and pomalidomide, which are used to treat multiple myeloma and del(5q) myelodysplastic syndrome, have antitumor and teratogenic effects through a mechanism involving destabilization of the CD147 and MCT1 proteins.",
"genre": "article",
"id": "sg:pub.10.1038/nm.4128",
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.2438898",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1113716",
"issn": [
"1078-8956",
"1546-170X"
],
"name": "Nature Medicine",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "7",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "22"
}
],
"keywords": [
"immunomodulatory drugs",
"multiple myeloma",
"myelodysplastic syndrome",
"derivative lenalidomide",
"teratogenic effects",
"antitumor activity",
"MCT1 protein",
"lenalidomide",
"myeloma",
"thalidomide",
"pomalidomide",
"syndrome",
"teratogenicity",
"CD147",
"drugs",
"antitumor",
"protein",
"activity",
"effect",
"mechanism",
"axis",
"destabilization"
],
"name": "Immunomodulatory drugs disrupt the cereblon\u2013CD147\u2013MCT1 axis to exert antitumor activity and teratogenicity",
"pagination": "735-743",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1016584456"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/nm.4128"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"27294876"
]
}
],
"sameAs": [
"https://doi.org/10.1038/nm.4128",
"https://app.dimensions.ai/details/publication/pub.1016584456"
],
"sdDataset": "articles",
"sdDatePublished": "2022-08-04T17:05",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/article/article_714.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/nm.4128"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/nm.4128'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/nm.4128'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/nm.4128'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/nm.4128'
This table displays all metadata directly associated to this object as RDF triples.
413 TRIPLES
21 PREDICATES
80 URIs
56 LITERALS
24 BLANK NODES