RNA editing enters the limelight in cancer View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2013-02

AUTHORS

Angela Gallo

ABSTRACT

There has been much focus on DNA mutations in tumorigenesis and tumor progression, but now a new study highlights a role for post-transcriptional changes in RNA in cancer. The authors show increased RNA editing of antizyme inhibitor 1 (AZIN1) in tumor tissues from patients with hepatocellular carcinoma and characterize a mechanism through which the expression of edited AZIN1 protein leads to increased cell proliferation (pages 209–216). More... »

PAGES

130

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/nm.3072

DOI

http://dx.doi.org/10.1038/nm.3072

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1009217082

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/23389604


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