2006-12
AUTHORSMatthew J Robinson, David Sancho, Emma C Slack, Salomé LeibundGut-Landmann, Caetano Reis e Sousa
ABSTRACTC-type lectins expressed on myeloid cells comprise a family of proteins that share a common structural motif, and some act as receptors in pathogen recognition. But just as the presence of leucine-rich repeats alone is not sufficient to define a Toll-like receptor, the characterization of C-type lectin receptors in innate immunity requires the identification of accompanying signaling motifs. Here we focus on the known signaling pathways of myeloid C-type lectins and on their possible functions as autonomous activating or inhibitory receptors involved in innate responses to pathogens or self. More... »
PAGES1258-1265
http://scigraph.springernature.com/pub.10.1038/ni1417
DOIhttp://dx.doi.org/10.1038/ni1417
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1018530461
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/17110942
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