Regulatory T cells in the control of immune pathology View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-09

AUTHORS

K J Maloy, F Powrie

ABSTRACT

It is now well established that regulatory T (T(R)) cells can inhibit harmful immunopathological responses directed against self or foreign antigens. However, many key aspects of T(R) cell biology remain unresolved, especially with regard to their antigen specificities and the cellular and molecular pathways involved in their development and mechanisms of action. We will review here recent findings in these areas, outline a model for how T(R) cells may inhibit the development of immune pathology and discuss potential therapeutic benefits that may arise from the manipulation of T(R) cell function. More... »

PAGES

816-822

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ni0901-816

DOI

http://dx.doi.org/10.1038/ni0901-816

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1027284442

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11526392


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