New tools for defining the 'genetic background' of inbred mouse strains View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2007-07

AUTHORS

William M Ridgway, Barry Healy, Luc J Smink, Dan Rainbow, Linda S Wicker

ABSTRACT

There is general appreciation that 'genetic background effects' can profoundly affect the immune phenotypes of congenic, transgenic and knockout mice. We suggest that attributing phenotypes to genetic background effects is outmoded and that new databases containing single-nucleotide polymorphisms obtained with a group of inbred mouse strains can be used to define the flanking DNA of nearly all mouse genes. More... »

PAGES

669-673

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ni0707-669

DOI

http://dx.doi.org/10.1038/ni0707-669

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1011121743

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/17579641


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