Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-09-28

AUTHORS

Jing Geng, Xiufeng Sun, Ping Wang, Shihao Zhang, Xiaozhen Wang, Hongtan Wu, Lixin Hong, Changchuan Xie, Xun Li, Hao Zhao, Qingxu Liu, Mingting Jiang, Qinghua Chen, Jinjia Zhang, Yang Li, Siyang Song, Hong-Rui Wang, Rongbin Zhou, Randy L Johnson, Kun-Yi Chien, Sheng-Cai Lin, Jiahuai Han, Joseph Avruch, Lanfen Chen, Dawang Zhou

ABSTRACT

Mitochondria must be juxtaposed to phagosomes to supply reactive oxygen species for effective killing of microbes. Zhou and colleagues demonstrate that the kinases Mst1 and Mst2 are important for controlling this redistribution of mitochondria.

PAGES

1142-1152

References to SciGraph publications

  • 2003-07-06. RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1 in NATURE IMMUNOLOGY
  • 2004-03. NOX enzymes and the biology of reactive oxygen in NATURE REVIEWS IMMUNOLOGY
  • 2004-09-07. Crucial functions of the Rap1 effector molecule RAPL in lymphocyte and dendritic cell trafficking in NATURE IMMUNOLOGY
  • 2011-12-09. The role of ubiquitylation in immune defence and pathogen evasion in NATURE REVIEWS IMMUNOLOGY
  • 2006-08-06. Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion in NATURE IMMUNOLOGY
  • 2012-01. Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus in NATURE COMMUNICATIONS
  • 2013-10-20. Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2 in NATURE MEDICINE
  • 2011-04-27. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS in NATURE
  • 2015-02-02. The kinase MST4 limits inflammatory responses through direct phosphorylation of the adaptor TRAF6 in NATURE IMMUNOLOGY
  • 2000-12. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production in NATURE GENETICS
  • 2009-09-20. CARD9 facilitates microbe-elicited production of reactive oxygen species by regulating the LyGDI-Rac1 complex in NATURE IMMUNOLOGY
  • 2013-03-07. The Hippo pathway and human cancer in NATURE REVIEWS CANCER
  • 2013-12-13. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment in NATURE REVIEWS DRUG DISCOVERY
  • Journal

    TITLE

    Nature Immunology

    ISSUE

    11

    VOLUME

    16

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ni.3268

    DOI

    http://dx.doi.org/10.1038/ni.3268

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1004835772

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26414765


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/11", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Medical and Health Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/1107", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Immunology", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Adaptor Proteins, Signal Transducing", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Animals", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Bacterial Infections", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Blood Bactericidal Activity", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Cell Line", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice, Inbred C57BL", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mice, Knockout", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Minor Histocompatibility Antigens", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Mitochondria", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phagocytes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phagosomes", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein Kinase C-alpha", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Protein Serine-Threonine Kinases", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Reactive Oxygen Species", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Sepsis", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Serine-Threonine Kinase 3", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Signal Transduction", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "TNF Receptor-Associated Factor 6", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Toll-Like Receptors", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Ubiquitination", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "rac GTP-Binding Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "rho Guanine Nucleotide Dissociation Inhibitor beta", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Geng", 
            "givenName": "Jing", 
            "id": "sg:person.01176223537.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176223537.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sun", 
            "givenName": "Xiufeng", 
            "id": "sg:person.01312452137.37", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312452137.37"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wang", 
            "givenName": "Ping", 
            "id": "sg:person.01212576232.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212576232.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhang", 
            "givenName": "Shihao", 
            "id": "sg:person.0745546537.85", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745546537.85"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wang", 
            "givenName": "Xiaozhen", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wu", 
            "givenName": "Hongtan", 
            "id": "sg:person.0747734052.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747734052.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hong", 
            "givenName": "Lixin", 
            "id": "sg:person.01102421330.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102421330.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Xie", 
            "givenName": "Changchuan", 
            "id": "sg:person.01000355135.45", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000355135.45"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Laboratory Medicine, the First Affiliated Hospital, Medical College of Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "Department of Laboratory Medicine, the First Affiliated Hospital, Medical College of Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Xun", 
            "id": "sg:person.01361756605.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361756605.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhao", 
            "givenName": "Hao", 
            "id": "sg:person.01042763102.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042763102.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Liu", 
            "givenName": "Qingxu", 
            "id": "sg:person.0734326347.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734326347.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Jiang", 
            "givenName": "Mingting", 
            "id": "sg:person.01314313370.38", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314313370.38"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chen", 
            "givenName": "Qinghua", 
            "id": "sg:person.01222010372.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222010372.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhang", 
            "givenName": "Jinjia", 
            "id": "sg:person.01043307672.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043307672.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Yang", 
            "id": "sg:person.0633312012.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633312012.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Song", 
            "givenName": "Siyang", 
            "id": "sg:person.01202064637.35", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202064637.35"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wang", 
            "givenName": "Hong-Rui", 
            "id": "sg:person.0600526654.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600526654.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China", 
              "id": "http://www.grid.ac/institutes/grid.59053.3a", 
              "name": [
                "Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhou", 
            "givenName": "Rongbin", 
            "id": "sg:person.01306124763.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306124763.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Biochemistry and Molecular Biology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "Department of Biochemistry and Molecular Biology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Johnson", 
            "givenName": "Randy L", 
            "id": "sg:person.0662371174.93", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662371174.93"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "College of Medicine, Chang Gung University, Kwei-Shan, Taiwan", 
              "id": "http://www.grid.ac/institutes/None", 
              "name": [
                "College of Medicine, Chang Gung University, Kwei-Shan, Taiwan"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chien", 
            "givenName": "Kun-Yi", 
            "id": "sg:person.01271027410.11", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271027410.11"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lin", 
            "givenName": "Sheng-Cai", 
            "id": "sg:person.011760475657.98", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011760475657.98"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Han", 
            "givenName": "Jiahuai", 
            "id": "sg:person.011242324437.61", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011242324437.61"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA", 
              "id": "http://www.grid.ac/institutes/grid.32224.35", 
              "name": [
                "Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA", 
                "Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Avruch", 
            "givenName": "Joseph", 
            "id": "sg:person.01074100404.77", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074100404.77"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chen", 
            "givenName": "Lanfen", 
            "id": "sg:person.01025212043.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025212043.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China", 
              "id": "http://www.grid.ac/institutes/grid.12955.3a", 
              "name": [
                "State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China"
              ], 
              "type": "Organization"
            }, 
            "familyName": "Zhou", 
            "givenName": "Dawang", 
            "id": "sg:person.01255667043.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255667043.25"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/ni.1788", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016565385", 
              "https://doi.org/10.1038/ni.1788"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/82565", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049529582", 
              "https://doi.org/10.1038/82565"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ncomms2105", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052405448", 
              "https://doi.org/10.1038/ncomms2105"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nm.3322", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040583506", 
              "https://doi.org/10.1038/nm.3322"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrc3458", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013461220", 
              "https://doi.org/10.1038/nrc3458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri3111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015695778", 
              "https://doi.org/10.1038/nri3111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni.3097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000676336", 
              "https://doi.org/10.1038/ni.3097"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1374", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046395705", 
              "https://doi.org/10.1038/ni1374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri1312", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031022953", 
              "https://doi.org/10.1038/nri1312"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni950", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042647979", 
              "https://doi.org/10.1038/ni950"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ni1111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043204699", 
              "https://doi.org/10.1038/ni1111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrd4161", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006047977", 
              "https://doi.org/10.1038/nrd4161"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09973", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031751414", 
              "https://doi.org/10.1038/nature09973"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2015-09-28", 
        "datePublishedReg": "2015-09-28", 
        "description": "Mitochondria must be juxtaposed to phagosomes to supply reactive oxygen species for effective killing of microbes. Zhou and colleagues demonstrate that the kinases Mst1 and Mst2 are important for controlling this redistribution of mitochondria.", 
        "genre": "article", 
        "id": "sg:pub.10.1038/ni.3268", 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2438826", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2480107", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8342190", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2439026", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8338939", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8329976", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8333980", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.9710467", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8379847", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.8377466", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.7191604", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.7189502", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1022778", 
            "issn": [
              "1529-2908", 
              "1529-2916"
            ], 
            "name": "Nature Immunology", 
            "publisher": "Springer Nature", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "11", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "16"
          }
        ], 
        "keywords": [
          "kinase Mst1", 
          "reactive oxygen species", 
          "redistribution of mitochondria", 
          "oxygen species", 
          "MST2", 
          "MST1", 
          "mitochondria", 
          "species", 
          "microbes", 
          "phagosomes", 
          "effective killing", 
          "induction", 
          "bactericidal activity", 
          "killing", 
          "activity", 
          "redistribution", 
          "Zhou", 
          "colleagues"
        ], 
        "name": "Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity", 
        "pagination": "1142-1152", 
        "productId": [
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1004835772"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ni.3268"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "26414765"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ni.3268", 
          "https://app.dimensions.ai/details/publication/pub.1004835772"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2022-09-02T15:58", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-springernature-scigraph/baseset/20220902/entities/gbq_results/article/article_657.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://doi.org/10.1038/ni.3268"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ni.3268'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ni.3268'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ni.3268'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ni.3268'


     

    This table displays all metadata directly associated to this object as RDF triples.

    432 TRIPLES      21 PREDICATES      80 URIs      59 LITERALS      31 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ni.3268 schema:about N08161d5415894bf5800c052bc759fea5
    2 N13f628cdd73247f3bba3ad9e80f98281
    3 N2cfa9aa1d6f54a299ac12c42c07dc5f6
    4 N2f2bc95912524b4da17282b2386f71c1
    5 N32e0902035fa4f02ad6e8d33520e5c07
    6 N3b55ed079a684d4cb612f2cd5d66390e
    7 N637306dcdf2f4818a3d113a1ba67ea66
    8 N6909db50eeda45169aa39cc76e0375ff
    9 N6f37b634a655463dacba3276a8fb2849
    10 N78e4b112e8e84669adc291351d270c34
    11 N7e11377b5cc44445a8077bdd40b83214
    12 N84d7e18d320f4e4fb49293d8706236d3
    13 Na0084f0fd53340c788bbd091f3b882d7
    14 Na2be446fa4334b28988b4b2a7aec94b0
    15 Na40c4b09468f445eb58c13bd01f18b0c
    16 Nb7ee6ad269b041508857ec400e29b343
    17 Nbe64b317f0334c3cbefdd7ff2e13f5f1
    18 Nc56bd80fa9fc48a2bca5a631429157bc
    19 Nc63dc79eb1f941c18b9930b45a8f2c67
    20 Nd56e19547e0943ddbba13b6f748f9da4
    21 Nd6380d4b2bbe4a1ab4db0faa79048774
    22 Ne1e8533b483d41298e9ab71bb1618d41
    23 Ne86d30d01ca1457cb381ecb739ff1f7f
    24 Ne9182575ba6e43a7a181bf21db5ab6be
    25 anzsrc-for:11
    26 anzsrc-for:1107
    27 schema:author Nd0725d0f55864d9fb1e79ce56d5bf51d
    28 schema:citation sg:pub.10.1038/82565
    29 sg:pub.10.1038/nature09973
    30 sg:pub.10.1038/ncomms2105
    31 sg:pub.10.1038/ni.1788
    32 sg:pub.10.1038/ni.3097
    33 sg:pub.10.1038/ni1111
    34 sg:pub.10.1038/ni1374
    35 sg:pub.10.1038/ni950
    36 sg:pub.10.1038/nm.3322
    37 sg:pub.10.1038/nrc3458
    38 sg:pub.10.1038/nrd4161
    39 sg:pub.10.1038/nri1312
    40 sg:pub.10.1038/nri3111
    41 schema:datePublished 2015-09-28
    42 schema:datePublishedReg 2015-09-28
    43 schema:description Mitochondria must be juxtaposed to phagosomes to supply reactive oxygen species for effective killing of microbes. Zhou and colleagues demonstrate that the kinases Mst1 and Mst2 are important for controlling this redistribution of mitochondria.
    44 schema:genre article
    45 schema:isAccessibleForFree true
    46 schema:isPartOf N9d8235e5166947d3a394af8a2807c01b
    47 Nabfe477ce6ac4cd2bfbe8be1db61f3c3
    48 sg:journal.1022778
    49 schema:keywords MST1
    50 MST2
    51 Zhou
    52 activity
    53 bactericidal activity
    54 colleagues
    55 effective killing
    56 induction
    57 killing
    58 kinase Mst1
    59 microbes
    60 mitochondria
    61 oxygen species
    62 phagosomes
    63 reactive oxygen species
    64 redistribution
    65 redistribution of mitochondria
    66 species
    67 schema:name Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity
    68 schema:pagination 1142-1152
    69 schema:productId N2dc1c4da40b544539f3ac1f0efa8e57f
    70 N50300eeda93b4a7282a1cbdd30c685d8
    71 Nc63222bac0754d4cabcf4135f536c3b8
    72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004835772
    73 https://doi.org/10.1038/ni.3268
    74 schema:sdDatePublished 2022-09-02T15:58
    75 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    76 schema:sdPublisher Na0da357fa04e4918bb4298f8067ed84f
    77 schema:url https://doi.org/10.1038/ni.3268
    78 sgo:license sg:explorer/license/
    79 sgo:sdDataset articles
    80 rdf:type schema:ScholarlyArticle
    81 N0606c222d07c411881cc68259f4f6272 rdf:first sg:person.0662371174.93
    82 rdf:rest N98e789873408476baa8232cd2f53722a
    83 N06d3f8ee46a14e4f923e800f346842b5 rdf:first sg:person.01042763102.18
    84 rdf:rest N38a44a4b31224cd29d3bfdb07f5acf93
    85 N08161d5415894bf5800c052bc759fea5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    86 schema:name rac GTP-Binding Proteins
    87 rdf:type schema:DefinedTerm
    88 N0eca5685159a448ea3d31bd0431348f9 rdf:first sg:person.01212576232.51
    89 rdf:rest Nce15aebe04214e8fbf71902e5917adf0
    90 N13f628cdd73247f3bba3ad9e80f98281 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    91 schema:name Serine-Threonine Kinase 3
    92 rdf:type schema:DefinedTerm
    93 N15bfcb1016c24907a191fff0efb2b0d2 schema:affiliation grid-institutes:grid.12955.3a
    94 schema:familyName Wang
    95 schema:givenName Xiaozhen
    96 rdf:type schema:Person
    97 N2cfa9aa1d6f54a299ac12c42c07dc5f6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    98 schema:name Sepsis
    99 rdf:type schema:DefinedTerm
    100 N2dc1c4da40b544539f3ac1f0efa8e57f schema:name doi
    101 schema:value 10.1038/ni.3268
    102 rdf:type schema:PropertyValue
    103 N2f2bc95912524b4da17282b2386f71c1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    104 schema:name Adaptor Proteins, Signal Transducing
    105 rdf:type schema:DefinedTerm
    106 N32e0902035fa4f02ad6e8d33520e5c07 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    107 schema:name Phagocytes
    108 rdf:type schema:DefinedTerm
    109 N38a44a4b31224cd29d3bfdb07f5acf93 rdf:first sg:person.0734326347.13
    110 rdf:rest Nabc69e5d4a744aab90444f944ae86c3f
    111 N3b55ed079a684d4cb612f2cd5d66390e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    112 schema:name Signal Transduction
    113 rdf:type schema:DefinedTerm
    114 N50300eeda93b4a7282a1cbdd30c685d8 schema:name dimensions_id
    115 schema:value pub.1004835772
    116 rdf:type schema:PropertyValue
    117 N5568130da2ee4b9b9cf23059e1c0fef6 rdf:first sg:person.01306124763.02
    118 rdf:rest N0606c222d07c411881cc68259f4f6272
    119 N5efac0efacf34ff3bd13ca20bdb76d6e rdf:first sg:person.011760475657.98
    120 rdf:rest N741c1e6ece614f7bbf11c12f1bc33cf0
    121 N6266a5232bdf4235a7eb442113aa7164 rdf:first sg:person.0747734052.53
    122 rdf:rest N7291d22877744363906dbcdf24791c25
    123 N637306dcdf2f4818a3d113a1ba67ea66 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    124 schema:name rho Guanine Nucleotide Dissociation Inhibitor beta
    125 rdf:type schema:DefinedTerm
    126 N6909db50eeda45169aa39cc76e0375ff schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    127 schema:name Mitochondria
    128 rdf:type schema:DefinedTerm
    129 N697f9f9e2ddd424f9821cd61cdb90043 rdf:first sg:person.01074100404.77
    130 rdf:rest Ncd67609283404577946836ec3ef5c945
    131 N6b3433c5b9e04a9f9db0c1c2b10bd3ab rdf:first sg:person.01222010372.74
    132 rdf:rest N85a370114aed418da640085742cce5fe
    133 N6f37b634a655463dacba3276a8fb2849 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    134 schema:name Protein Serine-Threonine Kinases
    135 rdf:type schema:DefinedTerm
    136 N7291d22877744363906dbcdf24791c25 rdf:first sg:person.01102421330.05
    137 rdf:rest N9ae2b440ecde437a92922c1755fca2be
    138 N741c1e6ece614f7bbf11c12f1bc33cf0 rdf:first sg:person.011242324437.61
    139 rdf:rest N697f9f9e2ddd424f9821cd61cdb90043
    140 N78e4b112e8e84669adc291351d270c34 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    141 schema:name Toll-Like Receptors
    142 rdf:type schema:DefinedTerm
    143 N796ac481efb748b2a921831722ffa966 rdf:first sg:person.01255667043.25
    144 rdf:rest rdf:nil
    145 N7d2463703a654d0d8f8b47bca30eb622 rdf:first N15bfcb1016c24907a191fff0efb2b0d2
    146 rdf:rest N6266a5232bdf4235a7eb442113aa7164
    147 N7e11377b5cc44445a8077bdd40b83214 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    148 schema:name Ubiquitination
    149 rdf:type schema:DefinedTerm
    150 N84d7e18d320f4e4fb49293d8706236d3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    151 schema:name Blood Bactericidal Activity
    152 rdf:type schema:DefinedTerm
    153 N85a370114aed418da640085742cce5fe rdf:first sg:person.01043307672.82
    154 rdf:rest Nd207f53a2b20437f8a6123efa66ce36f
    155 N88068ce8886e49b1a101556bbf8b337f rdf:first sg:person.01312452137.37
    156 rdf:rest N0eca5685159a448ea3d31bd0431348f9
    157 N98e789873408476baa8232cd2f53722a rdf:first sg:person.01271027410.11
    158 rdf:rest N5efac0efacf34ff3bd13ca20bdb76d6e
    159 N9ae2b440ecde437a92922c1755fca2be rdf:first sg:person.01000355135.45
    160 rdf:rest Nfaadb2de7d6e4e4c889ec22bdabf79aa
    161 N9d8235e5166947d3a394af8a2807c01b schema:issueNumber 11
    162 rdf:type schema:PublicationIssue
    163 Na0084f0fd53340c788bbd091f3b882d7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    164 schema:name TNF Receptor-Associated Factor 6
    165 rdf:type schema:DefinedTerm
    166 Na0da357fa04e4918bb4298f8067ed84f schema:name Springer Nature - SN SciGraph project
    167 rdf:type schema:Organization
    168 Na2be446fa4334b28988b4b2a7aec94b0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    169 schema:name Mice
    170 rdf:type schema:DefinedTerm
    171 Na40c4b09468f445eb58c13bd01f18b0c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    172 schema:name Bacterial Infections
    173 rdf:type schema:DefinedTerm
    174 Na850a3a0f7114699a92be3f31a85cb92 rdf:first sg:person.0600526654.81
    175 rdf:rest N5568130da2ee4b9b9cf23059e1c0fef6
    176 Nab920e512b504d418bdcda687866cc98 rdf:first sg:person.01202064637.35
    177 rdf:rest Na850a3a0f7114699a92be3f31a85cb92
    178 Nabc69e5d4a744aab90444f944ae86c3f rdf:first sg:person.01314313370.38
    179 rdf:rest N6b3433c5b9e04a9f9db0c1c2b10bd3ab
    180 Nabfe477ce6ac4cd2bfbe8be1db61f3c3 schema:volumeNumber 16
    181 rdf:type schema:PublicationVolume
    182 Nb7ee6ad269b041508857ec400e29b343 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    183 schema:name Reactive Oxygen Species
    184 rdf:type schema:DefinedTerm
    185 Nbe64b317f0334c3cbefdd7ff2e13f5f1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    186 schema:name Animals
    187 rdf:type schema:DefinedTerm
    188 Nc56bd80fa9fc48a2bca5a631429157bc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    189 schema:name Cell Line
    190 rdf:type schema:DefinedTerm
    191 Nc63222bac0754d4cabcf4135f536c3b8 schema:name pubmed_id
    192 schema:value 26414765
    193 rdf:type schema:PropertyValue
    194 Nc63dc79eb1f941c18b9930b45a8f2c67 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    195 schema:name Humans
    196 rdf:type schema:DefinedTerm
    197 Ncd67609283404577946836ec3ef5c945 rdf:first sg:person.01025212043.29
    198 rdf:rest N796ac481efb748b2a921831722ffa966
    199 Nce15aebe04214e8fbf71902e5917adf0 rdf:first sg:person.0745546537.85
    200 rdf:rest N7d2463703a654d0d8f8b47bca30eb622
    201 Nd0725d0f55864d9fb1e79ce56d5bf51d rdf:first sg:person.01176223537.09
    202 rdf:rest N88068ce8886e49b1a101556bbf8b337f
    203 Nd207f53a2b20437f8a6123efa66ce36f rdf:first sg:person.0633312012.24
    204 rdf:rest Nab920e512b504d418bdcda687866cc98
    205 Nd56e19547e0943ddbba13b6f748f9da4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    206 schema:name Mice, Knockout
    207 rdf:type schema:DefinedTerm
    208 Nd6380d4b2bbe4a1ab4db0faa79048774 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    209 schema:name Phagosomes
    210 rdf:type schema:DefinedTerm
    211 Ne1e8533b483d41298e9ab71bb1618d41 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    212 schema:name Mice, Inbred C57BL
    213 rdf:type schema:DefinedTerm
    214 Ne86d30d01ca1457cb381ecb739ff1f7f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    215 schema:name Minor Histocompatibility Antigens
    216 rdf:type schema:DefinedTerm
    217 Ne9182575ba6e43a7a181bf21db5ab6be schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    218 schema:name Protein Kinase C-alpha
    219 rdf:type schema:DefinedTerm
    220 Nfaadb2de7d6e4e4c889ec22bdabf79aa rdf:first sg:person.01361756605.64
    221 rdf:rest N06d3f8ee46a14e4f923e800f346842b5
    222 anzsrc-for:11 schema:inDefinedTermSet anzsrc-for:
    223 schema:name Medical and Health Sciences
    224 rdf:type schema:DefinedTerm
    225 anzsrc-for:1107 schema:inDefinedTermSet anzsrc-for:
    226 schema:name Immunology
    227 rdf:type schema:DefinedTerm
    228 sg:grant.2438826 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    229 rdf:type schema:MonetaryGrant
    230 sg:grant.2439026 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    231 rdf:type schema:MonetaryGrant
    232 sg:grant.2480107 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    233 rdf:type schema:MonetaryGrant
    234 sg:grant.7189502 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    235 rdf:type schema:MonetaryGrant
    236 sg:grant.7191604 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    237 rdf:type schema:MonetaryGrant
    238 sg:grant.8329976 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    239 rdf:type schema:MonetaryGrant
    240 sg:grant.8333980 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    241 rdf:type schema:MonetaryGrant
    242 sg:grant.8338939 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    243 rdf:type schema:MonetaryGrant
    244 sg:grant.8342190 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    245 rdf:type schema:MonetaryGrant
    246 sg:grant.8377466 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    247 rdf:type schema:MonetaryGrant
    248 sg:grant.8379847 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    249 rdf:type schema:MonetaryGrant
    250 sg:grant.9710467 http://pending.schema.org/fundedItem sg:pub.10.1038/ni.3268
    251 rdf:type schema:MonetaryGrant
    252 sg:journal.1022778 schema:issn 1529-2908
    253 1529-2916
    254 schema:name Nature Immunology
    255 schema:publisher Springer Nature
    256 rdf:type schema:Periodical
    257 sg:person.01000355135.45 schema:affiliation grid-institutes:grid.12955.3a
    258 schema:familyName Xie
    259 schema:givenName Changchuan
    260 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01000355135.45
    261 rdf:type schema:Person
    262 sg:person.01025212043.29 schema:affiliation grid-institutes:grid.12955.3a
    263 schema:familyName Chen
    264 schema:givenName Lanfen
    265 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01025212043.29
    266 rdf:type schema:Person
    267 sg:person.01042763102.18 schema:affiliation grid-institutes:grid.12955.3a
    268 schema:familyName Zhao
    269 schema:givenName Hao
    270 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01042763102.18
    271 rdf:type schema:Person
    272 sg:person.01043307672.82 schema:affiliation grid-institutes:grid.12955.3a
    273 schema:familyName Zhang
    274 schema:givenName Jinjia
    275 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01043307672.82
    276 rdf:type schema:Person
    277 sg:person.01074100404.77 schema:affiliation grid-institutes:grid.32224.35
    278 schema:familyName Avruch
    279 schema:givenName Joseph
    280 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074100404.77
    281 rdf:type schema:Person
    282 sg:person.01102421330.05 schema:affiliation grid-institutes:grid.12955.3a
    283 schema:familyName Hong
    284 schema:givenName Lixin
    285 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102421330.05
    286 rdf:type schema:Person
    287 sg:person.011242324437.61 schema:affiliation grid-institutes:grid.12955.3a
    288 schema:familyName Han
    289 schema:givenName Jiahuai
    290 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011242324437.61
    291 rdf:type schema:Person
    292 sg:person.011760475657.98 schema:affiliation grid-institutes:grid.12955.3a
    293 schema:familyName Lin
    294 schema:givenName Sheng-Cai
    295 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011760475657.98
    296 rdf:type schema:Person
    297 sg:person.01176223537.09 schema:affiliation grid-institutes:grid.12955.3a
    298 schema:familyName Geng
    299 schema:givenName Jing
    300 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01176223537.09
    301 rdf:type schema:Person
    302 sg:person.01202064637.35 schema:affiliation grid-institutes:grid.12955.3a
    303 schema:familyName Song
    304 schema:givenName Siyang
    305 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202064637.35
    306 rdf:type schema:Person
    307 sg:person.01212576232.51 schema:affiliation grid-institutes:grid.12955.3a
    308 schema:familyName Wang
    309 schema:givenName Ping
    310 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212576232.51
    311 rdf:type schema:Person
    312 sg:person.01222010372.74 schema:affiliation grid-institutes:grid.12955.3a
    313 schema:familyName Chen
    314 schema:givenName Qinghua
    315 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222010372.74
    316 rdf:type schema:Person
    317 sg:person.01255667043.25 schema:affiliation grid-institutes:grid.12955.3a
    318 schema:familyName Zhou
    319 schema:givenName Dawang
    320 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255667043.25
    321 rdf:type schema:Person
    322 sg:person.01271027410.11 schema:affiliation grid-institutes:None
    323 schema:familyName Chien
    324 schema:givenName Kun-Yi
    325 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01271027410.11
    326 rdf:type schema:Person
    327 sg:person.01306124763.02 schema:affiliation grid-institutes:grid.59053.3a
    328 schema:familyName Zhou
    329 schema:givenName Rongbin
    330 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01306124763.02
    331 rdf:type schema:Person
    332 sg:person.01312452137.37 schema:affiliation grid-institutes:grid.12955.3a
    333 schema:familyName Sun
    334 schema:givenName Xiufeng
    335 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312452137.37
    336 rdf:type schema:Person
    337 sg:person.01314313370.38 schema:affiliation grid-institutes:grid.12955.3a
    338 schema:familyName Jiang
    339 schema:givenName Mingting
    340 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314313370.38
    341 rdf:type schema:Person
    342 sg:person.01361756605.64 schema:affiliation grid-institutes:grid.12955.3a
    343 schema:familyName Li
    344 schema:givenName Xun
    345 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01361756605.64
    346 rdf:type schema:Person
    347 sg:person.0600526654.81 schema:affiliation grid-institutes:grid.12955.3a
    348 schema:familyName Wang
    349 schema:givenName Hong-Rui
    350 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0600526654.81
    351 rdf:type schema:Person
    352 sg:person.0633312012.24 schema:affiliation grid-institutes:grid.12955.3a
    353 schema:familyName Li
    354 schema:givenName Yang
    355 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0633312012.24
    356 rdf:type schema:Person
    357 sg:person.0662371174.93 schema:affiliation grid-institutes:None
    358 schema:familyName Johnson
    359 schema:givenName Randy L
    360 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0662371174.93
    361 rdf:type schema:Person
    362 sg:person.0734326347.13 schema:affiliation grid-institutes:grid.12955.3a
    363 schema:familyName Liu
    364 schema:givenName Qingxu
    365 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0734326347.13
    366 rdf:type schema:Person
    367 sg:person.0745546537.85 schema:affiliation grid-institutes:grid.12955.3a
    368 schema:familyName Zhang
    369 schema:givenName Shihao
    370 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745546537.85
    371 rdf:type schema:Person
    372 sg:person.0747734052.53 schema:affiliation grid-institutes:grid.12955.3a
    373 schema:familyName Wu
    374 schema:givenName Hongtan
    375 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0747734052.53
    376 rdf:type schema:Person
    377 sg:pub.10.1038/82565 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049529582
    378 https://doi.org/10.1038/82565
    379 rdf:type schema:CreativeWork
    380 sg:pub.10.1038/nature09973 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031751414
    381 https://doi.org/10.1038/nature09973
    382 rdf:type schema:CreativeWork
    383 sg:pub.10.1038/ncomms2105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052405448
    384 https://doi.org/10.1038/ncomms2105
    385 rdf:type schema:CreativeWork
    386 sg:pub.10.1038/ni.1788 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016565385
    387 https://doi.org/10.1038/ni.1788
    388 rdf:type schema:CreativeWork
    389 sg:pub.10.1038/ni.3097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000676336
    390 https://doi.org/10.1038/ni.3097
    391 rdf:type schema:CreativeWork
    392 sg:pub.10.1038/ni1111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043204699
    393 https://doi.org/10.1038/ni1111
    394 rdf:type schema:CreativeWork
    395 sg:pub.10.1038/ni1374 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046395705
    396 https://doi.org/10.1038/ni1374
    397 rdf:type schema:CreativeWork
    398 sg:pub.10.1038/ni950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042647979
    399 https://doi.org/10.1038/ni950
    400 rdf:type schema:CreativeWork
    401 sg:pub.10.1038/nm.3322 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040583506
    402 https://doi.org/10.1038/nm.3322
    403 rdf:type schema:CreativeWork
    404 sg:pub.10.1038/nrc3458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013461220
    405 https://doi.org/10.1038/nrc3458
    406 rdf:type schema:CreativeWork
    407 sg:pub.10.1038/nrd4161 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006047977
    408 https://doi.org/10.1038/nrd4161
    409 rdf:type schema:CreativeWork
    410 sg:pub.10.1038/nri1312 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031022953
    411 https://doi.org/10.1038/nri1312
    412 rdf:type schema:CreativeWork
    413 sg:pub.10.1038/nri3111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015695778
    414 https://doi.org/10.1038/nri3111
    415 rdf:type schema:CreativeWork
    416 grid-institutes:None schema:alternateName College of Medicine, Chang Gung University, Kwei-Shan, Taiwan
    417 Department of Biochemistry and Molecular Biology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA
    418 schema:name College of Medicine, Chang Gung University, Kwei-Shan, Taiwan
    419 Department of Biochemistry and Molecular Biology, University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA
    420 rdf:type schema:Organization
    421 grid-institutes:grid.12955.3a schema:alternateName Department of Laboratory Medicine, the First Affiliated Hospital, Medical College of Xiamen University, Xiamen, China
    422 State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China
    423 schema:name Department of Laboratory Medicine, the First Affiliated Hospital, Medical College of Xiamen University, Xiamen, China
    424 State Key Laboratory of Cellular Stress Biology, Innovation Center for Cell Signaling Network, School of Life Sciences, Xiamen University, Xiamen, China
    425 rdf:type schema:Organization
    426 grid-institutes:grid.32224.35 schema:alternateName Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA
    427 schema:name Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
    428 Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA
    429 rdf:type schema:Organization
    430 grid-institutes:grid.59053.3a schema:alternateName Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China
    431 schema:name Institute of Immunology and the CAS Key Laboratory of Innate Immunity and Chronic Disease, Innovation Center for Cell Signaling Network, School of Life Sciences and Medical Center, University of Science and Technology of China, Hefei, China
    432 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...