Batf3 maintains autoactivation of Irf8 for commitment of a CD8α+ conventional DC clonogenic progenitor View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-07

AUTHORS

Gary E Grajales-Reyes, Arifumi Iwata, Jörn Albring, Xiaodi Wu, Roxane Tussiwand, Wumesh Kc, Nicole M Kretzer, Carlos G Briseño, Vivek Durai, Prachi Bagadia, Malay Haldar, Jörg Schönheit, Frank Rosenbauer, Theresa L Murphy, Kenneth M Murphy

ABSTRACT

The transcription factors Batf3 and IRF8 are required for the development of CD8α(+) conventional dendritic cells (cDCs), but the basis for their actions has remained unclear. Here we identified two progenitor cells positive for the transcription factor Zbtb46 that separately generated CD8α(+) cDCs and CD4(+) cDCs and arose directly from the common DC progenitor (CDP). Irf8 expression in CDPs required prior autoactivation of Irf8 that was dependent on the transcription factor PU.1. Specification of the clonogenic progenitor of CD8α(+) cDCs (the pre-CD8 DC) required IRF8 but not Batf3. However, after specification of pre-CD8 DCs, autoactivation of Irf8 became Batf3 dependent at a CD8α(+) cDC-specific enhancer with multiple transcription factor AP1-IRF composite elements (AICEs) within the Irf8 superenhancer. CDPs from Batf3(-/-) mice that were specified toward development into pre-CD8 DCs failed to complete their development into CD8α(+) cDCs due to decay of Irf8 autoactivation and diverted to the CD4(+) cDC lineage. More... »

PAGES

708-717

References to SciGraph publications

  • 2006-06. Intrasplenic steady-state dendritic cell precursors that are distinct from monocytes in NATURE IMMUNOLOGY
  • 2009-03. Ultrafast and memory-efficient alignment of short DNA sequences to the human genome in GENOME BIOLOGY
  • 2008-11. Model-based Analysis of ChIP-Seq (MACS) in GENOME BIOLOGY
  • 2009-07. The AP-1 transcription factor Batf controls TH17 differentiation in NATURE
  • 2014-02. Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation in NATURE IMMUNOLOGY
  • 2014-02-09. L-Myc expression by dendritic cells is required for optimal T-cell priming in NATURE
  • 2011-08. Plasmacytoid dendritic cells: one-trick ponies or workhorses of the immune system? in NATURE REVIEWS IMMUNOLOGY
  • 2012-09. An integrated encyclopedia of DNA elements in the human genome in NATURE
  • 2012-12. Re(de)fining the dendritic cell lineage in NATURE IMMUNOLOGY
  • 2007-07. Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major in NATURE MEDICINE
  • 2007-11. Dendritic cell genealogy: a new stem or just another branch? in NATURE IMMUNOLOGY
  • 2011-06. The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells in NATURE IMMUNOLOGY
  • 2007-11. Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo in NATURE IMMUNOLOGY
  • 2007-11. Identification of clonogenic common Flt3+M-CSFR+ plasmacytoid and conventional dendritic cell progenitors in mouse bone marrow in NATURE IMMUNOLOGY
  • 2003-04. Transcriptional profiling identifies Id2 function in dendritic cell development in NATURE IMMUNOLOGY
  • 2012-09-19. Compensatory dendritic cell development mediated by BATF–IRF interactions in NATURE
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ni.3197

    DOI

    http://dx.doi.org/10.1038/ni.3197

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1003497682

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26054719


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