The carboxypeptidase ACE shapes the MHC class I peptide repertoire View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-10-02

AUTHORS

Xiao Z Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron E Lukacher, Kenneth E Bernstein

ABSTRACT

Production of MHC class I epitopes involves the proteasome and multiple peptidases. Bernstein and colleagues show that angiotensin-converting enzyme (ACE) contributes to the generation of this peptide repertoire by trimming carboxyl termini.

PAGES

1078-1085

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ni.2107

DOI

http://dx.doi.org/10.1038/ni.2107

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1048684442

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/21964607


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