Influence of the transcription factor RORγt on the development of NKp46+ cell populations in gut and skin View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-01

AUTHORS

Carmelo Luci, Ana Reynders, Ivaylo I Ivanov, Celine Cognet, Laurent Chiche, Lionel Chasson, Jean Hardwigsen, Esperanza Anguiano, Jacques Banchereau, Damien Chaussabel, Marc Dalod, Dan R Littman, Eric Vivier, Elena Tomasello

ABSTRACT

NKp46+CD3- natural killer lymphocytes isolated from blood, lymphoid organs, lung, liver and uterus can produce granule-dependent cytotoxicity and interferon-gamma. Here we identify in dermis, gut lamina propria and cryptopatches distinct populations of NKp46+CD3- cells with a diminished capacity to degranulate and produce interferon-gamma. In the gut, expression of the transcription factor RORgammat, which is involved in the development of lymphoid tissue-inducer cells, defined a previously unknown subset of NKp46+CD3- lymphocytes. Unlike RORgammat- lamina propria and dermis natural killer cells, gut RORgammat+NKp46+ cells produced interleukin 22. Our data show that lymphoid tissue-inducer cells and natural killer cells shared unanticipated similarities and emphasize the heterogeneity of NKp46+CD3- cells in innate immunity, lymphoid organization and local tissue repair. More... »

PAGES

75-82

References to SciGraph publications

  • 2003-12. Immunopathologic Features of Allergic Contact Dermatitis in Humans: Participation of Plasmacytoid Dendritic Cells in the Pathogenesis of the Disease? in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2002-10. Natural Killer and Dendritic Cell Contact in Lesional Atopic Dermatitis Skin –Malassezia-Influenced Cell Interaction in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • 2006-11. A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127 in NATURE IMMUNOLOGY
  • 2003-04. Anatomical basis of tolerance and immunity to intestinal antigens in NATURE REVIEWS IMMUNOLOGY
  • 2006-05. T cell– and B cell–independent adaptive immunity mediated by natural killer cells in NATURE IMMUNOLOGY
  • 2008-05-08. TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function in NATURE
  • 1999-02. Development of peripheral lymphoid organs and natural killer cells depends on the helix–loop–helix inhibitor Id2 in NATURE
  • 2005-05. Inducible lymphoid tissues in the adult gut: recapitulation of a fetal developmental pathway? in NATURE REVIEWS IMMUNOLOGY
  • 2008-05. TH17 cells in development: an updated view of their molecular identity and genetic programming in NATURE REVIEWS IMMUNOLOGY
  • 2001-02. Recognition of haemagglutinins on virus-infected cells by NKp46 activates lysis by human NK cells in NATURE
  • 2008-05. Functions of natural killer cells in NATURE IMMUNOLOGY
  • 2008-06. Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone in NATURE IMMUNOLOGY
  • 2002-06. In vivo developmental stages in murine natural killer cell maturation in NATURE IMMUNOLOGY
  • 2004-03. Immune surveillance in the skin: mechanisms and clinical consequences in NATURE REVIEWS IMMUNOLOGY
  • 2006-05. Lethal influenza infection in the absence of the natural killer cell receptor gene Ncr1 in NATURE IMMUNOLOGY
  • 2008-03. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens in NATURE MEDICINE
  • 2009-01. RORγt and commensal microflora are required for the differentiation of mucosal interleukin 22–producing NKp46+ cells in NATURE IMMUNOLOGY
  • 2008-03. IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia in NATURE MEDICINE
  • 2009-01. Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells in NATURE IMMUNOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ni.1681

    DOI

    http://dx.doi.org/10.1038/ni.1681

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1020550984

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19029904


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