Small changes in expression affect predisposition to tumorigenesis View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2002-01

AUTHORS

Hai Yan, Zuzana Dobbie, Stephen B Gruber, Sanford Markowitz, Kathy Romans, Francis M Giardiello, Kenneth W Kinzler, Bert Vogelstein

ABSTRACT

We have used quantitative measures of gene expression to show that constitutional 50% decreases in expression of one adenomatous polyposis coli tumor suppressor gene (APC) allele can lead to the development of familial adenomatous polyposis.

PAGES

25-26

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng799

DOI

http://dx.doi.org/10.1038/ng799

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1035982266

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11743581


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