The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-11

AUTHORS

T Kuroda-Kawaguchi, H Skaletsky, L G Brown, P J Minx, H S Cordum, R H Waterston, R K Wilson, S Silber, R Oates, S Rozen, D C Page

ABSTRACT

Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the most common known cause of spermatogenic failure. We determined the complete nucleotide sequence of AZFc by identifying and distinguishing between near-identical amplicons (massive repeat units) using an iterative mapping-sequencing process. A complex of three palindromes, the largest spanning 3 Mb with 99.97% identity between its arms, encompasses the AZFc region. The palindromes are constructed from six distinct families of amplicons, with unit lengths of 115-678 kb, and may have resulted from tandem duplication and inversion during primate evolution. The palindromic complex contains 11 families of transcription units, all expressed in testis. Deletions of AZFc that cause infertility are remarkably uniform, spanning a 3.5-Mb segment and bounded by 229-kb direct repeats that probably served as substrates for homologous recombination. More... »

PAGES

279-286

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng757

DOI

http://dx.doi.org/10.1038/ng757

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1040986528

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/11687796


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Base Sequence", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Deletion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Inversion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 3", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Deleted in Azoospermia 1 Protein", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Evolution, Molecular", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Duplication", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Infertility, Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Models, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Sequence Data", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Oligospermia", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Organ Specificity", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Physical Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "RNA-Binding Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Recombination, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Deletion", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Homology, Nucleic Acid", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Spermatozoa", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tandem Repeat Sequences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Testis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription, Genetic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Y Chromosome", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Howard Hughes Medical Institute", 
          "id": "https://www.grid.ac/institutes/grid.413575.1", 
          "name": [
            "Howard Hughes Medical Institute, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kuroda-Kawaguchi", 
        "givenName": "T", 
        "id": "sg:person.0702641052.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702641052.21"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Skaletsky", 
        "givenName": "H", 
        "id": "sg:person.01266753034.97", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266753034.97"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Brown", 
        "givenName": "L G", 
        "id": "sg:person.012271742572.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012271742572.52"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Minx", 
        "givenName": "P J", 
        "type": "Person"
      }, 
      {
        "familyName": "Cordum", 
        "givenName": "H S", 
        "id": "sg:person.01017067452.18", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017067452.18"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Waterston", 
        "givenName": "R H", 
        "id": "sg:person.0772724136.39", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772724136.39"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Wilson", 
        "givenName": "R K", 
        "id": "sg:person.013076541047.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013076541047.38"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Silber", 
        "givenName": "S", 
        "id": "sg:person.01270344172.00", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270344172.00"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Oates", 
        "givenName": "R", 
        "id": "sg:person.01111611776.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111611776.37"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Rozen", 
        "givenName": "S", 
        "id": "sg:person.013130175037.28", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013130175037.28"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Page", 
        "givenName": "D C", 
        "id": "sg:person.01224407762.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224407762.64"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1093/hmg/8.7.1177", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000300808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0015-0282(97)80083-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004328031"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/bmj.291.6510.1693", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005990102"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000185175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009783130"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1196-292", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012147825", 
          "https://doi.org/10.1038/ng1196-292"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(05)80360-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013618994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/14.7.1722", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016289313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1998.5423", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016481097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/70539", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017222001", 
          "https://doi.org/10.1038/70539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/70539", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017222001", 
          "https://doi.org/10.1038/70539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017350084", 
          "https://doi.org/10.1038/7771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7771", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017350084", 
          "https://doi.org/10.1038/7771"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-88178-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017975083", 
          "https://doi.org/10.1007/978-3-642-88178-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/978-3-642-88178-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017975083", 
          "https://doi.org/10.1007/978-3-642-88178-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1998.5255", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020728592"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/15.22.9461", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021836850"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng0895-383", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022756729", 
          "https://doi.org/10.1038/ng0895-383"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/a:1009256613348", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023099053", 
          "https://doi.org/10.1023/a:1009256613348"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/1-59259-192-2:365", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023668922", 
          "https://doi.org/10.1385/1-59259-192-2:365"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(95)90442-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024160504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(95)90460-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024818119"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.2000.6260", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025844430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/oxfordjournals.hmg.a018920", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027663004"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1997.0951", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028174721"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bies.950170407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028552972"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmg.37.10.752", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028788216"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/12.3.503", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029046032"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/14.12.3023", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030478520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/5.7.933", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032542838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1998.5526", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035353019"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.278.5338.675", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036670098"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0140-6736(96)90938-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037424118"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/geno.1993.1190", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038562661"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35057170", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039691728", 
          "https://doi.org/10.1038/35057170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35057170", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039691728", 
          "https://doi.org/10.1038/35057170"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/13.12.3332", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041968959"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/14.1.33", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042450576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35057062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042854081", 
          "https://doi.org/10.1038/35057062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35057062", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042854081", 
          "https://doi.org/10.1038/35057062"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/10279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043333106", 
          "https://doi.org/10.1038/10279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/10279", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043333106", 
          "https://doi.org/10.1038/10279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-9525(98)01555-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044342085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humrep/12.8.1635", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049941060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0092-8674(93)90616-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050270372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/9.17.2563", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051205660"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.94.8.3848", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053414239"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/1.1.29", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059643795"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/hmg/3.11.1965", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059644757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1359640", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062477300"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.286.5441.964", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062567135"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074529045", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmg.36.9.670", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1074529045"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.7.10.996", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083159140"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1101/gr.8.5.562", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083259069"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2001-11", 
    "datePublishedReg": "2001-11-01", 
    "description": "Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the most common known cause of spermatogenic failure. We determined the complete nucleotide sequence of AZFc by identifying and distinguishing between near-identical amplicons (massive repeat units) using an iterative mapping-sequencing process. A complex of three palindromes, the largest spanning 3 Mb with 99.97% identity between its arms, encompasses the AZFc region. The palindromes are constructed from six distinct families of amplicons, with unit lengths of 115-678 kb, and may have resulted from tandem duplication and inversion during primate evolution. The palindromic complex contains 11 families of transcription units, all expressed in testis. Deletions of AZFc that cause infertility are remarkably uniform, spanning a 3.5-Mb segment and bounded by 229-kb direct repeats that probably served as substrates for homologous recombination.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ng757", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": false, 
    "isPartOf": [
      {
        "id": "sg:journal.1103138", 
        "issn": [
          "1061-4036", 
          "1546-1718"
        ], 
        "name": "Nature Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "3", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "29"
      }
    ], 
    "name": "The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men", 
    "pagination": "279-286", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "c33f22fd38025f5d030b9e9cd7b00e7b3afa8da955e8622b46c71b23d80836f6"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "11687796"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9216904"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ng757"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1040986528"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ng757", 
      "https://app.dimensions.ai/details/publication/pub.1040986528"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T12:11", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000361_0000000361/records_53981_00000001.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ng/journal/v29/n3/full/ng757.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng757'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng757'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng757'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng757'


 

This table displays all metadata directly associated to this object as RDF triples.

381 TRIPLES      21 PREDICATES      102 URIs      46 LITERALS      34 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ng757 schema:about N1a92ddedc05b413cafc7e3a31780afc1
2 N3009b32c5e284f5799d197d8359a081e
3 N307927c001384bbaba3881e3f1ad7fde
4 N3657c62da4384a1d862589b9d30e781b
5 N3d8ec220e21f4ecba94af83226215a47
6 N57abda9d2cab422a9ce25b859a7fc7d9
7 N6251df2a2eac450f90127740e35c00bf
8 N6e1d040296ac4f728d9c0a594186efde
9 N785acf30255d4ece853c229789cd83a5
10 N8010a4d45de043f791ad45fe2fc03f99
11 N8e218bbf3fc644a597acccf7760d4578
12 N92f9eca5655a482dbaad85fe7b65a0af
13 Na6aeacf3d9f8488f85f5415bf6367a08
14 Na810a50704be48e89916a2241edff2dc
15 Ncc819b89d926446fb34c68e486d50395
16 Ncf2e028771004a6e972a9201f43894db
17 Nd55568be235a4cba9df02a489c1e0c99
18 Nd6b489c93a564b51b767dbc839915fc5
19 Nd813548b9a4e4c5590d8508f78b540d2
20 Nda31c15a050b4c35bcd6846f26aceb69
21 Ne2fef42d64944aa78cce3a954eda5106
22 Ne6db5e87542e4da283db458b4f330790
23 Nf1d9f0474cc542548d83752d1bcfd9a9
24 Nfb886810872945389d1abd0685f6b1f9
25 Nfccfc10dffde4fa98c05b542e79fd728
26 anzsrc-for:06
27 anzsrc-for:0604
28 schema:author N395800da1f354b209d0de5f9bcbc04bf
29 schema:citation sg:pub.10.1007/978-3-642-88178-7
30 sg:pub.10.1023/a:1009256613348
31 sg:pub.10.1038/10279
32 sg:pub.10.1038/35057062
33 sg:pub.10.1038/35057170
34 sg:pub.10.1038/70539
35 sg:pub.10.1038/7771
36 sg:pub.10.1038/ng0895-383
37 sg:pub.10.1038/ng1196-292
38 sg:pub.10.1385/1-59259-192-2:365
39 https://app.dimensions.ai/details/publication/pub.1074529045
40 https://doi.org/10.1002/bies.950170407
41 https://doi.org/10.1006/geno.1993.1190
42 https://doi.org/10.1006/geno.1998.5255
43 https://doi.org/10.1006/geno.1998.5423
44 https://doi.org/10.1006/geno.1998.5526
45 https://doi.org/10.1006/geno.2000.6260
46 https://doi.org/10.1006/jmbi.1997.0951
47 https://doi.org/10.1016/0092-8674(93)90616-x
48 https://doi.org/10.1016/0092-8674(95)90442-5
49 https://doi.org/10.1016/0092-8674(95)90460-3
50 https://doi.org/10.1016/s0015-0282(97)80083-0
51 https://doi.org/10.1016/s0022-2836(05)80360-2
52 https://doi.org/10.1016/s0140-6736(96)90938-1
53 https://doi.org/10.1016/s0168-9525(98)01555-8
54 https://doi.org/10.1073/pnas.94.8.3848
55 https://doi.org/10.1093/hmg/1.1.29
56 https://doi.org/10.1093/hmg/3.11.1965
57 https://doi.org/10.1093/hmg/5.7.933
58 https://doi.org/10.1093/hmg/8.7.1177
59 https://doi.org/10.1093/hmg/9.17.2563
60 https://doi.org/10.1093/humrep/12.3.503
61 https://doi.org/10.1093/humrep/12.8.1635
62 https://doi.org/10.1093/humrep/13.12.3332
63 https://doi.org/10.1093/humrep/14.1.33
64 https://doi.org/10.1093/humrep/14.12.3023
65 https://doi.org/10.1093/humrep/14.7.1722
66 https://doi.org/10.1093/nar/15.22.9461
67 https://doi.org/10.1093/oxfordjournals.hmg.a018920
68 https://doi.org/10.1101/gr.7.10.996
69 https://doi.org/10.1101/gr.8.5.562
70 https://doi.org/10.1126/science.1359640
71 https://doi.org/10.1126/science.278.5338.675
72 https://doi.org/10.1126/science.286.5441.964
73 https://doi.org/10.1136/bmj.291.6510.1693
74 https://doi.org/10.1136/jmg.36.9.670
75 https://doi.org/10.1136/jmg.37.10.752
76 https://doi.org/10.1159/000185175
77 schema:datePublished 2001-11
78 schema:datePublishedReg 2001-11-01
79 schema:description Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the most common known cause of spermatogenic failure. We determined the complete nucleotide sequence of AZFc by identifying and distinguishing between near-identical amplicons (massive repeat units) using an iterative mapping-sequencing process. A complex of three palindromes, the largest spanning 3 Mb with 99.97% identity between its arms, encompasses the AZFc region. The palindromes are constructed from six distinct families of amplicons, with unit lengths of 115-678 kb, and may have resulted from tandem duplication and inversion during primate evolution. The palindromic complex contains 11 families of transcription units, all expressed in testis. Deletions of AZFc that cause infertility are remarkably uniform, spanning a 3.5-Mb segment and bounded by 229-kb direct repeats that probably served as substrates for homologous recombination.
80 schema:genre research_article
81 schema:inLanguage en
82 schema:isAccessibleForFree false
83 schema:isPartOf N45ad20d18f244234985496f6980be522
84 N8b6f0715dd364446a1411bf5c71f3e26
85 sg:journal.1103138
86 schema:name The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men
87 schema:pagination 279-286
88 schema:productId N412bbc37cdd7465c99c4b2b64f171ed4
89 N56f117ebb9fc46d58aff90160d11db97
90 N74a0b4092dad44b8b3277481fcce420a
91 N7b986b2133f64873bec1ebb1e23af016
92 Ncf66d08199284b0691965c732d011c57
93 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040986528
94 https://doi.org/10.1038/ng757
95 schema:sdDatePublished 2019-04-11T12:11
96 schema:sdLicense https://scigraph.springernature.com/explorer/license/
97 schema:sdPublisher Nb7ad7cbfc98149edaea397c0ecdbac8c
98 schema:url http://www.nature.com/ng/journal/v29/n3/full/ng757.html
99 sgo:license sg:explorer/license/
100 sgo:sdDataset articles
101 rdf:type schema:ScholarlyArticle
102 N02c92f013a66499ba089dd2796179328 rdf:first sg:person.01111611776.37
103 rdf:rest N78870ba2e788499f964872a014560302
104 N0875f6a8fc9c4aa5b49f9f904167fdee rdf:first N9565e13900314fe195221bf686cf6303
105 rdf:rest N4f08b29748494d94971803e43a02f15f
106 N0bdead5149944262b0cf44e9bdba1fbb rdf:first sg:person.0772724136.39
107 rdf:rest N97f7534d6edb4dfca0be93ef9930f23a
108 N123de808f93048bc8a8ea63076e54b5f rdf:first sg:person.01266753034.97
109 rdf:rest N4f435f09ea0f4eb28c29e211c1232489
110 N1a92ddedc05b413cafc7e3a31780afc1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
111 schema:name RNA-Binding Proteins
112 rdf:type schema:DefinedTerm
113 N3009b32c5e284f5799d197d8359a081e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
114 schema:name Sequence Analysis, DNA
115 rdf:type schema:DefinedTerm
116 N307927c001384bbaba3881e3f1ad7fde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Deleted in Azoospermia 1 Protein
118 rdf:type schema:DefinedTerm
119 N3657c62da4384a1d862589b9d30e781b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name Male
121 rdf:type schema:DefinedTerm
122 N395800da1f354b209d0de5f9bcbc04bf rdf:first sg:person.0702641052.21
123 rdf:rest N123de808f93048bc8a8ea63076e54b5f
124 N3d8ec220e21f4ecba94af83226215a47 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
125 schema:name Organ Specificity
126 rdf:type schema:DefinedTerm
127 N3eeab05d5ed9416c9c578396174b879e rdf:first sg:person.01224407762.64
128 rdf:rest rdf:nil
129 N412bbc37cdd7465c99c4b2b64f171ed4 schema:name doi
130 schema:value 10.1038/ng757
131 rdf:type schema:PropertyValue
132 N45ad20d18f244234985496f6980be522 schema:issueNumber 3
133 rdf:type schema:PublicationIssue
134 N4f08b29748494d94971803e43a02f15f rdf:first sg:person.01017067452.18
135 rdf:rest N0bdead5149944262b0cf44e9bdba1fbb
136 N4f435f09ea0f4eb28c29e211c1232489 rdf:first sg:person.012271742572.52
137 rdf:rest N0875f6a8fc9c4aa5b49f9f904167fdee
138 N56f117ebb9fc46d58aff90160d11db97 schema:name nlm_unique_id
139 schema:value 9216904
140 rdf:type schema:PropertyValue
141 N57abda9d2cab422a9ce25b859a7fc7d9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
142 schema:name Gene Duplication
143 rdf:type schema:DefinedTerm
144 N6251df2a2eac450f90127740e35c00bf schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
145 schema:name Base Sequence
146 rdf:type schema:DefinedTerm
147 N6e1d040296ac4f728d9c0a594186efde schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
148 schema:name Tandem Repeat Sequences
149 rdf:type schema:DefinedTerm
150 N74a0b4092dad44b8b3277481fcce420a schema:name pubmed_id
151 schema:value 11687796
152 rdf:type schema:PropertyValue
153 N785acf30255d4ece853c229789cd83a5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
154 schema:name Chromosome Inversion
155 rdf:type schema:DefinedTerm
156 N78870ba2e788499f964872a014560302 rdf:first sg:person.013130175037.28
157 rdf:rest N3eeab05d5ed9416c9c578396174b879e
158 N7b986b2133f64873bec1ebb1e23af016 schema:name readcube_id
159 schema:value c33f22fd38025f5d030b9e9cd7b00e7b3afa8da955e8622b46c71b23d80836f6
160 rdf:type schema:PropertyValue
161 N8010a4d45de043f791ad45fe2fc03f99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Sequence Deletion
163 rdf:type schema:DefinedTerm
164 N8b6f0715dd364446a1411bf5c71f3e26 schema:volumeNumber 29
165 rdf:type schema:PublicationVolume
166 N8e218bbf3fc644a597acccf7760d4578 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
167 schema:name Chromosomes, Human, Pair 3
168 rdf:type schema:DefinedTerm
169 N92f9eca5655a482dbaad85fe7b65a0af schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
170 schema:name Humans
171 rdf:type schema:DefinedTerm
172 N9565e13900314fe195221bf686cf6303 schema:familyName Minx
173 schema:givenName P J
174 rdf:type schema:Person
175 N97f7534d6edb4dfca0be93ef9930f23a rdf:first sg:person.013076541047.38
176 rdf:rest Nb96d06f3fdcf4c70834b3778e9a8c655
177 Na6aeacf3d9f8488f85f5415bf6367a08 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Transcription, Genetic
179 rdf:type schema:DefinedTerm
180 Na810a50704be48e89916a2241edff2dc schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Molecular Sequence Data
182 rdf:type schema:DefinedTerm
183 Nb7ad7cbfc98149edaea397c0ecdbac8c schema:name Springer Nature - SN SciGraph project
184 rdf:type schema:Organization
185 Nb96d06f3fdcf4c70834b3778e9a8c655 rdf:first sg:person.01270344172.00
186 rdf:rest N02c92f013a66499ba089dd2796179328
187 Ncc819b89d926446fb34c68e486d50395 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
188 schema:name Evolution, Molecular
189 rdf:type schema:DefinedTerm
190 Ncf2e028771004a6e972a9201f43894db schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
191 schema:name Physical Chromosome Mapping
192 rdf:type schema:DefinedTerm
193 Ncf66d08199284b0691965c732d011c57 schema:name dimensions_id
194 schema:value pub.1040986528
195 rdf:type schema:PropertyValue
196 Nd55568be235a4cba9df02a489c1e0c99 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Testis
198 rdf:type schema:DefinedTerm
199 Nd6b489c93a564b51b767dbc839915fc5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
200 schema:name Y Chromosome
201 rdf:type schema:DefinedTerm
202 Nd813548b9a4e4c5590d8508f78b540d2 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
203 schema:name Oligospermia
204 rdf:type schema:DefinedTerm
205 Nda31c15a050b4c35bcd6846f26aceb69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
206 schema:name Chromosome Deletion
207 rdf:type schema:DefinedTerm
208 Ne2fef42d64944aa78cce3a954eda5106 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
209 schema:name Sequence Homology, Nucleic Acid
210 rdf:type schema:DefinedTerm
211 Ne6db5e87542e4da283db458b4f330790 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
212 schema:name Infertility, Male
213 rdf:type schema:DefinedTerm
214 Nf1d9f0474cc542548d83752d1bcfd9a9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
215 schema:name Spermatozoa
216 rdf:type schema:DefinedTerm
217 Nfb886810872945389d1abd0685f6b1f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
218 schema:name Recombination, Genetic
219 rdf:type schema:DefinedTerm
220 Nfccfc10dffde4fa98c05b542e79fd728 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
221 schema:name Models, Genetic
222 rdf:type schema:DefinedTerm
223 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
224 schema:name Biological Sciences
225 rdf:type schema:DefinedTerm
226 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
227 schema:name Genetics
228 rdf:type schema:DefinedTerm
229 sg:journal.1103138 schema:issn 1061-4036
230 1546-1718
231 schema:name Nature Genetics
232 rdf:type schema:Periodical
233 sg:person.01017067452.18 schema:familyName Cordum
234 schema:givenName H S
235 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01017067452.18
236 rdf:type schema:Person
237 sg:person.01111611776.37 schema:familyName Oates
238 schema:givenName R
239 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01111611776.37
240 rdf:type schema:Person
241 sg:person.01224407762.64 schema:familyName Page
242 schema:givenName D C
243 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01224407762.64
244 rdf:type schema:Person
245 sg:person.012271742572.52 schema:familyName Brown
246 schema:givenName L G
247 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012271742572.52
248 rdf:type schema:Person
249 sg:person.01266753034.97 schema:familyName Skaletsky
250 schema:givenName H
251 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266753034.97
252 rdf:type schema:Person
253 sg:person.01270344172.00 schema:familyName Silber
254 schema:givenName S
255 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01270344172.00
256 rdf:type schema:Person
257 sg:person.013076541047.38 schema:familyName Wilson
258 schema:givenName R K
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013076541047.38
260 rdf:type schema:Person
261 sg:person.013130175037.28 schema:familyName Rozen
262 schema:givenName S
263 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013130175037.28
264 rdf:type schema:Person
265 sg:person.0702641052.21 schema:affiliation https://www.grid.ac/institutes/grid.413575.1
266 schema:familyName Kuroda-Kawaguchi
267 schema:givenName T
268 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0702641052.21
269 rdf:type schema:Person
270 sg:person.0772724136.39 schema:familyName Waterston
271 schema:givenName R H
272 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0772724136.39
273 rdf:type schema:Person
274 sg:pub.10.1007/978-3-642-88178-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017975083
275 https://doi.org/10.1007/978-3-642-88178-7
276 rdf:type schema:CreativeWork
277 sg:pub.10.1023/a:1009256613348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023099053
278 https://doi.org/10.1023/a:1009256613348
279 rdf:type schema:CreativeWork
280 sg:pub.10.1038/10279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043333106
281 https://doi.org/10.1038/10279
282 rdf:type schema:CreativeWork
283 sg:pub.10.1038/35057062 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042854081
284 https://doi.org/10.1038/35057062
285 rdf:type schema:CreativeWork
286 sg:pub.10.1038/35057170 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039691728
287 https://doi.org/10.1038/35057170
288 rdf:type schema:CreativeWork
289 sg:pub.10.1038/70539 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017222001
290 https://doi.org/10.1038/70539
291 rdf:type schema:CreativeWork
292 sg:pub.10.1038/7771 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017350084
293 https://doi.org/10.1038/7771
294 rdf:type schema:CreativeWork
295 sg:pub.10.1038/ng0895-383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022756729
296 https://doi.org/10.1038/ng0895-383
297 rdf:type schema:CreativeWork
298 sg:pub.10.1038/ng1196-292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012147825
299 https://doi.org/10.1038/ng1196-292
300 rdf:type schema:CreativeWork
301 sg:pub.10.1385/1-59259-192-2:365 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023668922
302 https://doi.org/10.1385/1-59259-192-2:365
303 rdf:type schema:CreativeWork
304 https://app.dimensions.ai/details/publication/pub.1074529045 schema:CreativeWork
305 https://doi.org/10.1002/bies.950170407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028552972
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1006/geno.1993.1190 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038562661
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1006/geno.1998.5255 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020728592
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1006/geno.1998.5423 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016481097
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1006/geno.1998.5526 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035353019
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1006/geno.2000.6260 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025844430
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1006/jmbi.1997.0951 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028174721
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/0092-8674(93)90616-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050270372
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/0092-8674(95)90442-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024160504
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/0092-8674(95)90460-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024818119
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1016/s0015-0282(97)80083-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004328031
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1016/s0022-2836(05)80360-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013618994
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1016/s0140-6736(96)90938-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037424118
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1016/s0168-9525(98)01555-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044342085
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1073/pnas.94.8.3848 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053414239
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1093/hmg/1.1.29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059643795
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1093/hmg/3.11.1965 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059644757
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1093/hmg/5.7.933 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032542838
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1093/hmg/8.7.1177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000300808
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1093/hmg/9.17.2563 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051205660
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1093/humrep/12.3.503 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029046032
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1093/humrep/12.8.1635 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049941060
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1093/humrep/13.12.3332 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041968959
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1093/humrep/14.1.33 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042450576
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1093/humrep/14.12.3023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030478520
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1093/humrep/14.7.1722 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016289313
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1093/nar/15.22.9461 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021836850
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1093/oxfordjournals.hmg.a018920 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027663004
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1101/gr.7.10.996 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083159140
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1101/gr.8.5.562 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083259069
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1126/science.1359640 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062477300
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1126/science.278.5338.675 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036670098
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1126/science.286.5441.964 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062567135
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1136/bmj.291.6510.1693 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005990102
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1136/jmg.36.9.670 schema:sameAs https://app.dimensions.ai/details/publication/pub.1074529045
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1136/jmg.37.10.752 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028788216
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1159/000185175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009783130
378 rdf:type schema:CreativeWork
379 https://www.grid.ac/institutes/grid.413575.1 schema:alternateName Howard Hughes Medical Institute
380 schema:name Howard Hughes Medical Institute, 9 Cambridge Center, Cambridge, Massachusetts 02142, USA.
381 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...