Assembly of microarrays for genome-wide measurement of DNA copy number View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2001-11

AUTHORS

Antoine M. Snijders, Norma Nowak, Richard Segraves, Stephanie Blackwood, Nils Brown, Jeffrey Conroy, Greg Hamilton, Anna Katherine Hindle, Bing Huey, Karen Kimura, Sindy Law, Ken Myambo, Joel Palmer, Bauke Ylstra, Jingzhu Pearl Yue, Joe W. Gray, Ajay N. Jain, Daniel Pinkel, Donna G. Albertson

ABSTRACT

We have assembled arrays of approximately 2,400 BAC clones for measurement of DNA copy number across the human genome. The arrays provide precise measurement (s.d. of log2 ratios=0.05-0.10) in cell lines and clinical material, so that we can reliably detect and quantify high-level amplifications and single-copy alterations in diploid, polyploid and heterogeneous backgrounds. More... »

PAGES

263-264

Journal

TITLE

Nature Genetics

ISSUE

3

VOLUME

29

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng754

    DOI

    http://dx.doi.org/10.1038/ng754

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1010978328

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/11687795


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