Ontology type: schema:ScholarlyArticle
1993-09
AUTHORS ABSTRACTWe describe a method for stretching DNA, which, when combined with fluorescent hybridization procedures, forms a new mapping technology that produces a high resolution, vivid, multi–colour image and map. Restriction fragments and cosmid probes were successfully mapped by this procedure with validation by standard restriction mapping. A long range map of a >200 kilobase region containing five copies of the amplified dihydrofolate reductase gene was easily generated within two days. This DNA mapping procedure offers a significant and rapid alternative to a variety of standard mapping procedures. More... »
PAGES17-21
http://scigraph.springernature.com/pub.10.1038/ng0993-17
DOIhttp://dx.doi.org/10.1038/ng0993-17
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1011197729
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/8106079
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Genetics",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Animals",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chromosome Mapping",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chromosome Walking",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cosmids",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cricetinae",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA Probes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Genes",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "In Situ Hybridization, Fluorescence",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Interphase",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Polymorphism, Restriction Fragment Length",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Restriction Mapping",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Stress, Mechanical",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Tetrahydrofolate Dehydrogenase",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "The Cancer Therapy and Research Center, 8122 Datapoint Drive, 78229, San Antonio, Texas, USA",
"id": "http://www.grid.ac/institutes/grid.267309.9",
"name": [
"The Cancer Therapy and Research Center, 8122 Datapoint Drive, 78229, San Antonio, Texas, USA"
],
"type": "Organization"
},
"familyName": "Parra",
"givenName": "Irma",
"id": "sg:person.0636117075.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0636117075.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "The Cancer Therapy and Research Center, 8122 Datapoint Drive, 78229, San Antonio, Texas, USA",
"id": "http://www.grid.ac/institutes/grid.267309.9",
"name": [
"The Cancer Therapy and Research Center, 8122 Datapoint Drive, 78229, San Antonio, Texas, USA"
],
"type": "Organization"
},
"familyName": "Windle",
"givenName": "Bradford",
"id": "sg:person.011032075674.12",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011032075674.12"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/bf01671941",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1012019599",
"https://doi.org/10.1007/bf01671941"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng1192-171",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045306014",
"https://doi.org/10.1038/ng1192-171"
],
"type": "CreativeWork"
}
],
"datePublished": "1993-09",
"datePublishedReg": "1993-09-01",
"description": "We describe a method for stretching DNA, which, when combined with fluorescent hybridization procedures, forms a new mapping technology that produces a high resolution, vivid, multi\u2013colour image and map. Restriction fragments and cosmid probes were successfully mapped by this procedure with validation by standard restriction mapping. A long range map of a >200 kilobase region containing five copies of the amplified dihydrofolate reductase gene was easily generated within two days. This DNA mapping procedure offers a significant and rapid alternative to a variety of standard mapping procedures.",
"genre": "article",
"id": "sg:pub.10.1038/ng0993-17",
"inLanguage": "en",
"isAccessibleForFree": false,
"isPartOf": [
{
"id": "sg:journal.1103138",
"issn": [
"1061-4036",
"1546-1718"
],
"name": "Nature Genetics",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "1",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "5"
}
],
"keywords": [
"rapid alternative",
"high resolution",
"probe",
"DNA",
"fragments",
"procedure",
"method",
"variety",
"hybridization procedure",
"resolution",
"mapping procedure",
"alternative",
"technology",
"hybridization",
"restriction fragments",
"multi-color images",
"validation",
"mapping",
"region",
"mapping technology",
"images",
"reductase gene",
"fluorescent hybridization",
"maps",
"range maps",
"visual mapping",
"new mapping technologies",
"restriction mapping",
"days",
"kilobase region",
"copies",
"dihydrofolate reductase gene",
"genes",
"cosmid probes",
"long-range map",
"standard mapping procedures"
],
"name": "High resolution visual mapping of stretched DNA by fluorescent hybridization",
"pagination": "17-21",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1011197729"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/ng0993-17"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"8106079"
]
}
],
"sameAs": [
"https://doi.org/10.1038/ng0993-17",
"https://app.dimensions.ai/details/publication/pub.1011197729"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:19",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_260.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/ng0993-17"
}
]Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng0993-17'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng0993-17'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng0993-17'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng0993-17'
This table displays all metadata directly associated to this object as RDF triples.
169 TRIPLES
22 PREDICATES
79 URIs
69 LITERALS
21 BLANK NODES