Minisatellite diversity supports a recent African origin for modern humans View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1996-06

AUTHORS

J A Armour, T Anttinen, C A May, E E Vega, A Sajantila, J R Kidd, K K Kidd, J Bertranpetit, S Pääbo, A J Jeffreys

ABSTRACT

In a study of human diversity at a highly variable locus, we have mapped the internal structures of tandem-repetitive alleles from different populations at the minisatellite MS205 (D16S309). The results give an unusually detailed view of the different allelic structures represented on modern human chromosomes, and of the ancestral relationships between them. There was a clear difference in allelic diversity between African and non-African populations. A restricted set of allele families was found in non-African populations, and formed a subset of the much greater diversity seen on African chromosomes. The data strongly support a recent African origin for modern human diversity at this locus. More... »

PAGES

154

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng0696-154

DOI

http://dx.doi.org/10.1038/ng0696-154

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1041642949

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/8640220


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