Automated DNA sequencing and analysis of 106 kilobases from human chromosome 19q13.3 View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1992-04

AUTHORS

A. Martin-Gallardo, W. R. McCombie, J. D. Gocayne, M. G. FitzGerald, S. Wallace, B. M. B. Lee, J. Lamerdin, S. Trapp, J. M. Kelley, L-I. Liu, M. Dubnick, L. A. Johnston-Dow, A. R. Kerlavage, P. de Jong, A. Carrano, C. Fields, J. C. Venter

ABSTRACT

A total of 116,118 basepairs (bp) derived from three cosmids spanning the ERCC1 locus of human chromosome 19q13.3 have been sequenced with automated fluorescence-based sequencers and analysed by polymerase chain reaction amplification and computer methods. The assembled sequence forms two contigs totalling 105,831 bp, which contain a human fosB proto-oncogene, a gene encoding a protein phosphatase, two genes of unknown function and the previously-characterized ERCC1 DNA repair gene. This light band region has a high average density of 1.4 Alu repeats per kilobase. Human chromosome light bands could therefore contain up to 75,000 genes and 1.5 million Alu repeats. More... »

PAGES

34-39

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng0492-34

DOI

http://dx.doi.org/10.1038/ng0492-34

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1000554284

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/1301997


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Download the RDF metadata as:  json-ld nt turtle xml License info

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N-Triples is a line-based linked data format ideal for batch operations.

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Turtle is a human-readable linked data format.

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RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng0492-34'


 

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