Anthrax target in macrophages unveiled View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2006-02

AUTHORS

Thomas H Bugge, Stephen H Leppla

ABSTRACT

Anthrax lethal toxin lyses macrophages derived from certain inbred mice but not others, forming the basis of a bioassay widely used in the development of antibodies and drugs to treat anthrax. A new study identifies two genes essential for this lysis, revealing potential links between toxin-induced proteolysis and cellular killing.

PAGES

137

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng0206-137

DOI

http://dx.doi.org/10.1038/ng0206-137

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1014385567

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/16444249


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