Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-01

AUTHORS

Peter Broderick, Daniel Chubb, David C Johnson, Niels Weinhold, Asta Försti, Amy Lloyd, Bianca Olver, Yussanne P, Sara E Dobbins, Brian A Walker, Faith E Davies, Walter A Gregory, J Anthony Child, Fiona M Ross, Graham H Jackson, Kai Neben, Anna Jauch, Per Hoffmann, Thomas W Mühleisen, Markus M Nöthen, Susanne Moebus, Ian P Tomlinson, Hartmut Goldschmidt, Kari Hemminki, Gareth J Morgan, Richard S Houlston

ABSTRACT

To identify risk variants for multiple myeloma, we conducted a genome-wide association study of 1,675 individuals with multiple myeloma and 5,903 control subjects. We identified risk loci for multiple myeloma at 3p22.1 (rs1052501 in ULK4; odds ratio (OR) = 1.32; P = 7.47 × 10(-9)) and 7p15.3 (rs4487645, OR = 1.38; P = 3.33 × 10(-15)). In addition, we observed a promising association at 2p23.3 (rs6746082, OR = 1.29; P = 1.22 × 10(-7)). Our study identifies new genomic regions associated with multiple myeloma risk that may lead to new etiological insights. More... »

PAGES

58

References to SciGraph publications

  • 2004-12. 'Racial' differences in genetic effects for complex diseases in NATURE GENETICS
  • 2006-09. Deletion of chromosome 13 detected by conventional cytogenetics is a critical prognostic factor in myeloma in LEUKEMIA
  • 2005-11. Population structure, differential bias and genomic control in a large-scale, case-control association study in NATURE GENETICS
  • 2009-10. Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis in LEUKEMIA
  • 2010-02. Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence chronic lymphocytic leukemia risk in NATURE GENETICS
  • 2010-12. A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3) in NATURE GENETICS
  • 2006-08. Principal components analysis corrects for stratification in genome-wide association studies in NATURE GENETICS
  • 2003-02. Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma in LEUKEMIA
  • 2005-02. Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma in LEUKEMIA
  • 2009-12. International Myeloma Working Group molecular classification of multiple myeloma: spotlight review in LEUKEMIA
  • 2008-05. A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3 in NATURE GENETICS
  • 2010-07. Plasmablastic lymphoma with MYC translocation: evidence for a common pathway in the generation of plasmablastic features in MODERN PATHOLOGY
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.993

    DOI

    http://dx.doi.org/10.1038/ng.993

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034513761

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/22120009


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