Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2011-05-15

AUTHORS

Norihiro Kato, Fumihiko Takeuchi, Yasuharu Tabara, Tanika N Kelly, Min Jin Go, Xueling Sim, Wan Ting Tay, Chien-Hsiun Chen, Yi Zhang, Ken Yamamoto, Tomohiro Katsuya, Mitsuhiro Yokota, Young Jin Kim, Rick Twee Hee Ong, Toru Nabika, Dongfeng Gu, Li-ching Chang, Yoshihiro Kokubo, Wei Huang, Keizo Ohnaka, Yukio Yamori, Eitaro Nakashima, Cashell E Jaquish, Jong-Young Lee, Mark Seielstad, Masato Isono, James E Hixson, Yuan-Tsong Chen, Tetsuro Miki, Xueya Zhou, Takao Sugiyama, Jae-Pil Jeon, Jian Jun Liu, Ryoichi Takayanagi, Sung Soo Kim, Tin Aung, Yun Ju Sung, Xuegong Zhang, Tien Yin Wong, Bok-Ghee Han, Shotai Kobayashi, Toshio Ogihara, Dingliang Zhu, Naoharu Iwai, Jer-Yuarn Wu, Yik Ying Teo, E Shyong Tai, Yoon Shin Cho, Jiang He

ABSTRACT

Norihiro Kato and colleagues perform a meta-analysis of genome-wide association studies to identify common variants associated with blood pressure variation in east Asians. They identify five new genome-wide significant signals and replicate seven loci previously discovered in populations of European ancestry.

PAGES

531-538

References to SciGraph publications

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  • 2009-05-10. Genome-wide association study of blood pressure and hypertension in NATURE GENETICS
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  • 2009-05-10. Genome-wide association study identifies eight loci associated with blood pressure in NATURE GENETICS
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  • 2007-11-08. New insights into the importance of aminopeptidase A in hypertension in HEART FAILURE REVIEWS
  • 2010-04-23. Recapitulation of two genomewide association studies on blood pressure and essential hypertension in the Korean population in JOURNAL OF HUMAN GENETICS
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  • 2006-10-10. The genetic dissection of essential hypertension in NATURE REVIEWS GENETICS
  • Journal

    TITLE

    Nature Genetics

    ISSUE

    6

    VOLUME

    43

    Author Affiliations

  • Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan
  • Department of Basic Medical Research and Education, Ehime University Graduate School of Medicine, Toon, Japan
  • Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA
  • Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Korea
  • Centre for Molecular Epidemiology, National University of Singapore, Singapore
  • Singapore Eye Research Institute, Singapore National Eye Centre, Singapore
  • School of Chinese Medicine, China Medical University, Taichung, Taiwan
  • Shanghai Institute of Hypertension, Shanghai, China
  • Division of Genome Analysis, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan
  • Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan
  • Department of Genome Science, Aichi-Gakuin University, School of Dentistry, Nagoya, Japan
  • National University of Singapore Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore
  • Department of Functional Pathology, Shimane University School of Medicine, Izumo, Japan
  • Chinese National Center for Cardiovascular Diseases, Beijing, China
  • Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan
  • Department of Preventive Cardiology, National Cerebral and Cardiovascular Center, Suita, Japan
  • Department of Genetics, Chinese National Human Genomic Center, Shanghai, China
  • Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
  • Mukogawa Women's University Institute for World Health Development, Nishinomiya, Japan
  • Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, Japan
  • Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, USA
  • Institute of Human Genetics, University of California, San Francisco, California, USA
  • Department of Epidemiology, University of Texas School of Public Health, Houston, Texas, USA
  • Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Japan
  • Department of Automation, Key Laboratory of Bioinformatics, Tsinghua University, Beijing, China
  • Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan
  • Genome Institute of Singapore, Agency for Science, Technology and Research, Singapore
  • Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
  • Department of Ophthalmology, National University of Singapore, Singapore
  • Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA
  • Center for Eye Research Australia, University of Melbourne, Melbourne, Australia
  • Director, Shimane University Hospital, Izumo, Japan
  • Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan
  • Department of Genomic Medicine, National Cerebral and Cardiovascular Center, Suita, Japan
  • Department of Epidemiology and Public Health, National University of Singapore, Singapore
  • Department of Medicine, National University of Singapore, Singapore
  • Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.834

    DOI

    http://dx.doi.org/10.1038/ng.834

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1053345913

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/21572416


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