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Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index View Full Text

Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-10-10

AUTHORS

Elizabeth K Speliotes, Cristen J Willer, Sonja I Berndt, Keri L Monda, Gudmar Thorleifsson, Anne U Jackson, Hana Lango Allen, Cecilia M Lindgren, Jian'an Luan, Reedik Mägi, Joshua C Randall, Sailaja Vedantam, Thomas W Winkler, Lu Qi, Tsegaselassie Workalemahu, Iris M Heid, Valgerdur Steinthorsdottir, Heather M Stringham, Michael N Weedon, Eleanor Wheeler, Andrew R Wood, Teresa Ferreira, Robert J Weyant, Ayellet V Segrè, Karol Estrada, Liming Liang, James Nemesh, Ju-Hyun Park, Stefan Gustafsson, Tuomas O Kilpeläinen, Jian Yang, Nabila Bouatia-Naji, Tõnu Esko, Mary F Feitosa, Zoltán Kutalik, Massimo Mangino, Soumya Raychaudhuri, Andre Scherag, Albert Vernon Smith, Ryan Welch, Jing Hua Zhao, Katja K Aben, Devin M Absher, Najaf Amin, Anna L Dixon, Eva Fisher, Nicole L Glazer, Michael E Goddard, Nancy L Heard-Costa, Volker Hoesel, Jouke-Jan Hottenga, Åsa Johansson, Toby Johnson, Shamika Ketkar, Claudia Lamina, Shengxu Li, Miriam F Moffatt, Richard H Myers, Narisu Narisu, John R B Perry, Marjolein J Peters, Michael Preuss, Samuli Ripatti, Fernando Rivadeneira, Camilla Sandholt, Laura J Scott, Nicholas J Timpson, Jonathan P Tyrer, Sophie van Wingerden, Richard M Watanabe, Charles C White, Fredrik Wiklund, Christina Barlassina, Daniel I Chasman, Matthew N Cooper, John-Olov Jansson, Robert W Lawrence, Niina Pellikka, Inga Prokopenko, Jianxin Shi, Elisabeth Thiering, Helene Alavere, Maria T S Alibrandi, Peter Almgren, Alice M Arnold, Thor Aspelund, Larry D Atwood, Beverley Balkau, Anthony J Balmforth, Amanda J Bennett, Yoav Ben-Shlomo, Richard N Bergman, Sven Bergmann, Heike Biebermann, Alexandra I F Blakemore, Tanja Boes, Lori L Bonnycastle, Stefan R Bornstein, Morris J Brown, Thomas A Buchanan, Fabio Busonero, Harry Campbell, Francesco P Cappuccio, Christine Cavalcanti-Proença, Yii-Der Ida Chen, Chih-Mei Chen, Peter S Chines, Robert Clarke, Lachlan Coin, John Connell, Ian N M Day, Martin den Heijer, Jubao Duan, Shah Ebrahim, Paul Elliott, Roberto Elosua, Gudny Eiriksdottir, Michael R Erdos, Johan G Eriksson, Maurizio F Facheris, Stephan B Felix, Pamela Fischer-Posovszky, Aaron R Folsom, Nele Friedrich, Nelson B Freimer, Mao Fu, Stefan Gaget, Pablo V Gejman, Eco J C Geus, Christian Gieger, Anette P Gjesing, Anuj Goel, Philippe Goyette, Harald Grallert, Jürgen Gräßler, Danielle M Greenawalt, Christopher J Groves, Vilmundur Gudnason, Candace Guiducci, Anna-Liisa Hartikainen, Neelam Hassanali, Alistair S Hall, Aki S Havulinna, Caroline Hayward, Andrew C Heath, Christian Hengstenberg, Andrew A Hicks, Anke Hinney, Albert Hofman, Georg Homuth, Jennie Hui, Wilmar Igl, Carlos Iribarren, Bo Isomaa, Kevin B Jacobs, Ivonne Jarick, Elizabeth Jewell, Ulrich John, Torben Jørgensen, Pekka Jousilahti, Antti Jula, Marika Kaakinen, Eero Kajantie, Lee M Kaplan, Sekar Kathiresan, Johannes Kettunen, Leena Kinnunen, Joshua W Knowles, Ivana Kolcic, Inke R König, Seppo Koskinen, Peter Kovacs, Johanna Kuusisto, Peter Kraft, Kirsti Kvaløy, Jaana Laitinen, Olivier Lantieri, Chiara Lanzani, Lenore J Launer, Cecile Lecoeur, Terho Lehtimäki, Guillaume Lettre, Jianjun Liu, Marja-Liisa Lokki, Mattias Lorentzon, Robert N Luben, Barbara Ludwig, Paolo Manunta, Diana Marek, Michel Marre, Nicholas G Martin, Wendy L McArdle, Anne McCarthy, Barbara McKnight, Thomas Meitinger, Olle Melander, David Meyre, Kristian Midthjell, Grant W Montgomery, Mario A Morken, Andrew P Morris, Rosanda Mulic, Julius S Ngwa, Mari Nelis, Matt J Neville, Dale R Nyholt, Christopher J O'Donnell, Stephen O'Rahilly, Ken K Ong, Ben Oostra, Guillaume Paré, Alex N Parker, Markus Perola, Irene Pichler, Kirsi H Pietiläinen, Carl G P Platou, Ozren Polasek, Anneli Pouta, Suzanne Rafelt, Olli Raitakari, Nigel W Rayner, Martin Ridderstråle, Winfried Rief, Aimo Ruokonen, Neil R Robertson, Peter Rzehak, Veikko Salomaa, Alan R Sanders, Manjinder S Sandhu, Serena Sanna, Jouko Saramies, Markku J Savolainen, Susann Scherag, Sabine Schipf, Stefan Schreiber, Heribert Schunkert, Kaisa Silander, Juha Sinisalo, David S Siscovick, Jan H Smit, Nicole Soranzo, Ulla Sovio, Jonathan Stephens, Ida Surakka, Amy J Swift, Mari-Liis Tammesoo, Jean-Claude Tardif, Maris Teder-Laving, Tanya M Teslovich, John R Thompson, Brian Thomson, Anke Tönjes, Tiinamaija Tuomi, Joyce B J van Meurs, Gert-Jan van Ommen, Vincent Vatin, Jorma Viikari, Sophie Visvikis-Siest, Veronique Vitart, Carla I G Vogel, Benjamin F Voight, Lindsay L Waite, Henri Wallaschofski, G Bragi Walters, Elisabeth Widen, Susanna Wiegand, Sarah H Wild, Gonneke Willemsen, Daniel R Witte, Jacqueline C Witteman, Jianfeng Xu, Qunyuan Zhang, Lina Zgaga, Andreas Ziegler, Paavo Zitting, John P Beilby, I Sadaf Farooqi, Johannes Hebebrand, Heikki V Huikuri, Alan L James, Mika Kähönen, Douglas F Levinson, Fabio Macciardi, Markku S Nieminen, Claes Ohlsson, Lyle J Palmer, Paul M Ridker, Michael Stumvoll, Jacques S Beckmann, Heiner Boeing, Eric Boerwinkle, Dorret I Boomsma, Mark J Caulfield, Stephen J Chanock, Francis S Collins, L Adrienne Cupples, George Davey Smith, Jeanette Erdmann, Philippe Froguel, Henrik Grönberg, Ulf Gyllensten, Per Hall, Torben Hansen, Tamara B Harris, Andrew T Hattersley, Richard B Hayes, Joachim Heinrich, Frank B Hu, Kristian Hveem, Thomas Illig, Marjo-Riitta Jarvelin, Jaakko Kaprio, Fredrik Karpe, Kay-Tee Khaw, Lambertus A Kiemeney, Heiko Krude, Markku Laakso, Debbie A Lawlor, Andres Metspalu, Patricia B Munroe, Willem H Ouwehand, Oluf Pedersen, Brenda W Penninx, Annette Peters, Peter P Pramstaller, Thomas Quertermous, Thomas Reinehr, Aila Rissanen, Igor Rudan, Nilesh J Samani, Peter E H Schwarz, Alan R Shuldiner, Timothy D Spector, Jaakko Tuomilehto, Manuela Uda, André Uitterlinden, Timo T Valle, Martin Wabitsch, Gérard Waeber, Nicholas J Wareham, Hugh Watkins, James F Wilson, Alan F Wright, M Carola Zillikens, Nilanjan Chatterjee, Steven A McCarroll, Shaun Purcell, Eric E Schadt, Peter M Visscher, Themistocles L Assimes, Ingrid B Borecki, Panos Deloukas, Caroline S Fox, Leif C Groop, Talin Haritunians, David J Hunter, Robert C Kaplan, Karen L Mohlke, Jeffrey R O'Connell, Leena Peltonen, David Schlessinger, David P Strachan, Cornelia M van Duijn, H-Erich Wichmann, Timothy M Frayling, Unnur Thorsteinsdottir, Gonçalo R Abecasis, Inês Barroso, Michael Boehnke, Kari Stefansson, Kari E North, Mark I McCarthy, Joel N Hirschhorn, Erik Ingelsson, Ruth J F Loos

ABSTRACT

Ruth Loos and colleagues report results of a large genome-wide association study for body mass index. They identify 18 new loci associated with this trait, some of which map near key hypothalamic regulators of energy balance.

PAGES

937-948

References to SciGraph publications

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    • Journal

    TITLE

    Nature Genetics

    ISSUE

    11

    VOLUME

    42

    Subjects

  • FOR: Biological Sciences
  • FOR: Genetics
  • MESH: Body Height
  • MESH: Body Mass Index
  • MESH: Body Size
  • MESH: Body Weight
  • MESH: Chromosome Mapping
  • MESH: Genetic Predisposition To Disease
  • MESH: Genome-Wide Association Study
  • MESH: Humans
  • MESH: Obesity
  • MESH: Polymorphism, Single Nucleotide
  • MESH: Whites

    • Author Affiliations

  • Division of Gastroenterology, Massachusetts General Hospital, Boston, Massachusetts, USA
  • Department of Biostatistics, Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA
  • Division of Cancer Epidemiology and Genetics, Department of Health and Human Services, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
  • Department of Epidemiology, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
  • deCODE Genetics, Reykjavik, Iceland
  • Genetics of Complex Traits, Peninsula College of Medicine and Dentistry, University of Exeter, Exeter, UK
  • Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
  • Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK
  • Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
  • Divisions of Genetics and Endocrinology and Program in Genomics, Children's Hospital, Boston, Massachusetts, USA
  • Department of Epidemiology and Preventive Medicine, Regensburg University Medical Center, Regensburg, Germany
  • Department of Medicine, Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA
  • Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA
  • Institute of Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany
  • Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK
  • Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts, USA
  • Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands
  • Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA
  • Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
  • Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • Queensland Statistical Genetics Laboratory, Queensland Institute of Medical Research, Queensland, Australia
  • University Lille Nord de France, Lille, France
  • Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia
  • Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Swiss Institute of Bioinformatics, Lausanne, Switzerland
  • Department of Twin Research and Genetic Epidemiology, King's College London, London, UK
  • Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA
  • Institute for Medical Informatics, Biometry and Epidemiology, University of Duisburg-Essen, Essen, Germany
  • University of Iceland, Reykjavik, Iceland
  • Comprehensive Cancer Center East, Nijmegen, The Netherlands
  • Hudson Alpha Institute for Biotechnology, Huntsville, Alabama, USA
  • Department of Epidemiology, Erasmus Medical Center (MC), Rotterdam, The Netherlands
  • Department of Pharmacy and Pharmacology, University of Bath, Bath, UK
  • Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany
  • Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA
  • Department of Primary Industries, Melbourne, Victoria, Australia.
  • Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA
  • Technical University Munich, Chair of Biomathematics, Garching, Germany
  • Department of Biological Psychology, Vrije Universiteit (VU) University Amsterdam, Amsterdam, The Netherlands
  • Department of Cancer Research and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway
  • Clinical Pharmacology and Barts and The London Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK
  • Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
  • National Heart and Lung Institute, Imperial College London, London, UK
  • National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA
  • Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Universitätsklinikum Schleswig-Holstein, Campus Lübeck, Lübeck, Germany
  • Department of Chronic Disease Prevention, National Institute for Health and Welfare, Unit of Public Health Genomics, Helsinki, Finland
  • Hagedorn Research Institute, Gentofte, Denmark
  • Department of Social Medicine, MRC Centre for Causal Analyses in Translational Epidemiology, Oakfield House, Bristol, UK
  • Department of Oncology, University of Cambridge, Cambridge, UK
  • Department of Physiology and Biophysics, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
  • Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA
  • Department of Medicine, University of Milan, Surgery and Dentistry, Milano, Italy
  • Harvard Medical School, Boston, Massachusetts, USA
  • Centre for Genetic Epidemiology and Biostatistics, University of Western Australia, Crawley, Western Australia, Australia
  • Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • Estonian Genome Center, University of Tartu, Tartu, Estonia
  • Division of Nephrology and Dialysis, University Vita-Salute San Raffaele, Milan, Italy
  • Department of Clinical Sciences, Lund University Diabetes Centre, Lund University, Malmö, Sweden
  • Collaborative Health Studies Coordinating Center, Seattle, Washington, USA
  • University Paris Sud 11, Unité Mixte de Recherche en Santé (UMRS) 1018, Villejuif, France
  • Multidisciplinary Cardiovascular Research Centre (MCRC), Leeds Institute of Genetics, Health and Therapeutics (LIGHT), University of Leeds, Leeds, UK
  • Department of Social Medicine, University of Bristol, Bristol, UK
  • Institute of Experimental Paediatric Endocrinology, Charité Universitätsmedizin Berlin, Berlin, Germany
  • Department of Genomics of Common Disease, School of Public Health, Imperial College London, London, UK
  • Department of Medicine III, University of Dresden, Dresden, Germany
  • Clinical Pharmacology Unit, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK
  • Division of Endocrinology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
  • Istituto di Neurogenetica e Neurofarmacologia del Consiglio Nazionale delle Ricerche (CNR), Monserrato, Cagliari, Italy
  • Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, Scotland, UK
  • University of Warwick, Warwick Medical School, Coventry, UK
  • Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
  • Clinical Trial Service Unit, Oxford, UK
  • Department of Epidemiology and Biostatistics, School of Public Health, Faculty of Medicine, Imperial College London, London, UK
  • University of Dundee, Ninewells Hospital and Medical School, Dundee, UK
  • Department of Endocrinology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  • Northshore University Healthsystem, Evanston, Illinois, USA
  • South Asia Network for Chronic Disease, New Dehli, India
  • MRC-Health Protection Agency (HPA) Centre for Environment and Health, London, UK
  • Cardiovascular Epidemiology and Genetics, Institut Municipal D'investigacio Medica and Centro de Investigación Biomédica en Red CIBER Epidemiología y Salud Pública, Barcelona, Spain
  • Icelandic Heart Association, Kopavogur, Iceland
  • Vasa Central Hospital, Vasa, Finland
  • Department of Neurology, General Central Hospital, Bolzano, Italy
  • Department of Internal Medicine B, Ernst-Moritz-Arndt University, Greifswald, Germany
  • Department of Pediatrics and Adolescent Medicine, Pediatric Endocrinology, Diabetes and Obesity Unit, Ulm, Germany
  • Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA
  • Institut für Klinische Chemie und Laboratoriumsmedizin, Universität Greifswald, Greifswald, Germany
  • Center for Neurobehavioral Genetics, University of California, Los Angeles, California, USA
  • Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA
  • Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Headington, Oxford, UK
  • Montreal Heart Institute, Montreal, Quebec, Canada
  • Department of Medicine III, Pathobiochemistry, University of Dresden, Dresden, Germany
  • Merck Research Laboratories, Merck and Co., Inc., Boston, Massachusetts, USA
  • Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
  • Department of Clinical Sciences, Obstetrics and Gynecology, University of Oulu, Oulu, Finland
  • Department of Chronic Disease Prevention, National Institute for Health and Welfare, Chronic Disease Epidemiology and Prevention Unit, Helsinki, Finland
  • MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, Scotland, UK
  • Department of Psychiatry and Midwest Alcoholism Research Center, Washington University School of Medicine, St. Louis, Missouri, USA
  • Regensburg University Medical Center, Innere Medizin II, Regensburg, Germany
  • Institute of Genetic Medicine, European Academy Bozen-Bolzano (EURAC), Bolzano-Bozen, Italy, Affiliated Institute of the University of Lübeck, Lübeck, Germany
  • Department of Child and Adolescent Psychiatry, University of Duisburg-Essen, Essen, Germany
  • Interfaculty Institute for Genetics and Functional Genomics, Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany
  • Busselton Population Medical Research Foundation Inc., Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
  • Department of Genetics and Pathology, Rudbeck Laboratory, University of Uppsala, Uppsala, Sweden
  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California, USA
  • Department of Social Services and Health Care, Jakobstad, Finland
  • Core Genotyping Facility, SAIC-Frederick, Inc., National Cancer Institute (NCI)-Frederick, Frederick, Maryland, USA
  • Institute of Medical Biometry and Epidemiology, University of Marburg, Marburg, Germany
  • Institut für Epidemiologie und Sozialmedizin, Universität Greifswald, Greifswald, Germany
  • Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
  • Department of Chronic Disease Prevention, National Institute for Health and Welfare, Population Studies Unit, Turku, Finland
  • Biocenter Oulu, University of Oulu, Oulu, Finland
  • Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Hospital District of Helsinki and Uusimaa (HUS), Helsinki, Finland
  • Massachusetts General Hospital (MGH) Weight Center, Massachusetts General Hospital, Boston, Massachusetts, USA
  • Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA
  • National Institute for Health and Welfare, Diabetes Prevention Unit, Helsinki, Finland
  • Department of Medicine, Stanford University School of Medicine, Stanford, California, USA
  • Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia
  • Interdisciplinary Centre for Clinical Research, University of Leipzig, Leipzig, Germany
  • Department of Medicine, University of Kuopio and Kuopio University Hospital, Kuopio, Finland
  • Department of Public Health and General Practice, Nord-Trøndelag Health Study (HUNT) Research Centre, Norwegian University of Science and Technology, Levanger, Norway
  • Finnish Institute of Occupational Health, Oulu, Finland
  • Institut inter-regional pour la santé (IRSA), La Riche, France
  • Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA
  • Department of Clinical Chemistry, University of Tampere and Tampere University Hospital, Tampere, Finland
  • Department of Medicine, Université de Montréal, Montreal, Quebec, Canada
  • Human Genetics, Genome Institute of Singapore, Singapore, Singapore
  • Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland
  • Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
  • Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK
  • Cardiovascular Genetics Research Unit, Université Henri Poincaré-Nancy 1, Nancy, France
  • Genetic Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia
  • Department of Social Medicine, Avon Longitudinal Study of Parents and Children (ALSPAC) Laboratory, University of Bristol, Bristol, UK
  • Division of Health, Research Board, An Bord Taighde Sláinte, Dublin, Ireland
  • Department of Biostatistics, University of Washington, Seattle, Washington, USA
  • Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany
  • Department of Clinical Sciences, Lund University, Malmö, Sweden
  • Molecular Epidemiology Laboratory, Queensland Institute of Medical Research, Queensland, Australia
  • Croatian Centre for Global Health, School of Medicine, University of Split, Split, Croatia
  • Neurogenetics Laboratory, Queensland Institute of Medical Research, Queensland, Australia
  • National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, Massachusetts, USA
  • University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK
  • Department of Clinical Genetics, Erasmus MC, Rotterdam, The Netherlands
  • Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
  • Amgen, Cambridge, Massachusetts, USA
  • Department of Psychiatry, Obesity Research Unit, Helsinki University Central Hospital, Helsinki, Finland
  • Department of Medicine, Levanger Hospital, The Nord-Trøndelag Health Trust, Levanger, Norway
  • Gen-Info Ltd, Zagreb, Croatia
  • National Institute for Health and Welfare, Oulu, Finland
  • Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
  • The Department of Clinical Physiology, Turku University Hospital, Turku, Finland
  • Clinical Psychology and Psychotherapy, University of Marburg, Marburg, Germany
  • Department of Clinical Sciences and Clinical Chemistry, University of Oulu, Oulu, Finland
  • Ludwig-Maximilians-Universität, Institute of Medical Informatics, Biometry and Epidemiology, Chair of Epidemiology, Munich, Germany
  • South Karelia Central Hospital, Lappeenranta, Finland
  • Department of Clinical Sciences and Internal Medicine, University of Oulu, Oulu, Finland
  • Institut für Community Medicine, Greifswald, Germany
  • Institute for Clinical Molecular Biology and Department of Internal Medicine I, Christian-Albrechts-University, University Hospital Schleswig-Holstein, Kiel, Germany
  • Universität zu Lübeck, Medizinische Klinik II, Lübeck, Germany
  • Division of Cardiology, Cardiovascular Laboratory, Helsinki University Central Hospital, Helsinki, Finland
  • Departments of Medicine and Epidemiology, University of Washington, Seattle, Washington, USA
  • Department of Psychiatry, Instituut voor Extramuraal Geneeskundig Onderzoek (EMGO) Institute, VU University Medical Center, Amsterdam, The Netherlands
  • National Health Service (NHS) Blood and Transplant, Cambridge Centre, Cambridge, UK
  • Department of Health Sciences, University of Leicester, University Road, Leicester, UK
  • Coordination Centre for Clinical Trials, University of Leipzig, Leipzig, Germany
  • Research Program of Molecular Medicine, University of Helsinki, Helsinki, Finland
  • Center of Medical Systems Biology, Leiden University Medical Center, Leiden, The Netherlands
  • Department of Medicine, University of Turku and Turku University Hospital, Turku, Finland
  • INSERM Cardiovascular Genetics team, Centre Investigation Clinique (CIC) 9501, Nancy, France
  • Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
  • Steno Diabetes Center, Gentofte, Denmark
  • Center for Human Genomics, Wake Forest University, Winston-Salem, North Carolina, USA
  • Department of Physiatrics, Lapland Central Hospital, Rovaniemi, Finland
  • School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Western Australia, Australia
  • Department of Internal Medicine, University of Oulu, Oulu, Finland
  • School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia
  • Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland
  • Stanford University School of Medicine, Stanford, California, USA
  • Department of Psychiatry and Human Behavior, University of California, Irvine (UCI), Irvine, California, USA
  • Leipziger Interdisziplinärer Forschungs-komplex zu molekularen Ursachen umwelt- und lebensstilassoziierter Erkrankungen (LIFE) Study Centre, University of Leipzig, Leipzig, Germany
  • Service of Medical Genetics, Centre Hospitalier Universitaire Vaudois (CHUV) University Hospital, Lausanne, Switzerland
  • Human Genetics Center and Institute of Molecular Medicine, University of Texas Health Science Center, Houston, Texas, USA
  • Faculty of Health Science, University of Southern Denmark, Odense, Denmark
  • New York University Medical Center, New York, New York, USA
  • Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
  • Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare, Unit for Child and Adolescent Mental Health, Helsinki, Finland
  • NIHR Oxford Biomedical Research Centre, Churchill Hospital, Oxford, UK
  • Department of Urology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  • Faculty of Health Science, University of Aarhus, Aarhus, Denmark
  • Department of Psychiatry, University Medical Centre Groningen, Groningen, The Netherlands
  • Department of Neurology, University of Lübeck, Lübeck, Germany
  • Institute for Paediatric Nutrition Medicine, Vestische Hospital for Children and Adolescents, University of Witten-Herdecke, Datteln, Germany
  • Leicester NIHR Biomedical Research Unit in Cardiovascular Disease, Glenfield Hospital, Leicester, UK
  • Department of Medicine III, Prevention and Care of Diabetes, University of Dresden, Dresden, Germany
  • Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, Maryland, USA
  • South Ostrobothnia Central Hospital, Seinajoki, Finland
  • Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois (CHUV) University Hospital, Lausanne, Switzerland
  • Department of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA
  • Sage Bionetworks, Seattle, Washington, USA
  • Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA
  • Division of Intramural Research, National Heart, Lung, and Blood Institute, Framingham Heart Study, Framingham, Massachusetts, USA
  • Department of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, New York, USA
  • Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA
  • Department of Medical Genetics, University of Helsinki, Helsinki, Finland
  • Laboratory of Genetics, National Institute on Aging, Baltimore, Maryland, USA
  • Division of Community Health Sciences, St. George's, University of London, London, UK
  • Klinikum Grosshadern, Munich, Germany
  • Faculty of Medicine, University of Iceland, Reykjavík, Iceland
  • University of Cambridge Metabolic Research Labs, Institute of Metabolic Science Addenbrooke's Hospital, Cambridge, UK
  • Carolina Center for Genome Sciences, School of Public Health, University of North Carolina Chapel Hill, Chapel Hill, North Carolina, USA
  • Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA

    • From Grant

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    http://dx.doi.org/10.1038/ng.686

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    https://www.ncbi.nlm.nih.gov/pubmed/20935630

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