Genome-wide association identifies multiple ulcerative colitis susceptibility loci View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-03-14

AUTHORS

Dermot P B McGovern, Agnès Gardet, Leif Törkvist, Philippe Goyette, Jonah Essers, Kent D Taylor, Benjamin M Neale, Rick T H Ong, Caroline Lagacé, Chun Li, Todd Green, Christine R Stevens, Claudine Beauchamp, Phillip R Fleshner, Marie Carlson, Mauro D'Amato, Jonas Halfvarson, Martin L Hibberd, Mikael Lördal, Leonid Padyukov, Angelo Andriulli, Elisabetta Colombo, Anna Latiano, Orazio Palmieri, Edmond-Jean Bernard, Colette Deslandres, Daan W Hommes, Dirk J de Jong, Pieter C Stokkers, Rinse K Weersma, Yashoda Sharma, Mark S Silverberg, Judy H Cho, Jing Wu, Kathryn Roeder, Steven R Brant, L Phillip Schumm, Richard H Duerr, Marla C Dubinsky, Nicole L Glazer, Talin Haritunians, Andy Ippoliti, Gil Y Melmed, David S Siscovick, Eric A Vasiliauskas, Stephan R Targan, Vito Annese, Cisca Wijmenga, Sven Pettersson, Jerome I Rotter, Ramnik J Xavier, Mark J Daly, John D Rioux, Mark Seielstad

ABSTRACT

Mark Seielstad and colleagues report results of a large genome-wide association and replication study of ulcerative colitis. The work identifies several new risk loci for this disease and provides further insight into the shared pathogenesis of ulcerative colitis and Crohn's disease.

PAGES

332-337

References to SciGraph publications

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  • Journal

    TITLE

    Nature Genetics

    ISSUE

    4

    VOLUME

    42

    Author Affiliations

  • Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
  • Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
  • Department for Clinical Science Intervention and Technology, Karolinska Institutet and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden
  • Université de Montréal and the Montreal Heart Institute, Research Center, Montréal, Québec, Canada
  • Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
  • Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
  • Human Genetics, Genome Institute of Singapore, Singapore
  • The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
  • Department of Medical Sciences, Gastroenterology Research Group, Uppsala University Hospital, Uppsala, Sweden
  • Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden
  • Division of Gastroenterology, Department of Internal Medicine, Örebro University Hospital, Örebro, Sweden
  • Infectious Diseases, Genome Institute of Singapore, Singapore
  • Department of Medicine, and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden
  • Department of Medicine, Rheumatology Unit, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden
  • Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy
  • Université de Montréal and Centre Hospitalier Universitaire de l'Université de Montréal, Montréal, Québec, Canada
  • Department of Gastroenterology, Hôpital Sainte-Justine, Montréal, Québec, Canada
  • Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands
  • Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
  • Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands
  • Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
  • Department of Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut, USA
  • Mount Sinai Hospital Inflammatory Bowel Disease Group, University of Toronto, Toronto, Ontario, Canada
  • Department of Genetics, Yale University, New Haven, Connecticut, USA
  • Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA
  • Department of Medicine, Department of Epidemiology, Johns Hopkins University School of Medicine, and Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA
  • Department of Health Studies, University of Chicago, Chicago, Illinois, USA
  • Division of Gastroenterology, Department of Medicine, and Department of Human Genetics, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
  • Departments of Epidemiology and General Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA
  • Department of Genetics, University Medical Center Groningen and Groningen University, Groningen, The Netherlands
  • Laboratory of Inflammation Biology, Singapore General Hospital, Singapore
  • Institute for Human Genetics, University of California San Fransisco, San Francisco, California, USA
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.549

    DOI

    http://dx.doi.org/10.1038/ng.549

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1031272000

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20228799


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