Genome-wide association identifies multiple ulcerative colitis susceptibility loci View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2010-04

AUTHORS

Dermot P B McGovern, Agnès Gardet, Leif Törkvist, Philippe Goyette, Jonah Essers, Kent D Taylor, Benjamin M Neale, Rick T H Ong, Caroline Lagacé, Chun Li, Todd Green, Christine R Stevens, Claudine Beauchamp, Phillip R Fleshner, Marie Carlson, Mauro D'Amato, Jonas Halfvarson, Martin L Hibberd, Mikael Lördal, Leonid Padyukov, Angelo Andriulli, Elisabetta Colombo, Anna Latiano, Orazio Palmieri, Edmond-Jean Bernard, Colette Deslandres, Daan W Hommes, Dirk J de Jong, Pieter C Stokkers, Rinse K Weersma, The NIDDK IBD Genetics Consortium, Yashoda Sharma, Mark S Silverberg, Judy H Cho, Jing Wu, Kathryn Roeder, Steven R Brant, L Phillip Schumm, Richard H Duerr, Marla C Dubinsky, Nicole L Glazer, Talin Haritunians, Andy Ippoliti, Gil Y Melmed, David S Siscovick, Eric A Vasiliauskas, Stephan R Targan, Vito Annese, Cisca Wijmenga, Sven Pettersson, Jerome I Rotter, Ramnik J Xavier, Mark J Daly, John D Rioux, Mark Seielstad

ABSTRACT

Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract with a complex genetic and environmental etiology. In an effort to identify genetic variation underlying ulcerative colitis risk, we present two distinct genome-wide association studies of ulcerative colitis and their joint analysis with a previously published scan, comprising, in aggregate, 2,693 individuals with ulcerative colitis and 6,791 control subjects. Fifty-nine SNPs from 14 independent loci attained an association significance of P < 10(-5). Seven of these loci exceeded genome-wide significance (P < 5 x 10(-8)). After testing an independent cohort of 2,009 cases of ulcerative colitis and 1,580 controls, we identified 13 loci that were significantly associated with ulcerative colitis (P < 5 x 10(-8)), including the immunoglobulin receptor gene FCGR2A, 5p15, 2p16 and ORMDL3 (orosomucoid1-like 3). We confirmed association with 14 previously identified ulcerative colitis susceptibility loci, and an analysis of acknowledged Crohn's disease loci showed that roughly half of the known Crohn's disease associations are shared with ulcerative colitis. These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis. More... »

PAGES

332

References to SciGraph publications

  • 2008-10. Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease in NATURE GENETICS
  • 2008-09. Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus in NATURE GENETICS
  • 2009-12. Common variants at five new loci associated with early-onset inflammatory bowel disease in NATURE GENETICS
  • 2008-07. Deubiquitylation and regulation of the immune response in NATURE REVIEWS IMMUNOLOGY
  • 2008-06. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease in NATURE GENETICS
  • 2008-08. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease in NATURE GENETICS
  • 2002-05. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins in GENOME BIOLOGY
  • 2008-03. Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis in MUCOSAL IMMUNOLOGY
  • 2009-12. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region in NATURE GENETICS
  • 2009-02. Ulcerative colitis–risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study in NATURE GENETICS
  • 2008-09. The endoplasmic reticulum stress response in immunity and autoimmunity in NATURE REVIEWS IMMUNOLOGY
  • 2007-07. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma in NATURE
  • 2008-11. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility in NATURE GENETICS
  • 2009-12. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population in NATURE GENETICS
  • 2008-06. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis in NATURE GENETICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.549

    DOI

    http://dx.doi.org/10.1038/ng.549

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1031272000

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/20228799


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Colitis, Ulcerative", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Predisposition to Disease", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome-Wide Association Study", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Membrane Proteins", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Meta-Analysis as Topic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polymorphism, Single Nucleotide", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Receptors, IgG", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "McGovern", 
            "givenName": "Dermot P B", 
            "id": "sg:person.012743332661.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012743332661.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gardet", 
            "givenName": "Agn\u00e8s", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.24381.3c", 
              "name": [
                "Department for Clinical Science Intervention and Technology, Karolinska Institutet and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "T\u00f6rkvist", 
            "givenName": "Leif", 
            "id": "sg:person.0610736154.53", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610736154.53"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University Health Centre", 
              "id": "https://www.grid.ac/institutes/grid.63984.30", 
              "name": [
                "Universit\u00e9 de Montr\u00e9al and the Montreal Heart Institute, Research Center, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goyette", 
            "givenName": "Philippe", 
            "id": "sg:person.01263200673.64", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263200673.64"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Essers", 
            "givenName": "Jonah", 
            "id": "sg:person.01222216464.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222216464.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Taylor", 
            "givenName": "Kent D", 
            "id": "sg:person.010452447462.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010452447462.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Neale", 
            "givenName": "Benjamin M", 
            "id": "sg:person.014377465057.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377465057.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Human Genetics, Genome Institute of Singapore, Singapore."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ong", 
            "givenName": "Rick T H", 
            "id": "sg:person.013371472702.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013371472702.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University Health Centre", 
              "id": "https://www.grid.ac/institutes/grid.63984.30", 
              "name": [
                "Universit\u00e9 de Montr\u00e9al and the Montreal Heart Institute, Research Center, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Lagac\u00e9", 
            "givenName": "Caroline", 
            "id": "sg:person.01071365321.23", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071365321.23"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Li", 
            "givenName": "Chun", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Green", 
            "givenName": "Todd", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Stevens", 
            "givenName": "Christine R", 
            "id": "sg:person.01146571421.48", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146571421.48"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University Health Centre", 
              "id": "https://www.grid.ac/institutes/grid.63984.30", 
              "name": [
                "Universit\u00e9 de Montr\u00e9al and the Montreal Heart Institute, Research Center, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Beauchamp", 
            "givenName": "Claudine", 
            "id": "sg:person.0753104744.74", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753104744.74"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Fleshner", 
            "givenName": "Phillip R", 
            "id": "sg:person.010041616547.94", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010041616547.94"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Uppsala University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.412354.5", 
              "name": [
                "Department of Medical Sciences, Gastroenterology Research Group, Uppsala University Hospital, Uppsala, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Carlson", 
            "givenName": "Marie", 
            "id": "sg:person.01124051665.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124051665.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska Institute", 
              "id": "https://www.grid.ac/institutes/grid.4714.6", 
              "name": [
                "Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "D'Amato", 
            "givenName": "Mauro", 
            "id": "sg:person.013034560020.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013034560020.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "\u00d6rebro University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.412367.5", 
              "name": [
                "Division of Gastroenterology, Department of Internal Medicine, \u00d6rebro University Hospital, \u00d6rebro, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Halfvarson", 
            "givenName": "Jonas", 
            "id": "sg:person.0773277754.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773277754.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Genome Institute of Singapore", 
              "id": "https://www.grid.ac/institutes/grid.418377.e", 
              "name": [
                "Infectious Diseases, Genome Institute of Singapore, Singapore."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hibberd", 
            "givenName": "Martin L", 
            "id": "sg:person.0605725430.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605725430.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.24381.3c", 
              "name": [
                "Department of Medicine, and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "L\u00f6rdal", 
            "givenName": "Mikael", 
            "id": "sg:person.01202377267.89", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202377267.89"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska University Hospital", 
              "id": "https://www.grid.ac/institutes/grid.24381.3c", 
              "name": [
                "Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Padyukov", 
            "givenName": "Leonid", 
            "id": "sg:person.0745177357.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745177357.18"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Casa Sollievo della Sofferenza", 
              "id": "https://www.grid.ac/institutes/grid.413503.0", 
              "name": [
                "Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Andriulli", 
            "givenName": "Angelo", 
            "id": "sg:person.0731565272.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731565272.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Casa Sollievo della Sofferenza", 
              "id": "https://www.grid.ac/institutes/grid.413503.0", 
              "name": [
                "Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Colombo", 
            "givenName": "Elisabetta", 
            "id": "sg:person.0606364272.16", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606364272.16"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Casa Sollievo della Sofferenza", 
              "id": "https://www.grid.ac/institutes/grid.413503.0", 
              "name": [
                "Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Latiano", 
            "givenName": "Anna", 
            "id": "sg:person.0602015303.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602015303.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Casa Sollievo della Sofferenza", 
              "id": "https://www.grid.ac/institutes/grid.413503.0", 
              "name": [
                "Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Palmieri", 
            "givenName": "Orazio", 
            "id": "sg:person.0735034251.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735034251.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Hospitalier de l\u2019Universit\u00e9 de Montr\u00e9al", 
              "id": "https://www.grid.ac/institutes/grid.410559.c", 
              "name": [
                "Universit\u00e9 de Montr\u00e9al and Centre Hospitalier Universitaire de l'Universit\u00e9 de Montr\u00e9al, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Bernard", 
            "givenName": "Edmond-Jean", 
            "id": "sg:person.0744013567.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744013567.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Centre Hospitalier Universitaire Sainte-Justine", 
              "id": "https://www.grid.ac/institutes/grid.411418.9", 
              "name": [
                "Department of Gastroenterology, H\u00f4pital Sainte-Justine, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Deslandres", 
            "givenName": "Colette", 
            "id": "sg:person.01165201714.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165201714.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Leiden University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.10419.3d", 
              "name": [
                "Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hommes", 
            "givenName": "Daan W", 
            "id": "sg:person.015644561144.75", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015644561144.75"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Radboud University Nijmegen Medical Centre", 
              "id": "https://www.grid.ac/institutes/grid.10417.33", 
              "name": [
                "Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "de Jong", 
            "givenName": "Dirk J", 
            "id": "sg:person.01077446114.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077446114.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Academic Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5650.6", 
              "name": [
                "Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Stokkers", 
            "givenName": "Pieter C", 
            "id": "sg:person.01207560142.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207560142.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Weersma", 
            "givenName": "Rinse K", 
            "id": "sg:person.01346343347.18", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346343347.18"
            ], 
            "type": "Person"
          }, 
          {
            "familyName": "Consortium", 
            "givenName": "The NIDDK IBD Genetics", 
            "id": "sg:person.011015600441.22", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011015600441.22"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Yale University", 
              "id": "https://www.grid.ac/institutes/grid.47100.32", 
              "name": [
                "Section of Digestive Diseases, Department of Medicine, Yale University, New Haven, Connecticut, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Sharma", 
            "givenName": "Yashoda", 
            "id": "sg:person.0762727372.49", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762727372.49"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Toronto", 
              "id": "https://www.grid.ac/institutes/grid.17063.33", 
              "name": [
                "Mount Sinai Hospital Inflammatory Bowel Disease Group, University of Toronto, Toronto, Ontario, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Silverberg", 
            "givenName": "Mark S", 
            "id": "sg:person.01262212013.68", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262212013.68"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Yale University", 
              "id": "https://www.grid.ac/institutes/grid.47100.32", 
              "name": [
                "Section of Digestive Diseases, Department of Medicine, Yale University, New Haven, Connecticut, USA.", 
                "Department of Genetics, Yale University, New Haven, Connecticut, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Cho", 
            "givenName": "Judy H", 
            "id": "sg:person.011054712507.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011054712507.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Carnegie Mellon University", 
              "id": "https://www.grid.ac/institutes/grid.147455.6", 
              "name": [
                "Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wu", 
            "givenName": "Jing", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Carnegie Mellon University", 
              "id": "https://www.grid.ac/institutes/grid.147455.6", 
              "name": [
                "Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Roeder", 
            "givenName": "Kathryn", 
            "id": "sg:person.07620764017.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07620764017.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Johns Hopkins University", 
              "id": "https://www.grid.ac/institutes/grid.21107.35", 
              "name": [
                "Johns Hopkins University School of Medicine, Department of Medicine, and Johns Hopkins University Bloomberg School of Public Health, Department of Epidemiology, Baltimore, Maryland, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Brant", 
            "givenName": "Steven R", 
            "id": "sg:person.016644232277.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016644232277.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Chicago", 
              "id": "https://www.grid.ac/institutes/grid.170205.1", 
              "name": [
                "Department of Health Studies, University of Chicago, Chicago, Illinois, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Schumm", 
            "givenName": "L Phillip", 
            "id": "sg:person.01071255313.27", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071255313.27"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Pittsburgh", 
              "id": "https://www.grid.ac/institutes/grid.21925.3d", 
              "name": [
                "Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, and Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Duerr", 
            "givenName": "Richard H", 
            "id": "sg:person.010100255137.24", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010100255137.24"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Dubinsky", 
            "givenName": "Marla C", 
            "id": "sg:person.01312374137.43", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312374137.43"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Washington", 
              "id": "https://www.grid.ac/institutes/grid.34477.33", 
              "name": [
                "Cardiovascular Health Research Unit, Departments of Epidemiology and General Medicine, University of Washington, Seattle, Washington, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Glazer", 
            "givenName": "Nicole L", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Haritunians", 
            "givenName": "Talin", 
            "id": "sg:person.01304165677.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304165677.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ippoliti", 
            "givenName": "Andy", 
            "id": "sg:person.010740716337.20", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010740716337.20"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Melmed", 
            "givenName": "Gil Y", 
            "id": "sg:person.01352611136.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352611136.13"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Washington", 
              "id": "https://www.grid.ac/institutes/grid.34477.33", 
              "name": [
                "Cardiovascular Health Research Unit, Departments of Epidemiology and General Medicine, University of Washington, Seattle, Washington, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Siscovick", 
            "givenName": "David S", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vasiliauskas", 
            "givenName": "Eric A", 
            "id": "sg:person.011627077602.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011627077602.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Targan", 
            "givenName": "Stephan R", 
            "id": "sg:person.01074661215.00", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074661215.00"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Casa Sollievo della Sofferenza", 
              "id": "https://www.grid.ac/institutes/grid.413503.0", 
              "name": [
                "Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Annese", 
            "givenName": "Vito", 
            "id": "sg:person.0655214656.73", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655214656.73"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Groningen", 
              "id": "https://www.grid.ac/institutes/grid.4830.f", 
              "name": [
                "Department of Genetics, University Medical Center Groningen and Groningen University, Groningen, The Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wijmenga", 
            "givenName": "Cisca", 
            "id": "sg:person.01372510466.28", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372510466.28"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Singapore General Hospital", 
              "id": "https://www.grid.ac/institutes/grid.163555.1", 
              "name": [
                "Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.", 
                "Laboratory of Inflammation Biology, Singapore General Hospital, Singapore."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pettersson", 
            "givenName": "Sven", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Cedars-Sinai Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.50956.3f", 
              "name": [
                "Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rotter", 
            "givenName": "Jerome I", 
            "id": "sg:person.012264440652.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012264440652.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.", 
                "The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Xavier", 
            "givenName": "Ramnik J", 
            "id": "sg:person.0717130066.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717130066.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.", 
                "The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Daly", 
            "givenName": "Mark J", 
            "id": "sg:person.011517303117.07", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011517303117.07"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "McGill University Health Centre", 
              "id": "https://www.grid.ac/institutes/grid.63984.30", 
              "name": [
                "Universit\u00e9 de Montr\u00e9al and the Montreal Heart Institute, Research Center, Montr\u00e9al, Qu\u00e9bec, Canada."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rioux", 
            "givenName": "John D", 
            "id": "sg:person.01266053113.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266053113.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of California, San Francisco", 
              "id": "https://www.grid.ac/institutes/grid.266102.1", 
              "name": [
                "Human Genetics, Genome Institute of Singapore, Singapore.", 
                "Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.", 
                "Institute for Human Genetics, University of California San Fransisco, San Francisco, California, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Seielstad", 
            "givenName": "Mark", 
            "id": "sg:person.01124101671.13", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124101671.13"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/ng.221", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000435695", 
              "https://doi.org/10.1038/ng.221"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2009.08.007", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006057593"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.482", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007226853", 
              "https://doi.org/10.1038/ng.482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.482", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007226853", 
              "https://doi.org/10.1038/ng.482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa0810440", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007392898"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.275", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009732380", 
              "https://doi.org/10.1038/ng.275"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature06014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014505872", 
              "https://doi.org/10.1038/nature06014"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016974490", 
              "https://doi.org/10.1038/ng.145"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa073491", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1017852529"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.148", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018520629", 
              "https://doi.org/10.1038/ng.148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.483", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018950731", 
              "https://doi.org/10.1038/ng.483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.483", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018950731", 
              "https://doi.org/10.1038/ng.483"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/519795", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019061180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/ddn288", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022365148"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/mi.2007.15", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024892825", 
              "https://doi.org/10.1038/mi.2007.15"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1186/gb-2002-3-6-research0027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025513631", 
              "https://doi.org/10.1186/gb-2002-3-6-research0027"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2008.03.016", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1026192808"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/gut.2008.169052", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027479082"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0000691", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032680038"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri2359", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032995817", 
              "https://doi.org/10.1038/nri2359"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.175", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035894615", 
              "https://doi.org/10.1038/ng.175"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.203", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039303467", 
              "https://doi.org/10.1038/ng.203"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043158572", 
              "https://doi.org/10.1038/ng.200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20855", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044362423"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ibd.20855", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044362423"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.489", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047391697", 
              "https://doi.org/10.1038/ng.489"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.489", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047391697", 
              "https://doi.org/10.1038/ng.489"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1194/jlr.r800033-jlr200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047556697"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nri2337", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048707274", 
              "https://doi.org/10.1038/nri2337"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1089/ars.2008.2391", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059230960"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://app.dimensions.ai/details/publication/pub.1074654647", 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2010-04", 
        "datePublishedReg": "2010-04-01", 
        "description": "Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract with a complex genetic and environmental etiology. In an effort to identify genetic variation underlying ulcerative colitis risk, we present two distinct genome-wide association studies of ulcerative colitis and their joint analysis with a previously published scan, comprising, in aggregate, 2,693 individuals with ulcerative colitis and 6,791 control subjects. Fifty-nine SNPs from 14 independent loci attained an association significance of P < 10(-5). Seven of these loci exceeded genome-wide significance (P < 5 x 10(-8)). After testing an independent cohort of 2,009 cases of ulcerative colitis and 1,580 controls, we identified 13 loci that were significantly associated with ulcerative colitis (P < 5 x 10(-8)), including the immunoglobulin receptor gene FCGR2A, 5p15, 2p16 and ORMDL3 (orosomucoid1-like 3). We confirmed association with 14 previously identified ulcerative colitis susceptibility loci, and an analysis of acknowledged Crohn's disease loci showed that roughly half of the known Crohn's disease associations are shared with ulcerative colitis. These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis.", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/ng.549", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.2690022", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2438997", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430117", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2541401", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2435157", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2439002", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690024", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2695793", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2429985", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430172", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2499878", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430033", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2573090", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2498015", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2497353", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430170", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690023", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2439028", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2691844", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2424008", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690020", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690021", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430025", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430174", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690017", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2436126", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2668586", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430169", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430171", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690019", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430167", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430176", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2609719", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430173", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2430175", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1103138", 
            "issn": [
              "1061-4036", 
              "1546-1718"
            ], 
            "name": "Nature Genetics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "4", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "42"
          }
        ], 
        "name": "Genome-wide association identifies multiple ulcerative colitis susceptibility loci", 
        "pagination": "332", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "94f9a4ceb2155639b4a90192b70af18e0ad221876c53a51cdaf16672a8252484"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "20228799"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9216904"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ng.549"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1031272000"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ng.549", 
          "https://app.dimensions.ai/details/publication/pub.1031272000"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-11T10:17", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000348_0000000348/records_54310_00000000.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "https://www.nature.com/articles/ng.549"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.549'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.549'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.549'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.549'


     

    This table displays all metadata directly associated to this object as RDF triples.

    725 TRIPLES      21 PREDICATES      64 URIs      29 LITERALS      17 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ng.549 schema:about N01ae2da1d2794525a1f84b241e9cbdd3
    2 N021572d40aaa4f9fb440526d94e80e1a
    3 N7069956b99174b4c96f5042efc0b6ba6
    4 N8df39632be1b4be084eb419b1f7ff800
    5 N9bb5f34199d7408f88c73eb661c8cb69
    6 Nb055909fcacd409fb17a34dfffb578ee
    7 Nb13373b264c641c783fa79d361ac9bca
    8 Nf7c6841c0aec4446b3842e2a22a9456f
    9 anzsrc-for:06
    10 anzsrc-for:0604
    11 schema:author Nb07fb7a8128d4cd6ba28680bce99be83
    12 schema:citation sg:pub.10.1038/mi.2007.15
    13 sg:pub.10.1038/nature06014
    14 sg:pub.10.1038/ng.145
    15 sg:pub.10.1038/ng.148
    16 sg:pub.10.1038/ng.175
    17 sg:pub.10.1038/ng.200
    18 sg:pub.10.1038/ng.203
    19 sg:pub.10.1038/ng.221
    20 sg:pub.10.1038/ng.275
    21 sg:pub.10.1038/ng.482
    22 sg:pub.10.1038/ng.483
    23 sg:pub.10.1038/ng.489
    24 sg:pub.10.1038/nri2337
    25 sg:pub.10.1038/nri2359
    26 sg:pub.10.1186/gb-2002-3-6-research0027
    27 https://app.dimensions.ai/details/publication/pub.1074654647
    28 https://doi.org/10.1002/ibd.20855
    29 https://doi.org/10.1016/j.ajhg.2008.03.016
    30 https://doi.org/10.1016/j.ajhg.2009.08.007
    31 https://doi.org/10.1056/nejmoa073491
    32 https://doi.org/10.1056/nejmoa0810440
    33 https://doi.org/10.1086/519795
    34 https://doi.org/10.1089/ars.2008.2391
    35 https://doi.org/10.1093/hmg/ddn288
    36 https://doi.org/10.1136/gut.2008.169052
    37 https://doi.org/10.1194/jlr.r800033-jlr200
    38 https://doi.org/10.1371/journal.pone.0000691
    39 schema:datePublished 2010-04
    40 schema:datePublishedReg 2010-04-01
    41 schema:description Ulcerative colitis is a chronic, relapsing inflammatory condition of the gastrointestinal tract with a complex genetic and environmental etiology. In an effort to identify genetic variation underlying ulcerative colitis risk, we present two distinct genome-wide association studies of ulcerative colitis and their joint analysis with a previously published scan, comprising, in aggregate, 2,693 individuals with ulcerative colitis and 6,791 control subjects. Fifty-nine SNPs from 14 independent loci attained an association significance of P < 10(-5). Seven of these loci exceeded genome-wide significance (P < 5 x 10(-8)). After testing an independent cohort of 2,009 cases of ulcerative colitis and 1,580 controls, we identified 13 loci that were significantly associated with ulcerative colitis (P < 5 x 10(-8)), including the immunoglobulin receptor gene FCGR2A, 5p15, 2p16 and ORMDL3 (orosomucoid1-like 3). We confirmed association with 14 previously identified ulcerative colitis susceptibility loci, and an analysis of acknowledged Crohn's disease loci showed that roughly half of the known Crohn's disease associations are shared with ulcerative colitis. These data implicate approximately 30 loci in ulcerative colitis, thereby providing insight into disease pathogenesis.
    42 schema:genre research_article
    43 schema:inLanguage en
    44 schema:isAccessibleForFree true
    45 schema:isPartOf N3f6c31eb24ae4b168f8101e8a2131d21
    46 N57b66ea46dc5410686e31c131151bed7
    47 sg:journal.1103138
    48 schema:name Genome-wide association identifies multiple ulcerative colitis susceptibility loci
    49 schema:pagination 332
    50 schema:productId N0eb7b52b2a674be2a25075fadb90ac4a
    51 N733b96f8ce6e4f45a8faee1b80a5db1c
    52 N9c3ca945305b4c73a6e81a88024a81b0
    53 Nb317e0d1ee7841ad9d2fc12301316cb0
    54 Nf0acec306cef449389404688e2befa4f
    55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031272000
    56 https://doi.org/10.1038/ng.549
    57 schema:sdDatePublished 2019-04-11T10:17
    58 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    59 schema:sdPublisher N89c5d6d701de40d88525a45fedb0dd63
    60 schema:url https://www.nature.com/articles/ng.549
    61 sgo:license sg:explorer/license/
    62 sgo:sdDataset articles
    63 rdf:type schema:ScholarlyArticle
    64 N01ae2da1d2794525a1f84b241e9cbdd3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    65 schema:name Meta-Analysis as Topic
    66 rdf:type schema:DefinedTerm
    67 N021572d40aaa4f9fb440526d94e80e1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    68 schema:name Genetic Predisposition to Disease
    69 rdf:type schema:DefinedTerm
    70 N0339abdc415048bba50c9da5d839b03e schema:affiliation Nfcd39b80263d4c0db03bedfc2cf430a7
    71 schema:familyName Gardet
    72 schema:givenName Agnès
    73 rdf:type schema:Person
    74 N0471b6dddbc9429a98ab8d7a3ffb7a9c rdf:first sg:person.010740716337.20
    75 rdf:rest Nd5f1ce1789bf4cb483b8f8964237846c
    76 N05a1e49c5efb4084ba9aae7234b84a21 rdf:first sg:person.014377465057.81
    77 rdf:rest Nd599d7076a7f497490e372379de877f1
    78 N06e9b008e3264c649c45e09b2c066337 rdf:first sg:person.0773277754.13
    79 rdf:rest N0b775973a94740a7a71b3aa922fc8763
    80 N08a10a8510c14ab297a460d12eac6242 rdf:first sg:person.0655214656.73
    81 rdf:rest Ne9fa50aa53a84a91a7f9603d4fe8bee1
    82 N090ce50ff9824c88a4dd0fc831baa651 rdf:first sg:person.0606364272.16
    83 rdf:rest N9379d993f1b44835aa6c136ecf15e8d4
    84 N0b775973a94740a7a71b3aa922fc8763 rdf:first sg:person.0605725430.68
    85 rdf:rest N89ec556bce404fc597007987ce0595fe
    86 N0ba7c651f70f4cb2bdd9becef197644f rdf:first sg:person.01262212013.68
    87 rdf:rest Na1b2e94e2c614d90b65c57d7419f4a45
    88 N0eb7b52b2a674be2a25075fadb90ac4a schema:name dimensions_id
    89 schema:value pub.1031272000
    90 rdf:type schema:PropertyValue
    91 N28db4b2861b746979c365a5c8ac4758f rdf:first sg:person.01207560142.25
    92 rdf:rest N5ec48dc1c2f544c8925f4f5ea9365b90
    93 N2d09c9f63a3a4f91b1c9a87c8f2779b9 rdf:first Ne83f28e6463b40a0b9c996dd2853e849
    94 rdf:rest Nd3e0a339051743c8b35843bd1bdc0ff5
    95 N3f6c31eb24ae4b168f8101e8a2131d21 schema:issueNumber 4
    96 rdf:type schema:PublicationIssue
    97 N437165b266744cecb4c58d38a2aa59b9 schema:affiliation https://www.grid.ac/institutes/grid.147455.6
    98 schema:familyName Wu
    99 schema:givenName Jing
    100 rdf:type schema:Person
    101 N57b66ea46dc5410686e31c131151bed7 schema:volumeNumber 42
    102 rdf:type schema:PublicationVolume
    103 N5ec48dc1c2f544c8925f4f5ea9365b90 rdf:first sg:person.01346343347.18
    104 rdf:rest Nb4aa39f4f760418aa0268e6db7d97321
    105 N63ada526be724ee38e044d829275c376 rdf:first sg:person.01124101671.13
    106 rdf:rest rdf:nil
    107 N65336091217f4a0ba9b11bdcc5265054 rdf:first sg:person.0762727372.49
    108 rdf:rest N0ba7c651f70f4cb2bdd9becef197644f
    109 N658e776816a04b89b768ea8e1bae21b0 schema:affiliation https://www.grid.ac/institutes/grid.163555.1
    110 schema:familyName Pettersson
    111 schema:givenName Sven
    112 rdf:type schema:Person
    113 N6601373c1a6e41e3bcca62caaba85325 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    114 schema:familyName Green
    115 schema:givenName Todd
    116 rdf:type schema:Person
    117 N66f0b27b3b944a68b50ee4d020ff3e80 rdf:first sg:person.01071365321.23
    118 rdf:rest N2d09c9f63a3a4f91b1c9a87c8f2779b9
    119 N6a003338a74a4a85ab4ef41981203975 rdf:first sg:person.01312374137.43
    120 rdf:rest Nd8ac5cc2c967457988cf1908832e5f2e
    121 N6ba47a7443024e8f899a594d4b12a4a6 rdf:first sg:person.0745177357.18
    122 rdf:rest N6c0d4d854e604db6ad60f497d0f30062
    123 N6c0d4d854e604db6ad60f497d0f30062 rdf:first sg:person.0731565272.40
    124 rdf:rest N090ce50ff9824c88a4dd0fc831baa651
    125 N6f5ba589d40d461f850d95f7da3e2e7d rdf:first sg:person.01124051665.88
    126 rdf:rest N94234d8f49844d8ea766f3d78cbc1e16
    127 N6f951a0f1cf947bd87b6ef5fb74c04e9 schema:name Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
    128 rdf:type schema:Organization
    129 N7069956b99174b4c96f5042efc0b6ba6 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    130 schema:name Colitis, Ulcerative
    131 rdf:type schema:DefinedTerm
    132 N718fbe320e81438ca905902914a4241e rdf:first sg:person.01146571421.48
    133 rdf:rest Nc5820525a62c4e62900dcb356cf9f757
    134 N721dbd8352624b48bc41c62fe3a457f3 rdf:first sg:person.0735034251.49
    135 rdf:rest Nc7914ea0586346a59ef0419a6511bd18
    136 N727dedba70664d239a656e418adaa701 schema:name Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    137 rdf:type schema:Organization
    138 N733b96f8ce6e4f45a8faee1b80a5db1c schema:name readcube_id
    139 schema:value 94f9a4ceb2155639b4a90192b70af18e0ad221876c53a51cdaf16672a8252484
    140 rdf:type schema:PropertyValue
    141 N76cead87eb10471997e4ae8a9211bd87 schema:name Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    142 rdf:type schema:Organization
    143 N76d8e599c1834be99b193ee139267e32 rdf:first sg:person.010452447462.48
    144 rdf:rest N05a1e49c5efb4084ba9aae7234b84a21
    145 N85ef245a4e6d45e1becbd43ca6b245ce rdf:first sg:person.011517303117.07
    146 rdf:rest Na1929218e5e84faea09e0ee71808efbc
    147 N878f46c6af9e4c1fbd6f3c06c1b44ee0 rdf:first sg:person.01222216464.10
    148 rdf:rest N76d8e599c1834be99b193ee139267e32
    149 N889f2cb1b0d2427a9efd3a02ccc99499 rdf:first sg:person.01071255313.27
    150 rdf:rest Na1abf1a879d64ece8eb31a5aa483641e
    151 N892836122cf4448e8d429e3a40335028 rdf:first sg:person.07620764017.88
    152 rdf:rest Nd4083afb66bd4c9e93a672e7822b7839
    153 N89c5d6d701de40d88525a45fedb0dd63 schema:name Springer Nature - SN SciGraph project
    154 rdf:type schema:Organization
    155 N89ec556bce404fc597007987ce0595fe rdf:first sg:person.01202377267.89
    156 rdf:rest N6ba47a7443024e8f899a594d4b12a4a6
    157 N8b22981332924a4cbdbb55232df710ed rdf:first sg:person.01074661215.00
    158 rdf:rest N08a10a8510c14ab297a460d12eac6242
    159 N8c1155e69f614651b5d137a1fd61767b schema:name Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    160 rdf:type schema:Organization
    161 N8df39632be1b4be084eb419b1f7ff800 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    162 schema:name Humans
    163 rdf:type schema:DefinedTerm
    164 N90611b8faffd4fb1816c9eed81376870 rdf:first sg:person.0610736154.53
    165 rdf:rest Nd5b2a3cd0f26400c8cebef8403df998c
    166 N9201e31ca48e4ac3a4f8a774e1359b63 rdf:first N437165b266744cecb4c58d38a2aa59b9
    167 rdf:rest N892836122cf4448e8d429e3a40335028
    168 N9379d993f1b44835aa6c136ecf15e8d4 rdf:first sg:person.0602015303.44
    169 rdf:rest N721dbd8352624b48bc41c62fe3a457f3
    170 N94234d8f49844d8ea766f3d78cbc1e16 rdf:first sg:person.013034560020.81
    171 rdf:rest N06e9b008e3264c649c45e09b2c066337
    172 N94275720e18d4865bf9e82fd2f168f41 rdf:first sg:person.011627077602.39
    173 rdf:rest N8b22981332924a4cbdbb55232df710ed
    174 N9bb5f34199d7408f88c73eb661c8cb69 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    175 schema:name Receptors, IgG
    176 rdf:type schema:DefinedTerm
    177 N9c3ca945305b4c73a6e81a88024a81b0 schema:name nlm_unique_id
    178 schema:value 9216904
    179 rdf:type schema:PropertyValue
    180 N9dffa4e748d04ec18e5e140ba0cd0165 rdf:first sg:person.010041616547.94
    181 rdf:rest N6f5ba589d40d461f850d95f7da3e2e7d
    182 Na1929218e5e84faea09e0ee71808efbc rdf:first sg:person.01266053113.52
    183 rdf:rest N63ada526be724ee38e044d829275c376
    184 Na1abf1a879d64ece8eb31a5aa483641e rdf:first sg:person.010100255137.24
    185 rdf:rest N6a003338a74a4a85ab4ef41981203975
    186 Na1b2e94e2c614d90b65c57d7419f4a45 rdf:first sg:person.011054712507.07
    187 rdf:rest N9201e31ca48e4ac3a4f8a774e1359b63
    188 Nb055909fcacd409fb17a34dfffb578ee schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    189 schema:name Genome-Wide Association Study
    190 rdf:type schema:DefinedTerm
    191 Nb07fb7a8128d4cd6ba28680bce99be83 rdf:first sg:person.012743332661.02
    192 rdf:rest Nf8e94c4d41964edc91eeaa93405fcf3c
    193 Nb13373b264c641c783fa79d361ac9bca schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    194 schema:name Membrane Proteins
    195 rdf:type schema:DefinedTerm
    196 Nb317e0d1ee7841ad9d2fc12301316cb0 schema:name pubmed_id
    197 schema:value 20228799
    198 rdf:type schema:PropertyValue
    199 Nb4aa39f4f760418aa0268e6db7d97321 rdf:first sg:person.011015600441.22
    200 rdf:rest N65336091217f4a0ba9b11bdcc5265054
    201 Nbc7861add5cb42b180df0d28318854f5 rdf:first N658e776816a04b89b768ea8e1bae21b0
    202 rdf:rest Ned55386b9c4343b78a91369b56fb39ae
    203 Nc25035f6d5c947008ef0ecce9abb6f68 rdf:first Nfa7a08fdaaf44963be4c3059f1227e52
    204 rdf:rest N94275720e18d4865bf9e82fd2f168f41
    205 Nc5820525a62c4e62900dcb356cf9f757 rdf:first sg:person.0753104744.74
    206 rdf:rest N9dffa4e748d04ec18e5e140ba0cd0165
    207 Nc646482944734c5a9b924f1ef3f32413 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
    208 schema:familyName Glazer
    209 schema:givenName Nicole L
    210 rdf:type schema:Person
    211 Nc7914ea0586346a59ef0419a6511bd18 rdf:first sg:person.0744013567.49
    212 rdf:rest Neaf056b685e0400a86e23330841fee3e
    213 Ncf5f9db32468489ab8c95fcdcf244f0e rdf:first sg:person.0717130066.82
    214 rdf:rest N85ef245a4e6d45e1becbd43ca6b245ce
    215 Nd3e0a339051743c8b35843bd1bdc0ff5 rdf:first N6601373c1a6e41e3bcca62caaba85325
    216 rdf:rest N718fbe320e81438ca905902914a4241e
    217 Nd4083afb66bd4c9e93a672e7822b7839 rdf:first sg:person.016644232277.39
    218 rdf:rest N889f2cb1b0d2427a9efd3a02ccc99499
    219 Nd599d7076a7f497490e372379de877f1 rdf:first sg:person.013371472702.22
    220 rdf:rest N66f0b27b3b944a68b50ee4d020ff3e80
    221 Nd5b2a3cd0f26400c8cebef8403df998c rdf:first sg:person.01263200673.64
    222 rdf:rest N878f46c6af9e4c1fbd6f3c06c1b44ee0
    223 Nd5f1ce1789bf4cb483b8f8964237846c rdf:first sg:person.01352611136.13
    224 rdf:rest Nc25035f6d5c947008ef0ecce9abb6f68
    225 Nd8ac5cc2c967457988cf1908832e5f2e rdf:first Nc646482944734c5a9b924f1ef3f32413
    226 rdf:rest Nf21ae6b7809e416a81ea50df4efebc68
    227 Nde489f92f1584b1a9baaa69e68e0a85b rdf:first sg:person.015644561144.75
    228 rdf:rest Nebb00cce61da4f0fab6008fd8966217e
    229 Ne83f28e6463b40a0b9c996dd2853e849 schema:affiliation N727dedba70664d239a656e418adaa701
    230 schema:familyName Li
    231 schema:givenName Chun
    232 rdf:type schema:Person
    233 Ne9fa50aa53a84a91a7f9603d4fe8bee1 rdf:first sg:person.01372510466.28
    234 rdf:rest Nbc7861add5cb42b180df0d28318854f5
    235 Neaf056b685e0400a86e23330841fee3e rdf:first sg:person.01165201714.56
    236 rdf:rest Nde489f92f1584b1a9baaa69e68e0a85b
    237 Nebb00cce61da4f0fab6008fd8966217e rdf:first sg:person.01077446114.87
    238 rdf:rest N28db4b2861b746979c365a5c8ac4758f
    239 Ned55386b9c4343b78a91369b56fb39ae rdf:first sg:person.012264440652.05
    240 rdf:rest Ncf5f9db32468489ab8c95fcdcf244f0e
    241 Nf0acec306cef449389404688e2befa4f schema:name doi
    242 schema:value 10.1038/ng.549
    243 rdf:type schema:PropertyValue
    244 Nf21ae6b7809e416a81ea50df4efebc68 rdf:first sg:person.01304165677.44
    245 rdf:rest N0471b6dddbc9429a98ab8d7a3ffb7a9c
    246 Nf7c6841c0aec4446b3842e2a22a9456f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    247 schema:name Polymorphism, Single Nucleotide
    248 rdf:type schema:DefinedTerm
    249 Nf8e94c4d41964edc91eeaa93405fcf3c rdf:first N0339abdc415048bba50c9da5d839b03e
    250 rdf:rest N90611b8faffd4fb1816c9eed81376870
    251 Nfa7a08fdaaf44963be4c3059f1227e52 schema:affiliation https://www.grid.ac/institutes/grid.34477.33
    252 schema:familyName Siscovick
    253 schema:givenName David S
    254 rdf:type schema:Person
    255 Nfcd39b80263d4c0db03bedfc2cf430a7 schema:name Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    256 rdf:type schema:Organization
    257 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    258 schema:name Biological Sciences
    259 rdf:type schema:DefinedTerm
    260 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    261 schema:name Genetics
    262 rdf:type schema:DefinedTerm
    263 sg:grant.2424008 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    264 rdf:type schema:MonetaryGrant
    265 sg:grant.2429985 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    266 rdf:type schema:MonetaryGrant
    267 sg:grant.2430025 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    268 rdf:type schema:MonetaryGrant
    269 sg:grant.2430033 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    270 rdf:type schema:MonetaryGrant
    271 sg:grant.2430117 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    272 rdf:type schema:MonetaryGrant
    273 sg:grant.2430167 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    274 rdf:type schema:MonetaryGrant
    275 sg:grant.2430169 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    276 rdf:type schema:MonetaryGrant
    277 sg:grant.2430170 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    278 rdf:type schema:MonetaryGrant
    279 sg:grant.2430171 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    280 rdf:type schema:MonetaryGrant
    281 sg:grant.2430172 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    282 rdf:type schema:MonetaryGrant
    283 sg:grant.2430173 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    284 rdf:type schema:MonetaryGrant
    285 sg:grant.2430174 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    286 rdf:type schema:MonetaryGrant
    287 sg:grant.2430175 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    288 rdf:type schema:MonetaryGrant
    289 sg:grant.2430176 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    290 rdf:type schema:MonetaryGrant
    291 sg:grant.2435157 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    292 rdf:type schema:MonetaryGrant
    293 sg:grant.2436126 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    294 rdf:type schema:MonetaryGrant
    295 sg:grant.2438997 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    296 rdf:type schema:MonetaryGrant
    297 sg:grant.2439002 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    298 rdf:type schema:MonetaryGrant
    299 sg:grant.2439028 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    300 rdf:type schema:MonetaryGrant
    301 sg:grant.2497353 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    302 rdf:type schema:MonetaryGrant
    303 sg:grant.2498015 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    304 rdf:type schema:MonetaryGrant
    305 sg:grant.2499878 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    306 rdf:type schema:MonetaryGrant
    307 sg:grant.2541401 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    308 rdf:type schema:MonetaryGrant
    309 sg:grant.2573090 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    310 rdf:type schema:MonetaryGrant
    311 sg:grant.2609719 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    312 rdf:type schema:MonetaryGrant
    313 sg:grant.2668586 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    314 rdf:type schema:MonetaryGrant
    315 sg:grant.2690017 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    316 rdf:type schema:MonetaryGrant
    317 sg:grant.2690019 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    318 rdf:type schema:MonetaryGrant
    319 sg:grant.2690020 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    320 rdf:type schema:MonetaryGrant
    321 sg:grant.2690021 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    322 rdf:type schema:MonetaryGrant
    323 sg:grant.2690022 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    324 rdf:type schema:MonetaryGrant
    325 sg:grant.2690023 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    326 rdf:type schema:MonetaryGrant
    327 sg:grant.2690024 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    328 rdf:type schema:MonetaryGrant
    329 sg:grant.2691844 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    330 rdf:type schema:MonetaryGrant
    331 sg:grant.2695793 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.549
    332 rdf:type schema:MonetaryGrant
    333 sg:journal.1103138 schema:issn 1061-4036
    334 1546-1718
    335 schema:name Nature Genetics
    336 rdf:type schema:Periodical
    337 sg:person.010041616547.94 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    338 schema:familyName Fleshner
    339 schema:givenName Phillip R
    340 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010041616547.94
    341 rdf:type schema:Person
    342 sg:person.010100255137.24 schema:affiliation https://www.grid.ac/institutes/grid.21925.3d
    343 schema:familyName Duerr
    344 schema:givenName Richard H
    345 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010100255137.24
    346 rdf:type schema:Person
    347 sg:person.010452447462.48 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    348 schema:familyName Taylor
    349 schema:givenName Kent D
    350 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010452447462.48
    351 rdf:type schema:Person
    352 sg:person.01071255313.27 schema:affiliation https://www.grid.ac/institutes/grid.170205.1
    353 schema:familyName Schumm
    354 schema:givenName L Phillip
    355 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071255313.27
    356 rdf:type schema:Person
    357 sg:person.01071365321.23 schema:affiliation https://www.grid.ac/institutes/grid.63984.30
    358 schema:familyName Lagacé
    359 schema:givenName Caroline
    360 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071365321.23
    361 rdf:type schema:Person
    362 sg:person.010740716337.20 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    363 schema:familyName Ippoliti
    364 schema:givenName Andy
    365 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010740716337.20
    366 rdf:type schema:Person
    367 sg:person.01074661215.00 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    368 schema:familyName Targan
    369 schema:givenName Stephan R
    370 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01074661215.00
    371 rdf:type schema:Person
    372 sg:person.01077446114.87 schema:affiliation https://www.grid.ac/institutes/grid.10417.33
    373 schema:familyName de Jong
    374 schema:givenName Dirk J
    375 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01077446114.87
    376 rdf:type schema:Person
    377 sg:person.011015600441.22 schema:familyName Consortium
    378 schema:givenName The NIDDK IBD Genetics
    379 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011015600441.22
    380 rdf:type schema:Person
    381 sg:person.011054712507.07 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
    382 schema:familyName Cho
    383 schema:givenName Judy H
    384 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011054712507.07
    385 rdf:type schema:Person
    386 sg:person.01124051665.88 schema:affiliation https://www.grid.ac/institutes/grid.412354.5
    387 schema:familyName Carlson
    388 schema:givenName Marie
    389 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124051665.88
    390 rdf:type schema:Person
    391 sg:person.01124101671.13 schema:affiliation https://www.grid.ac/institutes/grid.266102.1
    392 schema:familyName Seielstad
    393 schema:givenName Mark
    394 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01124101671.13
    395 rdf:type schema:Person
    396 sg:person.01146571421.48 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    397 schema:familyName Stevens
    398 schema:givenName Christine R
    399 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01146571421.48
    400 rdf:type schema:Person
    401 sg:person.011517303117.07 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    402 schema:familyName Daly
    403 schema:givenName Mark J
    404 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011517303117.07
    405 rdf:type schema:Person
    406 sg:person.011627077602.39 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    407 schema:familyName Vasiliauskas
    408 schema:givenName Eric A
    409 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011627077602.39
    410 rdf:type schema:Person
    411 sg:person.01165201714.56 schema:affiliation https://www.grid.ac/institutes/grid.411418.9
    412 schema:familyName Deslandres
    413 schema:givenName Colette
    414 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01165201714.56
    415 rdf:type schema:Person
    416 sg:person.01202377267.89 schema:affiliation https://www.grid.ac/institutes/grid.24381.3c
    417 schema:familyName Lördal
    418 schema:givenName Mikael
    419 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01202377267.89
    420 rdf:type schema:Person
    421 sg:person.01207560142.25 schema:affiliation https://www.grid.ac/institutes/grid.5650.6
    422 schema:familyName Stokkers
    423 schema:givenName Pieter C
    424 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207560142.25
    425 rdf:type schema:Person
    426 sg:person.01222216464.10 schema:affiliation N76cead87eb10471997e4ae8a9211bd87
    427 schema:familyName Essers
    428 schema:givenName Jonah
    429 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01222216464.10
    430 rdf:type schema:Person
    431 sg:person.012264440652.05 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    432 schema:familyName Rotter
    433 schema:givenName Jerome I
    434 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012264440652.05
    435 rdf:type schema:Person
    436 sg:person.01262212013.68 schema:affiliation https://www.grid.ac/institutes/grid.17063.33
    437 schema:familyName Silverberg
    438 schema:givenName Mark S
    439 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01262212013.68
    440 rdf:type schema:Person
    441 sg:person.01263200673.64 schema:affiliation https://www.grid.ac/institutes/grid.63984.30
    442 schema:familyName Goyette
    443 schema:givenName Philippe
    444 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263200673.64
    445 rdf:type schema:Person
    446 sg:person.01266053113.52 schema:affiliation https://www.grid.ac/institutes/grid.63984.30
    447 schema:familyName Rioux
    448 schema:givenName John D
    449 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01266053113.52
    450 rdf:type schema:Person
    451 sg:person.012743332661.02 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    452 schema:familyName McGovern
    453 schema:givenName Dermot P B
    454 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012743332661.02
    455 rdf:type schema:Person
    456 sg:person.013034560020.81 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
    457 schema:familyName D'Amato
    458 schema:givenName Mauro
    459 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013034560020.81
    460 rdf:type schema:Person
    461 sg:person.01304165677.44 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    462 schema:familyName Haritunians
    463 schema:givenName Talin
    464 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01304165677.44
    465 rdf:type schema:Person
    466 sg:person.01312374137.43 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    467 schema:familyName Dubinsky
    468 schema:givenName Marla C
    469 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01312374137.43
    470 rdf:type schema:Person
    471 sg:person.013371472702.22 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    472 schema:familyName Ong
    473 schema:givenName Rick T H
    474 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013371472702.22
    475 rdf:type schema:Person
    476 sg:person.01346343347.18 schema:affiliation N6f951a0f1cf947bd87b6ef5fb74c04e9
    477 schema:familyName Weersma
    478 schema:givenName Rinse K
    479 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01346343347.18
    480 rdf:type schema:Person
    481 sg:person.01352611136.13 schema:affiliation https://www.grid.ac/institutes/grid.50956.3f
    482 schema:familyName Melmed
    483 schema:givenName Gil Y
    484 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01352611136.13
    485 rdf:type schema:Person
    486 sg:person.01372510466.28 schema:affiliation https://www.grid.ac/institutes/grid.4830.f
    487 schema:familyName Wijmenga
    488 schema:givenName Cisca
    489 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01372510466.28
    490 rdf:type schema:Person
    491 sg:person.014377465057.81 schema:affiliation N8c1155e69f614651b5d137a1fd61767b
    492 schema:familyName Neale
    493 schema:givenName Benjamin M
    494 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014377465057.81
    495 rdf:type schema:Person
    496 sg:person.015644561144.75 schema:affiliation https://www.grid.ac/institutes/grid.10419.3d
    497 schema:familyName Hommes
    498 schema:givenName Daan W
    499 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015644561144.75
    500 rdf:type schema:Person
    501 sg:person.016644232277.39 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
    502 schema:familyName Brant
    503 schema:givenName Steven R
    504 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016644232277.39
    505 rdf:type schema:Person
    506 sg:person.0602015303.44 schema:affiliation https://www.grid.ac/institutes/grid.413503.0
    507 schema:familyName Latiano
    508 schema:givenName Anna
    509 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602015303.44
    510 rdf:type schema:Person
    511 sg:person.0605725430.68 schema:affiliation https://www.grid.ac/institutes/grid.418377.e
    512 schema:familyName Hibberd
    513 schema:givenName Martin L
    514 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0605725430.68
    515 rdf:type schema:Person
    516 sg:person.0606364272.16 schema:affiliation https://www.grid.ac/institutes/grid.413503.0
    517 schema:familyName Colombo
    518 schema:givenName Elisabetta
    519 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0606364272.16
    520 rdf:type schema:Person
    521 sg:person.0610736154.53 schema:affiliation https://www.grid.ac/institutes/grid.24381.3c
    522 schema:familyName Törkvist
    523 schema:givenName Leif
    524 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610736154.53
    525 rdf:type schema:Person
    526 sg:person.0655214656.73 schema:affiliation https://www.grid.ac/institutes/grid.413503.0
    527 schema:familyName Annese
    528 schema:givenName Vito
    529 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0655214656.73
    530 rdf:type schema:Person
    531 sg:person.0717130066.82 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    532 schema:familyName Xavier
    533 schema:givenName Ramnik J
    534 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0717130066.82
    535 rdf:type schema:Person
    536 sg:person.0731565272.40 schema:affiliation https://www.grid.ac/institutes/grid.413503.0
    537 schema:familyName Andriulli
    538 schema:givenName Angelo
    539 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0731565272.40
    540 rdf:type schema:Person
    541 sg:person.0735034251.49 schema:affiliation https://www.grid.ac/institutes/grid.413503.0
    542 schema:familyName Palmieri
    543 schema:givenName Orazio
    544 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735034251.49
    545 rdf:type schema:Person
    546 sg:person.0744013567.49 schema:affiliation https://www.grid.ac/institutes/grid.410559.c
    547 schema:familyName Bernard
    548 schema:givenName Edmond-Jean
    549 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0744013567.49
    550 rdf:type schema:Person
    551 sg:person.0745177357.18 schema:affiliation https://www.grid.ac/institutes/grid.24381.3c
    552 schema:familyName Padyukov
    553 schema:givenName Leonid
    554 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0745177357.18
    555 rdf:type schema:Person
    556 sg:person.0753104744.74 schema:affiliation https://www.grid.ac/institutes/grid.63984.30
    557 schema:familyName Beauchamp
    558 schema:givenName Claudine
    559 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0753104744.74
    560 rdf:type schema:Person
    561 sg:person.07620764017.88 schema:affiliation https://www.grid.ac/institutes/grid.147455.6
    562 schema:familyName Roeder
    563 schema:givenName Kathryn
    564 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07620764017.88
    565 rdf:type schema:Person
    566 sg:person.0762727372.49 schema:affiliation https://www.grid.ac/institutes/grid.47100.32
    567 schema:familyName Sharma
    568 schema:givenName Yashoda
    569 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0762727372.49
    570 rdf:type schema:Person
    571 sg:person.0773277754.13 schema:affiliation https://www.grid.ac/institutes/grid.412367.5
    572 schema:familyName Halfvarson
    573 schema:givenName Jonas
    574 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0773277754.13
    575 rdf:type schema:Person
    576 sg:pub.10.1038/mi.2007.15 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024892825
    577 https://doi.org/10.1038/mi.2007.15
    578 rdf:type schema:CreativeWork
    579 sg:pub.10.1038/nature06014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014505872
    580 https://doi.org/10.1038/nature06014
    581 rdf:type schema:CreativeWork
    582 sg:pub.10.1038/ng.145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016974490
    583 https://doi.org/10.1038/ng.145
    584 rdf:type schema:CreativeWork
    585 sg:pub.10.1038/ng.148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018520629
    586 https://doi.org/10.1038/ng.148
    587 rdf:type schema:CreativeWork
    588 sg:pub.10.1038/ng.175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035894615
    589 https://doi.org/10.1038/ng.175
    590 rdf:type schema:CreativeWork
    591 sg:pub.10.1038/ng.200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043158572
    592 https://doi.org/10.1038/ng.200
    593 rdf:type schema:CreativeWork
    594 sg:pub.10.1038/ng.203 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039303467
    595 https://doi.org/10.1038/ng.203
    596 rdf:type schema:CreativeWork
    597 sg:pub.10.1038/ng.221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000435695
    598 https://doi.org/10.1038/ng.221
    599 rdf:type schema:CreativeWork
    600 sg:pub.10.1038/ng.275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009732380
    601 https://doi.org/10.1038/ng.275
    602 rdf:type schema:CreativeWork
    603 sg:pub.10.1038/ng.482 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007226853
    604 https://doi.org/10.1038/ng.482
    605 rdf:type schema:CreativeWork
    606 sg:pub.10.1038/ng.483 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018950731
    607 https://doi.org/10.1038/ng.483
    608 rdf:type schema:CreativeWork
    609 sg:pub.10.1038/ng.489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047391697
    610 https://doi.org/10.1038/ng.489
    611 rdf:type schema:CreativeWork
    612 sg:pub.10.1038/nri2337 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048707274
    613 https://doi.org/10.1038/nri2337
    614 rdf:type schema:CreativeWork
    615 sg:pub.10.1038/nri2359 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032995817
    616 https://doi.org/10.1038/nri2359
    617 rdf:type schema:CreativeWork
    618 sg:pub.10.1186/gb-2002-3-6-research0027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025513631
    619 https://doi.org/10.1186/gb-2002-3-6-research0027
    620 rdf:type schema:CreativeWork
    621 https://app.dimensions.ai/details/publication/pub.1074654647 schema:CreativeWork
    622 https://doi.org/10.1002/ibd.20855 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044362423
    623 rdf:type schema:CreativeWork
    624 https://doi.org/10.1016/j.ajhg.2008.03.016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026192808
    625 rdf:type schema:CreativeWork
    626 https://doi.org/10.1016/j.ajhg.2009.08.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006057593
    627 rdf:type schema:CreativeWork
    628 https://doi.org/10.1056/nejmoa073491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017852529
    629 rdf:type schema:CreativeWork
    630 https://doi.org/10.1056/nejmoa0810440 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007392898
    631 rdf:type schema:CreativeWork
    632 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
    633 rdf:type schema:CreativeWork
    634 https://doi.org/10.1089/ars.2008.2391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059230960
    635 rdf:type schema:CreativeWork
    636 https://doi.org/10.1093/hmg/ddn288 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022365148
    637 rdf:type schema:CreativeWork
    638 https://doi.org/10.1136/gut.2008.169052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027479082
    639 rdf:type schema:CreativeWork
    640 https://doi.org/10.1194/jlr.r800033-jlr200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047556697
    641 rdf:type schema:CreativeWork
    642 https://doi.org/10.1371/journal.pone.0000691 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032680038
    643 rdf:type schema:CreativeWork
    644 https://www.grid.ac/institutes/grid.10417.33 schema:alternateName Radboud University Nijmegen Medical Centre
    645 schema:name Department of Gastroenterology and Hepatology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.
    646 rdf:type schema:Organization
    647 https://www.grid.ac/institutes/grid.10419.3d schema:alternateName Leiden University Medical Center
    648 schema:name Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands.
    649 rdf:type schema:Organization
    650 https://www.grid.ac/institutes/grid.147455.6 schema:alternateName Carnegie Mellon University
    651 schema:name Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA.
    652 rdf:type schema:Organization
    653 https://www.grid.ac/institutes/grid.163555.1 schema:alternateName Singapore General Hospital
    654 schema:name Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
    655 Laboratory of Inflammation Biology, Singapore General Hospital, Singapore.
    656 rdf:type schema:Organization
    657 https://www.grid.ac/institutes/grid.170205.1 schema:alternateName University of Chicago
    658 schema:name Department of Health Studies, University of Chicago, Chicago, Illinois, USA.
    659 rdf:type schema:Organization
    660 https://www.grid.ac/institutes/grid.17063.33 schema:alternateName University of Toronto
    661 schema:name Mount Sinai Hospital Inflammatory Bowel Disease Group, University of Toronto, Toronto, Ontario, Canada.
    662 rdf:type schema:Organization
    663 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
    664 schema:name Johns Hopkins University School of Medicine, Department of Medicine, and Johns Hopkins University Bloomberg School of Public Health, Department of Epidemiology, Baltimore, Maryland, USA.
    665 rdf:type schema:Organization
    666 https://www.grid.ac/institutes/grid.21925.3d schema:alternateName University of Pittsburgh
    667 schema:name Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, and Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
    668 rdf:type schema:Organization
    669 https://www.grid.ac/institutes/grid.24381.3c schema:alternateName Karolinska University Hospital
    670 schema:name Department for Clinical Science Intervention and Technology, Karolinska Institutet and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden.
    671 Department of Medicine, and IBD Clinical Research Group at Karolinska University Hospital, Stockholm, Sweden.
    672 Rheumatology Unit, Department of Medicine, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden.
    673 rdf:type schema:Organization
    674 https://www.grid.ac/institutes/grid.266102.1 schema:alternateName University of California, San Francisco
    675 schema:name Human Genetics, Genome Institute of Singapore, Singapore.
    676 Institute for Human Genetics, University of California San Fransisco, San Francisco, California, USA.
    677 Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.
    678 rdf:type schema:Organization
    679 https://www.grid.ac/institutes/grid.34477.33 schema:alternateName University of Washington
    680 schema:name Cardiovascular Health Research Unit, Departments of Epidemiology and General Medicine, University of Washington, Seattle, Washington, USA.
    681 rdf:type schema:Organization
    682 https://www.grid.ac/institutes/grid.410559.c schema:alternateName Centre Hospitalier de l’Université de Montréal
    683 schema:name Université de Montréal and Centre Hospitalier Universitaire de l'Université de Montréal, Montréal, Québec, Canada.
    684 rdf:type schema:Organization
    685 https://www.grid.ac/institutes/grid.411418.9 schema:alternateName Centre Hospitalier Universitaire Sainte-Justine
    686 schema:name Department of Gastroenterology, Hôpital Sainte-Justine, Montréal, Québec, Canada.
    687 rdf:type schema:Organization
    688 https://www.grid.ac/institutes/grid.412354.5 schema:alternateName Uppsala University Hospital
    689 schema:name Department of Medical Sciences, Gastroenterology Research Group, Uppsala University Hospital, Uppsala, Sweden.
    690 rdf:type schema:Organization
    691 https://www.grid.ac/institutes/grid.412367.5 schema:alternateName Örebro University Hospital
    692 schema:name Division of Gastroenterology, Department of Internal Medicine, Örebro University Hospital, Örebro, Sweden.
    693 rdf:type schema:Organization
    694 https://www.grid.ac/institutes/grid.413503.0 schema:alternateName Casa Sollievo della Sofferenza
    695 schema:name Gastroenterologia ed Endoscopia Digestiva, Ospedale 'Casa Sollievo della Sofferenza', Istituto di Ricovero e Cura a Carattere Scientifico, San Giovanni Rotondo, Italy.
    696 rdf:type schema:Organization
    697 https://www.grid.ac/institutes/grid.418377.e schema:alternateName Genome Institute of Singapore
    698 schema:name Human Genetics, Genome Institute of Singapore, Singapore.
    699 Infectious Diseases, Genome Institute of Singapore, Singapore.
    700 rdf:type schema:Organization
    701 https://www.grid.ac/institutes/grid.47100.32 schema:alternateName Yale University
    702 schema:name Department of Genetics, Yale University, New Haven, Connecticut, USA.
    703 Section of Digestive Diseases, Department of Medicine, Yale University, New Haven, Connecticut, USA.
    704 rdf:type schema:Organization
    705 https://www.grid.ac/institutes/grid.4714.6 schema:alternateName Karolinska Institute
    706 schema:name Department of Biosciences and Nutrition, Karolinska Institutet, Stockholm, Sweden.
    707 rdf:type schema:Organization
    708 https://www.grid.ac/institutes/grid.4830.f schema:alternateName University of Groningen
    709 schema:name Department of Genetics, University Medical Center Groningen and Groningen University, Groningen, The Netherlands.
    710 rdf:type schema:Organization
    711 https://www.grid.ac/institutes/grid.50956.3f schema:alternateName Cedars-Sinai Medical Center
    712 schema:name Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
    713 Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA.
    714 rdf:type schema:Organization
    715 https://www.grid.ac/institutes/grid.5650.6 schema:alternateName Academic Medical Center
    716 schema:name Department of Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, The Netherlands.
    717 rdf:type schema:Organization
    718 https://www.grid.ac/institutes/grid.63984.30 schema:alternateName McGill University Health Centre
    719 schema:name Université de Montréal and the Montreal Heart Institute, Research Center, Montréal, Québec, Canada.
    720 rdf:type schema:Organization
    721 https://www.grid.ac/institutes/grid.66859.34 schema:alternateName Broad Institute
    722 schema:name Center for Computational and Integrative Biology and Gastrointestinal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    723 Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
    724 The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
    725 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...