Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-07-24

AUTHORS

Valentina Boeva, Caroline Louis-Brennetot, Agathe Peltier, Simon Durand, Cécile Pierre-Eugène, Virginie Raynal, Heather C Etchevers, Sophie Thomas, Alban Lermine, Estelle Daudigeos-Dubus, Birgit Geoerger, Martin F Orth, Thomas G P Grünewald, Elise Diaz, Bertrand Ducos, Didier Surdez, Angel M Carcaboso, Irina Medvedeva, Thomas Deller, Valérie Combaret, Eve Lapouble, Gaelle Pierron, Sandrine Grossetête-Lalami, Sylvain Baulande, Gudrun Schleiermacher, Emmanuel Barillot, Hermann Rohrer, Olivier Delattre, Isabelle Janoueix-Lerosey

ABSTRACT

Isabelle Janoueix-Lerosey, Valentina Boeva and colleagues analyze the super-enhancer landscape of 25 neuroblastoma cell lines to define core regulatory circuits controlling gene expression programs. They find and functionally characterize two types of cell identity that contribute to the tumor heterogeneity of neuroblastoma.

PAGES

1408-1413

References to SciGraph publications

  • 2016-01-27. Active medulloblastoma enhancers reveal subgroup-specific cellular origins in NATURE
  • 2008-10. Somatic and germline activating mutations of the ALK kinase receptor in neuroblastoma in NATURE
  • 2015-06-25. Comparison of RNA-seq and microarray-based models for clinical endpoint prediction in GENOME BIOLOGY
  • 2015-11-11. Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism in NATURE
  • 2006-08-01. Lineage dependency and lineage-survival oncogenes in human cancer in NATURE REVIEWS CANCER
  • 2008-08-24. Identification of ALK as a major familial neuroblastoma predisposition gene in NATURE
  • 2016-11-10. Neuroblastoma in NATURE REVIEWS DISEASE PRIMERS
  • 2008-10. Activating mutations in ALK provide a therapeutic target in neuroblastoma in NATURE
  • 2012-09-05. An integrated encyclopedia of DNA elements in the human genome in NATURE
  • 2008-10. Oncogenic mutations of ALK kinase in neuroblastoma in NATURE
  • 2015-10-14. Telomerase activation by genomic rearrangements in high-risk neuroblastoma in NATURE
  • 2011-09-22. Primary culture of chick, mouse or human neural crest cells in NATURE PROTOCOLS
  • 1996-08. Therapeutic activity of CPT-11, a DNA-topoisomerase I inhibitor, against peripheral primitive neuroectodermal tumour and neuroblastoma xenografts in BRITISH JOURNAL OF CANCER
  • 2006-12-21. Clonogenic assay of cells in vitro in NATURE PROTOCOLS
  • 1999-05. The homeobox gene Phox2b is essential for the development of autonomic neural crest derivatives in NATURE
  • 2015-06-29. Mutational dynamics between primary and relapse neuroblastomas in NATURE GENETICS
  • 2015-11-02. TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors in NATURE GENETICS
  • 2012-03-04. Fast gapped-read alignment with Bowtie 2 in NATURE METHODS
  • Journal

    TITLE

    Nature Genetics

    ISSUE

    9

    VOLUME

    49

    Author Affiliations

  • Institut Cochin, Inserm U1016, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 8104, University Paris Descartes UMR-S1016, Paris, France
  • Institut Curie, PSL Research University, INSERM, U830, Equipe Labellisée Ligue contre le Cancer, Paris, France
  • Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France
  • Aix Marseille University, INSERM, Génétique Médicale et Génomique Fonctionnelle (GMGF) UMR S910, Marseille, France
  • INSERM U1163, Laboratory of Embryology and Genetics of Congenital Malformations, Paris Descartes - Sorbonne Paris Cité University, Imagine Institute, Paris, France
  • Assistance Publique—Hôpitaux de Paris, Paris, France
  • Gustave Roussy, Vectorology and Anticancer Therapies, UMR 8203, CNRS, Université Paris-Sud, Université Paris-Saclay, Villejuif, France
  • Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Ludwig-Maximilians-Universität München (LMU), Munich, Germany
  • LPS-ENS, Université Pierre et Marie Curie (UPMC), Université Denis Diderot, CNRS UMR 8550, PSL, Paris, France
  • Laser Microdissection Facility, Center for Interdisciplinary Research in Biology (CIRB) Collège de France, Paris, France
  • Institut de Recerca Sant Joan de Deu, Barcelona, Spain
  • Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe University Frankfurt, Frankfurt am Main, Germany
  • Centre Léon Bérard, Laboratoire de Recherche Translationnelle, Lyon, France
  • Institut Curie, Unité de Génétique Somatique, Paris, France
  • SIREDO: Care, Innovation and Research for Children, Adolescents and Young Adults with Cancer, Institut Curie, Paris, France
  • Institut Curie, Paris Sciences et Lettres (PSL) Research University, INSERM, U900, Mines-ParisTech, Paris, France
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.3921

    DOI

    http://dx.doi.org/10.1038/ng.3921

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1090882901

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28740262


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