Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2017-03

AUTHORS

Louise V Wain, Nick Shrine, María Soler Artigas, A Mesut Erzurumluoglu, Boris Noyvert, Lara Bossini-Castillo, Ma'en Obeidat, Amanda P Henry, Michael A Portelli, Robert J Hall, Charlotte K Billington, Tracy L Rimington, Anthony G Fenech, Catherine John, Tineka Blake, Victoria E Jackson, Richard J Allen, Bram P Prins, Understanding Society Scientific Group, Archie Campbell, David J Porteous, Marjo-Riitta Jarvelin, Matthias Wielscher, Alan L James, Jennie Hui, Nicholas J Wareham, Jing Hua Zhao, James F Wilson, Peter K Joshi, Beate Stubbe, Rajesh Rawal, Holger Schulz, Medea Imboden, Nicole M Probst-Hensch, Stefan Karrasch, Christian Gieger, Ian J Deary, Sarah E Harris, Jonathan Marten, Igor Rudan, Stefan Enroth, Ulf Gyllensten, Shona M Kerr, Ozren Polasek, Mika Kähönen, Ida Surakka, Veronique Vitart, Caroline Hayward, Terho Lehtimäki, Olli T Raitakari, David M Evans, A John Henderson, Craig E Pennell, Carol A Wang, Peter D Sly, Emily S Wan, Robert Busch, Brian D Hobbs, Augusto A Litonjua, David W Sparrow, Amund Gulsvik, Per S Bakke, James D Crapo, Terri H Beaty, Nadia N Hansel, Rasika A Mathias, Ingo Ruczinski, Kathleen C Barnes, Yohan Bossé, Philippe Joubert, Maarten van den Berge, Corry-Anke Brandsma, Peter D Paré, Don D Sin, David C Nickle, Ke Hao, Omri Gottesman, Frederick E Dewey, Shannon E Bruse, David J Carey, H Lester Kirchner, Geisinger-Regeneron DiscovEHR Collaboration, Stefan Jonsson, Gudmar Thorleifsson, Ingileif Jonsdottir, Thorarinn Gislason, Kari Stefansson, Claudia Schurmann, Girish Nadkarni, Erwin P Bottinger, Ruth J F Loos, Robin G Walters, Zhengming Chen, Iona Y Millwood, Julien Vaucher, Om P Kurmi, Liming Li, Anna L Hansell, Chris Brightling, Eleftheria Zeggini, Michael H Cho, Edwin K Silverman, Ian Sayers, Gosia Trynka, Andrew P Morris, David P Strachan, Ian P Hall, Martin D Tobin

ABSTRACT

Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals, selected from extremes of the lung function distribution in UK Biobank, and follow-up in 95,375 individuals, we increased the yield of independent signals for lung function from 54 to 97. A genetic risk score was associated with COPD susceptibility (odds ratio per 1 s.d. of the risk score (∼6 alleles) (95% confidence interval) = 1.24 (1.20-1.27), P = 5.05 × 10-49), and we observed a 3.7-fold difference in COPD risk between individuals in the highest and lowest genetic risk score deciles in UK Biobank. The 97 signals show enrichment in genes for development, elastic fibers and epigenetic regulation pathways. We highlight targets for drugs and compounds in development for COPD and asthma (genes in the inositol phosphate metabolism pathway and CHRM3) and describe targets for potential drug repositioning from other clinical indications. More... »

PAGES

416-425

References to SciGraph publications

  • 2015-10. The UK10K project identifies rare variants in health and disease in NATURE
  • 2015-05. Large-scale whole-genome sequencing of the Icelandic population in NATURE GENETICS
  • 2015-08. The support of human genetic evidence for approved drug indications in NATURE GENETICS
  • 1987-10. HLA-DQβ gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus in NATURE
  • 2010-01. Genome-wide association study identifies five loci associated with lung function in NATURE GENETICS
  • 2012-04. Use of genome-wide association studies for drug repositioning in NATURE BIOTECHNOLOGY
  • 2011-11. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function in NATURE GENETICS
  • 2010-01. Lung function and airway diseases in NATURE GENETICS
  • 2013-10. Systematic identification of trans eQTLs as putative drivers of known disease associations in NATURE GENETICS
  • 2015-12. Accelerated extracellular matrix turnover during exacerbations of COPD in RESPIRATORY RESEARCH
  • 2010-03. Variants in FAM13A are associated with chronic obstructive pulmonary disease in NATURE GENETICS
  • 2016-08. The (in)famous GWAS P-value threshold revisited and updated for low-frequency variants in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2015-12. Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel in NATURE COMMUNICATIONS
  • 2014-07. Genome-wide association analysis identifies six new loci associated with forced vital capacity in NATURE GENETICS
  • 2012-04. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits in NATURE GENETICS
  • 2010-10-28. A map of human genome variation from population-scale sequencing in NATURE
  • 2015-12. Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation in NATURE COMMUNICATIONS
  • 2015-02. Integrative analysis of 111 reference human epigenomes in NATURE
  • 2010-01. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function in NATURE GENETICS
  • 2017-03. Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis in NATURE GENETICS
  • Journal

    TITLE

    Nature Genetics

    ISSUE

    3

    VOLUME

    49

    Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.3787

    DOI

    http://dx.doi.org/10.1038/ng.3787

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1083686808

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/28166213


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