Ontology type: schema:ScholarlyArticle Open Access: True
2016-04
AUTHORSHikmat A Al-Ahmadie, Gopa Iyer, Byron H Lee, Sasinya N Scott, Rohit Mehra, Aditya Bagrodia, Emmet J Jordan, Sizhi Paul Gao, Ricardo Ramirez, Eugene K Cha, Neil B Desai, Emily C Zabor, Irina Ostrovnaya, Anuradha Gopalan, Ying-Bei Chen, Samson W Fine, Satish K Tickoo, Anupama Gandhi, Joseph Hreiki, Agnès Viale, Maria E Arcila, Guido Dalbagni, Jonathan E Rosenberg, Bernard H Bochner, Dean F Bajorin, Michael F Berger, Victor E Reuter, Barry S Taylor, David B Solit
ABSTRACTPlasmacytoid bladder cancer is an aggressive histologic variant with a high risk of disease-specific mortality. Using whole-exome and targeted sequencing, we find that truncating somatic alterations in the CDH1 gene occur in 84% of plasmacytoid carcinomas and are specific to this histologic variant. Consistent with the aggressive clinical behavior of plasmacytoid carcinomas, which frequently recur locally, CRISPR/Cas9-mediated knockout of CDH1 in bladder cancer cells enhanced cell migration. More... »
PAGES356-358
http://scigraph.springernature.com/pub.10.1038/ng.3503
DOIhttp://dx.doi.org/10.1038/ng.3503
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1042274387
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/26901067
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JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.3503'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.3503'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.3503'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.3503'
This table displays all metadata directly associated to this object as RDF triples.
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20 BLANK NODES