Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

2009-05-03

AUTHORS

Lajos Mátés, Marinee K L Chuah, Eyayu Belay, Boris Jerchow, Namitha Manoj, Abel Acosta-Sanchez, Dawid P Grzela, Andrea Schmitt, Katja Becker, Janka Matrai, Ling Ma, Ermira Samara-Kuko, Conny Gysemans, Diana Pryputniewicz, Csaba Miskey, Bradley Fletcher, Thierry VandenDriessche, Zoltán Ivics, Zsuzsanna Izsvák

ABSTRACT

Zsuzsanna Izsvák and colleagues report the generation of a hyperactive version of the Sleeping Beauty transposase that supports efficient and stable gene transfer into human CD34+ cells enriched for hematopoietic stem or progenitor cells.

PAGES

753-761

Journal

TITLE

Nature Genetics

ISSUE

6

VOLUME

41

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  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.343

    DOI

    http://dx.doi.org/10.1038/ng.343

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1034767313

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/19412179


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