Population genetic differentiation of height and body mass index across Europe View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2015-11

AUTHORS

Matthew R Robinson, Gibran Hemani, Carolina Medina-Gomez, Massimo Mezzavilla, Tonu Esko, Konstantin Shakhbazov, Joseph E Powell, Anna Vinkhuyzen, Sonja I Berndt, Stefan Gustafsson, Anne E Justice, Bratati Kahali, Adam E Locke, Tune H Pers, Sailaja Vedantam, Andrew R Wood, Wouter van Rheenen, Ole A Andreassen, Paolo Gasparini, Andres Metspalu, Leonard H van den Berg, Jan H Veldink, Fernando Rivadeneira, Thomas M Werge, Goncalo R Abecasis, Dorret I Boomsma, Daniel I Chasman, Eco J C de Geus, Timothy M Frayling, Joel N Hirschhorn, Jouke Jan Hottenga, Erik Ingelsson, Ruth J F Loos, Patrik K E Magnusson, Nicholas G Martin, Grant W Montgomery, Kari E North, Nancy L Pedersen, Timothy D Spector, Elizabeth K Speliotes, Michael E Goddard, Jian Yang, Peter M Visscher

ABSTRACT

Across-nation differences in the mean values for complex traits are common, but the reasons for these differences are unknown. Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries. Using discovery data on over 250,000 individuals and unbiased effect size estimates from 17,500 sibling pairs, we estimate that 24% (95% credible interval (CI) = 9%, 41%) and 8% (95% CI = 4%, 16%) of the captured additive genetic variance for height and BMI, respectively, reflect population genetic differences. Population genetic divergence differed significantly from that in a null model (height, P < 3.94 × 10(-8); BMI, P < 5.95 × 10(-4)), and we find an among-population genetic correlation for tall and slender individuals (r = -0.80, 95% CI = -0.95, -0.60), consistent with correlated selection for both phenotypes. Observed differences in height among populations reflected the predicted genetic means (r = 0.51; P < 0.001), but environmental differences across Europe masked genetic differentiation for BMI (P < 0.58). More... »

PAGES

1357-1362

References to SciGraph publications

  • 2008-03. Natural selection has driven population differentiation in modern humans in NATURE GENETICS
  • 2013-03. QST–FST comparisons: evolutionary and ecological insights from genomic heterogeneity in NATURE REVIEWS GENETICS
  • 2014-11. Defining the role of common variation in the genomic and biological architecture of adult human height in NATURE GENETICS
  • 2007-10-18. Genome-wide detection and characterization of positive selection in human populations in NATURE
  • 2012-02. A linear complexity phasing method for thousands of genomes in NATURE METHODS
  • 2007-11. Recent and ongoing selection in the human genome in NATURE REVIEWS GENETICS
  • 2013-06. Genetic characterization of northeastern Italian population isolates in the context of broader European genetic diversity in EUROPEAN JOURNAL OF HUMAN GENETICS
  • 2012-11. An integrated map of genetic variation from 1,092 human genomes in NATURE
  • 2010-07. Common SNPs explain a large proportion of the heritability for human height in NATURE GENETICS
  • 2012-09. Evidence of widespread selection on standing variation in Europe at height-associated SNPs in NATURE GENETICS
  • 2012-09. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes in NATURE GENETICS
  • 2012-04. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits in NATURE GENETICS
  • 2010-01. From evolutionary genetics to human immunology: how selection shapes host defence genes in NATURE REVIEWS GENETICS
  • 2010-11. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index in NATURE GENETICS
  • 2005-10. Natural selection on protein-coding genes in the human genome in NATURE
  • 2012-10. FTO genotype is associated with phenotypic variability of body mass index in NATURE
  • 2010-10. Hundreds of variants clustered in genomic loci and biological pathways affect human height in NATURE
  • 2015-02. Genetic studies of body mass index yield new insights for obesity biology in NATURE
  • 2010-09. Sporadic cases are the norm for complex disease in EUROPEAN JOURNAL OF HUMAN GENETICS
  • Identifiers

    URI

    http://scigraph.springernature.com/pub.10.1038/ng.3401

    DOI

    http://dx.doi.org/10.1038/ng.3401

    DIMENSIONS

    https://app.dimensions.ai/details/publication/pub.1032008843

    PUBMED

    https://www.ncbi.nlm.nih.gov/pubmed/26366552


    Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
    Incoming Citations Browse incoming citations for this publication using opencitations.net

    JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Genetics", 
            "type": "DefinedTerm"
          }, 
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "name": "Biological Sciences", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Algorithms", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Body Height", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Body Mass Index", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Europe", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene Expression Profiling", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Gene-Environment Interaction", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetic Variation", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genetics, Population", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genome-Wide Association Study", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Genotype", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Geography", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Humans", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Models, Genetic", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Phenotype", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Polymorphism, Single Nucleotide", 
            "type": "DefinedTerm"
          }, 
          {
            "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
            "name": "Principal Component Analysis", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Robinson", 
            "givenName": "Matthew R", 
            "id": "sg:person.0726250204.50", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726250204.50"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hemani", 
            "givenName": "Gibran", 
            "id": "sg:person.011234570267.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011234570267.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Medina-Gomez", 
            "givenName": "Carolina", 
            "id": "sg:person.0765006250.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765006250.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Sanger Institute", 
              "id": "https://www.grid.ac/institutes/grid.10306.34", 
              "name": [
                "Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy.", 
                "Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Mezzavilla", 
            "givenName": "Massimo", 
            "id": "sg:person.0642753276.96", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642753276.96"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harvard University", 
              "id": "https://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Estonian Genome Center, University of Tartu, Tartu, Estonia.", 
                "Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.", 
                "Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.", 
                "Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Esko", 
            "givenName": "Tonu", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Shakhbazov", 
            "givenName": "Konstantin", 
            "id": "sg:person.01065017530.29", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065017530.29"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.", 
                "University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Powell", 
            "givenName": "Joseph E", 
            "id": "sg:person.01246530370.86", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246530370.86"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vinkhuyzen", 
            "givenName": "Anna", 
            "id": "sg:person.01071450175.91", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071450175.91"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "National Institutes of Health", 
              "id": "https://www.grid.ac/institutes/grid.94365.3d", 
              "name": [
                "Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Berndt", 
            "givenName": "Sonja I", 
            "id": "sg:person.016176207377.25", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016176207377.25"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Uppsala University", 
              "id": "https://www.grid.ac/institutes/grid.8993.b", 
              "name": [
                "Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gustafsson", 
            "givenName": "Stefan", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of North Carolina at Chapel Hill", 
              "id": "https://www.grid.ac/institutes/grid.10698.36", 
              "name": [
                "Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Justice", 
            "givenName": "Anne E", 
            "id": "sg:person.01255157234.57", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255157234.57"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.", 
                "Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Kahali", 
            "givenName": "Bratati", 
            "id": "sg:person.01110401434.52", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110401434.52"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Locke", 
            "givenName": "Adam E", 
            "id": "sg:person.0756367034.05", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756367034.05"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Technical University of Denmark", 
              "id": "https://www.grid.ac/institutes/grid.5170.3", 
              "name": [
                "Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.", 
                "Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.", 
                "Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.", 
                "Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pers", 
            "givenName": "Tune H", 
            "id": "sg:person.01134046226.44", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134046226.44"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Broad Institute", 
              "id": "https://www.grid.ac/institutes/grid.66859.34", 
              "name": [
                "Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.", 
                "Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Vedantam", 
            "givenName": "Sailaja", 
            "id": "sg:person.01163250252.90", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163250252.90"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Exeter", 
              "id": "https://www.grid.ac/institutes/grid.8391.3", 
              "name": [
                "Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Wood", 
            "givenName": "Andrew R", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Utrecht", 
              "id": "https://www.grid.ac/institutes/grid.7692.a", 
              "name": [
                "Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "van Rheenen", 
            "givenName": "Wouter", 
            "id": "sg:person.01167052663.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167052663.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "name": [
                "Norwegian Centre for Mental Disorders Research (NORMENT), KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Andreassen", 
            "givenName": "Ole A", 
            "id": "sg:person.01263457230.91", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263457230.91"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Sanger Institute", 
              "id": "https://www.grid.ac/institutes/grid.10306.34", 
              "name": [
                "Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy.", 
                "Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Gasparini", 
            "givenName": "Paolo", 
            "id": "sg:person.01300757630.84", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300757630.84"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Tartu", 
              "id": "https://www.grid.ac/institutes/grid.10939.32", 
              "name": [
                "Estonian Genome Center, University of Tartu, Tartu, Estonia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Metspalu", 
            "givenName": "Andres", 
            "id": "sg:person.01313145634.66", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313145634.66"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Utrecht", 
              "id": "https://www.grid.ac/institutes/grid.7692.a", 
              "name": [
                "Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "van den Berg", 
            "givenName": "Leonard H", 
            "id": "sg:person.0700316214.32", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700316214.32"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University Medical Center Utrecht", 
              "id": "https://www.grid.ac/institutes/grid.7692.a", 
              "name": [
                "Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Veldink", 
            "givenName": "Jan H", 
            "id": "sg:person.01114462237.40", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114462237.40"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Erasmus University Medical Center", 
              "id": "https://www.grid.ac/institutes/grid.5645.2", 
              "name": [
                "Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Rivadeneira", 
            "givenName": "Fernando", 
            "id": "sg:person.01006410206.09", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006410206.09"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Lundbeck Foundation", 
              "id": "https://www.grid.ac/institutes/grid.452548.a", 
              "name": [
                "Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Devices Copenhagen, Roskilde, Denmark.", 
                "Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.", 
                "Lundbeck Foundation Initiative for Integrative Psychiatric Research, (iPSYCH), Aarhus, Denmark."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Werge", 
            "givenName": "Thomas M", 
            "id": "sg:person.01223240773.33", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223240773.33"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Abecasis", 
            "givenName": "Goncalo R", 
            "id": "sg:person.0641525362.39", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641525362.39"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VU University Amsterdam", 
              "id": "https://www.grid.ac/institutes/grid.12380.38", 
              "name": [
                "Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.", 
                "EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.", 
                "Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Boomsma", 
            "givenName": "Dorret I", 
            "id": "sg:person.0610667722.81", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610667722.81"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Brigham and Women's Hospital", 
              "id": "https://www.grid.ac/institutes/grid.62560.37", 
              "name": [
                "Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.", 
                "Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Chasman", 
            "givenName": "Daniel I", 
            "id": "sg:person.0760704165.88", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760704165.88"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VU University Amsterdam", 
              "id": "https://www.grid.ac/institutes/grid.12380.38", 
              "name": [
                "Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.", 
                "EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.", 
                "Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "de Geus", 
            "givenName": "Eco J C", 
            "id": "sg:person.015224655437.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015224655437.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Exeter", 
              "id": "https://www.grid.ac/institutes/grid.8391.3", 
              "name": [
                "Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Frayling", 
            "givenName": "Timothy M", 
            "id": "sg:person.012766272254.47", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012766272254.47"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Harvard University", 
              "id": "https://www.grid.ac/institutes/grid.38142.3c", 
              "name": [
                "Estonian Genome Center, University of Tartu, Tartu, Estonia.", 
                "Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.", 
                "Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.", 
                "Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hirschhorn", 
            "givenName": "Joel N", 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "VU University Amsterdam", 
              "id": "https://www.grid.ac/institutes/grid.12380.38", 
              "name": [
                "Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.", 
                "EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.", 
                "Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Hottenga", 
            "givenName": "Jouke Jan", 
            "id": "sg:person.0610570026.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610570026.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Wellcome Centre for Human Genetics", 
              "id": "https://www.grid.ac/institutes/grid.270683.8", 
              "name": [
                "Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.", 
                "Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Ingelsson", 
            "givenName": "Erik", 
            "id": "sg:person.01145654113.82", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145654113.82"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Icahn School of Medicine at Mount Sinai", 
              "id": "https://www.grid.ac/institutes/grid.59734.3c", 
              "name": [
                "Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.", 
                "Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.", 
                "Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.", 
                "Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Loos", 
            "givenName": "Ruth J F", 
            "id": "sg:person.012266613364.42", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012266613364.42"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska Institute", 
              "id": "https://www.grid.ac/institutes/grid.4714.6", 
              "name": [
                "Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Magnusson", 
            "givenName": "Patrik K E", 
            "id": "sg:person.015576406233.51", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015576406233.51"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "QIMR Berghofer Medical Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.1049.c", 
              "name": [
                "QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Martin", 
            "givenName": "Nicholas G", 
            "id": "sg:person.010700366647.17", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700366647.17"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "QIMR Berghofer Medical Research Institute", 
              "id": "https://www.grid.ac/institutes/grid.1049.c", 
              "name": [
                "QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Montgomery", 
            "givenName": "Grant W", 
            "id": "sg:person.01117721120.30", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117721120.30"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of North Carolina at Chapel Hill", 
              "id": "https://www.grid.ac/institutes/grid.10698.36", 
              "name": [
                "Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.", 
                "Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.", 
                "Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "North", 
            "givenName": "Kari E", 
            "id": "sg:person.011405001662.87", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011405001662.87"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "Karolinska Institute", 
              "id": "https://www.grid.ac/institutes/grid.4714.6", 
              "name": [
                "Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Pedersen", 
            "givenName": "Nancy L", 
            "id": "sg:person.0750524661.10", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750524661.10"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "King's College London", 
              "id": "https://www.grid.ac/institutes/grid.13097.3c", 
              "name": [
                "Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, UK."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Spector", 
            "givenName": "Timothy D", 
            "id": "sg:person.012631765612.56", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631765612.56"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Michigan\u2013Ann Arbor", 
              "id": "https://www.grid.ac/institutes/grid.214458.e", 
              "name": [
                "Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Speliotes", 
            "givenName": "Elizabeth K", 
            "id": "sg:person.01201362637.02", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201362637.02"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Melbourne", 
              "id": "https://www.grid.ac/institutes/grid.1008.9", 
              "name": [
                "Biosciences Research Division, Department of Primary Industries, Melbourne, Victoria, Australia.", 
                "Department of Food and Agricultural Systems, University of Melbourne, Melbourne, Victoria, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Goddard", 
            "givenName": "Michael E", 
            "id": "sg:person.0623730357.31", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623730357.31"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.", 
                "University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Yang", 
            "givenName": "Jian", 
            "id": "sg:person.0730724336.65", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730724336.65"
            ], 
            "type": "Person"
          }, 
          {
            "affiliation": {
              "alternateName": "University of Queensland", 
              "id": "https://www.grid.ac/institutes/grid.1003.2", 
              "name": [
                "Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.", 
                "University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia."
              ], 
              "type": "Organization"
            }, 
            "familyName": "Visscher", 
            "givenName": "Peter M", 
            "id": "sg:person.01033044533.08", 
            "sameAs": [
              "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033044533.08"
            ], 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "sg:pub.10.1038/nature11632", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000661742", 
              "https://doi.org/10.1038/nature11632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001355162", 
              "https://doi.org/10.1038/nrg2698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001355162", 
              "https://doi.org/10.1038/nrg2698"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/evo.12268", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001568892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg2187", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002543859", 
              "https://doi.org/10.1038/nrg2187"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nmeth.1785", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002640757", 
              "https://doi.org/10.1038/nmeth.1785"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ejhg.2009.177", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003075684", 
              "https://doi.org/10.1038/ejhg.2009.177"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1004412", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004866588"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ajpa.20107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004938254"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(07)61696-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005365609"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2213", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006110604", 
              "https://doi.org/10.1038/ng.2213"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.3097", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006357119", 
              "https://doi.org/10.1038/ng.3097"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/dds491", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006408755"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(06)68770-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006956756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(14)60460-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007350540"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cub.2008.04.074", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009456892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2368", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010777696", 
              "https://doi.org/10.1038/ng.2368"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.2383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011024359", 
              "https://doi.org/10.1038/ng.2383"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/strokeaha.111.000067", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012257344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/strokeaha.111.000067", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012257344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.genet.36.050802.093940", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012760112"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.686", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013643799", 
              "https://doi.org/10.1038/ng.686"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.686", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013643799", 
              "https://doi.org/10.1038/ng.686"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.608", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015057090", 
              "https://doi.org/10.1038/ng.608"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.608", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015057090", 
              "https://doi.org/10.1038/ng.608"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/519795", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019061180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1003355", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019838558"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng.78", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020863803", 
              "https://doi.org/10.1038/ng.78"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0049837", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021842939"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(10)62037-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021970749"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nrg3395", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022150201", 
              "https://doi.org/10.1038/nrg3395"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0906182107", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022731697"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1003348", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023968606"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature11401", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024448471", 
              "https://doi.org/10.1038/nature11401"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ajhg.2012.06.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024911758"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(11)60814-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025087671"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(12)61719-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025534845"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1474-4422(09)70023-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028300612"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ejhg.2012.229", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030585304", 
              "https://doi.org/10.1038/ejhg.2012.229"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0027588", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032264196"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/eva.12045", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035837962"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature06250", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036876479", 
              "https://doi.org/10.1038/nature06250"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/g3.111.001198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037455212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/g3.111.001198", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037455212"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09410", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037714920", 
              "https://doi.org/10.1038/nature09410"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature09410", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037714920", 
              "https://doi.org/10.1038/nature09410"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pgen.1000008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037949611"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1161/circulationaha.111.018820", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039416458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/genetics.111.129387", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040195285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/genetics.111.129387", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040195285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/1055-9965.epi-10-0437", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040210484"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04240", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041792930", 
              "https://doi.org/10.1038/nature04240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature04240", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041792930", 
              "https://doi.org/10.1038/nature04240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pbio.0020286", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044097460"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tig.2014.02.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044265637"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1001/jama.282.7.677", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047685348"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/genetics.112.144758", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050687048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1534/genetics.112.144758", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050687048"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2337/diacare.27.5.1047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051349743"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0910803106", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051439634"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.84.23.8512", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051608823"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/20780389.2012.657489", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051662195"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cub.2009.11.055", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051673317"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature14177", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053003561", 
              "https://doi.org/10.1038/nature14177"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(07)61415-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053711949"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/283642", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058593765"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/302698", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058610264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.hjr.0000114707.27531.48", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060329945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.hjr.0000114707.27531.48", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060329945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.hjr.0000114707.27531.48", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060329945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1227001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062467000"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.18637/jss.v033.i02", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068672497"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2307/2408641", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069917637"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/ajcn/84.1.289", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077281125"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2015-11", 
        "datePublishedReg": "2015-11-01", 
        "description": "Across-nation differences in the mean values for complex traits are common, but the reasons for these differences are unknown. Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries. Using discovery data on over 250,000 individuals and unbiased effect size estimates from 17,500 sibling pairs, we estimate that 24% (95% credible interval (CI) = 9%, 41%) and 8% (95% CI = 4%, 16%) of the captured additive genetic variance for height and BMI, respectively, reflect population genetic differences. Population genetic divergence differed significantly from that in a null model (height, P < 3.94 \u00d7 10(-8); BMI, P < 5.95 \u00d7 10(-4)), and we find an among-population genetic correlation for tall and slender individuals (r = -0.80, 95% CI = -0.95, -0.60), consistent with correlated selection for both phenotypes. Observed differences in height among populations reflected the predicted genetic means (r = 0.51; P < 0.001), but environmental differences across Europe masked genetic differentiation for BMI (P < 0.58). ", 
        "genre": "research_article", 
        "id": "sg:pub.10.1038/ng.3401", 
        "inLanguage": [
          "en"
        ], 
        "isAccessibleForFree": true, 
        "isFundedItemOf": [
          {
            "id": "sg:grant.4128757", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6736295", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2669481", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3754454", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6721191", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3773756", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2526608", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2684560", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4700131", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2669474", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3560505", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2484886", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3567755", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2690128", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2758966", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6736244", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.3560622", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2443777", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2696437", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.6736536", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2686930", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2443780", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2443778", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4118013", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4113448", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.2443909", 
            "type": "MonetaryGrant"
          }, 
          {
            "id": "sg:grant.4137736", 
            "type": "MonetaryGrant"
          }
        ], 
        "isPartOf": [
          {
            "id": "sg:journal.1103138", 
            "issn": [
              "1061-4036", 
              "1546-1718"
            ], 
            "name": "Nature Genetics", 
            "type": "Periodical"
          }, 
          {
            "issueNumber": "11", 
            "type": "PublicationIssue"
          }, 
          {
            "type": "PublicationVolume", 
            "volumeNumber": "47"
          }
        ], 
        "name": "Population genetic differentiation of height and body mass index across Europe", 
        "pagination": "1357-1362", 
        "productId": [
          {
            "name": "readcube_id", 
            "type": "PropertyValue", 
            "value": [
              "987bef015e75cf4dc30c24db63c99b9853504a60ff48f21ddd2c0e033f912b9b"
            ]
          }, 
          {
            "name": "pubmed_id", 
            "type": "PropertyValue", 
            "value": [
              "26366552"
            ]
          }, 
          {
            "name": "nlm_unique_id", 
            "type": "PropertyValue", 
            "value": [
              "9216904"
            ]
          }, 
          {
            "name": "doi", 
            "type": "PropertyValue", 
            "value": [
              "10.1038/ng.3401"
            ]
          }, 
          {
            "name": "dimensions_id", 
            "type": "PropertyValue", 
            "value": [
              "pub.1032008843"
            ]
          }
        ], 
        "sameAs": [
          "https://doi.org/10.1038/ng.3401", 
          "https://app.dimensions.ai/details/publication/pub.1032008843"
        ], 
        "sdDataset": "articles", 
        "sdDatePublished": "2019-04-10T19:45", 
        "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
        "sdPublisher": {
          "name": "Springer Nature - SN SciGraph project", 
          "type": "Organization"
        }, 
        "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8681_00000425.jsonl", 
        "type": "ScholarlyArticle", 
        "url": "http://www.nature.com/articles/ng.3401"
      }
    ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.3401'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.3401'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.3401'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.3401'


     

    This table displays all metadata directly associated to this object as RDF triples.

    774 TRIPLES      21 PREDICATES      108 URIs      37 LITERALS      25 BLANK NODES

    Subject Predicate Object
    1 sg:pub.10.1038/ng.3401 schema:about N0cb0f7a0a0454e15ac3db6de60c28cfe
    2 N14d97642f7cb4edba99ff2a3b99901e0
    3 N29f15bd4917a4781ae38576094dc0092
    4 N44ccfaef3dfe4dbfbac6a4838b6d0fe0
    5 N45e981877570471f96d4f6e1e865ff9c
    6 N64f31919e7514976907b522ca07caa27
    7 N7d5c0185c4474141ab8976cf3f734558
    8 N8a78164aba214d3782ae204c5d018a8d
    9 N9818ec6b2a0e4841bc85eeb7665ce1c8
    10 Nb007060a6ff2455fa864f2f9de4c1185
    11 Nb38a825f365549488482bff55cacabe7
    12 Nbbe6438d59c74eb3bea5f6dc25a9c91e
    13 Ncb2b6e02b8194287b5e5d6994a0c4350
    14 Ncc68026a1efa433f8b18717c04d3afd9
    15 Nd17dcba378b540378b6e2ed290d93501
    16 Nf56a6c9b1bf44ad5a9307de8af061e70
    17 anzsrc-for:06
    18 anzsrc-for:0604
    19 schema:author N4bcecadc570845f9bd0481021297c424
    20 schema:citation sg:pub.10.1038/ejhg.2009.177
    21 sg:pub.10.1038/ejhg.2012.229
    22 sg:pub.10.1038/nature04240
    23 sg:pub.10.1038/nature06250
    24 sg:pub.10.1038/nature09410
    25 sg:pub.10.1038/nature11401
    26 sg:pub.10.1038/nature11632
    27 sg:pub.10.1038/nature14177
    28 sg:pub.10.1038/ng.2213
    29 sg:pub.10.1038/ng.2368
    30 sg:pub.10.1038/ng.2383
    31 sg:pub.10.1038/ng.3097
    32 sg:pub.10.1038/ng.608
    33 sg:pub.10.1038/ng.686
    34 sg:pub.10.1038/ng.78
    35 sg:pub.10.1038/nmeth.1785
    36 sg:pub.10.1038/nrg2187
    37 sg:pub.10.1038/nrg2698
    38 sg:pub.10.1038/nrg3395
    39 https://doi.org/10.1001/jama.282.7.677
    40 https://doi.org/10.1002/ajpa.20107
    41 https://doi.org/10.1016/j.ajhg.2012.06.013
    42 https://doi.org/10.1016/j.cub.2008.04.074
    43 https://doi.org/10.1016/j.cub.2009.11.055
    44 https://doi.org/10.1016/j.tig.2014.02.003
    45 https://doi.org/10.1016/s0140-6736(06)68770-9
    46 https://doi.org/10.1016/s0140-6736(07)61415-9
    47 https://doi.org/10.1016/s0140-6736(07)61696-1
    48 https://doi.org/10.1016/s0140-6736(10)62037-5
    49 https://doi.org/10.1016/s0140-6736(11)60814-3
    50 https://doi.org/10.1016/s0140-6736(12)61719-x
    51 https://doi.org/10.1016/s0140-6736(14)60460-8
    52 https://doi.org/10.1016/s1474-4422(09)70023-7
    53 https://doi.org/10.1073/pnas.0906182107
    54 https://doi.org/10.1073/pnas.0910803106
    55 https://doi.org/10.1073/pnas.84.23.8512
    56 https://doi.org/10.1080/20780389.2012.657489
    57 https://doi.org/10.1086/283642
    58 https://doi.org/10.1086/302698
    59 https://doi.org/10.1086/519795
    60 https://doi.org/10.1093/ajcn/84.1.289
    61 https://doi.org/10.1093/hmg/dds491
    62 https://doi.org/10.1097/01.hjr.0000114707.27531.48
    63 https://doi.org/10.1111/eva.12045
    64 https://doi.org/10.1111/evo.12268
    65 https://doi.org/10.1126/science.1227001
    66 https://doi.org/10.1146/annurev.genet.36.050802.093940
    67 https://doi.org/10.1158/1055-9965.epi-10-0437
    68 https://doi.org/10.1161/circulationaha.111.018820
    69 https://doi.org/10.1161/strokeaha.111.000067
    70 https://doi.org/10.1371/journal.pbio.0020286
    71 https://doi.org/10.1371/journal.pgen.1000008
    72 https://doi.org/10.1371/journal.pgen.1003348
    73 https://doi.org/10.1371/journal.pgen.1003355
    74 https://doi.org/10.1371/journal.pgen.1004412
    75 https://doi.org/10.1371/journal.pone.0027588
    76 https://doi.org/10.1371/journal.pone.0049837
    77 https://doi.org/10.1534/g3.111.001198
    78 https://doi.org/10.1534/genetics.111.129387
    79 https://doi.org/10.1534/genetics.112.144758
    80 https://doi.org/10.18637/jss.v033.i02
    81 https://doi.org/10.2307/2408641
    82 https://doi.org/10.2337/diacare.27.5.1047
    83 schema:datePublished 2015-11
    84 schema:datePublishedReg 2015-11-01
    85 schema:description Across-nation differences in the mean values for complex traits are common, but the reasons for these differences are unknown. Here we find that many independent loci contribute to population genetic differences in height and body mass index (BMI) in 9,416 individuals across 14 European countries. Using discovery data on over 250,000 individuals and unbiased effect size estimates from 17,500 sibling pairs, we estimate that 24% (95% credible interval (CI) = 9%, 41%) and 8% (95% CI = 4%, 16%) of the captured additive genetic variance for height and BMI, respectively, reflect population genetic differences. Population genetic divergence differed significantly from that in a null model (height, P < 3.94 × 10(-8); BMI, P < 5.95 × 10(-4)), and we find an among-population genetic correlation for tall and slender individuals (r = -0.80, 95% CI = -0.95, -0.60), consistent with correlated selection for both phenotypes. Observed differences in height among populations reflected the predicted genetic means (r = 0.51; P < 0.001), but environmental differences across Europe masked genetic differentiation for BMI (P < 0.58).
    86 schema:genre research_article
    87 schema:inLanguage en
    88 schema:isAccessibleForFree true
    89 schema:isPartOf N03c77b696cfb4a46bb6a8d8053e6a193
    90 N8ae87c61ff3e4ea8b36bbfc7d5c52ab7
    91 sg:journal.1103138
    92 schema:name Population genetic differentiation of height and body mass index across Europe
    93 schema:pagination 1357-1362
    94 schema:productId N164e328a31f04c8991ec294b357aa341
    95 N47290c2b11a146958853f5e28e54c570
    96 N4a7852a8377c443aa8514646311dfc83
    97 N509bf2d44d554285bf8812efc3998651
    98 Nd72c0198309740f98fe245d9c25d60b2
    99 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032008843
    100 https://doi.org/10.1038/ng.3401
    101 schema:sdDatePublished 2019-04-10T19:45
    102 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    103 schema:sdPublisher N80c7ac2e67e146e2adb8dab1644296dc
    104 schema:url http://www.nature.com/articles/ng.3401
    105 sgo:license sg:explorer/license/
    106 sgo:sdDataset articles
    107 rdf:type schema:ScholarlyArticle
    108 N03c77b696cfb4a46bb6a8d8053e6a193 schema:volumeNumber 47
    109 rdf:type schema:PublicationVolume
    110 N07cc6806a3e94d5895bab3cf9b9bb319 rdf:first sg:person.01071450175.91
    111 rdf:rest N1f866fc438b642e6b5db7af69ff9472f
    112 N0b9162dfdd8b45d784fc7c28a973a2bd rdf:first sg:person.01145654113.82
    113 rdf:rest N4a82691e85d64d399aca28661934b922
    114 N0cb0f7a0a0454e15ac3db6de60c28cfe schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    115 schema:name Models, Genetic
    116 rdf:type schema:DefinedTerm
    117 N0e2c586c49eb4adcb48b987043c9b0fc rdf:first sg:person.01163250252.90
    118 rdf:rest N95618f48cf8b4ad1af033317071c3964
    119 N122df65b53dc4655b2be333fb36fd205 rdf:first N87afbf03ee5d419ab3f6eaf127c9b91b
    120 rdf:rest N96888a240a954d78a46e092cbd820916
    121 N14d97642f7cb4edba99ff2a3b99901e0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    122 schema:name Phenotype
    123 rdf:type schema:DefinedTerm
    124 N164e328a31f04c8991ec294b357aa341 schema:name readcube_id
    125 schema:value 987bef015e75cf4dc30c24db63c99b9853504a60ff48f21ddd2c0e033f912b9b
    126 rdf:type schema:PropertyValue
    127 N165c77c0779a45c59d3d4722a0c5f1ad rdf:first sg:person.01065017530.29
    128 rdf:rest N70b30f46753b4682a517b7bad8861a26
    129 N1e673f6cd6154542ad437506881ad645 rdf:first sg:person.01263457230.91
    130 rdf:rest Nb3ea383cfd814d24a71d6fc765501395
    131 N1f866fc438b642e6b5db7af69ff9472f rdf:first sg:person.016176207377.25
    132 rdf:rest Ndd5c3b7795c947749ed96150a14c7b5a
    133 N24095df2c4ba44fdbd160e38960efa10 rdf:first sg:person.0623730357.31
    134 rdf:rest Neb8c40317f1d4b71bbb40793645198fa
    135 N24a9013edb024e598096d2c894bc0623 rdf:first sg:person.012631765612.56
    136 rdf:rest N894f13fc121643659b74b8ecda66b084
    137 N29f15bd4917a4781ae38576094dc0092 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    138 schema:name Humans
    139 rdf:type schema:DefinedTerm
    140 N2f670c9106454191990eb9b617526601 schema:name Norwegian Centre for Mental Disorders Research (NORMENT), KG Jebsen Centre for Psychosis Research, Division of Mental Health and Addiction, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
    141 rdf:type schema:Organization
    142 N2fe973439c614c52925a64444b328585 rdf:first sg:person.0700316214.32
    143 rdf:rest Nc75ecfa8f01644ebac0465965432177b
    144 N3c36893a8a404f1ea35699e59762043c rdf:first sg:person.011234570267.86
    145 rdf:rest Nb3e4e352d9f84e6b8d63f74464331b2a
    146 N44ccfaef3dfe4dbfbac6a4838b6d0fe0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    147 schema:name Europe
    148 rdf:type schema:DefinedTerm
    149 N45e981877570471f96d4f6e1e865ff9c schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    150 schema:name Algorithms
    151 rdf:type schema:DefinedTerm
    152 N47290c2b11a146958853f5e28e54c570 schema:name dimensions_id
    153 schema:value pub.1032008843
    154 rdf:type schema:PropertyValue
    155 N4a7852a8377c443aa8514646311dfc83 schema:name nlm_unique_id
    156 schema:value 9216904
    157 rdf:type schema:PropertyValue
    158 N4a82691e85d64d399aca28661934b922 rdf:first sg:person.012266613364.42
    159 rdf:rest Ne4bed1203f6b47ca814f10d7704cfe0e
    160 N4bcecadc570845f9bd0481021297c424 rdf:first sg:person.0726250204.50
    161 rdf:rest N3c36893a8a404f1ea35699e59762043c
    162 N4e767dc4dc2a4fb5bdfd9e0962af21bd rdf:first sg:person.01117721120.30
    163 rdf:rest N799b70b8bdf8481f8207ed7061eb2e11
    164 N509bf2d44d554285bf8812efc3998651 schema:name doi
    165 schema:value 10.1038/ng.3401
    166 rdf:type schema:PropertyValue
    167 N58403109a29f438eb7eb6fd80973ca31 rdf:first sg:person.015224655437.42
    168 rdf:rest N6c92bbeb7d5f4571a369d13843c565f4
    169 N5d2770f1eb854b2388291c336a157000 rdf:first sg:person.01313145634.66
    170 rdf:rest N2fe973439c614c52925a64444b328585
    171 N60d57d68c5924392b80dd3c7dce550ea rdf:first sg:person.0756367034.05
    172 rdf:rest Nf7ac88606ac34233bbc2554edf283a00
    173 N64f31919e7514976907b522ca07caa27 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    174 schema:name Genotype
    175 rdf:type schema:DefinedTerm
    176 N65b80d5eeef14ce8b1e98edc215e6014 rdf:first sg:person.0642753276.96
    177 rdf:rest N9fb2d9df5d594bb6b898de51f3112e1b
    178 N6c92bbeb7d5f4571a369d13843c565f4 rdf:first sg:person.012766272254.47
    179 rdf:rest N122df65b53dc4655b2be333fb36fd205
    180 N6f5ae0157e954f4194b5bea2e8c9aaf6 rdf:first sg:person.01110401434.52
    181 rdf:rest N60d57d68c5924392b80dd3c7dce550ea
    182 N70b30f46753b4682a517b7bad8861a26 rdf:first sg:person.01246530370.86
    183 rdf:rest N07cc6806a3e94d5895bab3cf9b9bb319
    184 N71e7688c86a64c3885ad31061ea77cd7 rdf:first sg:person.010700366647.17
    185 rdf:rest N4e767dc4dc2a4fb5bdfd9e0962af21bd
    186 N75dc473263934dbf8381ba44112c3bc9 rdf:first sg:person.0750524661.10
    187 rdf:rest N24a9013edb024e598096d2c894bc0623
    188 N799b70b8bdf8481f8207ed7061eb2e11 rdf:first sg:person.011405001662.87
    189 rdf:rest N75dc473263934dbf8381ba44112c3bc9
    190 N7d5c0185c4474141ab8976cf3f734558 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    191 schema:name Genome-Wide Association Study
    192 rdf:type schema:DefinedTerm
    193 N80c7ac2e67e146e2adb8dab1644296dc schema:name Springer Nature - SN SciGraph project
    194 rdf:type schema:Organization
    195 N87afbf03ee5d419ab3f6eaf127c9b91b schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
    196 schema:familyName Hirschhorn
    197 schema:givenName Joel N
    198 rdf:type schema:Person
    199 N894f13fc121643659b74b8ecda66b084 rdf:first sg:person.01201362637.02
    200 rdf:rest N24095df2c4ba44fdbd160e38960efa10
    201 N89951cbf6574476c8976b6664ee02e0b rdf:first sg:person.0760704165.88
    202 rdf:rest N58403109a29f438eb7eb6fd80973ca31
    203 N8a78164aba214d3782ae204c5d018a8d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    204 schema:name Polymorphism, Single Nucleotide
    205 rdf:type schema:DefinedTerm
    206 N8ae87c61ff3e4ea8b36bbfc7d5c52ab7 schema:issueNumber 11
    207 rdf:type schema:PublicationIssue
    208 N8eca73bd0a3345b198037abeee610399 rdf:first sg:person.0641525362.39
    209 rdf:rest Na9776bfc3b894dae954d79e9d758e03c
    210 N95618f48cf8b4ad1af033317071c3964 rdf:first N9ad81984bd96421b98ae1c28553d132a
    211 rdf:rest Na44338c2ce514af18184facf9730160d
    212 N96888a240a954d78a46e092cbd820916 rdf:first sg:person.0610570026.87
    213 rdf:rest N0b9162dfdd8b45d784fc7c28a973a2bd
    214 N9818ec6b2a0e4841bc85eeb7665ce1c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    215 schema:name Geography
    216 rdf:type schema:DefinedTerm
    217 N9a23f7ca768540a8a08d1185d94787b6 schema:affiliation https://www.grid.ac/institutes/grid.8993.b
    218 schema:familyName Gustafsson
    219 schema:givenName Stefan
    220 rdf:type schema:Person
    221 N9ad81984bd96421b98ae1c28553d132a schema:affiliation https://www.grid.ac/institutes/grid.8391.3
    222 schema:familyName Wood
    223 schema:givenName Andrew R
    224 rdf:type schema:Person
    225 N9fb2d9df5d594bb6b898de51f3112e1b rdf:first Na29a40f078004f49a735d782d5ac6dc1
    226 rdf:rest N165c77c0779a45c59d3d4722a0c5f1ad
    227 Na29a40f078004f49a735d782d5ac6dc1 schema:affiliation https://www.grid.ac/institutes/grid.38142.3c
    228 schema:familyName Esko
    229 schema:givenName Tonu
    230 rdf:type schema:Person
    231 Na44338c2ce514af18184facf9730160d rdf:first sg:person.01167052663.17
    232 rdf:rest N1e673f6cd6154542ad437506881ad645
    233 Na714691bc530441b9740ebd4da65a6bb rdf:first sg:person.01255157234.57
    234 rdf:rest N6f5ae0157e954f4194b5bea2e8c9aaf6
    235 Na9776bfc3b894dae954d79e9d758e03c rdf:first sg:person.0610667722.81
    236 rdf:rest N89951cbf6574476c8976b6664ee02e0b
    237 Nb007060a6ff2455fa864f2f9de4c1185 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    238 schema:name Genetic Variation
    239 rdf:type schema:DefinedTerm
    240 Nb38a825f365549488482bff55cacabe7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    241 schema:name Genetics, Population
    242 rdf:type schema:DefinedTerm
    243 Nb3e4e352d9f84e6b8d63f74464331b2a rdf:first sg:person.0765006250.25
    244 rdf:rest N65b80d5eeef14ce8b1e98edc215e6014
    245 Nb3ea383cfd814d24a71d6fc765501395 rdf:first sg:person.01300757630.84
    246 rdf:rest N5d2770f1eb854b2388291c336a157000
    247 Nbbe6438d59c74eb3bea5f6dc25a9c91e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    248 schema:name Body Mass Index
    249 rdf:type schema:DefinedTerm
    250 Nc75ecfa8f01644ebac0465965432177b rdf:first sg:person.01114462237.40
    251 rdf:rest Nd000673711994ae2bd281a45f364e98e
    252 Ncb2b6e02b8194287b5e5d6994a0c4350 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    253 schema:name Gene Expression Profiling
    254 rdf:type schema:DefinedTerm
    255 Ncc68026a1efa433f8b18717c04d3afd9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    256 schema:name Body Height
    257 rdf:type schema:DefinedTerm
    258 Ncd97f0f0580a497a8a6cd995bb5ae5c9 rdf:first sg:person.01223240773.33
    259 rdf:rest N8eca73bd0a3345b198037abeee610399
    260 Nd000673711994ae2bd281a45f364e98e rdf:first sg:person.01006410206.09
    261 rdf:rest Ncd97f0f0580a497a8a6cd995bb5ae5c9
    262 Nd17dcba378b540378b6e2ed290d93501 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    263 schema:name Gene-Environment Interaction
    264 rdf:type schema:DefinedTerm
    265 Nd72c0198309740f98fe245d9c25d60b2 schema:name pubmed_id
    266 schema:value 26366552
    267 rdf:type schema:PropertyValue
    268 Ndd5c3b7795c947749ed96150a14c7b5a rdf:first N9a23f7ca768540a8a08d1185d94787b6
    269 rdf:rest Na714691bc530441b9740ebd4da65a6bb
    270 Ne1b0568359e74b6fa27d7ea926ceb7f1 rdf:first sg:person.01033044533.08
    271 rdf:rest rdf:nil
    272 Ne4bed1203f6b47ca814f10d7704cfe0e rdf:first sg:person.015576406233.51
    273 rdf:rest N71e7688c86a64c3885ad31061ea77cd7
    274 Neb8c40317f1d4b71bbb40793645198fa rdf:first sg:person.0730724336.65
    275 rdf:rest Ne1b0568359e74b6fa27d7ea926ceb7f1
    276 Nf56a6c9b1bf44ad5a9307de8af061e70 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
    277 schema:name Principal Component Analysis
    278 rdf:type schema:DefinedTerm
    279 Nf7ac88606ac34233bbc2554edf283a00 rdf:first sg:person.01134046226.44
    280 rdf:rest N0e2c586c49eb4adcb48b987043c9b0fc
    281 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
    282 schema:name Biological Sciences
    283 rdf:type schema:DefinedTerm
    284 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
    285 schema:name Genetics
    286 rdf:type schema:DefinedTerm
    287 sg:grant.2443777 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    288 rdf:type schema:MonetaryGrant
    289 sg:grant.2443778 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    290 rdf:type schema:MonetaryGrant
    291 sg:grant.2443780 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    292 rdf:type schema:MonetaryGrant
    293 sg:grant.2443909 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    294 rdf:type schema:MonetaryGrant
    295 sg:grant.2484886 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    296 rdf:type schema:MonetaryGrant
    297 sg:grant.2526608 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    298 rdf:type schema:MonetaryGrant
    299 sg:grant.2669474 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    300 rdf:type schema:MonetaryGrant
    301 sg:grant.2669481 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    302 rdf:type schema:MonetaryGrant
    303 sg:grant.2684560 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    304 rdf:type schema:MonetaryGrant
    305 sg:grant.2686930 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    306 rdf:type schema:MonetaryGrant
    307 sg:grant.2690128 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    308 rdf:type schema:MonetaryGrant
    309 sg:grant.2696437 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    310 rdf:type schema:MonetaryGrant
    311 sg:grant.2758966 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    312 rdf:type schema:MonetaryGrant
    313 sg:grant.3560505 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    314 rdf:type schema:MonetaryGrant
    315 sg:grant.3560622 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    316 rdf:type schema:MonetaryGrant
    317 sg:grant.3567755 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    318 rdf:type schema:MonetaryGrant
    319 sg:grant.3754454 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    320 rdf:type schema:MonetaryGrant
    321 sg:grant.3773756 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    322 rdf:type schema:MonetaryGrant
    323 sg:grant.4113448 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    324 rdf:type schema:MonetaryGrant
    325 sg:grant.4118013 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    326 rdf:type schema:MonetaryGrant
    327 sg:grant.4128757 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    328 rdf:type schema:MonetaryGrant
    329 sg:grant.4137736 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    330 rdf:type schema:MonetaryGrant
    331 sg:grant.4700131 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    332 rdf:type schema:MonetaryGrant
    333 sg:grant.6721191 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    334 rdf:type schema:MonetaryGrant
    335 sg:grant.6736244 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    336 rdf:type schema:MonetaryGrant
    337 sg:grant.6736295 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    338 rdf:type schema:MonetaryGrant
    339 sg:grant.6736536 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.3401
    340 rdf:type schema:MonetaryGrant
    341 sg:journal.1103138 schema:issn 1061-4036
    342 1546-1718
    343 schema:name Nature Genetics
    344 rdf:type schema:Periodical
    345 sg:person.01006410206.09 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    346 schema:familyName Rivadeneira
    347 schema:givenName Fernando
    348 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01006410206.09
    349 rdf:type schema:Person
    350 sg:person.01033044533.08 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    351 schema:familyName Visscher
    352 schema:givenName Peter M
    353 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01033044533.08
    354 rdf:type schema:Person
    355 sg:person.01065017530.29 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    356 schema:familyName Shakhbazov
    357 schema:givenName Konstantin
    358 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01065017530.29
    359 rdf:type schema:Person
    360 sg:person.010700366647.17 schema:affiliation https://www.grid.ac/institutes/grid.1049.c
    361 schema:familyName Martin
    362 schema:givenName Nicholas G
    363 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010700366647.17
    364 rdf:type schema:Person
    365 sg:person.01071450175.91 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    366 schema:familyName Vinkhuyzen
    367 schema:givenName Anna
    368 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01071450175.91
    369 rdf:type schema:Person
    370 sg:person.01110401434.52 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    371 schema:familyName Kahali
    372 schema:givenName Bratati
    373 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01110401434.52
    374 rdf:type schema:Person
    375 sg:person.01114462237.40 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
    376 schema:familyName Veldink
    377 schema:givenName Jan H
    378 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114462237.40
    379 rdf:type schema:Person
    380 sg:person.01117721120.30 schema:affiliation https://www.grid.ac/institutes/grid.1049.c
    381 schema:familyName Montgomery
    382 schema:givenName Grant W
    383 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01117721120.30
    384 rdf:type schema:Person
    385 sg:person.011234570267.86 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    386 schema:familyName Hemani
    387 schema:givenName Gibran
    388 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011234570267.86
    389 rdf:type schema:Person
    390 sg:person.01134046226.44 schema:affiliation https://www.grid.ac/institutes/grid.5170.3
    391 schema:familyName Pers
    392 schema:givenName Tune H
    393 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01134046226.44
    394 rdf:type schema:Person
    395 sg:person.011405001662.87 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
    396 schema:familyName North
    397 schema:givenName Kari E
    398 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011405001662.87
    399 rdf:type schema:Person
    400 sg:person.01145654113.82 schema:affiliation https://www.grid.ac/institutes/grid.270683.8
    401 schema:familyName Ingelsson
    402 schema:givenName Erik
    403 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01145654113.82
    404 rdf:type schema:Person
    405 sg:person.01163250252.90 schema:affiliation https://www.grid.ac/institutes/grid.66859.34
    406 schema:familyName Vedantam
    407 schema:givenName Sailaja
    408 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01163250252.90
    409 rdf:type schema:Person
    410 sg:person.01167052663.17 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
    411 schema:familyName van Rheenen
    412 schema:givenName Wouter
    413 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01167052663.17
    414 rdf:type schema:Person
    415 sg:person.01201362637.02 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    416 schema:familyName Speliotes
    417 schema:givenName Elizabeth K
    418 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01201362637.02
    419 rdf:type schema:Person
    420 sg:person.01223240773.33 schema:affiliation https://www.grid.ac/institutes/grid.452548.a
    421 schema:familyName Werge
    422 schema:givenName Thomas M
    423 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01223240773.33
    424 rdf:type schema:Person
    425 sg:person.012266613364.42 schema:affiliation https://www.grid.ac/institutes/grid.59734.3c
    426 schema:familyName Loos
    427 schema:givenName Ruth J F
    428 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012266613364.42
    429 rdf:type schema:Person
    430 sg:person.01246530370.86 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    431 schema:familyName Powell
    432 schema:givenName Joseph E
    433 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246530370.86
    434 rdf:type schema:Person
    435 sg:person.01255157234.57 schema:affiliation https://www.grid.ac/institutes/grid.10698.36
    436 schema:familyName Justice
    437 schema:givenName Anne E
    438 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01255157234.57
    439 rdf:type schema:Person
    440 sg:person.012631765612.56 schema:affiliation https://www.grid.ac/institutes/grid.13097.3c
    441 schema:familyName Spector
    442 schema:givenName Timothy D
    443 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012631765612.56
    444 rdf:type schema:Person
    445 sg:person.01263457230.91 schema:affiliation N2f670c9106454191990eb9b617526601
    446 schema:familyName Andreassen
    447 schema:givenName Ole A
    448 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01263457230.91
    449 rdf:type schema:Person
    450 sg:person.012766272254.47 schema:affiliation https://www.grid.ac/institutes/grid.8391.3
    451 schema:familyName Frayling
    452 schema:givenName Timothy M
    453 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012766272254.47
    454 rdf:type schema:Person
    455 sg:person.01300757630.84 schema:affiliation https://www.grid.ac/institutes/grid.10306.34
    456 schema:familyName Gasparini
    457 schema:givenName Paolo
    458 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01300757630.84
    459 rdf:type schema:Person
    460 sg:person.01313145634.66 schema:affiliation https://www.grid.ac/institutes/grid.10939.32
    461 schema:familyName Metspalu
    462 schema:givenName Andres
    463 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01313145634.66
    464 rdf:type schema:Person
    465 sg:person.015224655437.42 schema:affiliation https://www.grid.ac/institutes/grid.12380.38
    466 schema:familyName de Geus
    467 schema:givenName Eco J C
    468 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015224655437.42
    469 rdf:type schema:Person
    470 sg:person.015576406233.51 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
    471 schema:familyName Magnusson
    472 schema:givenName Patrik K E
    473 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015576406233.51
    474 rdf:type schema:Person
    475 sg:person.016176207377.25 schema:affiliation https://www.grid.ac/institutes/grid.94365.3d
    476 schema:familyName Berndt
    477 schema:givenName Sonja I
    478 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016176207377.25
    479 rdf:type schema:Person
    480 sg:person.0610570026.87 schema:affiliation https://www.grid.ac/institutes/grid.12380.38
    481 schema:familyName Hottenga
    482 schema:givenName Jouke Jan
    483 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610570026.87
    484 rdf:type schema:Person
    485 sg:person.0610667722.81 schema:affiliation https://www.grid.ac/institutes/grid.12380.38
    486 schema:familyName Boomsma
    487 schema:givenName Dorret I
    488 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0610667722.81
    489 rdf:type schema:Person
    490 sg:person.0623730357.31 schema:affiliation https://www.grid.ac/institutes/grid.1008.9
    491 schema:familyName Goddard
    492 schema:givenName Michael E
    493 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0623730357.31
    494 rdf:type schema:Person
    495 sg:person.0641525362.39 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    496 schema:familyName Abecasis
    497 schema:givenName Goncalo R
    498 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0641525362.39
    499 rdf:type schema:Person
    500 sg:person.0642753276.96 schema:affiliation https://www.grid.ac/institutes/grid.10306.34
    501 schema:familyName Mezzavilla
    502 schema:givenName Massimo
    503 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0642753276.96
    504 rdf:type schema:Person
    505 sg:person.0700316214.32 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
    506 schema:familyName van den Berg
    507 schema:givenName Leonard H
    508 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0700316214.32
    509 rdf:type schema:Person
    510 sg:person.0726250204.50 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    511 schema:familyName Robinson
    512 schema:givenName Matthew R
    513 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0726250204.50
    514 rdf:type schema:Person
    515 sg:person.0730724336.65 schema:affiliation https://www.grid.ac/institutes/grid.1003.2
    516 schema:familyName Yang
    517 schema:givenName Jian
    518 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0730724336.65
    519 rdf:type schema:Person
    520 sg:person.0750524661.10 schema:affiliation https://www.grid.ac/institutes/grid.4714.6
    521 schema:familyName Pedersen
    522 schema:givenName Nancy L
    523 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0750524661.10
    524 rdf:type schema:Person
    525 sg:person.0756367034.05 schema:affiliation https://www.grid.ac/institutes/grid.214458.e
    526 schema:familyName Locke
    527 schema:givenName Adam E
    528 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0756367034.05
    529 rdf:type schema:Person
    530 sg:person.0760704165.88 schema:affiliation https://www.grid.ac/institutes/grid.62560.37
    531 schema:familyName Chasman
    532 schema:givenName Daniel I
    533 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760704165.88
    534 rdf:type schema:Person
    535 sg:person.0765006250.25 schema:affiliation https://www.grid.ac/institutes/grid.5645.2
    536 schema:familyName Medina-Gomez
    537 schema:givenName Carolina
    538 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0765006250.25
    539 rdf:type schema:Person
    540 sg:pub.10.1038/ejhg.2009.177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003075684
    541 https://doi.org/10.1038/ejhg.2009.177
    542 rdf:type schema:CreativeWork
    543 sg:pub.10.1038/ejhg.2012.229 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030585304
    544 https://doi.org/10.1038/ejhg.2012.229
    545 rdf:type schema:CreativeWork
    546 sg:pub.10.1038/nature04240 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041792930
    547 https://doi.org/10.1038/nature04240
    548 rdf:type schema:CreativeWork
    549 sg:pub.10.1038/nature06250 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036876479
    550 https://doi.org/10.1038/nature06250
    551 rdf:type schema:CreativeWork
    552 sg:pub.10.1038/nature09410 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037714920
    553 https://doi.org/10.1038/nature09410
    554 rdf:type schema:CreativeWork
    555 sg:pub.10.1038/nature11401 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024448471
    556 https://doi.org/10.1038/nature11401
    557 rdf:type schema:CreativeWork
    558 sg:pub.10.1038/nature11632 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000661742
    559 https://doi.org/10.1038/nature11632
    560 rdf:type schema:CreativeWork
    561 sg:pub.10.1038/nature14177 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053003561
    562 https://doi.org/10.1038/nature14177
    563 rdf:type schema:CreativeWork
    564 sg:pub.10.1038/ng.2213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006110604
    565 https://doi.org/10.1038/ng.2213
    566 rdf:type schema:CreativeWork
    567 sg:pub.10.1038/ng.2368 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010777696
    568 https://doi.org/10.1038/ng.2368
    569 rdf:type schema:CreativeWork
    570 sg:pub.10.1038/ng.2383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011024359
    571 https://doi.org/10.1038/ng.2383
    572 rdf:type schema:CreativeWork
    573 sg:pub.10.1038/ng.3097 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006357119
    574 https://doi.org/10.1038/ng.3097
    575 rdf:type schema:CreativeWork
    576 sg:pub.10.1038/ng.608 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015057090
    577 https://doi.org/10.1038/ng.608
    578 rdf:type schema:CreativeWork
    579 sg:pub.10.1038/ng.686 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013643799
    580 https://doi.org/10.1038/ng.686
    581 rdf:type schema:CreativeWork
    582 sg:pub.10.1038/ng.78 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020863803
    583 https://doi.org/10.1038/ng.78
    584 rdf:type schema:CreativeWork
    585 sg:pub.10.1038/nmeth.1785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002640757
    586 https://doi.org/10.1038/nmeth.1785
    587 rdf:type schema:CreativeWork
    588 sg:pub.10.1038/nrg2187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002543859
    589 https://doi.org/10.1038/nrg2187
    590 rdf:type schema:CreativeWork
    591 sg:pub.10.1038/nrg2698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001355162
    592 https://doi.org/10.1038/nrg2698
    593 rdf:type schema:CreativeWork
    594 sg:pub.10.1038/nrg3395 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022150201
    595 https://doi.org/10.1038/nrg3395
    596 rdf:type schema:CreativeWork
    597 https://doi.org/10.1001/jama.282.7.677 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047685348
    598 rdf:type schema:CreativeWork
    599 https://doi.org/10.1002/ajpa.20107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004938254
    600 rdf:type schema:CreativeWork
    601 https://doi.org/10.1016/j.ajhg.2012.06.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024911758
    602 rdf:type schema:CreativeWork
    603 https://doi.org/10.1016/j.cub.2008.04.074 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009456892
    604 rdf:type schema:CreativeWork
    605 https://doi.org/10.1016/j.cub.2009.11.055 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051673317
    606 rdf:type schema:CreativeWork
    607 https://doi.org/10.1016/j.tig.2014.02.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044265637
    608 rdf:type schema:CreativeWork
    609 https://doi.org/10.1016/s0140-6736(06)68770-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006956756
    610 rdf:type schema:CreativeWork
    611 https://doi.org/10.1016/s0140-6736(07)61415-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053711949
    612 rdf:type schema:CreativeWork
    613 https://doi.org/10.1016/s0140-6736(07)61696-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005365609
    614 rdf:type schema:CreativeWork
    615 https://doi.org/10.1016/s0140-6736(10)62037-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021970749
    616 rdf:type schema:CreativeWork
    617 https://doi.org/10.1016/s0140-6736(11)60814-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025087671
    618 rdf:type schema:CreativeWork
    619 https://doi.org/10.1016/s0140-6736(12)61719-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025534845
    620 rdf:type schema:CreativeWork
    621 https://doi.org/10.1016/s0140-6736(14)60460-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007350540
    622 rdf:type schema:CreativeWork
    623 https://doi.org/10.1016/s1474-4422(09)70023-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028300612
    624 rdf:type schema:CreativeWork
    625 https://doi.org/10.1073/pnas.0906182107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022731697
    626 rdf:type schema:CreativeWork
    627 https://doi.org/10.1073/pnas.0910803106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051439634
    628 rdf:type schema:CreativeWork
    629 https://doi.org/10.1073/pnas.84.23.8512 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051608823
    630 rdf:type schema:CreativeWork
    631 https://doi.org/10.1080/20780389.2012.657489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051662195
    632 rdf:type schema:CreativeWork
    633 https://doi.org/10.1086/283642 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058593765
    634 rdf:type schema:CreativeWork
    635 https://doi.org/10.1086/302698 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058610264
    636 rdf:type schema:CreativeWork
    637 https://doi.org/10.1086/519795 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019061180
    638 rdf:type schema:CreativeWork
    639 https://doi.org/10.1093/ajcn/84.1.289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077281125
    640 rdf:type schema:CreativeWork
    641 https://doi.org/10.1093/hmg/dds491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006408755
    642 rdf:type schema:CreativeWork
    643 https://doi.org/10.1097/01.hjr.0000114707.27531.48 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060329945
    644 rdf:type schema:CreativeWork
    645 https://doi.org/10.1111/eva.12045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035837962
    646 rdf:type schema:CreativeWork
    647 https://doi.org/10.1111/evo.12268 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001568892
    648 rdf:type schema:CreativeWork
    649 https://doi.org/10.1126/science.1227001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062467000
    650 rdf:type schema:CreativeWork
    651 https://doi.org/10.1146/annurev.genet.36.050802.093940 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012760112
    652 rdf:type schema:CreativeWork
    653 https://doi.org/10.1158/1055-9965.epi-10-0437 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040210484
    654 rdf:type schema:CreativeWork
    655 https://doi.org/10.1161/circulationaha.111.018820 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039416458
    656 rdf:type schema:CreativeWork
    657 https://doi.org/10.1161/strokeaha.111.000067 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012257344
    658 rdf:type schema:CreativeWork
    659 https://doi.org/10.1371/journal.pbio.0020286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044097460
    660 rdf:type schema:CreativeWork
    661 https://doi.org/10.1371/journal.pgen.1000008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037949611
    662 rdf:type schema:CreativeWork
    663 https://doi.org/10.1371/journal.pgen.1003348 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023968606
    664 rdf:type schema:CreativeWork
    665 https://doi.org/10.1371/journal.pgen.1003355 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019838558
    666 rdf:type schema:CreativeWork
    667 https://doi.org/10.1371/journal.pgen.1004412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004866588
    668 rdf:type schema:CreativeWork
    669 https://doi.org/10.1371/journal.pone.0027588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032264196
    670 rdf:type schema:CreativeWork
    671 https://doi.org/10.1371/journal.pone.0049837 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021842939
    672 rdf:type schema:CreativeWork
    673 https://doi.org/10.1534/g3.111.001198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037455212
    674 rdf:type schema:CreativeWork
    675 https://doi.org/10.1534/genetics.111.129387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040195285
    676 rdf:type schema:CreativeWork
    677 https://doi.org/10.1534/genetics.112.144758 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050687048
    678 rdf:type schema:CreativeWork
    679 https://doi.org/10.18637/jss.v033.i02 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068672497
    680 rdf:type schema:CreativeWork
    681 https://doi.org/10.2307/2408641 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069917637
    682 rdf:type schema:CreativeWork
    683 https://doi.org/10.2337/diacare.27.5.1047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051349743
    684 rdf:type schema:CreativeWork
    685 https://www.grid.ac/institutes/grid.1003.2 schema:alternateName University of Queensland
    686 schema:name Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia.
    687 University of Queensland Diamantina Institute, University of Queensland, Translational Research Institute, Brisbane, Queensland, Australia.
    688 rdf:type schema:Organization
    689 https://www.grid.ac/institutes/grid.1008.9 schema:alternateName University of Melbourne
    690 schema:name Biosciences Research Division, Department of Primary Industries, Melbourne, Victoria, Australia.
    691 Department of Food and Agricultural Systems, University of Melbourne, Melbourne, Victoria, Australia.
    692 rdf:type schema:Organization
    693 https://www.grid.ac/institutes/grid.10306.34 schema:alternateName Wellcome Sanger Institute
    694 schema:name Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy.
    695 Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.
    696 rdf:type schema:Organization
    697 https://www.grid.ac/institutes/grid.1049.c schema:alternateName QIMR Berghofer Medical Research Institute
    698 schema:name QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.
    699 rdf:type schema:Organization
    700 https://www.grid.ac/institutes/grid.10698.36 schema:alternateName University of North Carolina at Chapel Hill
    701 schema:name Carolina Center for Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
    702 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
    703 Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
    704 Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
    705 rdf:type schema:Organization
    706 https://www.grid.ac/institutes/grid.10939.32 schema:alternateName University of Tartu
    707 schema:name Estonian Genome Center, University of Tartu, Tartu, Estonia.
    708 rdf:type schema:Organization
    709 https://www.grid.ac/institutes/grid.12380.38 schema:alternateName VU University Amsterdam
    710 schema:name Department of Biological Psychology, VU University Amsterdam, Amsterdam, the Netherlands.
    711 EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
    712 Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
    713 rdf:type schema:Organization
    714 https://www.grid.ac/institutes/grid.13097.3c schema:alternateName King's College London
    715 schema:name Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Hospital, London, UK.
    716 rdf:type schema:Organization
    717 https://www.grid.ac/institutes/grid.214458.e schema:alternateName University of Michigan–Ann Arbor
    718 schema:name Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA.
    719 Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA.
    720 Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
    721 rdf:type schema:Organization
    722 https://www.grid.ac/institutes/grid.270683.8 schema:alternateName Wellcome Centre for Human Genetics
    723 schema:name Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
    724 Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
    725 rdf:type schema:Organization
    726 https://www.grid.ac/institutes/grid.38142.3c schema:alternateName Harvard University
    727 schema:name Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
    728 Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.
    729 Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
    730 Estonian Genome Center, University of Tartu, Tartu, Estonia.
    731 rdf:type schema:Organization
    732 https://www.grid.ac/institutes/grid.452548.a schema:alternateName Lundbeck Foundation
    733 schema:name Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
    734 Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Devices Copenhagen, Roskilde, Denmark.
    735 Lundbeck Foundation Initiative for Integrative Psychiatric Research, (iPSYCH), Aarhus, Denmark.
    736 rdf:type schema:Organization
    737 https://www.grid.ac/institutes/grid.4714.6 schema:alternateName Karolinska Institute
    738 schema:name Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
    739 rdf:type schema:Organization
    740 https://www.grid.ac/institutes/grid.5170.3 schema:alternateName Technical University of Denmark
    741 schema:name Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
    742 Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.
    743 Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark.
    744 Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
    745 rdf:type schema:Organization
    746 https://www.grid.ac/institutes/grid.5645.2 schema:alternateName Erasmus University Medical Center
    747 schema:name Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands.
    748 rdf:type schema:Organization
    749 https://www.grid.ac/institutes/grid.59734.3c schema:alternateName Icahn School of Medicine at Mount Sinai
    750 schema:name Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    751 Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    752 Medical Research Council (MRC) Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.
    753 Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    754 rdf:type schema:Organization
    755 https://www.grid.ac/institutes/grid.62560.37 schema:alternateName Brigham and Women's Hospital
    756 schema:name Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.
    757 Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
    758 rdf:type schema:Organization
    759 https://www.grid.ac/institutes/grid.66859.34 schema:alternateName Broad Institute
    760 schema:name Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
    761 Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.
    762 rdf:type schema:Organization
    763 https://www.grid.ac/institutes/grid.7692.a schema:alternateName University Medical Center Utrecht
    764 schema:name Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.
    765 rdf:type schema:Organization
    766 https://www.grid.ac/institutes/grid.8391.3 schema:alternateName University of Exeter
    767 schema:name Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK.
    768 rdf:type schema:Organization
    769 https://www.grid.ac/institutes/grid.8993.b schema:alternateName Uppsala University
    770 schema:name Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
    771 rdf:type schema:Organization
    772 https://www.grid.ac/institutes/grid.94365.3d schema:alternateName National Institutes of Health
    773 schema:name Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, Bethesda, Maryland, USA.
    774 rdf:type schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...