A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2009-02-15

AUTHORS

Sonia A Melo, Santiago Ropero, Catia Moutinho, Lauri A Aaltonen, Hiroyuki Yamamoto, George A Calin, Simona Rossi, Agustin F Fernandez, Fatima Carneiro, Carla Oliveira, Bibiana Ferreira, Chang-Gong Liu, Alberto Villanueva, Gabriel Capella, Simo Schwartz Jr, Ramin Shiekhattar, Manel Esteller

ABSTRACT

Manel Esteller and colleagues report truncating mutations in TARBP2, an integral component of a DICER1-containing complex, in human colorectal cancers. This is the first report of a mutation in one of the genes involved in miRNA processing in human cancer.

PAGES

365-370

Journal

TITLE

Nature Genetics

ISSUE

3

VOLUME

41

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng.317

DOI

http://dx.doi.org/10.1038/ng.317

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1045309569

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19219043


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