Ontology type: schema:ScholarlyArticle
2014-12-15
AUTHORSAntonio Adamo, Sina Atashpaz, Pierre-Luc Germain, Matteo Zanella, Giuseppe D'Agostino, Veronica Albertin, Josh Chenoweth, Lucia Micale, Carmela Fusco, Christian Unger, Bartolomeo Augello, Orazio Palumbo, Brad Hamilton, Massimo Carella, Emilio Donti, Giancarlo Pruneri, Angelo Selicorni, Elisa Biamino, Paolo Prontera, Ronald McKay, Giuseppe Merla, Giuseppe Testa
ABSTRACTGiuseppe Testa and colleagues report the generation and transcriptional characterization of patient-derived induced pluripotent stem cells (iPSCs) with copy number variants at 7q11.23, which cause syndromes including neurocognitive phenotypes. They find that the dosage of the transcription factor gene GTF2I accounts for 10–20% of the transcriptional dysregulation observed in these cells. More... »
PAGES132-141
http://scigraph.springernature.com/pub.10.1038/ng.3169
DOIhttp://dx.doi.org/10.1038/ng.3169
DIMENSIONShttps://app.dimensions.ai/details/publication/pub.1013944922
PUBMEDhttps://www.ncbi.nlm.nih.gov/pubmed/25501393
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Biological Sciences",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"name": "Genetics",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Differentiation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cell Lineage",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Chromosomes, Human, Pair 7",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Cohort Studies",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Comparative Genomic Hybridization",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "DNA Copy Number Variations",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Dosage",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Duplication",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Expression Profiling",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Gene Expression Regulation",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Histone Demethylases",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Humans",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Oligonucleotide Array Sequence Analysis",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Phenotype",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Pluripotent Stem Cells",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Sequence Analysis, RNA",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Transcription Factors, TFII",
"type": "DefinedTerm"
},
{
"inDefinedTermSet": "https://www.nlm.nih.gov/mesh/",
"name": "Williams Syndrome",
"type": "DefinedTerm"
}
],
"author": [
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Adamo",
"givenName": "Antonio",
"id": "sg:person.01216765332.34",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01216765332.34"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Atashpaz",
"givenName": "Sina",
"id": "sg:person.01172127230.16",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01172127230.16"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Germain",
"givenName": "Pierre-Luc",
"id": "sg:person.01035674114.74",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01035674114.74"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Zanella",
"givenName": "Matteo",
"id": "sg:person.01221421460.42",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01221421460.42"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "D'Agostino",
"givenName": "Giuseppe",
"id": "sg:person.015721127731.53",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015721127731.53"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Albertin",
"givenName": "Veronica",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Lieber Institute for Brain Development, Baltimore, Maryland, USA",
"id": "http://www.grid.ac/institutes/grid.429552.d",
"name": [
"Lieber Institute for Brain Development, Baltimore, Maryland, USA"
],
"type": "Organization"
},
"familyName": "Chenoweth",
"givenName": "Josh",
"id": "sg:person.015142435327.04",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015142435327.04"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Micale",
"givenName": "Lucia",
"id": "sg:person.0746744502.41",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0746744502.41"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Fusco",
"givenName": "Carmela",
"id": "sg:person.01212413536.64",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01212413536.64"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Biomedical Sciences, University of Sheffield, Sheffield, UK",
"id": "http://www.grid.ac/institutes/grid.11835.3e",
"name": [
"Department of Biomedical Sciences, University of Sheffield, Sheffield, UK"
],
"type": "Organization"
},
"familyName": "Unger",
"givenName": "Christian",
"id": "sg:person.0751564147.61",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0751564147.61"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Augello",
"givenName": "Bartolomeo",
"id": "sg:person.01177421502.28",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01177421502.28"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Palumbo",
"givenName": "Orazio",
"id": "sg:person.01324145556.42",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01324145556.42"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Stemgent, Cambridge, Massachusetts, USA",
"id": "http://www.grid.ac/institutes/None",
"name": [
"Stemgent, Cambridge, Massachusetts, USA"
],
"type": "Organization"
},
"familyName": "Hamilton",
"givenName": "Brad",
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Carella",
"givenName": "Massimo",
"id": "sg:person.0701537353.17",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0701537353.17"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy",
"id": "http://www.grid.ac/institutes/grid.9027.c",
"name": [
"Medical Genetics Unit, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy"
],
"type": "Organization"
},
"familyName": "Donti",
"givenName": "Emilio",
"id": "sg:person.0760205347.04",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0760205347.04"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.414603.4",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy"
],
"type": "Organization"
},
"familyName": "Pruneri",
"givenName": "Giancarlo",
"id": "sg:person.01232050025.49",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232050025.49"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Unit\u00e0 Operativa Semplice (UOS) Genetica Clinica Pediatrica, Fondazione Monza e Brianza per il Bambino e la sua Mamma (Fondazione MBBM), Azienda Ospedaliera San Gerardo, Monza, Italy",
"id": "http://www.grid.ac/institutes/grid.415025.7",
"name": [
"Unit\u00e0 Operativa Semplice (UOS) Genetica Clinica Pediatrica, Fondazione Monza e Brianza per il Bambino e la sua Mamma (Fondazione MBBM), Azienda Ospedaliera San Gerardo, Monza, Italy"
],
"type": "Organization"
},
"familyName": "Selicorni",
"givenName": "Angelo",
"id": "sg:person.01215142600.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215142600.01"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Pediatrics, University of Turin, Turin, Italy",
"id": "http://www.grid.ac/institutes/grid.7605.4",
"name": [
"Department of Pediatrics, University of Turin, Turin, Italy"
],
"type": "Organization"
},
"familyName": "Biamino",
"givenName": "Elisa",
"id": "sg:person.01317421753.43",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01317421753.43"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy",
"id": "http://www.grid.ac/institutes/grid.9027.c",
"name": [
"Medical Genetics Unit, Hospital Santa Maria della Misericordia, University of Perugia, Perugia, Italy"
],
"type": "Organization"
},
"familyName": "Prontera",
"givenName": "Paolo",
"id": "sg:person.01350041732.31",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01350041732.31"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Lieber Institute for Brain Development, Baltimore, Maryland, USA",
"id": "http://www.grid.ac/institutes/grid.429552.d",
"name": [
"Lieber Institute for Brain Development, Baltimore, Maryland, USA"
],
"type": "Organization"
},
"familyName": "McKay",
"givenName": "Ronald",
"id": "sg:person.010146555477.22",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010146555477.22"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy",
"id": "http://www.grid.ac/institutes/grid.413503.0",
"name": [
"Medical Genetics Unit, IRCCS Casa Sollievo della Sofferenza Hospital, San Giovanni Rotondo, Italy"
],
"type": "Organization"
},
"familyName": "Merla",
"givenName": "Giuseppe",
"id": "sg:person.0666654566.01",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0666654566.01"
],
"type": "Person"
},
{
"affiliation": {
"alternateName": "Department of Health Sciences, University of Milan, Milan, Italy",
"id": "http://www.grid.ac/institutes/grid.4708.b",
"name": [
"Department of Experimental Oncology, European Institute of Oncology (Istituto di Ricovero e Cura a Carattere Scientifico, IRCCS), Milan, Italy",
"Department of Health Sciences, University of Milan, Milan, Italy"
],
"type": "Organization"
},
"familyName": "Testa",
"givenName": "Giuseppe",
"id": "sg:person.01232530660.59",
"sameAs": [
"https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01232530660.59"
],
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1007/s00439-010-0827-2",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023549217",
"https://doi.org/10.1007/s00439-010-0827-2"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nprot.2012.156",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1000883700",
"https://doi.org/10.1038/nprot.2012.156"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nrm3584",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1017295221",
"https://doi.org/10.1038/nrm3584"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature13551",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1021458311",
"https://doi.org/10.1038/nature13551"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nprot.2013.023",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050194372",
"https://doi.org/10.1038/nprot.2013.023"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nn.3041",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044160054",
"https://doi.org/10.1038/nn.3041"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb2246",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043979680",
"https://doi.org/10.1038/ncb2246"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11629",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1002086310",
"https://doi.org/10.1038/nature11629"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nprot.2007.261",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1048442956",
"https://doi.org/10.1038/nprot.2007.261"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10803-014-2117-7",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1050846140",
"https://doi.org/10.1007/s10803-014-2117-7"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nbt1310",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1024578139",
"https://doi.org/10.1038/nbt1310"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s00439-010-0817-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1023066114",
"https://doi.org/10.1007/s00439-010-0817-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s10803-011-1389-4",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011373838",
"https://doi.org/10.1007/s10803-011-1389-4"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nprot.2012.116",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1043421085",
"https://doi.org/10.1038/nprot.2012.116"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/cdd.2011.9",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1039195900",
"https://doi.org/10.1038/cdd.2011.9"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1007/s007870070035",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1001454449",
"https://doi.org/10.1007/s007870070035"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ejhg.2013.101",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1007560194",
"https://doi.org/10.1038/ejhg.2013.101"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nn.3801",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1052242395",
"https://doi.org/10.1038/nn.3801"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ejhg.2009.108",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015150441",
"https://doi.org/10.1038/ejhg.2009.108"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature11405",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1044384575",
"https://doi.org/10.1038/nature11405"
],
"type": "CreativeWork"
}
],
"datePublished": "2014-12-15",
"datePublishedReg": "2014-12-15",
"description": "Giuseppe Testa and colleagues report the generation and transcriptional characterization of patient-derived induced pluripotent stem cells (iPSCs) with copy number variants at 7q11.23, which cause syndromes including neurocognitive phenotypes. They find that the dosage of the transcription factor gene GTF2I accounts for 10\u201320% of the transcriptional dysregulation observed in these cells.",
"genre": "article",
"id": "sg:pub.10.1038/ng.3169",
"inLanguage": "en",
"isAccessibleForFree": false,
"isFundedItemOf": [
{
"id": "sg:grant.3801072",
"type": "MonetaryGrant"
},
{
"id": "sg:grant.5150384",
"type": "MonetaryGrant"
}
],
"isPartOf": [
{
"id": "sg:journal.1103138",
"issn": [
"1061-4036",
"1546-1718"
],
"name": "Nature Genetics",
"publisher": "Springer Nature",
"type": "Periodical"
},
{
"issueNumber": "2",
"type": "PublicationIssue"
},
{
"type": "PublicationVolume",
"volumeNumber": "47"
}
],
"keywords": [
"induced pluripotent stem cells",
"pluripotent stem cells",
"stem cells",
"patient-derived induced pluripotent stem cells",
"human pluripotent stem cells",
"transcriptional characterization",
"transcriptional programs",
"copy number variants",
"transcriptional dysregulation",
"number variants",
"cells",
"dysregulation",
"lineages",
"testa",
"phenotype",
"neurocognitive phenotype",
"variants",
"characterization",
"generation",
"syndrome",
"program",
"dosage",
"colleagues",
"account"
],
"name": "7q11.23 dosage-dependent dysregulation in human pluripotent stem cells affects transcriptional programs in disease-relevant lineages",
"pagination": "132-141",
"productId": [
{
"name": "dimensions_id",
"type": "PropertyValue",
"value": [
"pub.1013944922"
]
},
{
"name": "doi",
"type": "PropertyValue",
"value": [
"10.1038/ng.3169"
]
},
{
"name": "pubmed_id",
"type": "PropertyValue",
"value": [
"25501393"
]
}
],
"sameAs": [
"https://doi.org/10.1038/ng.3169",
"https://app.dimensions.ai/details/publication/pub.1013944922"
],
"sdDataset": "articles",
"sdDatePublished": "2022-05-20T07:29",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220519/entities/gbq_results/article/article_629.jsonl",
"type": "ScholarlyArticle",
"url": "https://doi.org/10.1038/ng.3169"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.3169'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.3169'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.3169'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.3169'
This table displays all metadata directly associated to this object as RDF triples.
412 TRIPLES
22 PREDICATES
88 URIs
60 LITERALS
25 BLANK NODES