Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2013-12

AUTHORS

Yuchen Jiao, Timothy M Pawlik, Robert A Anders, Florin M Selaru, Mirte M Streppel, Donald J Lucas, Noushin Niknafs, Violeta Beleva Guthrie, Anirban Maitra, Pedram Argani, G Johan A Offerhaus, Juan Carlos Roa, Lewis R Roberts, Gregory J Gores, Irinel Popescu, Sorin T Alexandrescu, Simona Dima, Matteo Fassan, Michele Simbolo, Andrea Mafficini, Paola Capelli, Rita T Lawlor, Andrea Ruzzenente, Alfredo Guglielmi, Giampaolo Tortora, Filippo de Braud, Aldo Scarpa, William Jarnagin, David Klimstra, Rachel Karchin, Victor E Velculescu, Ralph H Hruban, Bert Vogelstein, Kenneth W Kinzler, Nickolas Papadopoulos, Laura D Wood

ABSTRACT

Through exomic sequencing of 32 intrahepatic cholangiocarcinomas, we discovered frequent inactivating mutations in multiple chromatin-remodeling genes (including BAP1, ARID1A and PBRM1), and mutation in one of these genes occurred in almost half of the carcinomas sequenced. We also identified frequent mutations at previously reported hotspots in the IDH1 and IDH2 genes encoding metabolic enzymes in intrahepatic cholangiocarcinomas. In contrast, TP53 was the most frequently altered gene in a series of nine gallbladder carcinomas. These discoveries highlight the key role of dysregulated chromatin remodeling in intrahepatic cholangiocarcinomas. More... »

PAGES

1470-1473

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng.2813

DOI

http://dx.doi.org/10.1038/ng.2813

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1049645772

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/24185509


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile Duct Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Bile Ducts, Intrahepatic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cholangiocarcinoma", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Exome", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Gene Frequency", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Liver Neoplasms", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Mutation, Missense", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Nuclear Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Sequence Analysis, DNA", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Survival Analysis", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Transcription Factors", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Tumor Suppressor Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Ubiquitin Thiolesterase", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Medicine", 
          "id": "https://www.grid.ac/institutes/grid.469474.c", 
          "name": [
            "The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jiao", 
        "givenName": "Yuchen", 
        "id": "sg:person.0631663776.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631663776.31"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.", 
            "Department of Surgery, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Pawlik", 
        "givenName": "Timothy M", 
        "id": "sg:person.0721627074.41", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.", 
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Anders", 
        "givenName": "Robert A", 
        "id": "sg:person.01210010423.38", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210010423.38"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Selaru", 
        "givenName": "Florin M", 
        "id": "sg:person.01174147316.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174147316.99"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Streppel", 
        "givenName": "Mirte M", 
        "id": "sg:person.0620255165.48", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620255165.48"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Walter Reed National Military Medical Center", 
          "id": "https://www.grid.ac/institutes/grid.414467.4", 
          "name": [
            "Department of Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lucas", 
        "givenName": "Donald J", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Niknafs", 
        "givenName": "Noushin", 
        "id": "sg:person.01213310466.21", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213310466.21"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guthrie", 
        "givenName": "Violeta Beleva", 
        "id": "sg:person.01171343404.33", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171343404.33"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.", 
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Maitra", 
        "givenName": "Anirban", 
        "id": "sg:person.01246576774.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246576774.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.", 
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Argani", 
        "givenName": "Pedram", 
        "id": "sg:person.010340527017.07", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010340527017.07"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University Medical Center Utrecht", 
          "id": "https://www.grid.ac/institutes/grid.7692.a", 
          "name": [
            "Department of Pathology, University Medical Center, Utrecht, The Netherlands."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Offerhaus", 
        "givenName": "G Johan A", 
        "id": "sg:person.014561616077.23", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014561616077.23"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of La Frontera", 
          "id": "https://www.grid.ac/institutes/grid.412163.3", 
          "name": [
            "Department of Pathology, Universidad de La Frontera, Temuco, Chile."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roa", 
        "givenName": "Juan Carlos", 
        "id": "sg:person.01326154272.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326154272.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mayo Clinic", 
          "id": "https://www.grid.ac/institutes/grid.66875.3a", 
          "name": [
            "Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Roberts", 
        "givenName": "Lewis R", 
        "id": "sg:person.016670317257.91", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016670317257.91"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Mayo Clinic", 
          "id": "https://www.grid.ac/institutes/grid.66875.3a", 
          "name": [
            "Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Gores", 
        "givenName": "Gregory J", 
        "id": "sg:person.07702206317.64", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07702206317.64"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institutul Clinic Fundeni", 
          "id": "https://www.grid.ac/institutes/grid.415180.9", 
          "name": [
            "Dan Setlacec Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Popescu", 
        "givenName": "Irinel", 
        "id": "sg:person.0660433203.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660433203.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institutul Clinic Fundeni", 
          "id": "https://www.grid.ac/institutes/grid.415180.9", 
          "name": [
            "Dan Setlacec Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Alexandrescu", 
        "givenName": "Sorin T", 
        "id": "sg:person.0714157340.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714157340.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Institutul Clinic Fundeni", 
          "id": "https://www.grid.ac/institutes/grid.415180.9", 
          "name": [
            "Dan Setlacec Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Dima", 
        "givenName": "Simona", 
        "id": "sg:person.0632617652.16", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632617652.16"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy.", 
            "Department of Pathology and Diagnostics, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Fassan", 
        "givenName": "Matteo", 
        "id": "sg:person.01215230032.09", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215230032.09"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy.", 
            "Department of Pathology and Diagnostics, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Simbolo", 
        "givenName": "Michele", 
        "id": "sg:person.01102666143.51", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102666143.51"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Mafficini", 
        "givenName": "Andrea", 
        "id": "sg:person.0602412452.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602412452.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Department of Pathology and Diagnostics, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Capelli", 
        "givenName": "Paola", 
        "id": "sg:person.01162514032.19", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162514032.19"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy.", 
            "Department of Pathology and Diagnostics, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Lawlor", 
        "givenName": "Rita T", 
        "id": "sg:person.0632553362.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632553362.25"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Department of Surgery, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Ruzzenente", 
        "givenName": "Andrea", 
        "id": "sg:person.0625050266.98", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625050266.98"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Department of Surgery, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Guglielmi", 
        "givenName": "Alfredo", 
        "id": "sg:person.01050022401.71", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050022401.71"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Department of Medicine, Medical Oncology Unit, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Tortora", 
        "givenName": "Giampaolo", 
        "id": "sg:person.01122564664.32", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122564664.32"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Istituto Nazionale dei Tumori", 
          "id": "https://www.grid.ac/institutes/grid.417893.0", 
          "name": [
            "Medical Oncology Unit 1, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "de Braud", 
        "givenName": "Filippo", 
        "id": "sg:person.0660154036.65", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660154036.65"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "University of Verona", 
          "id": "https://www.grid.ac/institutes/grid.5611.3", 
          "name": [
            "Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy.", 
            "Department of Pathology and Diagnostics, University of Verona, Verona, Italy."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Scarpa", 
        "givenName": "Aldo", 
        "id": "sg:person.012622657362.12", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012622657362.12"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Memorial Sloan Kettering Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.51462.34", 
          "name": [
            "Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Jarnagin", 
        "givenName": "William", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Memorial Sloan Kettering Cancer Center", 
          "id": "https://www.grid.ac/institutes/grid.51462.34", 
          "name": [
            "Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Klimstra", 
        "givenName": "David", 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Karchin", 
        "givenName": "Rachel", 
        "id": "sg:person.0651153564.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651153564.24"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Medicine", 
          "id": "https://www.grid.ac/institutes/grid.469474.c", 
          "name": [
            "The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Velculescu", 
        "givenName": "Victor E", 
        "id": "sg:person.010354303077.37", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010354303077.37"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.", 
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Hruban", 
        "givenName": "Ralph H", 
        "id": "sg:person.07624111077.08", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07624111077.08"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Medicine", 
          "id": "https://www.grid.ac/institutes/grid.469474.c", 
          "name": [
            "The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Vogelstein", 
        "givenName": "Bert", 
        "id": "sg:person.011173760757.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011173760757.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Medicine", 
          "id": "https://www.grid.ac/institutes/grid.469474.c", 
          "name": [
            "The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kinzler", 
        "givenName": "Kenneth W", 
        "id": "sg:person.0620642630.54", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620642630.54"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins Medicine", 
          "id": "https://www.grid.ac/institutes/grid.469474.c", 
          "name": [
            "The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.", 
            "Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Papadopoulos", 
        "givenName": "Nickolas", 
        "id": "sg:person.013623242142.34", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013623242142.34"
        ], 
        "type": "Person"
      }, 
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA."
          ], 
          "type": "Organization"
        }, 
        "familyName": "Wood", 
        "givenName": "Laura D", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/sj.onc.1210529", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000136651", 
          "https://doi.org/10.1038/sj.onc.1210529"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1133427", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000786924"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.biopha.2010.06.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004851269"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.2011-0386", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008469500"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09639", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009539954", 
          "https://doi.org/10.1038/nature09639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1053/j.gastro.2009.02.038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013903203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/11315680-000000000-00000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014688288", 
          "https://doi.org/10.2165/11315680-000000000-00000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/11315680-000000000-00000", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014688288", 
          "https://doi.org/10.2165/11315680-000000000-00000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.humpath.2012.11.006", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017260131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.1139", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017581467"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pat.0b013e32835d0efb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031538966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pat.0b013e32835d0efb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031538966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/pat.0b013e32835d0efb", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031538966"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1056/nejmoa0808710", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035319148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrgastro.2011.131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037668976", 
          "https://doi.org/10.1038/nrgastro.2011.131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/humu.21633", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042168641"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/onc.2012.315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046269452", 
          "https://doi.org/10.1038/onc.2012.315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048324405", 
          "https://doi.org/10.1038/nature09208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00268-004-7447-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051594530", 
          "https://doi.org/10.1007/s00268-004-7447-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1097/01.mp.0000062656.60581.aa", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052182241", 
          "https://doi.org/10.1097/01.mp.0000062656.60581.aa"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2159-8290.cd-13-0050", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052822978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.2273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053156141", 
          "https://doi.org/10.1038/ng.2273"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2466/pr0.95.2.449-458", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070823125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2466/pr0.95.2.449-458", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070823125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1074763329", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-12", 
    "datePublishedReg": "2013-12-01", 
    "description": "Through exomic sequencing of 32 intrahepatic cholangiocarcinomas, we discovered frequent inactivating mutations in multiple chromatin-remodeling genes (including BAP1, ARID1A and PBRM1), and mutation in one of these genes occurred in almost half of the carcinomas sequenced. We also identified frequent mutations at previously reported hotspots in the IDH1 and IDH2 genes encoding metabolic enzymes in intrahepatic cholangiocarcinomas. In contrast, TP53 was the most frequently altered gene in a series of nine gallbladder carcinomas. These discoveries highlight the key role of dysregulated chromatin remodeling in intrahepatic cholangiocarcinomas. ", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ng.2813", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2440141", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2688931", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438813", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2438791", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2412452", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2478763", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2634325", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1103138", 
        "issn": [
          "1061-4036", 
          "1546-1718"
        ], 
        "name": "Nature Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "12", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "45"
      }
    ], 
    "name": "Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas", 
    "pagination": "1470-1473", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "ec7f7b0f7d46152cb715bced2fc58458e085247097bffc9e5cacc5821d7f605c"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "24185509"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9216904"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ng.2813"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1049645772"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ng.2813", 
      "https://app.dimensions.ai/details/publication/pub.1049645772"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-11T13:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000371_0000000371/records_130792_00000004.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ng/journal/v45/n12/full/ng.2813.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.2813'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.2813'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.2813'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.2813'


 

This table displays all metadata directly associated to this object as RDF triples.

500 TRIPLES      21 PREDICATES      67 URIs      38 LITERALS      26 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ng.2813 schema:about N18feb40907e74207ac9708bb1ce6a9f9
2 N28e1b88586ff49b581c6f219a7347c59
3 N2a0b2273b4db4dd296138c95ab6921c8
4 N2f86e5c053d141a9abb71dc495408a96
5 N3f7555769f824cacb0361f4259b195cb
6 N61852a094bbd4177a9d7d34a07bf70da
7 N6f0d982c61a141c28f74a280dbd49fc4
8 N988fc3e618574599a362ca672028c886
9 Na367493ba17b4403b20578c2d3e89ca7
10 Na6486a3c2663419c87508785babee237
11 Nb0f2d8ab5fa54818bb32526f15bcdab3
12 Nb11682d971a44148b16533b5b6245c9d
13 Nd6cfc140d47d4d858265e6e006e53c79
14 Ne5be844d828d48f9b94c9066fca497b5
15 Ne7bfdc8b37a948949e386bce5053f556
16 Neb1c10fca1584a7ab72154bab266f444
17 Nf508bc65d56642afa3d4f8532afa6ab3
18 anzsrc-for:06
19 anzsrc-for:0604
20 schema:author Nca84ba3c6d4d4c748e94c549d76f4a4c
21 schema:citation sg:pub.10.1007/s00268-004-7447-8
22 sg:pub.10.1038/nature09208
23 sg:pub.10.1038/nature09639
24 sg:pub.10.1038/ng.2273
25 sg:pub.10.1038/nrgastro.2011.131
26 sg:pub.10.1038/onc.2012.315
27 sg:pub.10.1038/sj.onc.1210529
28 sg:pub.10.1097/01.mp.0000062656.60581.aa
29 sg:pub.10.2165/11315680-000000000-00000
30 https://app.dimensions.ai/details/publication/pub.1074763329
31 https://doi.org/10.1002/humu.21633
32 https://doi.org/10.1002/path.1139
33 https://doi.org/10.1016/j.biopha.2010.06.009
34 https://doi.org/10.1016/j.humpath.2012.11.006
35 https://doi.org/10.1053/j.gastro.2009.02.038
36 https://doi.org/10.1056/nejmoa0808710
37 https://doi.org/10.1097/pat.0b013e32835d0efb
38 https://doi.org/10.1126/science.1133427
39 https://doi.org/10.1158/2159-8290.cd-13-0050
40 https://doi.org/10.1634/theoncologist.2011-0386
41 https://doi.org/10.2466/pr0.95.2.449-458
42 schema:datePublished 2013-12
43 schema:datePublishedReg 2013-12-01
44 schema:description Through exomic sequencing of 32 intrahepatic cholangiocarcinomas, we discovered frequent inactivating mutations in multiple chromatin-remodeling genes (including BAP1, ARID1A and PBRM1), and mutation in one of these genes occurred in almost half of the carcinomas sequenced. We also identified frequent mutations at previously reported hotspots in the IDH1 and IDH2 genes encoding metabolic enzymes in intrahepatic cholangiocarcinomas. In contrast, TP53 was the most frequently altered gene in a series of nine gallbladder carcinomas. These discoveries highlight the key role of dysregulated chromatin remodeling in intrahepatic cholangiocarcinomas.
45 schema:genre research_article
46 schema:inLanguage en
47 schema:isAccessibleForFree true
48 schema:isPartOf N7558c9cf5f874b88b9448b892c3805b8
49 Ne67600efa88d4485bb3b34a841517d90
50 sg:journal.1103138
51 schema:name Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas
52 schema:pagination 1470-1473
53 schema:productId N3c82da7f15ff4167a859ff81d908afa6
54 N3fb6206eb8c84825b2b7ce21c6c2c379
55 Nbc5a724572c546a2aaefcf809c56b65b
56 Nbf868b356fbe4dea835669e2810ae8f9
57 Nc5ecf7d8f01b4b7e95138bd7c92dd94a
58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049645772
59 https://doi.org/10.1038/ng.2813
60 schema:sdDatePublished 2019-04-11T13:47
61 schema:sdLicense https://scigraph.springernature.com/explorer/license/
62 schema:sdPublisher Nc524990ae4b54bd79f1a706d84205acf
63 schema:url http://www.nature.com/ng/journal/v45/n12/full/ng.2813.html
64 sgo:license sg:explorer/license/
65 sgo:sdDataset articles
66 rdf:type schema:ScholarlyArticle
67 N022e56e666cc486c8c0e20245e2da490 rdf:first sg:person.010340527017.07
68 rdf:rest Nc668a6fc80a04c0eb0c204208989052a
69 N0732fa681ad54e57be5b9233ae510cdf rdf:first sg:person.0714157340.24
70 rdf:rest N65b3983005884cd2b050557e5ca26519
71 N092e15f58c914445b0b67c42d5a53879 rdf:first sg:person.013623242142.34
72 rdf:rest N94bd4880f9634bde8ca28b33e282687b
73 N18feb40907e74207ac9708bb1ce6a9f9 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
74 schema:name Bile Ducts, Intrahepatic
75 rdf:type schema:DefinedTerm
76 N20fceca468124802a1976b543b50321c rdf:first sg:person.01213310466.21
77 rdf:rest N48954b9417fb44b3a647920e21bc60a9
78 N214f700806d440f2a2110e924b86b3e8 rdf:first sg:person.01162514032.19
79 rdf:rest Nb13afaa3a4714e7eb78387e5e107e7e8
80 N28e1b88586ff49b581c6f219a7347c59 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
81 schema:name Mutation, Missense
82 rdf:type schema:DefinedTerm
83 N2a0b2273b4db4dd296138c95ab6921c8 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
84 schema:name Female
85 rdf:type schema:DefinedTerm
86 N2bb403d85f964affaca4cad3107a2c6d schema:affiliation https://www.grid.ac/institutes/grid.51462.34
87 schema:familyName Jarnagin
88 schema:givenName William
89 rdf:type schema:Person
90 N2f86e5c053d141a9abb71dc495408a96 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
91 schema:name Tumor Suppressor Proteins
92 rdf:type schema:DefinedTerm
93 N30a576f480a14d7d9351226484a44fd4 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
94 schema:familyName Wood
95 schema:givenName Laura D
96 rdf:type schema:Person
97 N381009bb06ab484b96968a5ad7c10926 rdf:first sg:person.0660433203.71
98 rdf:rest N0732fa681ad54e57be5b9233ae510cdf
99 N3c82da7f15ff4167a859ff81d908afa6 schema:name readcube_id
100 schema:value ec7f7b0f7d46152cb715bced2fc58458e085247097bffc9e5cacc5821d7f605c
101 rdf:type schema:PropertyValue
102 N3f68773bb3c5449c9d082daf008ea8c4 rdf:first N2bb403d85f964affaca4cad3107a2c6d
103 rdf:rest Nd0650fcf59c240128ea197a78764105a
104 N3f7555769f824cacb0361f4259b195cb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
105 schema:name Male
106 rdf:type schema:DefinedTerm
107 N3fb6206eb8c84825b2b7ce21c6c2c379 schema:name pubmed_id
108 schema:value 24185509
109 rdf:type schema:PropertyValue
110 N44365d71e6044e11801c42ed06c250a6 rdf:first sg:person.0651153564.24
111 rdf:rest N9fe3565711364141b53e71c9a322dd6a
112 N48954b9417fb44b3a647920e21bc60a9 rdf:first sg:person.01171343404.33
113 rdf:rest Nf55c04788e3341ee939191a69ce226a4
114 N52219cb8af5c4cfb82586a6ee59b34ea rdf:first sg:person.012622657362.12
115 rdf:rest N3f68773bb3c5449c9d082daf008ea8c4
116 N5c3526399aa04fd7bc06cce55149d8ae rdf:first sg:person.0625050266.98
117 rdf:rest Na3bd146352944686a3ad04182424bdc5
118 N61852a094bbd4177a9d7d34a07bf70da schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
119 schema:name Cholangiocarcinoma
120 rdf:type schema:DefinedTerm
121 N65b3983005884cd2b050557e5ca26519 rdf:first sg:person.0632617652.16
122 rdf:rest Nc1a954ba634f43b0829554a722033890
123 N67c7d91d20de488e8c2a899cc09ea97b rdf:first Nd770fc29da1e4a6fa4e0b62f9a7d26ad
124 rdf:rest N20fceca468124802a1976b543b50321c
125 N6b7c5ad11c704d47a1c9cc841c44f943 rdf:first sg:person.0620255165.48
126 rdf:rest N67c7d91d20de488e8c2a899cc09ea97b
127 N6f0d982c61a141c28f74a280dbd49fc4 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
128 schema:name Liver Neoplasms
129 rdf:type schema:DefinedTerm
130 N738d6c212f7b4dcc90626771b2eea4b2 rdf:first sg:person.01102666143.51
131 rdf:rest Ne5d9f2381fd24b38bae448a21f44f2e5
132 N7558c9cf5f874b88b9448b892c3805b8 schema:issueNumber 12
133 rdf:type schema:PublicationIssue
134 N7da737eb094d4a61bd583ab22f50bafd rdf:first sg:person.01326154272.37
135 rdf:rest Na266bf79571b46418039a4f84348f1f4
136 N826ef223856f414fadac0e10c96cf34c rdf:first sg:person.01122564664.32
137 rdf:rest Ncbc9c9161d1c44e1ac750e792783cb51
138 N83054f3cd3e541a0b4387678d2d5e6c7 rdf:first sg:person.0721627074.41
139 rdf:rest Nd1991ffe28d14f919e03a0ac3396af09
140 N94bd4880f9634bde8ca28b33e282687b rdf:first N30a576f480a14d7d9351226484a44fd4
141 rdf:rest rdf:nil
142 N988fc3e618574599a362ca672028c886 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
143 schema:name Sequence Analysis, DNA
144 rdf:type schema:DefinedTerm
145 N9e9bb90b2bd34013b1c7c96cae194503 rdf:first sg:person.07702206317.64
146 rdf:rest N381009bb06ab484b96968a5ad7c10926
147 N9fe3565711364141b53e71c9a322dd6a rdf:first sg:person.010354303077.37
148 rdf:rest Nef6794914e8b4f14975680f7d889abc3
149 Na266bf79571b46418039a4f84348f1f4 rdf:first sg:person.016670317257.91
150 rdf:rest N9e9bb90b2bd34013b1c7c96cae194503
151 Na367493ba17b4403b20578c2d3e89ca7 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
152 schema:name Humans
153 rdf:type schema:DefinedTerm
154 Na3bd146352944686a3ad04182424bdc5 rdf:first sg:person.01050022401.71
155 rdf:rest N826ef223856f414fadac0e10c96cf34c
156 Na6486a3c2663419c87508785babee237 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
157 schema:name Nuclear Proteins
158 rdf:type schema:DefinedTerm
159 Nab221bb06a9f496eb156b7656eda7e1c rdf:first sg:person.01174147316.99
160 rdf:rest N6b7c5ad11c704d47a1c9cc841c44f943
161 Nb0f2d8ab5fa54818bb32526f15bcdab3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
162 schema:name Transcription Factors
163 rdf:type schema:DefinedTerm
164 Nb11682d971a44148b16533b5b6245c9d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
165 schema:name Ubiquitin Thiolesterase
166 rdf:type schema:DefinedTerm
167 Nb13afaa3a4714e7eb78387e5e107e7e8 rdf:first sg:person.0632553362.25
168 rdf:rest N5c3526399aa04fd7bc06cce55149d8ae
169 Nbc5a724572c546a2aaefcf809c56b65b schema:name doi
170 schema:value 10.1038/ng.2813
171 rdf:type schema:PropertyValue
172 Nbd297a64315c41abaf1ffc1d78ed06d9 schema:affiliation https://www.grid.ac/institutes/grid.51462.34
173 schema:familyName Klimstra
174 schema:givenName David
175 rdf:type schema:Person
176 Nbf868b356fbe4dea835669e2810ae8f9 schema:name nlm_unique_id
177 schema:value 9216904
178 rdf:type schema:PropertyValue
179 Nc1a954ba634f43b0829554a722033890 rdf:first sg:person.01215230032.09
180 rdf:rest N738d6c212f7b4dcc90626771b2eea4b2
181 Nc2e6f8d73b3742b480ea55dcc8a9df09 rdf:first sg:person.011173760757.54
182 rdf:rest Ncb1fc30cb4b8495fa851246b275d5554
183 Nc524990ae4b54bd79f1a706d84205acf schema:name Springer Nature - SN SciGraph project
184 rdf:type schema:Organization
185 Nc5ecf7d8f01b4b7e95138bd7c92dd94a schema:name dimensions_id
186 schema:value pub.1049645772
187 rdf:type schema:PropertyValue
188 Nc668a6fc80a04c0eb0c204208989052a rdf:first sg:person.014561616077.23
189 rdf:rest N7da737eb094d4a61bd583ab22f50bafd
190 Nca84ba3c6d4d4c748e94c549d76f4a4c rdf:first sg:person.0631663776.31
191 rdf:rest N83054f3cd3e541a0b4387678d2d5e6c7
192 Ncb1fc30cb4b8495fa851246b275d5554 rdf:first sg:person.0620642630.54
193 rdf:rest N092e15f58c914445b0b67c42d5a53879
194 Ncbc9c9161d1c44e1ac750e792783cb51 rdf:first sg:person.0660154036.65
195 rdf:rest N52219cb8af5c4cfb82586a6ee59b34ea
196 Nd0650fcf59c240128ea197a78764105a rdf:first Nbd297a64315c41abaf1ffc1d78ed06d9
197 rdf:rest N44365d71e6044e11801c42ed06c250a6
198 Nd1991ffe28d14f919e03a0ac3396af09 rdf:first sg:person.01210010423.38
199 rdf:rest Nab221bb06a9f496eb156b7656eda7e1c
200 Nd6cfc140d47d4d858265e6e006e53c79 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
201 schema:name Cohort Studies
202 rdf:type schema:DefinedTerm
203 Nd770fc29da1e4a6fa4e0b62f9a7d26ad schema:affiliation https://www.grid.ac/institutes/grid.414467.4
204 schema:familyName Lucas
205 schema:givenName Donald J
206 rdf:type schema:Person
207 Ne5be844d828d48f9b94c9066fca497b5 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
208 schema:name Survival Analysis
209 rdf:type schema:DefinedTerm
210 Ne5d9f2381fd24b38bae448a21f44f2e5 rdf:first sg:person.0602412452.71
211 rdf:rest N214f700806d440f2a2110e924b86b3e8
212 Ne67600efa88d4485bb3b34a841517d90 schema:volumeNumber 45
213 rdf:type schema:PublicationVolume
214 Ne7bfdc8b37a948949e386bce5053f556 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
215 schema:name Bile Duct Neoplasms
216 rdf:type schema:DefinedTerm
217 Neb1c10fca1584a7ab72154bab266f444 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
218 schema:name Exome
219 rdf:type schema:DefinedTerm
220 Nef6794914e8b4f14975680f7d889abc3 rdf:first sg:person.07624111077.08
221 rdf:rest Nc2e6f8d73b3742b480ea55dcc8a9df09
222 Nf508bc65d56642afa3d4f8532afa6ab3 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
223 schema:name Gene Frequency
224 rdf:type schema:DefinedTerm
225 Nf55c04788e3341ee939191a69ce226a4 rdf:first sg:person.01246576774.91
226 rdf:rest N022e56e666cc486c8c0e20245e2da490
227 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
228 schema:name Biological Sciences
229 rdf:type schema:DefinedTerm
230 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
231 schema:name Genetics
232 rdf:type schema:DefinedTerm
233 sg:grant.2412452 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
234 rdf:type schema:MonetaryGrant
235 sg:grant.2438791 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
236 rdf:type schema:MonetaryGrant
237 sg:grant.2438813 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
238 rdf:type schema:MonetaryGrant
239 sg:grant.2440141 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
240 rdf:type schema:MonetaryGrant
241 sg:grant.2478763 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
242 rdf:type schema:MonetaryGrant
243 sg:grant.2634325 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
244 rdf:type schema:MonetaryGrant
245 sg:grant.2688931 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.2813
246 rdf:type schema:MonetaryGrant
247 sg:journal.1103138 schema:issn 1061-4036
248 1546-1718
249 schema:name Nature Genetics
250 rdf:type schema:Periodical
251 sg:person.010340527017.07 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
252 schema:familyName Argani
253 schema:givenName Pedram
254 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010340527017.07
255 rdf:type schema:Person
256 sg:person.010354303077.37 schema:affiliation https://www.grid.ac/institutes/grid.469474.c
257 schema:familyName Velculescu
258 schema:givenName Victor E
259 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010354303077.37
260 rdf:type schema:Person
261 sg:person.01050022401.71 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
262 schema:familyName Guglielmi
263 schema:givenName Alfredo
264 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01050022401.71
265 rdf:type schema:Person
266 sg:person.01102666143.51 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
267 schema:familyName Simbolo
268 schema:givenName Michele
269 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01102666143.51
270 rdf:type schema:Person
271 sg:person.011173760757.54 schema:affiliation https://www.grid.ac/institutes/grid.469474.c
272 schema:familyName Vogelstein
273 schema:givenName Bert
274 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.011173760757.54
275 rdf:type schema:Person
276 sg:person.01122564664.32 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
277 schema:familyName Tortora
278 schema:givenName Giampaolo
279 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01122564664.32
280 rdf:type schema:Person
281 sg:person.01162514032.19 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
282 schema:familyName Capelli
283 schema:givenName Paola
284 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01162514032.19
285 rdf:type schema:Person
286 sg:person.01171343404.33 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
287 schema:familyName Guthrie
288 schema:givenName Violeta Beleva
289 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01171343404.33
290 rdf:type schema:Person
291 sg:person.01174147316.99 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
292 schema:familyName Selaru
293 schema:givenName Florin M
294 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01174147316.99
295 rdf:type schema:Person
296 sg:person.01210010423.38 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
297 schema:familyName Anders
298 schema:givenName Robert A
299 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01210010423.38
300 rdf:type schema:Person
301 sg:person.01213310466.21 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
302 schema:familyName Niknafs
303 schema:givenName Noushin
304 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01213310466.21
305 rdf:type schema:Person
306 sg:person.01215230032.09 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
307 schema:familyName Fassan
308 schema:givenName Matteo
309 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01215230032.09
310 rdf:type schema:Person
311 sg:person.01246576774.91 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
312 schema:familyName Maitra
313 schema:givenName Anirban
314 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01246576774.91
315 rdf:type schema:Person
316 sg:person.012622657362.12 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
317 schema:familyName Scarpa
318 schema:givenName Aldo
319 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012622657362.12
320 rdf:type schema:Person
321 sg:person.01326154272.37 schema:affiliation https://www.grid.ac/institutes/grid.412163.3
322 schema:familyName Roa
323 schema:givenName Juan Carlos
324 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01326154272.37
325 rdf:type schema:Person
326 sg:person.013623242142.34 schema:affiliation https://www.grid.ac/institutes/grid.469474.c
327 schema:familyName Papadopoulos
328 schema:givenName Nickolas
329 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013623242142.34
330 rdf:type schema:Person
331 sg:person.014561616077.23 schema:affiliation https://www.grid.ac/institutes/grid.7692.a
332 schema:familyName Offerhaus
333 schema:givenName G Johan A
334 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014561616077.23
335 rdf:type schema:Person
336 sg:person.016670317257.91 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
337 schema:familyName Roberts
338 schema:givenName Lewis R
339 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.016670317257.91
340 rdf:type schema:Person
341 sg:person.0602412452.71 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
342 schema:familyName Mafficini
343 schema:givenName Andrea
344 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602412452.71
345 rdf:type schema:Person
346 sg:person.0620255165.48 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
347 schema:familyName Streppel
348 schema:givenName Mirte M
349 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620255165.48
350 rdf:type schema:Person
351 sg:person.0620642630.54 schema:affiliation https://www.grid.ac/institutes/grid.469474.c
352 schema:familyName Kinzler
353 schema:givenName Kenneth W
354 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0620642630.54
355 rdf:type schema:Person
356 sg:person.0625050266.98 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
357 schema:familyName Ruzzenente
358 schema:givenName Andrea
359 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0625050266.98
360 rdf:type schema:Person
361 sg:person.0631663776.31 schema:affiliation https://www.grid.ac/institutes/grid.469474.c
362 schema:familyName Jiao
363 schema:givenName Yuchen
364 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0631663776.31
365 rdf:type schema:Person
366 sg:person.0632553362.25 schema:affiliation https://www.grid.ac/institutes/grid.5611.3
367 schema:familyName Lawlor
368 schema:givenName Rita T
369 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632553362.25
370 rdf:type schema:Person
371 sg:person.0632617652.16 schema:affiliation https://www.grid.ac/institutes/grid.415180.9
372 schema:familyName Dima
373 schema:givenName Simona
374 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0632617652.16
375 rdf:type schema:Person
376 sg:person.0651153564.24 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
377 schema:familyName Karchin
378 schema:givenName Rachel
379 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0651153564.24
380 rdf:type schema:Person
381 sg:person.0660154036.65 schema:affiliation https://www.grid.ac/institutes/grid.417893.0
382 schema:familyName de Braud
383 schema:givenName Filippo
384 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660154036.65
385 rdf:type schema:Person
386 sg:person.0660433203.71 schema:affiliation https://www.grid.ac/institutes/grid.415180.9
387 schema:familyName Popescu
388 schema:givenName Irinel
389 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0660433203.71
390 rdf:type schema:Person
391 sg:person.0714157340.24 schema:affiliation https://www.grid.ac/institutes/grid.415180.9
392 schema:familyName Alexandrescu
393 schema:givenName Sorin T
394 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0714157340.24
395 rdf:type schema:Person
396 sg:person.0721627074.41 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
397 schema:familyName Pawlik
398 schema:givenName Timothy M
399 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0721627074.41
400 rdf:type schema:Person
401 sg:person.07624111077.08 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
402 schema:familyName Hruban
403 schema:givenName Ralph H
404 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07624111077.08
405 rdf:type schema:Person
406 sg:person.07702206317.64 schema:affiliation https://www.grid.ac/institutes/grid.66875.3a
407 schema:familyName Gores
408 schema:givenName Gregory J
409 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.07702206317.64
410 rdf:type schema:Person
411 sg:pub.10.1007/s00268-004-7447-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051594530
412 https://doi.org/10.1007/s00268-004-7447-8
413 rdf:type schema:CreativeWork
414 sg:pub.10.1038/nature09208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048324405
415 https://doi.org/10.1038/nature09208
416 rdf:type schema:CreativeWork
417 sg:pub.10.1038/nature09639 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009539954
418 https://doi.org/10.1038/nature09639
419 rdf:type schema:CreativeWork
420 sg:pub.10.1038/ng.2273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053156141
421 https://doi.org/10.1038/ng.2273
422 rdf:type schema:CreativeWork
423 sg:pub.10.1038/nrgastro.2011.131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037668976
424 https://doi.org/10.1038/nrgastro.2011.131
425 rdf:type schema:CreativeWork
426 sg:pub.10.1038/onc.2012.315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046269452
427 https://doi.org/10.1038/onc.2012.315
428 rdf:type schema:CreativeWork
429 sg:pub.10.1038/sj.onc.1210529 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000136651
430 https://doi.org/10.1038/sj.onc.1210529
431 rdf:type schema:CreativeWork
432 sg:pub.10.1097/01.mp.0000062656.60581.aa schema:sameAs https://app.dimensions.ai/details/publication/pub.1052182241
433 https://doi.org/10.1097/01.mp.0000062656.60581.aa
434 rdf:type schema:CreativeWork
435 sg:pub.10.2165/11315680-000000000-00000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014688288
436 https://doi.org/10.2165/11315680-000000000-00000
437 rdf:type schema:CreativeWork
438 https://app.dimensions.ai/details/publication/pub.1074763329 schema:CreativeWork
439 https://doi.org/10.1002/humu.21633 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042168641
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1002/path.1139 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017581467
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1016/j.biopha.2010.06.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004851269
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1016/j.humpath.2012.11.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017260131
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1053/j.gastro.2009.02.038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013903203
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1056/nejmoa0808710 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035319148
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1097/pat.0b013e32835d0efb schema:sameAs https://app.dimensions.ai/details/publication/pub.1031538966
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1126/science.1133427 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000786924
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1158/2159-8290.cd-13-0050 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052822978
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1634/theoncologist.2011-0386 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008469500
458 rdf:type schema:CreativeWork
459 https://doi.org/10.2466/pr0.95.2.449-458 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070823125
460 rdf:type schema:CreativeWork
461 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
462 schema:name Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
463 Department of Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, Maryland, USA.
464 Department of Pathology, Johns Hopkins University, Baltimore, Maryland, USA.
465 Department of Surgery, Johns Hopkins University, Baltimore, Maryland, USA.
466 Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
467 rdf:type schema:Organization
468 https://www.grid.ac/institutes/grid.412163.3 schema:alternateName University of La Frontera
469 schema:name Department of Pathology, Universidad de La Frontera, Temuco, Chile.
470 rdf:type schema:Organization
471 https://www.grid.ac/institutes/grid.414467.4 schema:alternateName Walter Reed National Military Medical Center
472 schema:name Department of Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
473 rdf:type schema:Organization
474 https://www.grid.ac/institutes/grid.415180.9 schema:alternateName Institutul Clinic Fundeni
475 schema:name Dan Setlacec Center of General Surgery and Liver Transplantation, Fundeni Clinical Institute, Bucharest, Romania.
476 rdf:type schema:Organization
477 https://www.grid.ac/institutes/grid.417893.0 schema:alternateName Istituto Nazionale dei Tumori
478 schema:name Medical Oncology Unit 1, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy.
479 rdf:type schema:Organization
480 https://www.grid.ac/institutes/grid.469474.c schema:alternateName Johns Hopkins Medicine
481 schema:name Howard Hughes Medical Institute, Johns Hopkins University, Baltimore, Maryland, USA.
482 Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland, USA.
483 The Ludwig Center, Johns Hopkins University, Baltimore, Maryland, USA.
484 rdf:type schema:Organization
485 https://www.grid.ac/institutes/grid.51462.34 schema:alternateName Memorial Sloan Kettering Cancer Center
486 schema:name Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
487 Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
488 rdf:type schema:Organization
489 https://www.grid.ac/institutes/grid.5611.3 schema:alternateName University of Verona
490 schema:name Applied Research on Cancer Network, Miriam Cherubini Research Centre, University of Verona, Verona, Italy.
491 Department of Medicine, Medical Oncology Unit, University of Verona, Verona, Italy.
492 Department of Pathology and Diagnostics, University of Verona, Verona, Italy.
493 Department of Surgery, University of Verona, Verona, Italy.
494 rdf:type schema:Organization
495 https://www.grid.ac/institutes/grid.66875.3a schema:alternateName Mayo Clinic
496 schema:name Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA.
497 rdf:type schema:Organization
498 https://www.grid.ac/institutes/grid.7692.a schema:alternateName University Medical Center Utrecht
499 schema:name Department of Pathology, University Medical Center, Utrecht, The Netherlands.
500 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...