MYH9 is associated with nondiabetic end-stage renal disease in African Americans View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-10

AUTHORS

W H Linda Kao, Michael J Klag, Lucy A Meoni, David Reich, Yvette Berthier-Schaad, Man Li, Josef Coresh, Nick Patterson, Arti Tandon, Neil R Powe, Nancy E Fink, John H Sadler, Matthew R Weir, Hanna E Abboud, Sharon G Adler, Jasmin Divers, Sudha K Iyengar, Barry I Freedman, Paul L Kimmel, William C Knowler, Orly F Kohn, Kristopher Kramp, David J Leehey, Susanne B Nicholas, Madeleine V Pahl, Jeffrey R Schelling, John R Sedor, Denyse Thornley-Brown, Cheryl A Winkler, Michael W Smith, Rulan S Parekh

ABSTRACT

As end-stage renal disease (ESRD) has a four times higher incidence in African Americans compared to European Americans, we hypothesized that susceptibility alleles for ESRD have a higher frequency in the West African than the European gene pool. We carried out a genome-wide admixture scan in 1,372 ESRD cases and 806 controls and found a highly significant association between excess African ancestry and nondiabetic ESRD (lod score = 5.70) but not diabetic ESRD (lod = 0.47) on chromosome 22q12. Each copy of the European ancestral allele conferred a relative risk of 0.50 (95% CI = 0.39-0.63) compared to African ancestry. Multiple common SNPs (allele frequencies ranging from 0.2 to 0.6) in the gene encoding nonmuscle myosin heavy chain type II isoform A (MYH9) were associated with two to four times greater risk of nondiabetic ESRD and accounted for a large proportion of the excess risk of ESRD observed in African compared to European Americans. More... »

PAGES

1185-1192

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng.232

DOI

http://dx.doi.org/10.1038/ng.232

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1008005765

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/18794854


Indexing Status Check whether this publication has been indexed by Scopus and Web Of Science using the SN Indexing Status Tool
Incoming Citations Browse incoming citations for this publication using opencitations.net

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0604", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Genetics", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "name": "Biological Sciences", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "African Americans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Case-Control Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosome Mapping", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Chromosomes, Human, Pair 22", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Cohort Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "DNA Primers", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Diabetes Mellitus", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "European Continental Ancestry Group", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Female", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Linkage", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genetic Predisposition to Disease", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Genome, Human", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Glomerulosclerosis, Focal Segmental", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Haplotypes", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Humans", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Kidney Failure, Chronic", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Lod Score", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Male", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Middle Aged", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Molecular Motor Proteins", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Myosin Heavy Chains", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Polymorphism, Single Nucleotide", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Prospective Studies", 
        "type": "DefinedTerm"
      }, 
      {
        "inDefinedTermSet": "https://www.nlm.nih.gov/mesh/", 
        "name": "Risk Factors", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "affiliation": {
          "alternateName": "Johns Hopkins University", 
          "id": "https://www.grid.ac/institutes/grid.21107.35", 
          "name": [
            "Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA. wkao@jhsph.edu"
          ], 
          "type": "Organization"
        }, 
        "familyName": "Kao", 
        "givenName": "W H Linda", 
        "id": "sg:person.010012617237.52", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012617237.52"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Klag", 
        "givenName": "Michael J", 
        "id": "sg:person.015243204277.40", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015243204277.40"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Meoni", 
        "givenName": "Lucy A", 
        "id": "sg:person.01314463305.15", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314463305.15"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Reich", 
        "givenName": "David", 
        "type": "Person"
      }, 
      {
        "familyName": "Berthier-Schaad", 
        "givenName": "Yvette", 
        "id": "sg:person.01052515715.67", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052515715.67"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Li", 
        "givenName": "Man", 
        "type": "Person"
      }, 
      {
        "familyName": "Coresh", 
        "givenName": "Josef", 
        "id": "sg:person.012700421217.04", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012700421217.04"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Patterson", 
        "givenName": "Nick", 
        "type": "Person"
      }, 
      {
        "familyName": "Tandon", 
        "givenName": "Arti", 
        "type": "Person"
      }, 
      {
        "familyName": "Powe", 
        "givenName": "Neil R", 
        "id": "sg:person.01114375365.22", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114375365.22"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Fink", 
        "givenName": "Nancy E", 
        "type": "Person"
      }, 
      {
        "familyName": "Sadler", 
        "givenName": "John H", 
        "type": "Person"
      }, 
      {
        "familyName": "Weir", 
        "givenName": "Matthew R", 
        "type": "Person"
      }, 
      {
        "familyName": "Abboud", 
        "givenName": "Hanna E", 
        "type": "Person"
      }, 
      {
        "familyName": "Adler", 
        "givenName": "Sharon G", 
        "type": "Person"
      }, 
      {
        "familyName": "Divers", 
        "givenName": "Jasmin", 
        "type": "Person"
      }, 
      {
        "familyName": "Iyengar", 
        "givenName": "Sudha K", 
        "id": "sg:person.01207503671.81", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207503671.81"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Freedman", 
        "givenName": "Barry I", 
        "type": "Person"
      }, 
      {
        "familyName": "Kimmel", 
        "givenName": "Paul L", 
        "type": "Person"
      }, 
      {
        "familyName": "Knowler", 
        "givenName": "William C", 
        "id": "sg:person.014046535652.10", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014046535652.10"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kohn", 
        "givenName": "Orly F", 
        "id": "sg:person.0602545663.05", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602545663.05"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Kramp", 
        "givenName": "Kristopher", 
        "id": "sg:person.01045313501.99", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045313501.99"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Leehey", 
        "givenName": "David J", 
        "type": "Person"
      }, 
      {
        "familyName": "Nicholas", 
        "givenName": "Susanne B", 
        "type": "Person"
      }, 
      {
        "familyName": "Pahl", 
        "givenName": "Madeleine V", 
        "id": "sg:person.013117314214.24", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013117314214.24"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Schelling", 
        "givenName": "Jeffrey R", 
        "id": "sg:person.013572122437.31", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013572122437.31"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Sedor", 
        "givenName": "John R", 
        "type": "Person"
      }, 
      {
        "familyName": "Thornley-Brown", 
        "givenName": "Denyse", 
        "id": "sg:person.0735016154.25", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735016154.25"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Winkler", 
        "givenName": "Cheryl A", 
        "id": "sg:person.010724122777.86", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010724122777.86"
        ], 
        "type": "Person"
      }, 
      {
        "familyName": "Smith", 
        "givenName": "Michael W", 
        "type": "Person"
      }, 
      {
        "familyName": "Parekh", 
        "givenName": "Rulan S", 
        "id": "sg:person.0637647532.17", 
        "sameAs": [
          "https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637647532.17"
        ], 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1016/j.jdiacomp.2003.12.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003277453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0272-6386(12)80266-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003501598"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1600-0609.2008.01046.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009334668"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-1119(02)00455-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011847147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012092299", 
          "https://doi.org/10.1038/nrg1657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012092299", 
          "https://doi.org/10.1038/nrg1657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrg1657", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012092299", 
          "https://doi.org/10.1038/nrg1657"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1469-1809.2000.6420171.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017036179"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng2015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018455308", 
          "https://doi.org/10.1038/ng2015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng2015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018455308", 
          "https://doi.org/10.1038/ng2015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng.226", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022042808", 
          "https://doi.org/10.1038/ng.226"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ajh.21102", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022761202"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1105436", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027070431"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.288.19.2421", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027820125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1525-139x.1996.tb00890.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029646602"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030469947", 
          "https://doi.org/10.1038/ng1646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030469947", 
          "https://doi.org/10.1038/ng1646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ng1646", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030469947", 
          "https://doi.org/10.1038/ng1646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00439-001-0659-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033372905", 
          "https://doi.org/10.1007/s00439-001-0659-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00439-001-0659-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033372905", 
          "https://doi.org/10.1007/s00439-001-0659-1"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajhg.2007.09.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033742684"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/79069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034180464", 
          "https://doi.org/10.1038/79069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/79069", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034180464", 
          "https://doi.org/10.1038/79069"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci27699", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038453425"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.012025199", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044815609"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature06258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051134045", 
          "https://doi.org/10.1038/nature06258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.23.9119", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053426991"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/archinte.155.11.1201", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054114594"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1001/jama.277.16.1293", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054160859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004399900132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054516725", 
          "https://doi.org/10.1007/s004399900132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004399900132", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054516725", 
          "https://doi.org/10.1007/s004399900132"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.amjhyper.2004.02.019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054726013"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/301908", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058609505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/420856", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058711796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/420871", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058711806"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/426405", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1058714689"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000026493.18542.6a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060318865"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000070078.66465.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000070078.66465.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000070078.66465.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000070078.66465.55", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000135972.13396.6f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000135972.13396.6f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000135972.13396.6f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.asn.0000135972.13396.6f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060319690"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/ijmm.17.5.729", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071506284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1075304464", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1082576388", 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://app.dimensions.ai/details/publication/pub.1083283698", 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2008-10", 
    "datePublishedReg": "2008-10-01", 
    "description": "As end-stage renal disease (ESRD) has a four times higher incidence in African Americans compared to European Americans, we hypothesized that susceptibility alleles for ESRD have a higher frequency in the West African than the European gene pool. We carried out a genome-wide admixture scan in 1,372 ESRD cases and 806 controls and found a highly significant association between excess African ancestry and nondiabetic ESRD (lod score = 5.70) but not diabetic ESRD (lod = 0.47) on chromosome 22q12. Each copy of the European ancestral allele conferred a relative risk of 0.50 (95% CI = 0.39-0.63) compared to African ancestry. Multiple common SNPs (allele frequencies ranging from 0.2 to 0.6) in the gene encoding nonmuscle myosin heavy chain type II isoform A (MYH9) were associated with two to four times greater risk of nondiabetic ESRD and accounted for a large proportion of the excess risk of ESRD observed in African compared to European Americans.", 
    "genre": "research_article", 
    "id": "sg:pub.10.1038/ng.232", 
    "inLanguage": [
      "en"
    ], 
    "isAccessibleForFree": true, 
    "isFundedItemOf": [
      {
        "id": "sg:grant.2424026", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2423985", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2723619", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2498794", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2536957", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.5246872", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424008", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2725006", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2690161", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424041", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2683090", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2689914", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2497337", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2724979", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2544619", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2404053", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2689909", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2723637", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2424016", 
        "type": "MonetaryGrant"
      }, 
      {
        "id": "sg:grant.2498315", 
        "type": "MonetaryGrant"
      }
    ], 
    "isPartOf": [
      {
        "id": "sg:journal.1103138", 
        "issn": [
          "1061-4036", 
          "1546-1718"
        ], 
        "name": "Nature Genetics", 
        "type": "Periodical"
      }, 
      {
        "issueNumber": "10", 
        "type": "PublicationIssue"
      }, 
      {
        "type": "PublicationVolume", 
        "volumeNumber": "40"
      }
    ], 
    "name": "MYH9 is associated with nondiabetic end-stage renal disease in African Americans", 
    "pagination": "1185-1192", 
    "productId": [
      {
        "name": "readcube_id", 
        "type": "PropertyValue", 
        "value": [
          "2623f6caf5141b35ac62a1e8dd46b8b0021a041c083e5b7de5f31f098b3edad4"
        ]
      }, 
      {
        "name": "pubmed_id", 
        "type": "PropertyValue", 
        "value": [
          "18794854"
        ]
      }, 
      {
        "name": "nlm_unique_id", 
        "type": "PropertyValue", 
        "value": [
          "9216904"
        ]
      }, 
      {
        "name": "doi", 
        "type": "PropertyValue", 
        "value": [
          "10.1038/ng.232"
        ]
      }, 
      {
        "name": "dimensions_id", 
        "type": "PropertyValue", 
        "value": [
          "pub.1008005765"
        ]
      }
    ], 
    "sameAs": [
      "https://doi.org/10.1038/ng.232", 
      "https://app.dimensions.ai/details/publication/pub.1008005765"
    ], 
    "sdDataset": "articles", 
    "sdDatePublished": "2019-04-10T14:47", 
    "sdLicense": "https://scigraph.springernature.com/explorer/license/", 
    "sdPublisher": {
      "name": "Springer Nature - SN SciGraph project", 
      "type": "Organization"
    }, 
    "sdSource": "s3://com-uberresearch-data-dimensions-target-20181106-alternative/cleanup/v134/2549eaecd7973599484d7c17b260dba0a4ecb94b/merge/v9/a6c9fde33151104705d4d7ff012ea9563521a3ce/jats-lookup/v90/0000000001_0000000264/records_8663_00000422.jsonl", 
    "type": "ScholarlyArticle", 
    "url": "http://www.nature.com/ng/journal/v40/n10/full/ng.232.html"
  }
]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/pub.10.1038/ng.232'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/pub.10.1038/ng.232'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/pub.10.1038/ng.232'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/pub.10.1038/ng.232'


 

This table displays all metadata directly associated to this object as RDF triples.

479 TRIPLES      21 PREDICATES      88 URIs      45 LITERALS      33 BLANK NODES

Subject Predicate Object
1 sg:pub.10.1038/ng.232 schema:about N048c827fc0fc42f5a752628f3dbe10e1
2 N279bebf398ac412ab3800cd9b1fd6007
3 N31bf8ebd03c54385b5ec40f095281adb
4 N31d79a5e546c4b2096e01b26985d3501
5 N345d94c2b01941e3a610ee742d292e32
6 N3967e220713143c8986082f62b0cc565
7 N3c2b41aa485e437996ac3ffa0440554f
8 N515dbf498e8343428ef3e7fdf80f2560
9 N604d56c4aa564bb98faa613fe623c26f
10 N62d35e7adb10439baf76a65ae909d4f0
11 N684cc2360a09463983f6a22190632a1a
12 N701b21c8de9c4c7a9b40be6c071e1739
13 N75cb298356484887a6e4abc6d54189e1
14 N76fb44e1dadb4ca0b71905c06001e784
15 N780c9385d61f43159c4e9feebe44a56d
16 N7a90193e412d40c6ba4ab69150810dfd
17 N82f30b855ffd4d1696a10726aa617831
18 N876c42bb776c4d548f815156b68c3e8e
19 N90ed00fb74084660a71fc84992b10230
20 N934f71aecbbc412e830260bb93e7b138
21 Nb6915bd7258d4d1b912d1a4d05e6277a
22 Nd31673e75c7b429d869e89233b43cd0b
23 Nd43588a43f51462db85ae37cec2a659a
24 Ndd51cde42c5846cc86262301b5bb1060
25 anzsrc-for:06
26 anzsrc-for:0604
27 schema:author Ncde77b3e827040d1b2d63cdeb44fb553
28 schema:citation sg:pub.10.1007/s00439-001-0659-1
29 sg:pub.10.1007/s004399900132
30 sg:pub.10.1038/79069
31 sg:pub.10.1038/nature06258
32 sg:pub.10.1038/ng.226
33 sg:pub.10.1038/ng1646
34 sg:pub.10.1038/ng2015
35 sg:pub.10.1038/nrg1657
36 https://app.dimensions.ai/details/publication/pub.1075304464
37 https://app.dimensions.ai/details/publication/pub.1082576388
38 https://app.dimensions.ai/details/publication/pub.1083283698
39 https://doi.org/10.1001/archinte.155.11.1201
40 https://doi.org/10.1001/jama.277.16.1293
41 https://doi.org/10.1001/jama.288.19.2421
42 https://doi.org/10.1002/ajh.21102
43 https://doi.org/10.1016/j.ajhg.2007.09.003
44 https://doi.org/10.1016/j.amjhyper.2004.02.019
45 https://doi.org/10.1016/j.jdiacomp.2003.12.007
46 https://doi.org/10.1016/s0272-6386(12)80266-6
47 https://doi.org/10.1016/s0378-1119(02)00455-9
48 https://doi.org/10.1046/j.1469-1809.2000.6420171.x
49 https://doi.org/10.1073/pnas.012025199
50 https://doi.org/10.1073/pnas.85.23.9119
51 https://doi.org/10.1086/301908
52 https://doi.org/10.1086/420856
53 https://doi.org/10.1086/420871
54 https://doi.org/10.1086/426405
55 https://doi.org/10.1097/01.asn.0000026493.18542.6a
56 https://doi.org/10.1097/01.asn.0000070078.66465.55
57 https://doi.org/10.1097/01.asn.0000135972.13396.6f
58 https://doi.org/10.1111/j.1525-139x.1996.tb00890.x
59 https://doi.org/10.1111/j.1600-0609.2008.01046.x
60 https://doi.org/10.1126/science.1105436
61 https://doi.org/10.1172/jci27699
62 https://doi.org/10.3892/ijmm.17.5.729
63 schema:datePublished 2008-10
64 schema:datePublishedReg 2008-10-01
65 schema:description As end-stage renal disease (ESRD) has a four times higher incidence in African Americans compared to European Americans, we hypothesized that susceptibility alleles for ESRD have a higher frequency in the West African than the European gene pool. We carried out a genome-wide admixture scan in 1,372 ESRD cases and 806 controls and found a highly significant association between excess African ancestry and nondiabetic ESRD (lod score = 5.70) but not diabetic ESRD (lod = 0.47) on chromosome 22q12. Each copy of the European ancestral allele conferred a relative risk of 0.50 (95% CI = 0.39-0.63) compared to African ancestry. Multiple common SNPs (allele frequencies ranging from 0.2 to 0.6) in the gene encoding nonmuscle myosin heavy chain type II isoform A (MYH9) were associated with two to four times greater risk of nondiabetic ESRD and accounted for a large proportion of the excess risk of ESRD observed in African compared to European Americans.
66 schema:genre research_article
67 schema:inLanguage en
68 schema:isAccessibleForFree true
69 schema:isPartOf Na7d38ee41a98401f853cd69f3d6b36d2
70 Ne1e40c25db0e4a95a1632d359a8803da
71 sg:journal.1103138
72 schema:name MYH9 is associated with nondiabetic end-stage renal disease in African Americans
73 schema:pagination 1185-1192
74 schema:productId N06d7278d75084af88a79f0e3347c3429
75 N15b83154f3a74a058d3bb1097e266ef8
76 N7e244f20b13b4780a953ea8a7ffb1fbd
77 Nabfd3c14993d41539ea4c18cb327bb16
78 Nad6b08ac927942a9b9431744239ce08d
79 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008005765
80 https://doi.org/10.1038/ng.232
81 schema:sdDatePublished 2019-04-10T14:47
82 schema:sdLicense https://scigraph.springernature.com/explorer/license/
83 schema:sdPublisher N6ecbdbabe3a1449fa24bc278487a8bd4
84 schema:url http://www.nature.com/ng/journal/v40/n10/full/ng.232.html
85 sgo:license sg:explorer/license/
86 sgo:sdDataset articles
87 rdf:type schema:ScholarlyArticle
88 N048c827fc0fc42f5a752628f3dbe10e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
89 schema:name Cohort Studies
90 rdf:type schema:DefinedTerm
91 N06d7278d75084af88a79f0e3347c3429 schema:name readcube_id
92 schema:value 2623f6caf5141b35ac62a1e8dd46b8b0021a041c083e5b7de5f31f098b3edad4
93 rdf:type schema:PropertyValue
94 N1076b6210a30409f829842eb84f3d99c rdf:first sg:person.01045313501.99
95 rdf:rest N1996e962532144e580c53ae29ab34410
96 N14725dc58d0e433e9e05f884e210950b rdf:first Nc69f8cd34ca84a2dbb11d0c307ed4982
97 rdf:rest Nea4c62d8d54745b58bc2d45b26aef248
98 N15b83154f3a74a058d3bb1097e266ef8 schema:name pubmed_id
99 schema:value 18794854
100 rdf:type schema:PropertyValue
101 N16c6e4c8be054e8e87fef5529eb2df9c schema:familyName Freedman
102 schema:givenName Barry I
103 rdf:type schema:Person
104 N1996e962532144e580c53ae29ab34410 rdf:first Na1f38deebe9d4649aaa1099bf85ce624
105 rdf:rest N9dbb894978774787b30653499db41095
106 N1e72669d5dc64d919bc3099dd3951883 schema:familyName Li
107 schema:givenName Man
108 rdf:type schema:Person
109 N253f2b53cefc40f7b973b14edcfea05c rdf:first sg:person.01052515715.67
110 rdf:rest N288338a356b444459ab76587f6c7c1c0
111 N279bebf398ac412ab3800cd9b1fd6007 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
112 schema:name Myosin Heavy Chains
113 rdf:type schema:DefinedTerm
114 N288338a356b444459ab76587f6c7c1c0 rdf:first N1e72669d5dc64d919bc3099dd3951883
115 rdf:rest Nf5fae30fb2bc46c1bb0da8406c3214d8
116 N31bf8ebd03c54385b5ec40f095281adb schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
117 schema:name Humans
118 rdf:type schema:DefinedTerm
119 N31d79a5e546c4b2096e01b26985d3501 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
120 schema:name African Americans
121 rdf:type schema:DefinedTerm
122 N345d94c2b01941e3a610ee742d292e32 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
123 schema:name Genetic Linkage
124 rdf:type schema:DefinedTerm
125 N3967e220713143c8986082f62b0cc565 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
126 schema:name Middle Aged
127 rdf:type schema:DefinedTerm
128 N3c2b41aa485e437996ac3ffa0440554f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
129 schema:name European Continental Ancestry Group
130 rdf:type schema:DefinedTerm
131 N3d99c419292942dc88aca3d6d7fa28e8 rdf:first sg:person.01207503671.81
132 rdf:rest Ned22bb3543b945c4ab67e711d1d50688
133 N3eabcca73882471f9d086ca90c024dcc rdf:first Nf78a519231874b8c99f9e185912ed699
134 rdf:rest Ne01eacfc835c4b92823400031c6c4670
135 N3fd3e9d6ea7e459390dfee0def684a1b rdf:first sg:person.01114375365.22
136 rdf:rest N8606009670ff47d4a70341c58f053cc2
137 N42c9b1578b034b40ba9ec460e67a82d2 rdf:first N5dd45a10375d4159bc7066926ba893cf
138 rdf:rest N6b220c57d66e490cbe6061ca63ea9d65
139 N475a5e68631143ad9dd74fbbdf06528b rdf:first sg:person.0602545663.05
140 rdf:rest N1076b6210a30409f829842eb84f3d99c
141 N4f8bb844888f4593a133e44f946a54c1 rdf:first sg:person.013572122437.31
142 rdf:rest N8e14cf71d6e34189b6a59e6818eb4946
143 N515dbf498e8343428ef3e7fdf80f2560 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
144 schema:name Polymorphism, Single Nucleotide
145 rdf:type schema:DefinedTerm
146 N55ee1051410f419480b9b6c80855472a schema:familyName Divers
147 schema:givenName Jasmin
148 rdf:type schema:Person
149 N5dd45a10375d4159bc7066926ba893cf schema:familyName Kimmel
150 schema:givenName Paul L
151 rdf:type schema:Person
152 N5e098be5dc694a03a9ea302aba3ce9ea rdf:first sg:person.015243204277.40
153 rdf:rest Nec345e805dda46e0b36c7c1fd7f83b7a
154 N604d56c4aa564bb98faa613fe623c26f schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
155 schema:name Chromosomes, Human, Pair 22
156 rdf:type schema:DefinedTerm
157 N62d35e7adb10439baf76a65ae909d4f0 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
158 schema:name Case-Control Studies
159 rdf:type schema:DefinedTerm
160 N65ad9b603b5746489aa4984981d215a5 rdf:first sg:person.010724122777.86
161 rdf:rest N14725dc58d0e433e9e05f884e210950b
162 N67ccafc0775d456caaa311237fcc3fa7 schema:familyName Tandon
163 schema:givenName Arti
164 rdf:type schema:Person
165 N684cc2360a09463983f6a22190632a1a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
166 schema:name Lod Score
167 rdf:type schema:DefinedTerm
168 N6b220c57d66e490cbe6061ca63ea9d65 rdf:first sg:person.014046535652.10
169 rdf:rest N475a5e68631143ad9dd74fbbdf06528b
170 N6ecbdbabe3a1449fa24bc278487a8bd4 schema:name Springer Nature - SN SciGraph project
171 rdf:type schema:Organization
172 N701b21c8de9c4c7a9b40be6c071e1739 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
173 schema:name Molecular Motor Proteins
174 rdf:type schema:DefinedTerm
175 N704e6626156a4ac3b8151f9f2c7387d7 rdf:first sg:person.0735016154.25
176 rdf:rest N65ad9b603b5746489aa4984981d215a5
177 N75cb298356484887a6e4abc6d54189e1 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
178 schema:name Chromosome Mapping
179 rdf:type schema:DefinedTerm
180 N76fb44e1dadb4ca0b71905c06001e784 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
181 schema:name Diabetes Mellitus
182 rdf:type schema:DefinedTerm
183 N780c9385d61f43159c4e9feebe44a56d schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
184 schema:name Prospective Studies
185 rdf:type schema:DefinedTerm
186 N7a90193e412d40c6ba4ab69150810dfd schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
187 schema:name Glomerulosclerosis, Focal Segmental
188 rdf:type schema:DefinedTerm
189 N7e244f20b13b4780a953ea8a7ffb1fbd schema:name nlm_unique_id
190 schema:value 9216904
191 rdf:type schema:PropertyValue
192 N7fa3869f0132477ab881be42244d39fd rdf:first Necf71da4f56d4422bb8d2fed66928b71
193 rdf:rest Na0121f1432ee4654a66573d4f84bbf86
194 N81ca32db292c47329c95a5d47b9a4a3e rdf:first N67ccafc0775d456caaa311237fcc3fa7
195 rdf:rest N3fd3e9d6ea7e459390dfee0def684a1b
196 N82f30b855ffd4d1696a10726aa617831 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
197 schema:name Kidney Failure, Chronic
198 rdf:type schema:DefinedTerm
199 N8606009670ff47d4a70341c58f053cc2 rdf:first Nf2832b20e97c477d963291779ae99731
200 rdf:rest N7fa3869f0132477ab881be42244d39fd
201 N864eeaff7f504f69b38a96e5e7c7c712 schema:familyName Patterson
202 schema:givenName Nick
203 rdf:type schema:Person
204 N876c42bb776c4d548f815156b68c3e8e schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
205 schema:name Haplotypes
206 rdf:type schema:DefinedTerm
207 N8e14cf71d6e34189b6a59e6818eb4946 rdf:first Nb11790a3fac04f608e6e58323cd63e6f
208 rdf:rest N704e6626156a4ac3b8151f9f2c7387d7
209 N8f33ba9ea72e4ddf9d1707ecd949d0f6 rdf:first N864eeaff7f504f69b38a96e5e7c7c712
210 rdf:rest N81ca32db292c47329c95a5d47b9a4a3e
211 N90ed00fb74084660a71fc84992b10230 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
212 schema:name DNA Primers
213 rdf:type schema:DefinedTerm
214 N934f71aecbbc412e830260bb93e7b138 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
215 schema:name Genome, Human
216 rdf:type schema:DefinedTerm
217 N9dbb894978774787b30653499db41095 rdf:first Nddca3e3ebf744974ba42dd3d5ac67145
218 rdf:rest Nf570fe184ddc43c5a97832c49faf1b66
219 Na0121f1432ee4654a66573d4f84bbf86 rdf:first Ne063ff2ca6844e4087495a8e1d7fcec6
220 rdf:rest N3eabcca73882471f9d086ca90c024dcc
221 Na1f38deebe9d4649aaa1099bf85ce624 schema:familyName Leehey
222 schema:givenName David J
223 rdf:type schema:Person
224 Na2413bdb8245401db0a5b54adc3e74f8 rdf:first Na39a1b1df97a40718b034b8b94ceb236
225 rdf:rest N253f2b53cefc40f7b973b14edcfea05c
226 Na39a1b1df97a40718b034b8b94ceb236 schema:familyName Reich
227 schema:givenName David
228 rdf:type schema:Person
229 Na7d38ee41a98401f853cd69f3d6b36d2 schema:issueNumber 10
230 rdf:type schema:PublicationIssue
231 Na9fbb2708eb04b42bb96c63161bcac20 schema:familyName Adler
232 schema:givenName Sharon G
233 rdf:type schema:Person
234 Nabfd3c14993d41539ea4c18cb327bb16 schema:name dimensions_id
235 schema:value pub.1008005765
236 rdf:type schema:PropertyValue
237 Nad6b08ac927942a9b9431744239ce08d schema:name doi
238 schema:value 10.1038/ng.232
239 rdf:type schema:PropertyValue
240 Nb11790a3fac04f608e6e58323cd63e6f schema:familyName Sedor
241 schema:givenName John R
242 rdf:type schema:Person
243 Nb6915bd7258d4d1b912d1a4d05e6277a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
244 schema:name Risk Factors
245 rdf:type schema:DefinedTerm
246 Nc69f8cd34ca84a2dbb11d0c307ed4982 schema:familyName Smith
247 schema:givenName Michael W
248 rdf:type schema:Person
249 Ncde77b3e827040d1b2d63cdeb44fb553 rdf:first sg:person.010012617237.52
250 rdf:rest N5e098be5dc694a03a9ea302aba3ce9ea
251 Nd31673e75c7b429d869e89233b43cd0b schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
252 schema:name Female
253 rdf:type schema:DefinedTerm
254 Nd43588a43f51462db85ae37cec2a659a schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
255 schema:name Male
256 rdf:type schema:DefinedTerm
257 Ndd51cde42c5846cc86262301b5bb1060 schema:inDefinedTermSet https://www.nlm.nih.gov/mesh/
258 schema:name Genetic Predisposition to Disease
259 rdf:type schema:DefinedTerm
260 Nddca3e3ebf744974ba42dd3d5ac67145 schema:familyName Nicholas
261 schema:givenName Susanne B
262 rdf:type schema:Person
263 Ne01eacfc835c4b92823400031c6c4670 rdf:first Na9fbb2708eb04b42bb96c63161bcac20
264 rdf:rest Nf34f404cf6fc46b2941c5bd0c2a8fe7f
265 Ne063ff2ca6844e4087495a8e1d7fcec6 schema:familyName Weir
266 schema:givenName Matthew R
267 rdf:type schema:Person
268 Ne1e40c25db0e4a95a1632d359a8803da schema:volumeNumber 40
269 rdf:type schema:PublicationVolume
270 Nea4c62d8d54745b58bc2d45b26aef248 rdf:first sg:person.0637647532.17
271 rdf:rest rdf:nil
272 Nec345e805dda46e0b36c7c1fd7f83b7a rdf:first sg:person.01314463305.15
273 rdf:rest Na2413bdb8245401db0a5b54adc3e74f8
274 Necf71da4f56d4422bb8d2fed66928b71 schema:familyName Sadler
275 schema:givenName John H
276 rdf:type schema:Person
277 Ned22bb3543b945c4ab67e711d1d50688 rdf:first N16c6e4c8be054e8e87fef5529eb2df9c
278 rdf:rest N42c9b1578b034b40ba9ec460e67a82d2
279 Nf2832b20e97c477d963291779ae99731 schema:familyName Fink
280 schema:givenName Nancy E
281 rdf:type schema:Person
282 Nf34f404cf6fc46b2941c5bd0c2a8fe7f rdf:first N55ee1051410f419480b9b6c80855472a
283 rdf:rest N3d99c419292942dc88aca3d6d7fa28e8
284 Nf570fe184ddc43c5a97832c49faf1b66 rdf:first sg:person.013117314214.24
285 rdf:rest N4f8bb844888f4593a133e44f946a54c1
286 Nf5fae30fb2bc46c1bb0da8406c3214d8 rdf:first sg:person.012700421217.04
287 rdf:rest N8f33ba9ea72e4ddf9d1707ecd949d0f6
288 Nf78a519231874b8c99f9e185912ed699 schema:familyName Abboud
289 schema:givenName Hanna E
290 rdf:type schema:Person
291 anzsrc-for:06 schema:inDefinedTermSet anzsrc-for:
292 schema:name Biological Sciences
293 rdf:type schema:DefinedTerm
294 anzsrc-for:0604 schema:inDefinedTermSet anzsrc-for:
295 schema:name Genetics
296 rdf:type schema:DefinedTerm
297 sg:grant.2404053 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
298 rdf:type schema:MonetaryGrant
299 sg:grant.2423985 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
300 rdf:type schema:MonetaryGrant
301 sg:grant.2424008 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
302 rdf:type schema:MonetaryGrant
303 sg:grant.2424016 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
304 rdf:type schema:MonetaryGrant
305 sg:grant.2424026 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
306 rdf:type schema:MonetaryGrant
307 sg:grant.2424041 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
308 rdf:type schema:MonetaryGrant
309 sg:grant.2497337 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
310 rdf:type schema:MonetaryGrant
311 sg:grant.2498315 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
312 rdf:type schema:MonetaryGrant
313 sg:grant.2498794 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
314 rdf:type schema:MonetaryGrant
315 sg:grant.2536957 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
316 rdf:type schema:MonetaryGrant
317 sg:grant.2544619 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
318 rdf:type schema:MonetaryGrant
319 sg:grant.2683090 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
320 rdf:type schema:MonetaryGrant
321 sg:grant.2689909 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
322 rdf:type schema:MonetaryGrant
323 sg:grant.2689914 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
324 rdf:type schema:MonetaryGrant
325 sg:grant.2690161 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
326 rdf:type schema:MonetaryGrant
327 sg:grant.2723619 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
328 rdf:type schema:MonetaryGrant
329 sg:grant.2723637 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
330 rdf:type schema:MonetaryGrant
331 sg:grant.2724979 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
332 rdf:type schema:MonetaryGrant
333 sg:grant.2725006 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
334 rdf:type schema:MonetaryGrant
335 sg:grant.5246872 http://pending.schema.org/fundedItem sg:pub.10.1038/ng.232
336 rdf:type schema:MonetaryGrant
337 sg:journal.1103138 schema:issn 1061-4036
338 1546-1718
339 schema:name Nature Genetics
340 rdf:type schema:Periodical
341 sg:person.010012617237.52 schema:affiliation https://www.grid.ac/institutes/grid.21107.35
342 schema:familyName Kao
343 schema:givenName W H Linda
344 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010012617237.52
345 rdf:type schema:Person
346 sg:person.01045313501.99 schema:familyName Kramp
347 schema:givenName Kristopher
348 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01045313501.99
349 rdf:type schema:Person
350 sg:person.01052515715.67 schema:familyName Berthier-Schaad
351 schema:givenName Yvette
352 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01052515715.67
353 rdf:type schema:Person
354 sg:person.010724122777.86 schema:familyName Winkler
355 schema:givenName Cheryl A
356 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.010724122777.86
357 rdf:type schema:Person
358 sg:person.01114375365.22 schema:familyName Powe
359 schema:givenName Neil R
360 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01114375365.22
361 rdf:type schema:Person
362 sg:person.01207503671.81 schema:familyName Iyengar
363 schema:givenName Sudha K
364 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01207503671.81
365 rdf:type schema:Person
366 sg:person.012700421217.04 schema:familyName Coresh
367 schema:givenName Josef
368 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.012700421217.04
369 rdf:type schema:Person
370 sg:person.013117314214.24 schema:familyName Pahl
371 schema:givenName Madeleine V
372 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013117314214.24
373 rdf:type schema:Person
374 sg:person.01314463305.15 schema:familyName Meoni
375 schema:givenName Lucy A
376 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.01314463305.15
377 rdf:type schema:Person
378 sg:person.013572122437.31 schema:familyName Schelling
379 schema:givenName Jeffrey R
380 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.013572122437.31
381 rdf:type schema:Person
382 sg:person.014046535652.10 schema:familyName Knowler
383 schema:givenName William C
384 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.014046535652.10
385 rdf:type schema:Person
386 sg:person.015243204277.40 schema:familyName Klag
387 schema:givenName Michael J
388 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.015243204277.40
389 rdf:type schema:Person
390 sg:person.0602545663.05 schema:familyName Kohn
391 schema:givenName Orly F
392 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0602545663.05
393 rdf:type schema:Person
394 sg:person.0637647532.17 schema:familyName Parekh
395 schema:givenName Rulan S
396 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0637647532.17
397 rdf:type schema:Person
398 sg:person.0735016154.25 schema:familyName Thornley-Brown
399 schema:givenName Denyse
400 schema:sameAs https://app.dimensions.ai/discover/publication?and_facet_researcher=ur.0735016154.25
401 rdf:type schema:Person
402 sg:pub.10.1007/s00439-001-0659-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033372905
403 https://doi.org/10.1007/s00439-001-0659-1
404 rdf:type schema:CreativeWork
405 sg:pub.10.1007/s004399900132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054516725
406 https://doi.org/10.1007/s004399900132
407 rdf:type schema:CreativeWork
408 sg:pub.10.1038/79069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034180464
409 https://doi.org/10.1038/79069
410 rdf:type schema:CreativeWork
411 sg:pub.10.1038/nature06258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051134045
412 https://doi.org/10.1038/nature06258
413 rdf:type schema:CreativeWork
414 sg:pub.10.1038/ng.226 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022042808
415 https://doi.org/10.1038/ng.226
416 rdf:type schema:CreativeWork
417 sg:pub.10.1038/ng1646 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030469947
418 https://doi.org/10.1038/ng1646
419 rdf:type schema:CreativeWork
420 sg:pub.10.1038/ng2015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018455308
421 https://doi.org/10.1038/ng2015
422 rdf:type schema:CreativeWork
423 sg:pub.10.1038/nrg1657 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012092299
424 https://doi.org/10.1038/nrg1657
425 rdf:type schema:CreativeWork
426 https://app.dimensions.ai/details/publication/pub.1075304464 schema:CreativeWork
427 https://app.dimensions.ai/details/publication/pub.1082576388 schema:CreativeWork
428 https://app.dimensions.ai/details/publication/pub.1083283698 schema:CreativeWork
429 https://doi.org/10.1001/archinte.155.11.1201 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054114594
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1001/jama.277.16.1293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054160859
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1001/jama.288.19.2421 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027820125
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1002/ajh.21102 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022761202
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1016/j.ajhg.2007.09.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033742684
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1016/j.amjhyper.2004.02.019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054726013
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1016/j.jdiacomp.2003.12.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003277453
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1016/s0272-6386(12)80266-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003501598
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1016/s0378-1119(02)00455-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011847147
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1046/j.1469-1809.2000.6420171.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1017036179
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1073/pnas.012025199 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044815609
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1073/pnas.85.23.9119 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053426991
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1086/301908 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058609505
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1086/420856 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058711796
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1086/420871 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058711806
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1086/426405 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058714689
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1097/01.asn.0000026493.18542.6a schema:sameAs https://app.dimensions.ai/details/publication/pub.1060318865
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1097/01.asn.0000070078.66465.55 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060319183
464 rdf:type schema:CreativeWork
465 https://doi.org/10.1097/01.asn.0000135972.13396.6f schema:sameAs https://app.dimensions.ai/details/publication/pub.1060319690
466 rdf:type schema:CreativeWork
467 https://doi.org/10.1111/j.1525-139x.1996.tb00890.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029646602
468 rdf:type schema:CreativeWork
469 https://doi.org/10.1111/j.1600-0609.2008.01046.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009334668
470 rdf:type schema:CreativeWork
471 https://doi.org/10.1126/science.1105436 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027070431
472 rdf:type schema:CreativeWork
473 https://doi.org/10.1172/jci27699 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038453425
474 rdf:type schema:CreativeWork
475 https://doi.org/10.3892/ijmm.17.5.729 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071506284
476 rdf:type schema:CreativeWork
477 https://www.grid.ac/institutes/grid.21107.35 schema:alternateName Johns Hopkins University
478 schema:name Department of Epidemiology, School of Medicine and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland 21287, USA. wkao@jhsph.edu
479 rdf:type schema:Organization
 




Preview window. Press ESC to close (or click here)


...