Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2008-08-01

AUTHORS

Robert R Graham, Chris Cotsapas, Leela Davies, Rachel Hackett, Christopher J Lessard, Joanlise M Leon, Noel P Burtt, Candace Guiducci, Melissa Parkin, Casey Gates, Robert M Plenge, Timothy W Behrens, Joan E Wither, John D Rioux, Paul R Fortin, Deborah Cunninghame Graham, Andrew K Wong, Timothy J Vyse, Mark J Daly, David Altshuler, Kathy L Moser, Patrick M Gaffney

ABSTRACT

Patrick Gaffney and colleagues report results of a genome-wide association study for systemic lupus erythematosus (SLE), identifying variants in the TNFAIP3 region on 6q23 that are strongly associated with the disease. In a related study, Lindsey Criswell and colleagues report a similar association between variants near TNFAIP3 and SLE. The same region on 6q23 has recently been associated with rheumatoid arthritis, but only a subset of risk alleles in this region seem to be common to both diseases. More... »

PAGES

1059-1061

Journal

TITLE

Nature Genetics

ISSUE

9

VOLUME

40

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng.200

DOI

http://dx.doi.org/10.1038/ng.200

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1043158572

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/19165918


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