Chromosome-scale selective sweeps shape Caenorhabditis elegans genomic diversity View Full Text


Ontology type: schema:ScholarlyArticle      Open Access: True


Article Info

DATE

2012-01-29

AUTHORS

Erik C Andersen, Justin P Gerke, Joshua A Shapiro, Jonathan R Crissman, Rajarshi Ghosh, Joshua S Bloom, Marie-Anne Félix, Leonid Kruglyak

ABSTRACT

Leonid Kruglyak and colleagues report high-throughput selective sequencing of a worldwide collection of 200 wild C. elegans strains, providing a comprehensive characterization of genetic variation in this species. They find that chromosome-scale selective sweeps have acted to reduce genetic variation and shape the C. elegans population structure in recent history.

PAGES

285-290

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/ng.1050

DOI

http://dx.doi.org/10.1038/ng.1050

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1010262159

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/22286215


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