Effects of Diamorphine on Various Neurones in the Rat Central Nervous System View Full Text


Ontology type: schema:ScholarlyArticle     


Article Info

DATE

1973-05

AUTHORS

O. LL. LLOYD

ABSTRACT

Neurones of the raphe nucleus send axons to other regions; of the central nervous system, especially the hypothalamus. These neurones synthesize serotonin, much of which is stored in cytoplasmic vesicles, where it is protected from the action of monoamine oxidase1. Accumulations of these vesicles are found within varicosities at the raphe nerve terminals2. Reser-pihe causes the vesicles to release their serotonin contents; once freed and thereby exposed to monoamine oxidase, serotonin is broken down3. Whether or not serotonin metabolism is affected by morphine and its derivatives has remained a controversial topic4. More... »

PAGES

153

References to SciGraph publications

Identifiers

URI

http://scigraph.springernature.com/pub.10.1038/newbio243153a0

DOI

http://dx.doi.org/10.1038/newbio243153a0

DIMENSIONS

https://app.dimensions.ai/details/publication/pub.1038330149

PUBMED

https://www.ncbi.nlm.nih.gov/pubmed/4515744


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